RU2690841C1 - Способы лечения патологических состояний глаза с помощью имплантата с долговременной доставкой лекарственного вещества - Google Patents

Способы лечения патологических состояний глаза с помощью имплантата с долговременной доставкой лекарственного вещества Download PDF

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RU2690841C1
RU2690841C1 RU2016119132A RU2016119132A RU2690841C1 RU 2690841 C1 RU2690841 C1 RU 2690841C1 RU 2016119132 A RU2016119132 A RU 2016119132A RU 2016119132 A RU2016119132 A RU 2016119132A RU 2690841 C1 RU2690841 C1 RU 2690841C1
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implant
biodegradable
eye
months
biodegradable implant
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RU2016119132A
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English (en)
Russian (ru)
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RU2016119132A (ru
Inventor
Джейн-Гуо ШИА
Рауль БАГАТ
Венди М. БЛАНДА
Тьерри НИВАГЖИОЛИ
Линь ПЭН
Дэвид ЧОУ
Дэвид А. ВЕБЕР
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Аллерган, Инк.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
RU2016119132A 2013-11-15 2014-11-14 Способы лечения патологических состояний глаза с помощью имплантата с долговременной доставкой лекарственного вещества RU2690841C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361904887P 2013-11-15 2013-11-15
US61/904,887 2013-11-15
PCT/US2014/065804 WO2015073895A1 (en) 2013-11-15 2014-11-14 Methods of treatment of ocular conditions with a sustained drug delivery implant

Publications (2)

Publication Number Publication Date
RU2016119132A RU2016119132A (ru) 2017-12-20
RU2690841C1 true RU2690841C1 (ru) 2019-06-06

Family

ID=52001114

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016119132A RU2690841C1 (ru) 2013-11-15 2014-11-14 Способы лечения патологических состояний глаза с помощью имплантата с долговременной доставкой лекарственного вещества

Country Status (24)

Country Link
US (2) US20150140062A1 (enExample)
EP (2) EP3714875A1 (enExample)
JP (2) JP6675307B2 (enExample)
KR (3) KR20240058976A (enExample)
CN (1) CN105764517A (enExample)
AU (4) AU2014348369B2 (enExample)
CA (1) CA2929689A1 (enExample)
CL (1) CL2016001167A1 (enExample)
CY (1) CY1123344T1 (enExample)
DK (1) DK3068403T3 (enExample)
ES (1) ES2819215T3 (enExample)
HU (1) HUE050913T2 (enExample)
IL (2) IL245548A0 (enExample)
MX (2) MX2016006334A (enExample)
MY (1) MY176039A (enExample)
NZ (1) NZ719953A (enExample)
PH (1) PH12016500869A1 (enExample)
PL (1) PL3068403T3 (enExample)
PT (1) PT3068403T (enExample)
RU (1) RU2690841C1 (enExample)
SG (1) SG10201809363SA (enExample)
SI (1) SI3068403T1 (enExample)
UA (1) UA122117C2 (enExample)
WO (1) WO2015073895A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115337254A (zh) * 2015-07-23 2022-11-15 爱瑞制药公司 用于治疗眼病的玻璃体内药物递送系统
JP2019534063A (ja) 2016-09-02 2019-11-28 エンビシャ セラピューティクス インコーポレイテッド インプラントアプリケータ
MX2020012458A (es) 2018-05-24 2021-04-28 Celanese Eva Performance Polymers Llc Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular.
US11689849B2 (en) 2018-05-24 2023-06-27 Nureva, Inc. Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones
US11690806B2 (en) 2018-05-24 2023-07-04 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
IL299769A (en) * 2020-07-16 2023-03-01 Ocular Therapeutix Inc Ocular insert containing a glucocorticoid
WO2022231930A1 (en) 2021-04-26 2022-11-03 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2389479C2 (ru) * 2004-08-13 2010-05-20 Аллерган, Инк. Глазной имплантат, изготавливаемый способом двойной экструзии

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US6726918B1 (en) 2000-07-05 2004-04-27 Oculex Pharmaceuticals, Inc. Methods for treating inflammation-mediated conditions of the eye
WO2002043785A2 (en) 2000-11-29 2002-06-06 Oculex Pharmaceuticals, Inc. Intraocular implants for preventing transplant rejection in the eye
US20050244469A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Extended therapeutic effect ocular implant treatments
US8119154B2 (en) 2004-04-30 2012-02-21 Allergan, Inc. Sustained release intraocular implants and related methods
US8685435B2 (en) * 2004-04-30 2014-04-01 Allergan, Inc. Extended release biodegradable ocular implants
US20050244500A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Intravitreal implants in conjuction with photodynamic therapy to improve vision
US20090082321A1 (en) * 2007-09-21 2009-03-26 Allergan, Inc. Steroid containing drug delivery systems
CA2827082A1 (en) * 2011-02-11 2012-08-16 Psivida Us, Inc. Methods of treating macular edema using antiedema therapeutics

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2389479C2 (ru) * 2004-08-13 2010-05-20 Аллерган, Инк. Глазной имплантат, изготавливаемый способом двойной экструзии

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WILLIAM M BOYD, M.D. CROSS-DISCIPLINE TEAM LEADER REVIEW, NDA 22-315, OZURDEX (dexamethasone intravitreal implant)/CENTER FOR DRUG EVALUATION AND RESEARCH, 17.06.2009 (URL:http://www.accessdata.fda.gov/drugsatfda_docs/nda/2009/022315s000_CrossR.pdf). *

Also Published As

Publication number Publication date
AU2014348369A1 (en) 2016-06-09
CA2929689A1 (en) 2015-05-21
WO2015073895A1 (en) 2015-05-21
US20250319031A1 (en) 2025-10-16
CY1123344T1 (el) 2021-12-31
AU2024205640B2 (en) 2025-10-23
HUE050913T2 (hu) 2021-01-28
EP3714875A1 (en) 2020-09-30
IL245548A0 (en) 2016-06-30
PT3068403T (pt) 2020-09-18
SG10201809363SA (en) 2018-11-29
KR20220082934A (ko) 2022-06-17
MX2016006334A (es) 2016-09-06
EP3068403B2 (en) 2025-12-03
AU2022204607A1 (en) 2022-07-21
MY176039A (en) 2020-07-22
KR20160085847A (ko) 2016-07-18
KR20240058976A (ko) 2024-05-07
CN105764517A (zh) 2016-07-13
PH12016500869B1 (en) 2016-07-04
PH12016500869A1 (en) 2016-07-04
JP2016538292A (ja) 2016-12-08
MX2022002306A (es) 2022-03-25
NZ719953A (en) 2022-01-28
KR102475746B1 (ko) 2022-12-08
SI3068403T1 (sl) 2020-11-30
CL2016001167A1 (es) 2017-01-06
JP2020055862A (ja) 2020-04-09
EP3068403A1 (en) 2016-09-21
US20150140062A1 (en) 2015-05-21
DK3068403T3 (da) 2020-09-07
RU2016119132A (ru) 2017-12-20
UA122117C2 (uk) 2020-09-25
AU2024205640A1 (en) 2024-08-29
JP6675307B2 (ja) 2020-04-01
JP7022735B2 (ja) 2022-02-18
AU2020204362A1 (en) 2020-07-23
AU2014348369B2 (en) 2020-04-02
IL290837A (en) 2022-04-01
ES2819215T3 (es) 2021-04-15
PL3068403T3 (pl) 2021-01-11
EP3068403B1 (en) 2020-06-17

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