RU2720688C2 - Новые белки, специфические в отношении ангиогенеза - Google Patents

Новые белки, специфические в отношении ангиогенеза Download PDF

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RU2720688C2
RU2720688C2 RU2017128105A RU2017128105A RU2720688C2 RU 2720688 C2 RU2720688 C2 RU 2720688C2 RU 2017128105 A RU2017128105 A RU 2017128105A RU 2017128105 A RU2017128105 A RU 2017128105A RU 2720688 C2 RU2720688 C2 RU 2720688C2
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Рачида Сихам Бел Айба
Андреа Аллерсдорфер
Александер Виденман
Кристине Роте
Шейн Ольвилль
Хендрик ГИЛЛЕ
Лоран Одоли
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ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/00Medicinal preparations containing peptides
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/515Angiogenesic factors; Angiogenin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
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    • C07K2319/00Fusion polypeptide
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/515Angiogenesic factors; Angiogenin

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  • Life Sciences & Earth Sciences (AREA)
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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
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  • Marine Sciences & Fisheries (AREA)
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RU2017128105A 2015-01-28 2016-01-27 Новые белки, специфические в отношении ангиогенеза RU2720688C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15152826.2 2015-01-28
EP15152826 2015-01-28
PCT/EP2016/051657 WO2016120307A1 (en) 2015-01-28 2016-01-27 Novel proteins specific for angiogenesis

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RU2017128105A RU2017128105A (ru) 2019-03-05
RU2017128105A3 RU2017128105A3 (OSRAM) 2019-07-17
RU2720688C2 true RU2720688C2 (ru) 2020-05-12

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US (2) US10526382B2 (OSRAM)
EP (1) EP3250586B1 (OSRAM)
JP (1) JP6839087B2 (OSRAM)
KR (1) KR20170105609A (OSRAM)
CN (1) CN107207574A (OSRAM)
AU (1) AU2016212087B2 (OSRAM)
BR (1) BR112017015773A2 (OSRAM)
CA (1) CA2973640A1 (OSRAM)
DK (1) DK3250586T3 (OSRAM)
MX (1) MX384075B (OSRAM)
RU (1) RU2720688C2 (OSRAM)
SG (2) SG11201705278QA (OSRAM)
WO (1) WO2016120307A1 (OSRAM)
ZA (1) ZA201704320B (OSRAM)

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US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
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RS64002B1 (sr) 2015-05-18 2023-03-31 Pieris Pharmaceuticals Gmbh Anti-kancerski fuzioni polipeptid
EA035586B1 (ru) * 2015-11-30 2020-07-10 Пиерис Острелиа Пти Лтд. Новые антиангиогенные слитые белки
TW201725212A (zh) 2015-12-10 2017-07-16 第一三共股份有限公司 特異性於降鈣素基因相關胜肽的新穎蛋白
KR20250057128A (ko) 2015-12-30 2025-04-28 코디악 사이언시스 인코포레이티드 항체 및 이의 접합체
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WO2020201038A1 (en) 2019-03-29 2020-10-08 Pieris Pharmaceuticals Gmbh Inhaled administration of lipocalin muteins
CN114786731A (zh) 2019-10-10 2022-07-22 科达制药股份有限公司 治疗眼部病症的方法
JP2023527908A (ja) 2020-06-05 2023-06-30 ピエリス ファーマシューティカルズ ゲーエムベーハー 4-1bbをターゲティングする多量体免疫調節物質
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US20130316962A1 (en) * 2008-06-24 2013-11-28 Technische Universität München Muteins of hNGAL and related proteins with affinity for a given target
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WO2016120307A1 (en) 2016-08-04
US10526382B2 (en) 2020-01-07
SG10201906859PA (en) 2019-08-27
US20180016312A1 (en) 2018-01-18
MX384075B (es) 2025-03-14
DK3250586T3 (da) 2021-12-06
JP2018509887A (ja) 2018-04-12
MX2017009767A (es) 2018-08-15
BR112017015773A2 (pt) 2018-03-27
KR20170105609A (ko) 2017-09-19
CA2973640A1 (en) 2016-08-04
US11034738B2 (en) 2021-06-15
US20200140501A1 (en) 2020-05-07
AU2016212087B2 (en) 2019-11-07
EP3250586A1 (en) 2017-12-06
ZA201704320B (en) 2023-07-26
CN107207574A (zh) 2017-09-26
JP6839087B2 (ja) 2021-03-03
RU2017128105A3 (OSRAM) 2019-07-17
RU2017128105A (ru) 2019-03-05
AU2016212087A1 (en) 2017-07-27
EP3250586B1 (en) 2021-10-27
SG11201705278QA (en) 2017-07-28

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