RU2659952C1 - Bleaching cleanser of dentures - Google Patents

Abstract

FIELD: medicine; hygiene.

SUBSTANCE: invention relates to dentistry and hygiene and is intended for cleaning, bleaching and disinfection of installed and removable dentures, other dental structures and surgical instruments. Invention consists in that the whitening cleanser of dentures is prepared on water for injection and contains 2.0–10.0 wt% of sodium bicarbonate, 3±0.3 wt% of hydrogen peroxide and oxygen gas at an overpressure of 0.2 atm at 8 °C. Agent is heated to a temperature of 37–42 °C.

EFFECT: claimed means provides cleaning, deodorization, bleaching and disinfection of dentures and surgical instruments with traces of blood and pus due to hyperthermic softening, alkaline saponification, cavitation loosening, dissolution and oxidative decolorization.

1 cl

Description

The invention relates to pharmacology, pharmacy, cosmetology, dentistry, surgery, hygiene and, in particular, to dental practice and is intended for cleaning, whitening and disinfection of installed and removable dentures, other dental structures, dental and surgical instruments.

Known cold composition for cleaning dentures, containing bleach in the form of an inorganic persal selected from alkali metal persulfates, alkali metal perborates and mixtures thereof, a rapidly emitting gas generator, which is an effervescent pair of (bi) carbonate acid, and 0.01% - 25%, demethicone copolyol selected from alkyl and alkoxy dimethicone copolyols having a specific formula (RU 2163479).

The disadvantage of the tool is a narrow scope, low efficiency, speed and safety, since the tool is not ready for use and is a cold, dry, heterogeneous mixture of inorganic persol, copolyol and a potential generator of violently released gas at an undetermined temperature. In this case, most likely, the tool has a room temperature, that is, about 24-26 ° C. However, the use of the product at a temperature below the human body temperature has a hypothermic effect, which increases the viscosity of plaque, blood stains and pus, therefore, enhances their adhesion to the denture, which reduces the speed and effectiveness of its cleaning.

In this case, the generator of violently released gas is represented by an inhomogeneous mixture of dry acid powder and dry powder (bi) carbonate, which do not interact with each other and therefore do not emit gas. The fact is that water is needed for the rapid evolution of gas. However, the known tool does not provide the presence of chemically pure water. That is why the known composition is not ready for the rapid evolution of gas and for cleaning dentures in the human oral cavity and beyond, in particular in the container in which the denture can be placed after it is removed from the jaw. Moreover, without water, the known composition contaminates dentures, leaves its ingredients on their surface and does not provide flushing from itself and plaque.

In addition, the known tool is not intended for cleaning dentures in the oral cavity.

Another disadvantage of the known composition is the absence in its composition of a specific solvent. The fact is that dentures cannot be cleaned “dry”, because with dry cleaning the “cleaning” material can spoil the surface of the denture due to abrasive properties, and with repeated cleaning it can significantly reduce the size of the denture as a whole, because such dry cleaning "Dry" peeling of the surface of the denture. This leads to the fact that the prosthesis ceases to correspond to the size of the jaw of the patient and becomes defective, which requires premature replacement of it with a new prosthesis.

The absence of chemically pure water in the known product leads to the fact that the consumer chooses the water. At the same time, someone can use tap water, someone can use water for injection, someone can use boiled water, and someone can use unboiled water. At the same time, one part of consumers can use water of good quality, another part of consumers can mistakenly or ignorantly use low quality water and even bad water (for example, process water). Therefore, the water used by the consumer in some cases may contain a contagious onset and various substances with potential chemical, physico-chemical, immunological activity and aggressiveness (for example, allergens of plant origin).

The low quality of water, which the consumer uses to dissolve the known composition, does not standardize the “working” solution obtained by dissolving the known composition in “water”, and therefore reduces the quality of the denture cleaning. In particular, the known agent does not provide stable alkalinity of the working solution with an optimal pH value. Therefore, the working solution has a low saponifying and washing activity.

In addition, the disadvantage of the known means is that as a result of the interaction of the known composition with water, a working solution with inhomogeneous physicochemical properties is initially formed. The fact is that the generator of violently released gas, which is an effervescent pair of (bi) carbonate-acid, is represented in the known composition by a mixture of dry powders of acid and carbonate with hydrolytic alkaline activity. Moreover, the known composition does not ensure uniformity of the mixture, equality of solubility, disintegration of powders and chemical reactivity of the reactants, the commensurability of their interacting masses, and also the known tool does not ensure uniform dissolution of the composition in the entire selected volume of water, since the known composition does not provide immediate dissolution and uniform distribution of ingredients in the entire selected volume of water. Moreover, the known composition allows for the presence of insoluble ingredients and the introduction of the composition into water as necessary. Most likely, the composition dips into the water from above. After the composition is in water, it sinks in it and sinks to the very bottom, since the known tool has a specific gravity in excess of the specific gravity of water. At the same time, the water begins to dissolve successively and alternately the lumps of dry substances encountered on its way when soaking the dry mass. However, the composition does not provide the simultaneous dissolution of optimal amounts of acid and alkali in water. Therefore, different volumes of the solution are obtained either acidic, then alkaline, then neutral. In this case, microvolumes of solutions appear that have a pH of less than 7.0 (when dissolving the acid), then more than 7.0 (when dissolving the carbonate). In this regard, the known means in the process of dissolution in water does not ensure the uniformity of its physico-chemical properties and, in particular, alkalinity. The fact is that in fact, in the process of dissolving a known composition, water periodically and randomly changes its acidity. Therefore, the known composition in the process of dissolution does not provide a stable pH in the entire volume of the working solution. In this regard, the use of the composition leads to the fact that some parts of the surface of the denture are periodically exposed to a solution with unstable (changing) acidity, namely it is exposed to either an acid solution, an alkali solution, or a solution with a neutral pH. In this case, the organic acid solution immediately strengthens (“welds”) the organic masses (blood, pus, etc.) to the surface of the prosthesis due to the denaturing effect on the proteins. Therefore, the composition has low efficiency and safety.

Another disadvantage of the known composition is that it does not provide gas formation in the entire water column at the same time and evenly. The fact is that gas is formed only during a chemical reaction that occurs between an acid solution and an alkaline salt solution. Therefore, initially the composition must dissolve. In this case, gas bubbles are formed in the working solution only at the location of the solid powders of the composition. In other places, or rather, where the composition did not hit, gas bubbles do not form, and therefore the water in these places for some time remains water, but not a “working” solution. In other words, water does not immediately turn into a working solution and therefore does not initially acquire the properties of a “cleaner” of a denture. Only gradually and only after the completion of the dissolution of all solid particles can water turn into a complete working solution. Usually this is achieved 60 seconds after the composition is placed in water, and by this time gas evolution ceases. Therefore, even after the completion of the process of interaction of the ingredients with each other and the water and after the water composition is equalized, the working solution in its entirety reduces its effectiveness, since by this time gas evolution stops in the solution.

Moreover, the known composition does not provide the formation of oxygen gas. The fact is that the interaction of acid and (bi) carbonate produces carbon dioxide. At the same time, carbon dioxide does not have a deodorizing effect. At the same time, oxygen gas has a good deodorizing effect. But the known tool does not provide the formation of oxygen gas.

A disadvantage of the known composition is that it does not provide a colorless working solution. Therefore, the use of the known composition allows the formation of a working solution with any color, namely red, orange, yellow, green, blue, blue or purple. In this regard, the known tool allows the coloring of the denture in any color and with any intensity. In other words, the known tool allows the denture to be contaminated with dye.

In addition, the known agent does not have the ability to quickly and effectively dissolve and discolor pus and blood. Therefore, the tool does not provide urgent removal and discoloration of plaque with a splash of blood and pus, that is, it does not provide high speed and efficiency of whitening and cleaning of the denture.

And finally, the known composition does not provide a final rinse of the denture with the finished solution. Moreover, for the final washing of the denture after cleaning it with a known product, it is necessary to use a special bleaching rinse that can discolor the blood and remove all the ingredients of the known composition from the surface of the prosthesis. The fact is that the known composition contains chemically active ingredients that can cause local aggressive effects on the denture and local irritating effects on the mucous membrane in the oral cavity. Therefore, for the safety of the denture, the exclusion of local irritating and cauterizing effects on the mucous membranes in the patient’s oral cavity and the development of local inflammation in the oral cavity, it is necessary to remove the remains of the working solution from the surface of the denture. For this, the denture should be cleaned of the known composition using a rinse aid. In other words, after treating the denture with a solution obtained using the known composition, the denture is not ready to be placed in the patient’s oral cavity, as it remains stained with the remnants of the composition.

In this regard, the tool has a narrow scope, low speed, efficiency, safety and uniformity of cleaning and bleaching of the denture.

Known cold effervescent tablet for cleaning dentures, including sodium carbonate, sodium bicarbonate, sodium perborate, PVK-30, blue dye, citric acid, sodium lauryl sulfoacetate, potassium monopersulfate, tetracetylethylenediamine, sodium benzoate, proteolytic enzymes, peppermint essential oil, 8000 peppermint oil , polymethylsiloxane (http://www.provizor-online.ru/2013/04/korega_tabletki_Corega_tabs. Found on the Internet 02/18/2017).

The disadvantage of the tool is the narrow scope, low efficiency, speed and safety, because the tool is not ready for immediate cleaning of the prosthesis, as it is a dry tablet consisting of sodium carbonate, sodium bicarbonate, sodium perborate, PVK-30, dye blue, citric acid , sodium lauryl sulfoacetate, potassium monopersulfate, tetraacetylethylenediamine, sodium benzoate, proteolytic enzymes, peppermint essential oil, polyethylene glycol 8000 and polymethylsiloxane. The fact is that the tablet itself is not ready to clean the denture, since dentures cannot be cleaned with dry tablets. This is due to the fact that during dry cleaning with a tablet due to its abrasive properties, the surface of the prosthesis can deteriorate, its aesthetic condition deteriorates and the size of the denture as a whole decreases, which makes it defective.

In addition, a well-known tablet cannot be injected into the oral cavity of people, since it can dissolve tooth enamel and cause caries, and is also able to burn mucous membranes and cause gingivitis, stomatitis and glossitis. Moreover, the known tablet has a temperature below 37 ° C and does not provide a temperature increase to 37-42 ° C, because it does not contain a heater. Therefore, the known tool does not provide effective hyperthermic softening of plaque, blood fragments and pus.

To clean the denture, you need to prepare a solution using a tablet and chemically pure water. It is chemically pure water that is the main ingredient that provides high-quality washing and cleaning of dentures. But the well-known tablet does not provide the presence of such water in its composition.

The absence of chemically pure water in the known product leads to the fact that a significant part of consumers use low-quality water, as some consumers use tap water. And this water is often dirty.

Therefore, the known effervescent tablet does not provide the use of chemically pure water by all consumers and the preparation of a working solution having a standard composition and properties, therefore, it does not provide high efficiency and accuracy of cleaning the denture. In particular, in some cases, the consumer may use raw water, which may contain various chemical ingredients with potential chemical and physico-chemical activity and aggressiveness (in particular, chlorine may be such an aggressive ingredient).

In addition, when a known tablet interacts with water, a working solution with inhomogeneous physicochemical properties is initially formed. The fact is that tablets are prepared by pressing, so they are heavier than water and drown in it. A well-known tablet drowns in water and sinks in it to the very bottom, where it then interacts with water. At the bottom there are two processes: disintegration and solubility of the tablet. These processes occur only in one place, namely, where the tablet lies, since the known tool does not provide an even distribution of the contents of the tablet in the entire volume of water used. Therefore, initially different volumes of the solution have different acidity (alkalinity). In this case, microvolumes of solutions appear that have a pH of less than 7.0 (when dissolving acids), then more than 7.0 (when dissolving alkaline salts). In this regard, the known means in the process of dissolution in water does not ensure the uniformity of its physico-chemical properties and, in particular, alkalinity. In this regard, the use of the known tablet leads to the fact that almost every area of a denture immersed in water is periodically exposed to a solution with an unstable (changing) acidity, namely it is exposed to either an acid solution, an alkali solution, or a solution with a neutral pH. In this case, the organic acid solution coagulates the proteins, therefore it strengthens the connection of organic masses (blood, pus, etc.) with the surface of the denture. Therefore, the known composition has low efficiency and safety.

Another disadvantage of the known means is that it does not provide for the formation of gas bubbles in the entire water column (cavitation) simultaneously and evenly. The fact is that gas is formed only during a chemical reaction that occurs between an acid solution and an alkaline salt solution. Therefore, initially the composition must dissolve. In this case, gas bubbles form in the working solution only in the place where the tablet is located. In other places, and more precisely where there is no tablet, gas bubbles do not form, and therefore the water in these places for some time remains water, but not a “working” solution. In other words, water does not turn into a “boiling” solution and therefore does not acquire the properties of a “cleaner” of a denture. Therefore, the known tablet has low efficiency when cleaning a denture.

In addition, the known effervescent tablet does not provide the formation of oxygen gas, therefore, it has low deodorizing activity. At the same time, it is oxygen gas that has a pronounced deodorizing effect.

A disadvantage of the known effervescent tablet is that it does not provide a colorless working solution. Moreover, it contains blue dye in its composition. Therefore, the use of a known tablet allows the formation of a working solution with a blue or other color up to a bright and saturated color. In this regard, the known tool allows the coloring of the denture in blue or another color with any intensity. In other words, the tablet allows the prosthesis to be contaminated with dye until it is painted in a bright and saturated color of all the colors of the rainbow.

In addition, the known agent is not able to quickly and efficiently dissolve and discolor pus and blood. Therefore, the tool does not provide urgent loosening, dissolution, whitening and removal of plaque with traces of blood and pus.

And finally, the known tablet does not provide a final rinse of the denture with the finished solution. Moreover, for the final washing of the denture after interacting with a known agent, it is required to use a special rinse aid that can remove all the ingredients of the known tablet from the surface of the denture. The fact is that a well-known tablet contains chemically active ingredients that can cause local irritating effects on the mucous membrane in the human oral cavity. Therefore, after the interaction of the denture with a known means to eliminate local irritating effects on the mucous membranes in the oral cavity, it is necessary to remove the remains of such a solution from the surface of the denture before installing the denture in the human oral cavity. Most likely this can be achieved using a safe solution with rinsing properties.

In this regard, the tool does not provide a wide scope, high speed, efficiency, safety and uniformity of cleaning and bleaching of the prosthesis.

A denture cleaning agent is known, which is an effervescent tablet containing components that dissolve plaque and organic matter on the surface of the prosthesis and disinfect the prosthesis (http: //xn----8sbjbebmif2ajkocbdrzrcd50a.xn--plai/sovety/157-pravila- i-rekomendatsii-po-ukhodu-za-zubnymi-protezami. Found on the Internet 02/18/2017).

The disadvantage of the tool is a narrow scope, low efficiency, speed and safety, because the tool is not ready for immediate cleaning, as it is a cold and dry tablet made by pressing dry substances. The fact is that dentures cannot be cleaned with dry tablets. This is explained by the fact that a dry tablet has pronounced abrasive properties, therefore, when cleaning a prosthesis with a tablet, the surface of the prosthesis can deteriorate due to its abrasive properties, its aesthetic condition worsens and the entire size of the denture decreases, which makes it defective and needs to be replaced.

Moreover, the known agent does not contain a heating element, does not provide an increase in temperature to 37-42 ° C, therefore, does not create conditions for effective hyperthermic softening of plaque, food debris, blood and pus.

To clean the denture, you need to prepare a solution using a tablet and chemically pure water. It is chemically pure water that is the main ingredient that provides the washing and cleaning of dentures. But the known tool does not provide the presence of such water in its composition.

The absence of chemically pure water in the known product leads to the fact that all consumers use water of different composition and quality. Moreover, sometimes even distilled and drinking water may turn out to be not chemically pure water, but a solution of various mineral substances and gases. Therefore, the well-known tablet does not provide the use of chemically pure water by all consumers and the preparation of a working solution having a standard composition and properties, therefore, it does not provide high efficiency and accuracy of cleaning the denture. In particular, in some cases, the consumer may use raw water, which may contain various chemical and microbiological agents with potential chemical and physico-chemical activity and aggressiveness (in particular, chlorine or viruses that cause AIDS or prion may be such an aggressive agent disease).

In addition, when a known tablet interacts with water, a working solution with inhomogeneous physicochemical properties is initially formed. The fact is that tablets are prepared by pressing, so they are heavier than water and drown in it. A well-known tablet drowns in water and sinks in it to the very bottom, where its main interaction with water occurs, in particular disintegration and solubility of the tablet. These processes occur only in one place, namely, where the tablet lies, since the known tool does not provide an even distribution of the contents of the tablet in the entire volume of water used. Therefore, initially different volumes of the solution have different concentrations of soluble ingredients and different acidity (alkalinity). Moreover, microvolumes of solutions with different concentrations of active ingredients periodically appear in the entire volume of water, which also have a pH of less than 7.0 (when dissolving acids), then more than 7.0 (when dissolving alkaline salts). In this regard, the known means in the process of dissolution in water does not immediately achieve uniformity of its physicochemical properties and, in particular, alkalinity. Therefore, the known tablet leads to the fact that almost every part of the denture immersed in water is periodically exposed to a solution with a different composition and with a different concentration of ingredients and with unstable (changing) acidity: either an acid solution, then an alkali solution, or a neutral solution. In this case, an organic acid solution strengthens (“welds”) organic matter (blood, pus, etc.) to the surface of the prosthesis. Therefore, the known composition has low efficiency and safety.

Another disadvantage of the known means is that it does not provide gas formation in the entire water column at the same time and evenly. The fact is that gas is formed only during a chemical reaction that occurs between an acid solution and an alkaline salt (bicarbonate) solution. Therefore, initially the composition must dissolve. In this case, gas bubbles form in the working solution only in the place where the tablet will be. In other parts of the water, more precisely where there is no tablet, gas bubbles do not form, and therefore the water in these places for some time remains water, but not a “working” solution. In other words, water does not turn into a solution immediately and immediately in its entirety, therefore for some time it does not have the quality of a quality “cleaner” of a denture. As a rule, the disintegration of the tablet ends in 1 minute. Therefore, the known tablet has a low speed and efficiency when cleaning a denture.

In addition, the known effervescent tablet does not provide the formation of an oxygen gas, which has a pronounced oxidizing and deodorizing effect. Therefore, the known tablet does not have the most effective oxidizing and deodorizing effect.

A disadvantage of the known effervescent tablet is that it does not provide a colorless working solution. In particular, the use of a known tablet allows the formation of a working solution with a blue or other color up to bright and saturated colors, which means that an effervescent tablet allows the denture to be painted in blue and a different color with any intensity. In other words, the tablet allows contamination of the prosthesis with dye.

In addition, the known tool is not able to quickly and efficiently dissolve and discolor blood, thick and sticky pus. Therefore, the tool does not provide urgent cleaning and whitening of the denture.

And finally, the known effervescent tablet does not provide a final rinse of the denture with a ready-made solution. Moreover, the use of a tablet for cleaning the prosthesis requires the use of a special rinse for its final washing, which will be able to remove the remains of all the effervescent tablet ingredients from the surface of the prosthesis. The fact is that the well-known effervescent tablet contains components that dissolve plaque and organic substances and disinfect the surface. In other words, the well-known effervescent tablet contains aggressive chemical components that, when dissolved in ordinary water, turn it into a disinfecting solvent for organic substances. Therefore, for the safety of the denture and the exclusion of local irritating effects on the mucous membranes in the patient’s oral cavity, it is necessary to remove the remains of such a solution from the surface of the denture.

Another disadvantage of the known means is that it does not ensure the presence in its composition of only soluble substances. Therefore, the tablet includes insoluble ingredients, including chalk. Pieces of chalk settle on the surface of the denture and pollute it.

In this regard, the tool does not provide a wide scope, high speed, efficiency, accuracy, safety and uniformity of cleaning and bleaching of the denture.

Known antiseptic agent, which is a cold aqueous solution containing 2.7-3.3% hydrogen peroxide and 0.05% antifebrin, prepared by diluting perhydrol or hydrogen peroxide solution with water (State Pharmacopoeia of the USSR. Xth ed., Moscow: Medicine, 1968 p. 630-631).

The specified antiseptic agent has a low speed and effectiveness when cleaning dentures. The fact is that the product does not have a temperature of 37-42 ° C, therefore it does not provide hyperthermic softening of plaque, blood stains and pus. In addition, the tool does not have the optimal value of alkalinity and alkaline buffering, therefore, does not provide high penetrating, saponifying and washing activity. When a denture is lowered into this solution, oxygen gas bubbles form late, with low intensity and small size. Therefore, when they ascend, they do not provide effective mechanical upward movement of viscous and dense biological masses of loose plaque due to the insufficient intensity of their flow (flotation).

The presence of antifebrin reduces the safety of the solution due to the high toxicity of this aniline derivative. At the same time, the cool state of the product lowers the temperature regime in biological tissues, which also reduces its effectiveness and safety, since hypothermia increases the viscosity of colloidal fluids, complicates their removal and slows down the speed of chemical processes. In addition, the disadvantage of the drug is pronounced hypoosmotic activity, since the osmotic activity of the specified hydrogen peroxide solution is about 4 mOsm / l of water, which is significantly lower than the corresponding level of isoosmosis (280-290 mOsm / l of water) of human blood plasma is normal. A hypoosmotic solution promotes hydration of tissues and their swelling. Cells swell under the influence of a hypoosmotic solution, tissues swell. Therefore, the introduction of such a solution into the oral cavity leads to aggravation of edema of inflamed tissues, enhances the diffusion of water from the cavity into the tissues, weakens their barrier function by increasing edema of the cells, and creates the prerequisites for the generalization of infection.

Known cold antiseptic, carbonated with carbon dioxide, containing 3 ± 0.3% hydrogen peroxide, 2.0-10.0 sodium chloride and water, in the following ratios of components, mass. %:

Hydrogen peroxide 2.7-3.3 Sodium chloride 2.0-10.0 Carbon dioxide to create an overpressure of 0.2 atm at 8 ° C Water rest

(RU 2331441).

The disadvantage is the narrow scope, low speed, efficiency and safety, since it does not have a temperature of 37-42 ° C, does not have alkalinity, does not contain oxygen gas under excessive pressure, but contains up to 10% sodium chloride. Therefore, due to the lack of oxygen gas under excessive pressure, it does not provide an effective deodorizing and oxidizing effect. The lack of sufficient alkalinity does not provide an effective thinning, dissolving and whitening effect on plaque, traces of pus and blood. And the presence of 2-10% sodium chloride gives the solution an aggressive effect on the materials from which the denture can be made, and on the cells of the oral mucosa. The consequence of this effect can be erosion of the surface of the denture and local inflammation of the soft tissues of the oral cavity.

The objective of the invention is to expand the scope, increasing speed, efficiency, accuracy and safety due to the warm aqueous solution of hydrogen peroxide, sodium bicarbonate and oxygen gas.

The technical result is a whitening cleaning of the denture due to hyperthermic softening, alkaline saponification, oxidative whitening, cavitation loosening, flotation and suspension.

This goal is achieved due to a hypertonic alkaline cavitating solution of a whitening, surface-active substance heated to 37-42 ° С, rapidly diffusing into the thickness of dental plaque, blood stains and pus clots, which destroys interprotein and protein-lipid bonds in them, transforming hemoglobin and its residues into a soluble form, discoloring the remnants of blood and pus, removing them from the surface of the denture without aggressive action on its surface and mucous membranes of the oral cavity.

The essence of the proposed whitening denture cleaner is characterized in that it at a temperature of 37-42 ° C includes sodium bicarbonate, hydrogen peroxide, oxygen gas and water for injection in the following ratio of these components, mass. %:

Sodium bicarbonate 2.0-10.0 Hydrogen peroxide 3 ± 0.3 Oxygen to create an overpressure of 0.2 atm at 8 ° C Water for injections rest

The fact is that at a temperature of 37-42 ° C a solution prepared on the basis of water for injection, which is 2-10% sodium bicarbonate and 3 ± 0.3% hydrogen peroxide and containing oxygen gas until an overpressure of 0.2 atm is created (atmospheres) at 8 ° C, is an effective denture cleaner, ready to use. Moreover, it is an aqueous alkaline solution with oxidizing, saponifying, loosening, dissolving, bleaching, washing and pronounced penetrating ability, providing rapid hyperthermic softening of plaque, blood clots and pus, their dissolution and bleaching, rapid diffusion, physico-chemical and interstitial cavitation loosening, chemical (oxidative) discoloration and flotation removal of organic matter while washing and bleaching the surface of the denture. Moreover, the use of the solution at a temperature of 37-42 ° C provides an increase in the efficiency and safety of the denture cleaning process due to hyperthermia, which accelerates and enhances cleaning due to the temperature dependence of the rate of chemical, physicochemical and biochemical reactions according to the Arrhenius law. The selected temperature range is optimal, since normal tissue temperature in the oral cavity is below 37 ° C, and a temperature increase above 42 ° C is dangerous, since such hyperthermia can be excessively high and can cause temperature burns of the oral mucosa.

The use of water for injection as a solvent ensures the high quality of the cleaner, standardizes the physicochemical properties of the “working solution” and the factors of local interaction of the cleaner with the surface of the denture.

With the introduction of a whitening denture cleaner in a container or in the oral cavity, the claimed agent provides the formation of oxygen gas bubbles, which are in solution under excessive pressure, and oxygen gas bubbles generated from hydrogen peroxide as a result of a catalase reaction. Moreover, oxygen gas bubbles are the first to form due to a decrease in pressure in the solution after depressurization of the container in which the purifier is stored. In this regard, the process of gas bubble formation (cavitation) does not depend on the quantity and quality of biological tissues interacting with hydrogen peroxide, occurs at the same rate regardless of their presence, and is much more intensive than the release of molecular oxygen from hydrogen peroxide, which depends on catalase activity. Therefore, the introduction of the claimed cleaner into the oral cavity or container is immediately accompanied by intensive formation of oxygen gas bubbles and effective flotation, which mixes the solution and provides intensive and uniform physico-chemical interaction with the entire surface of the denture and plaque. That is why the cleaner removes liquid, viscous and dense biological masses from all parts of the denture. That is, this solution creates better conditions for the mechanical cleaning of dentures with simultaneous disinfecting and deodorizing effects. Some time after this, molecular oxygen begins to be released, which is formed by the interaction of hydrogen peroxide with the remains of rotting food, pus, blood and all plaque. In this regard, oxygen generated as a result of the catalase reaction from hydrogen peroxide is rationally used under these conditions to deodorize and inactivate those biological tissues that could not be inactivated and removed prior to the catalase reaction. Therefore, the claimed cleaner improves the speed, efficiency, safety of cleaning dentures and expands the scope.

Increasing the aeration of the solution by introducing oxygen gas into it under excess pressure provides a high speed and efficiency of cleaning the denture. The fact is that the introduction of oxygen into the claimed agent before creating an excess pressure of 0.2 atm (atmospheres) in the solution at 8 ° C allows for potential cavitation due to the formation of oxygen gas bubbles when pouring the solution (cleaner) from the container in which it is stored . Moreover, the selected excess pressure values allow to achieve the most intense formation of oxygen gas bubbles in the solution (cavitation) in the entire liquid volume, but exclude excessively boiling and splashing out of the spray outside the “working” chamber (capacity or oral cavity).

The rapidly advancing cold boiling of the entire volume of the solution gives each of its microvolumes good cleaning and deodorizing properties due to cavitation and flotation with simultaneous oxidizing activity. Therefore, such a solution, due to the rapid formation of oxygen gas bubbles and their ascent upward, immediately begins to mix, disinfect, deodorize and enter into physical and chemical interaction with plaque and other organic matter (in particular, blood, pus and saliva). In addition, the cold boiling of the solution provides the removal process due to flotation of pieces (fragments) of plaque, blood and pus from the surface of the denture. In addition, the solution enriched with oxygen has a pronounced oxidizing and deodorizing effect, which gives it a disinfecting activity. In particular, it provides the ability to eliminate the foul odor emanating from plaque and pus. Excessive oxygen gas pressure of 0.2 atm at 8 ° C provides sufficient safety for the consumer during storage and use of the purifier.

The presence in the purifier of sodium bicarbonate at a concentration of 2-10% provides the solution with alkaline buffering, alkaline activity and hypertonic activity due to pH 8.4 and osmotic pressure in the range of 280-1900 mOsmol / l of water. At the same time, the use of sodium bicarbonate at a concentration of 2% and above provides a reliable increase in the osmotic activity above 280 mOsmol / l of water while maintaining stable alkalinity at pH 8.4 due to the buffering properties of sodium bicarbonate. Giving the solution hypertonic activity is necessary to give the cleaner antiseptic and dehydrating activity, which increases the disinfecting effect of the cleaner and prevents its absorption by the oral mucosa before and after interaction with biological masses. The hypertonic and alkaline activity of the cleaner provides reliable and effective softening of plaque, blood clots and pus and the separation of their particles from the main biological mass and from the surface of the denture without excessive alkalization and without damaging alkaline hydrolysis of living tissues. The use of sodium bicarbonate at a concentration of up to 10.0% is explained, on the one hand, by the limit of the actually possible increase in its concentration by creating a saturated aqueous solution in the presence of hydrogen peroxide at room temperature, and on the other hand, by the absence of the local damaging effect of the saturated sodium bicarbonate solution due to for limitations of alkalinity within pH 8.4 due to the buffering properties of sodium bicarbonate. In this case, the optimal alkaline properties provide chemical saponification of these masses at the interface between the media and the diffusion penetration of the solution into the biological masses without damaging the material from which the denture is made and living tissues surrounding the denture in the oral cavity.

The presence in the purifier of hydrogen peroxide in a concentration of 3 ± 0.3% ensures high speed and efficiency of dissolution and discoloration of blood stains, thick and sticky pus and plaque due to saponifying, destructive, cavitation, flotation and suspension action in the presence of biological masses containing catalase . The presence of hydrogen peroxide provides interstitial release of molecular oxygen, the formation of gas bubbles (cavitation) in the entire volume, as well as in the thickness of dental plaque while destroying the "monolithic" structure of the biological mass due to interstitial cold boiling with the formation of oxygen gas bubbles. In this case, adhesion of vesicles with loosened and crushed particles of these masses occurs, these particles are detached from the surface of the denture due to bubbling (flotation) and the solution is mixed with diluted and crushed particles of biological masses. All this increases the effectiveness of cleaning the denture.

The proposed composition of the ingredients and the ratio of their concentration in the claimed cleaner at a temperature of 37-42 ° C are optimal for cleaning a denture by placing the prosthesis in the claimed solution, or in the bath of a device that is an ultrasonic cleaner, and / or when the prosthesis is irrigated with this solution, for example using an oral irrigator. The fact is that such a composition provides express softening, loosening of biological masses (plaque with fragments of saliva, blood and pus) on the surface of the denture, dissolving and whitening it without coloring and aggressive action on the surface of the denture and oral mucosa and without their burns.

The whitening denture cleaner can be poured into the capacity of an ultrasonic cleaner with a removable denture placed in it, with another similar removable dental structure, or with surgical instruments placed and left in it for 5-15 minutes, or can be used to irrigate the denture in oral cavity using an irrigator. In both cases, the claimed rinse aid provides rapid loosening, dissolution, whitening and removal of plaque, traces of pus and blood due to saponification, oxidation and cavitation destruction at the interface between the media through optimal alkalinity and gas aeration with oxygen, effective physico-chemical loosening during interstitial cavitation interstitial "boiling" of the solution during diffusion of the solution, dissolution and bleaching of the masses, as well as due to the saponification of biological masses with an alkaline agent loosening biomass interstitial boiling in the presence of catalase. Due to adhesion with plaque particles, emerging gas bubbles lift them up when floating in solution. Due to the continuous formation of oxygen gas bubbles and flotation, dispersion of the diluted plaque mass and suspension of the solution is ensured. Moreover, the intensity of the process of gas formation of molecular oxygen from hydrogen peroxide is determined by the activity of catalases, which are contained in a significant amount precisely in biological masses containing traces of blood and pus, or seeded with microorganisms and decomposing as a result of decay. Therefore, gas generation occurs in the layer of interfacial interaction of two media: a liquid cleaner and dense plaque. Molecular oxygen in these conditions is rationally used to destroy the dense mass of plaque, since the tool provides interstitial "boiling". In addition, oxygen is also rationally used for flotation of softened plaque particles, dispersion and suspension of media.

The ability of an aqueous solution of hydrogen peroxide and sodium bicarbonate to dissolve and bleach thick pus and dried blood with local interaction was described by us earlier [1-5].

Therefore, this tool expands the scope of application, creates optimal conditions for safe quick and effective loosening, thinning, dissolution, disinfection and whitening of plaque, without local inflammation of the soft tissues of the oral cavity. Therefore, it increases the speed, efficiency of cleaning dentures, reduces the likelihood of their destruction, prolongs the period of their wearing, reduces the frequency of replacement of wearable dentures with new dentures.

We have conducted a study of the scope, speed, effectiveness and safety of the claimed funds in model conditions when cleaning dentures and surgical tweezers artificially stained with donor blood. For this, we used defective full dentures of the upper jaw with metal arches and a base with artificial ceramic teeth, and surgical tweezers that were completely covered with donor blood from all sides and then placed in a dry, warm place for a day (at 37 ° C) . A day later, dentures and tweezers looked stained with blood, which in the form of a dried crust covered their surface with an uneven layer, having a brown color. In parallel with this, 500 ml glass baths were prepared, providing free placement of dentures, tweezers and the required volume of “working solution” in them.

To prepare the working solution was used tap water (control), an aqueous solution of coreg tablets (reference drug) and the claimed whitening cleaner for dentures.

At the same time, Korega ^® tablets (30 tablets per pack) were used as a prototype and analogues (simultaneously) - (Manufacturer: Stafford Miller (Ireland) Ltd., Clocherane, Youghal Road, Dungarvan, Co. Waterford, Ireland), series : 6U9E (Produced: 06/2016, valid until: 05/2019). The fact is that the composition for cleaning dentures containing bleach in the form of an inorganic persal selected from alkali metal persulfates, alkali metal perborates and mixtures thereof, a rapidly emitting gas generator, which is an effervescent pair of (bi) carbonate acid, and 0, 01% -25%, demethicone copolyol selected from alkyl- and alkoxydimethicone copolyols having a specific formula, is presented on the international market in the form of several options for compressed tablets that differ in name but are identical the specified composition.

Then 3 series of laboratory experiments were carried out (5 experiments in each series).

In the first series, 250 ml of tap water with a temperature of 25 ° C was poured into the tank.

In the second series, 250 ml of tap water was poured into the tank at a temperature of 25 ° C, into which one Korega tablet was dropped, having a temperature of 25 ° C.

In the third series, 250 ml of a solution of 2.0% sodium bicarbonate, 2.7% hydrogen peroxide and oxygen gas at a pressure of 0.2 atm at 8 ° C, prepared in water for injection and heated to a temperature of 37 ° were poured into the tank FROM.

Then, in each container, one denture and tweezers stained with dried blood were recessed in the “working solution”. After this, time was noted and the state of the working solution and the dynamics of the color of the surface of the dentures and tweezers were monitored for 30 minutes.

The following results were obtained.

In the first series of experiments, 30 minutes after being placed in the tap water, all 5 dentures and tweezers remained covered with a brown film. At the same time, the water in which the dentures and tweezers were recessed became a light brown-red color.

In the second series of experiments in all 5 containers, the water immediately began to “boil” after placing the tablets in it and after 3-5 seconds turned blue. In this case, the rapid formation of gas bubbles and "cold boiling" lasted about a minute, after which it stopped completely. Moreover, in all 5 containers, the surface of the water was covered with a layer of white-blue foam. The foam melted very slowly and remained virtually unchanged, and the solution remained blue until the end of the study. After 30 minutes of finding dentures and tweezers in a cold blue solution, all 5 dentures and tweezers remained covered with a brown film. The working solution turned a little brown. At the bottom of each container, insoluble particles of white material were found that resembled small pieces of chalk.

In the third series of experiments in all 5 containers, the solution immediately began to “boil” after placing dentures and tweezers in it, and the surface of the solution began to become covered with white foam. At the same time, after 5-7 seconds in all containers, the surface was completely covered with a white “cap” of foam. At the same time, the surface of all prostheses and tweezers began to lose red-brown color, after 17-26 seconds the surface of prostheses and tweezers became white-light brown, and after 2-3 minutes the surfaces of all prostheses and tweezers became completely clean, not had a plaque of blood. The surface of dentures and tweezers looked clean, bleached and had no signs of damage. In this case, the solution itself became cloudy and acquired a light brown color.

Therefore, cold tap water and a cold solution obtained by dissolving cold Korega tablet tablets in cold water from a tap are not cleaned and do not bleach after 5-15 minutes of interaction dentures and tweezers stained with clotted and dried blood. At the same time, a warm solution of 2.0% sodium bicarbonate, 2.7% hydrogen peroxide and oxygen gas prepared at water for injection at an overpressure of 0.2 atm at 8 ° C loosens, dissolves, discolors and removes coagulated blood from the surface dentures and surgical instruments, whitens them 3 minutes after the start of interaction.

Therefore, the claimed whitening denture cleaner, characterized in that at a temperature of 37-42 ° C, it is a solution of 2.0-10.0% sodium bicarbonate and 3 ± 0.3% hydrogen peroxide, aerated with oxygen gas to create excess pressure 0.2 atm at 8 ° C, and the solvent is water for injection, which provides quick and effective softening, loosening, dissolving, bleaching and removing traces of blood from the treated surface without mechanical and physico-chemical damage to the prosthesis and mucous membrane oral cavity, therefore, expands the scope, increases the speed, efficiency, accuracy and safety of cleaning dentures.

Thus, a warm oxygenated water solution of hydrogen peroxide and sodium bicarbonate quickly softens the thick coating of blood and pus, diffuses into biological masses, loosens, dissolves, discolors and removes them from the surface of dentures, other dental structures and surgical instruments.

The invention provides an expansion of the scope, increasing speed, efficiency, accuracy and safety due to local hyperthermic softening, alkaline saponification, cavitation loosening, flotation removal and oxidative whitening of plaque in the form of blood and pus.

Literature

1. Urakov A.L., Nikityuk D.B. Solvents of pus. New drugs for the treatment of purulent diseases. The successes of modern science. 2015. No1. S. 1096-1101.

2. Urakov A.L., Urakova N.A., Urakova T.V. A new group of drugs: pus solvents. International Journal of Applied and Basic Research. 2016. No. 6 (part 5). S. 881-884.

3. Urakov A.L., Urakova N.A., Urakova T.V. New medicines invented - bruising bleaches. International Journal of Applied and Basic Research. 2016. No. 6 (part 5). S. 878-881.

4. Urakova N.A., Gadelshiina A.A. A new medicine has been invented - a baking powder of dried blood, which ensures the soaking of bandages adhered to the wound. International Journal of Applied and Basic Research. 2016. No. 11-3. S. 464-467.

5. Urakov A., Urakova N., Reshetnikov A., Kopylov M., Chernova L. Solvents of pus-medicines with physical-chemical aggressive action. IOP Conf. Series: Journal of Physics: Conf. Series. 2017. V. 790. 012033. doi: 10.1088 / 1742-6596 / 790/1/01203.

Claims (3)

A whitening denture cleaner, characterized in that it includes sodium bicarbonate, hydrogen peroxide, oxygen gas and water for injection in the following ratio of these components, mass. %: Sodium bicarbonate 2.0-10.0 Hydrogen peroxide 3 ± 0.3 Oxygen to create an overpressure of 0.2 atm at 8 ° C Water for injections rest and heated to a temperature of 37-42 ° C.