RU2712049C2 - Complex biologically active additive for suppressing hair growth and methods for use thereof - Google Patents

Abstract

FIELD: chemistry.SUBSTANCE: invention relates to cosmetology and represents a complex additive for suppressing hair growth, characterized by high pH level, from 8 to 15, added to various agents, which are selected carrier for complex additive for hair growth inhibition, which contains one or more hydroxides from the following list No.1: LiOH, NaOH, KOH, RbOH, CsOH, Ca(OH), Ba(OH), Sr(OH), as well as one or more components possessing keratolytic or exfoliating property, from the following list No. 2: sea salt, including Dead Sea salt, amber powder, arsenium powder, grapeseed powder, raspberry powder, cedar pine shell powder, avocado seeds powder, almond shell powder, apricot kernel powder, hazelnut shell powder, olive berry powder, lotus seed lotus powder, rosehips powder, orange peel powder, rice husk powder, litchi powder, walnut shell powder, sugar, Moroccan volcanic clay, diatomaceous earth, kaolin, illite, polylactic acid, glycolic acid, malic acid, lactic acid, phytic acid, mandelic acid, capryloyl salicylic acid, benzoic acid, citric acid, glycyrrhetinic acid, boric acid, thioglycolic acid, carbolic acid (phenol), isodecyl salicylate, salicylic acid, zinc salicylate, silicic acid, betaine salicylate, urea, hydroxyethyl urea, diazolidinyl urea, sodium lactate, ammonium lactate, gluconolactone, barium sulphide, strontium sulphide, resorcin, green potassium soap, silver nitrate, oxolin, isotretinoin, adapalene, hexanoyl dipeptide-3 norleucine acetate, inherentline, bromelain, papain, lipase, collagenase, protease, alkaline protease, pepsin, trypsin, pancreatin, caripazymum, terrilitin, claustridiopeptidase A, somuim, chymotrypsin, chymopsin, terrilitin, subtilisin, sulfur, hydrogen peroxide, benzoyl peroxide, mercury amide chloride, papaya extract, fig fruit extract, pineapple fruit extract, wherein the components in the additive are in a certain ratio in wt. %.EFFECT: invention provides the possibility of cell destruction of hair growth zone, slowing down and termination of hair growth, splitting of fat and other cells on the way to hair growth zone and absence of skin irritation.7 cl, 2 dwg

Description

The invention relates to the field of cosmetology and medicine, describes the composition of a complex biologically active additives for suppressing hair growth at home and the method of its use in various parts of the body, characterized in that it is used on the treated area of the skin where hair growth occurs, using preliminary hair removal with the root to create a delivery channel and further delivery of a comprehensive dietary supplement to suppress hair growth to the hair growth zone. An additional distinguishing feature in order to improve the results is the use of the method of applying a complex biologically active additive to suppress hair growth in which the treated area is covered with a material impermeable to evaporation from above. Due to thermal heating, an increase in the pore size of the skin under the material is impermeable to evaporation of the substances, and therefore it is easier for the previously applied agent to penetrate the hair growth zone. It is also possible to combine (with covering the skin with a material impervious to evaporation of substances) or separate (without covering the skin with a material that is impermeable to evaporation of substances) the use of a complex biologically active additive for suppressing hair growth using the ultrasound method (ultrasonophoresis) or radio frequency lifting for better penetration of substances into the skin.

The task of the invention is to provide a composition and methods for using a complex dietary supplement for suppressing hair growth, which can be added to a selected carrier for subsequent use at home. Mostly hair growth is associated with the vital activity of the hair follicle, in which there is a hair growth zone consisting of stem cells. Slowing or stopping hair growth is achieved by the action of substances of the composition on unprotected cell membranes of the hair growth zone.

The technical result is the provision of the possibility of destruction of the cells of the hair growth zone by means permitted in medicine and cosmetology.

The difference and novelty of the additive is to improve the efficiency of the delivery process and the effect on hair growth cells, due to the presence of both components - hydroxide and keratolytic component, since their joint presence allows you to get the possibility of splitting fat and other cells that can "clog" the access channel (passage) on the way to the hair growth zone. In the case of the presence of keratolik creates a "passage in the wall" between the cells along the path to the hair growth zone and the effectiveness of the action is improved.

The experiments of the new composition (Fig. 1 and Fig. 2 can be found in Appendix No. 1) with a complex dietary supplement for suppressing hair growth relative to earlier developed prototypes according to patents RU 2599480 C2 and RU 2557994 C2 confirmed the conclusions that the use of the composition with complex a dietary supplement for suppressing hair growth has better results for delivering substances to the hair growth zone and the effectiveness of exposure to the hair growth zone.

A comprehensive dietary supplement for suppressing hair growth at home, is characterized by a high pH level from 8 to 15, which is new and distinguishes it from cosmetics and medical products available on the market, since the rest of the currently existing products mostly have pH in the range from 3 to 7 (optimal value for human skin pH balance). Another difference and novelty is the fact that currently existing cosmetic and medical products, even in rare cases, pH values of more than 7, affect only the skin surface, and in the case of a complex dietary supplement to suppress hair growth, the effect occurs at a level lower skin surface in the hair growth zone.

A significant difference and novelty is also the composition of a complex dietary supplement for suppressing hair growth at home:

A comprehensive dietary supplement for suppressing hair growth at home, added to various products (selected carrier), contains one or more hydroxides from the following list (list No. 1): LiOH, NaOH, KOH, RbOH, CsOH, Ca (OH ) ₂ , Ba (OH) ₂ , Sr (OH) ₂ , as well as one or more components with an exfoliating (keratolytic) property from the following list (list No. 2): Betaine Salicylate, Hexanoyl Dipeptide-3 Norleucine Acetate, Passiflora Quadrangularis Fruit Extract , Sutilains, Bambusa Arundinacea Leaf Extract, Maris Sal (Dead Sea Salt), Acer Saccharum (Sugar Maple) Extract, Maris Limus Extract, Amber Powder, Bambusa Arund inacea Extract, Maris Sal (Sea Salt), Bambusa Textilis Stem Extract, Bromelain, Carica Papaya (Papaya) Fruit Extract, Papain, Lipase, Collagenase, Protease, Alkaline protease, Pepsin, Trypsin, Pancreatin, Caripazim, Terrilytin, Claustridiopeptidaza , Somuim, Chymotrypsin, Chymopsin, Terrilytin, Argania Spinosa Shell Powder, Vitis Vinifera (Grape) Seed Powder, Urea, Hydroxyethyl Urea, Diazolidinyl Urea, Sodium Lactate, Malic Acid, Lactic Acid, Jojoba Esters, Glycolic Fig Fruit Extract, Bambusa Vulgaris Extract, Bambusa Arundinacea Stem Extract, Ananas Sativus (Pineapple) Fruit Extract, Ammonium Lactate, Rubus Idaeus (Raspberry) Seed Powder, Pinus Sibirica Shell Powder, Persea Gratissima (Avocado) Seed Powder, Polylactic Acid (Carrot) Root Powder, Sugar, Rhassoul (Moroccan lava clay), Prunus Amygdalus Dulcis Shell Powder, Prunus Armeniaca (Apricot) Seed Powder, Corylus Avellana (Hazel) Shell Powder, Prunus Avium (Sweet Cherry) Seed E xtract, Citrus Grandis (Grapefruit) Peel Extract, Margarita Powder, Isodecyl Salicylate, Olea Europaea (Olive) Seed Powder, Luffa Cylindrica Fruit Extract, Nelumbo Nucifera Seed Powder, Diatomaceous Earth, Hydrated Silica, Rosa Canina Seed Powder D Citrus Orange, Citrus ) Peel Powder, Oryza Sativa (Rice) Hull Powder, Litchi Chinensis Seed Powder, Juglans Regia (Persian Walnut) Shell Powder, Illite, Salicylic Acid, Hydroxyethyl Urea, Zinc Salicylate, Subtilisin, Phytic Acid, Mandelic acid, Kaolin, Gluconolactone Salicylic Acid, Benzoic Acid, Citric Acid, Glycyrrhetinic Acid, Boric acid, Thioglycolic acid, Sulfur, Hydrogen peroxide, Benzoyl peroxide, Barium Sulfide, Strontium Sulfide, Resorcinol, Carbolicum Acid (Phenol), Sapo viridis (green soap, green soap) Silver Nitrate, Oxolinum, Ichthyolum, Naphthalanum liquidum raffinatum, Isotretinoin, Adapalenum, in the following ratio of components, wt. % .:

- one or more hydroxides from the following list No. 1: LiOH, NaOH, KOH, RbOH, CsOH, Ca (OH) ₂ , Ba (OH) ₂ , Sr (OH) ₂ from 0.001 to 99.999%

- one or more keratolytic components from list No. 2 from 0.001 to 99.999%

An additional novelty and difference from cosmetic and medical products on the market is the fact that when a complex biologically active additive is added to suppress hair growth in a cosmetic or medical (non-food) product, the pH level of the product into which the additive is introduced also increases to pH values from 8 up to 15, because currently existing products have pH in the range from 3 to 7 (the optimal value for the pH balance of the skin in humans), which is new for these funds.

A comprehensive dietary supplement for growth suppression can be produced in one of the following forms most common in medicine and cosmetics: solution, cream, emulsion, lotion, ointment, paste, suspension, tablet, powder, powder, gel, stick, aerosol.

A comprehensive dietary supplement to inhibit hair growth is administered in an amount of from 0.01 to 35% by weight of the basic composition (raw materials), depending on the degree of the desired effect that they want to receive.

The invention provides the possibility of destruction of cells responsible for hair growth by means permitted in medicine and cosmetology.

The invention relates to cosmetology and medicine, in particular to means and methods for removing unwanted hair.

A known composition based on salicylic acid, ethanol and water to prevent hair growth (RF patent No. 2193877, IPC AK61/06).

A known method and tool for removing hair and stratum corneum on the human body (RF patent No. 2292199, published January 27, 2007), in which to remove hair and stratum corneum use a product containing fructose, walnut oil, propolis, decoction of medicinal plants: chamomile , oak bark, licorice, and St. John's wort, taken in equal proportions, and aloe vera juice and an acidifier selected from the group: lemon juice, citric acid, apple cider vinegar, cranberry juice - at a certain ratio. In this case, the sticky elastic resinous mass, stretching it, is applied to the surface of the skin in the opposite direction to hair growth. The specified procedure is repeated after 5-6 weeks, 5-10 procedures are carried out on the course. A disadvantage of the known methods is the duration of the course and the absence of guaranteed damage to the hair papilla at the same time. To effectively remove unwanted hair, a tool based on resin of coniferous plants, alcoholic extract of plants and a physiologically acceptable organic acid is also used (RF patent No. 2057526, published June 10, 1996). When using this tool, the effect is achieved due to mechanical hair removal - pulling.

Tests of the claimed complex biologically active additives for suppressing hair growth at home were carried out on a control group of 10 people.

For the first 5 people, they used a liquid composition based on salicylic acid, ethanol and water, according to the instructions (removed the hair with the root, then applied the active liquid with an interval of three weeks). A decrease in hair growth of up to 10% was noted, which corresponded to the declared property of the liquid composition.

For the second group of 5 people, a complex dietary supplement was used to suppress hair growth at home, after hair removal with a root with an interval of three weeks. There was a complete lack of hair growth in the treated area of the skin, where the hair was in the anagen stage. No cases of skin irritation were detected.

Claims (10)

1. A comprehensive hair growth suppressant, characterized by a high pH level, from 8 to 15, added to various products that are the carrier of choice for a comprehensive hair growth suppressant that contains one or more hydroxides from the following list No. 1 : LiOH, NaOH, KOH, RbOH, CsOH, Ca (OH) ₂ , Ba (OH) ₂ , Sr (OH) ₂ , as well as one or more components with keratolytic or exfoliating properties, from the following list No. 2: sea salt including Dead Sea salt, amber powder, ar powder prickly seeds, grape seed powder, raspberry seed powder, cedar pine shell powder, avocado seed powder, almond shell powder, apricot kernel powder, hazelnut shell powder, olive seed powder, walnut lotus seed powder, rosehip powder, orange peel powder, rice husk powder, lychee powder, walnut shell powder, sugar, Moroccan volcanic clay, diatomaceous earth, kaolin, illite, polylactic acid, glycolic acid, malic acid, lactic acid, fit new acid, mandelic acid, capryloyl salicylic acid, benzoic acid, citric acid, glycyrrhetinic acid, boric acid, thioglycolic acid, carbolic acid (phenol), isodecyl salicylate, salicylic acid, zinc salicylate, silicic acid, betaine salicylate, urea, urea, urea, , urea diazolidinyl, sodium lactate, ammonium lactate, gluconolactone, barium sulfide, strontium sulfide, resorcinol, green potassium soap, silver nitrate, oxolin, isotretinoin, adapalene, hexanoyl dipeptide-3 norleucine ac tat, sulomaline, bromelain, papain, lipase, collagenase, protease, alkaline protease, pepsin, trypsin, pancreatin, karipazim, terrilithin, claustridiopeptidase A, somim, chymotrypsin, chymopsin, terrylitin, subtilisin, sulfur dioxide, peroxide, hydrogen peroxide , papaya fruit extract, fig fruit extract, pineapple fruit extract in the following ratio of components, wt. %: - one or more hydroxides from the following list No. 1: LiOH, NaOH, KOH, RbOH, CsOH, Ca (OH) ₂ , Ba (OH) ₂ , Sr (OH) ₂ from 0.01 to 99.99%, - one or more components from list No. 2 from 0.01 to 99.99%. 2. A comprehensive additive for suppressing hair growth according to claim 1, characterized in that the release form may be: solution, cream, emulsion, lotion, ointment, paste, suspension, tablet, powder, powder, gel, stick, aerosol. 3. A cosmetic product for suppressing hair growth, characterized in that it contains a complex additive for suppressing hair growth according to any one of paragraphs. 1, 2 and its pH level from 8 to 15. 4. Cosmetic product according to paragraphs. 1-3, characterized in that it contains a complex additive for suppressing hair growth in an amount of from 0.01 to 35% by weight of the basic composition of the raw materials of the cosmetic product. 5. The method of using complex additives to suppress hair growth according to any one of paragraphs. 1-4, including the treatment of the skin area where hair growth occurs, using preliminary hair removal with a root to create a delivery channel and further delivery of a complex additive to suppress hair growth to the hair growth zone. 6. The method of using the complex additive for suppressing hair growth according to claim 5, characterized in that the treated area is covered with a material impervious to evaporation of substances from above. 7. The method of using a complex additive for suppressing hair growth according to claims 5-6, characterized in that the method of ultrasound or ultraphonophoresis or radio frequency lifting is used to better penetrate the substances into the skin.

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