CN105248449B - A kind of toothbrush cleansing tablet and preparation method thereof, application method - Google Patents
A kind of toothbrush cleansing tablet and preparation method thereof, application method Download PDFInfo
- Publication number
- CN105248449B CN105248449B CN201510660614.7A CN201510660614A CN105248449B CN 105248449 B CN105248449 B CN 105248449B CN 201510660614 A CN201510660614 A CN 201510660614A CN 105248449 B CN105248449 B CN 105248449B
- Authority
- CN
- China
- Prior art keywords
- toothbrush
- tablet
- acid
- mass fraction
- cleansing tablet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Cosmetics (AREA)
- Detergent Compositions (AREA)
Abstract
The invention discloses a kind of toothbrush cleansing tablet and preparation method thereof, application method, it is povidone/dioxygen aquo complex that the toothbrush cleansing tablet, which includes oxygen evolution agent, basic carbonate raw material, acid material, additive of tablet, peppermint or lemon extract and food coloring, the oxygen evolution agent,.The toothbrush cleaning piece preparation method processing step be：（A）Acid material, lubricant are added to mix in mixer and ground；（B）Continuously add carbonate and/or bicarbonate makees basic carbonate raw material, continue mixing and grind；（C）Then oxygen evolution agent, lubricant, peppermint or lemon extract, food coloring are added, is uniformly mixing to obtain powder；（D）By the rotated tabletting machine of powder, up to toothbrush sanitizing effervescent tablet.In use, effervescent tablet is turned to aqueous solution, by toothbrush immersion in aqueous, take out rinse airing after ten minutes.The toothbrush cleansing tablet of the present invention carries out sterilization to toothbrush, for ensureing that people's health has very major and immediate significance.
Description
Technical field
The present invention relates to toothbrush and other rinse apparatus and the disinfection technical field of shallow contact daily necessities, especially
It is related to a kind of toothbrush cleansing tablet and preparation method thereof, application method.
Background technology
There has been no clean what is used dedicated for toothbrush in conventional detergents.The composition of common detergent is lived including surface
The components such as property agent, sodium carbonate, bleaching powder.The bactericidal effect of this detergent is very weak and sterilization flora is single, is not suitable as pair
The direct substitute of toothbrush cleaning-sterilizing.Especially for the various protozoons often retained on toothbrush（Amoeba meleagridis, ox
Own trichomonad, balantidium coli, flagellate etc.）And various bacteriums（Downright bad ash oxygen screw bacterium, Clostridium, grape of being sick of
Coccus, intestines vibrios, treponema bacterium etc.）/（Coccus, Bacillus acidi lactici, bacillus and conveyor screw, wherein Bacillus acidi lactici occupy very
Big ratio (about 30~40%)）Killing effect it is poor.
Medicine clinical research demonstrates the number of bacteria retained on the toothbrush using 1~2 week and may be up to hundreds of thousands, its
In many bacteriums be hazardous to the human body effect.Such as Bacillus acidi lactici can make to remain in the swill hair in dental surface and teeth space
Ferment production acid, the enamel acid corrosion of dental surface and soften, turn yellow so that defect and form carious tooth；
Dentist is detected the used toothbrush of people, it is found that it is a large amount of white new toothbrush just had using only 3~4 weeks
Color reads the breeding of the various pathogens such as coccus, Streptococcus mutans, hemolytic streptococcus, pneumobacillus, staphylococcus, these bacterium energy
Directly invade mucous membrane of mouth.
The process toothbrush of brushing teeth is highly susceptible to pollute, including the microorganism in oral cavity source, as dental caries pathogenic bacteria~
Streptococcus mutans, Periodontal Pathogens, Candida albicans, also including some non-oral microorganisms, such as some enteric bacteria, also from
Pseudomonas is isolated in used toothbrush.Research shows that cariogenic bacteria and Periodontal Pathogens can be by reusing dirt
The toothbrush of dye and travel to another position from a position in oral cavity.And after patient replaces contaminated toothbrush, oral cavity disease
Disease can all be eased such as lichen planus, mouth syndrome of burning.This explanation control toothbrush pollution can effectively reduce oral cavity and infect again
Probability.Therefore toothbrush can regard a potential source of infection as, be possible to cause when collective resistance declines oral cavity and
Whole body system infects.And have the crowd of systemic disease for some, such as diabetic and cardiac valves patient and immune
Handicapped, further increases it using the serious toothbrush of microbial contamination and infects probability.The sterilization of toothbrush as can be seen here, prevents
Microorganism multiplies breeding on toothbrush, and the health for ensureing human oral cavity and body other systems is very significant and non-
It is often necessary.
Bacterium on toothbrush is mainly derived from oral cavity and air.One side human oral cavity is ring existing for a various bacteria
Border, part bacterium is not washed away and remain on toothbrush after brushing teeth, and on the other hand, toothbrush is typically exposed to air after
In so that toothbrush has the chance contacted with the bacterium in air.And toothbrush is often placed in the dark moist place of washing room, disease
Bacterium is easier to grow breeding.Unclean toothbrush is probably the infection sources of a variety of diseases, because these bacteriums can deposit when brushing teeth
Stay in the every nook and cranny gap in tooth and oral cavity, can be by directly swallowing or damaged mucous membrane of mouth and cavity invade human body
Give rise to diseases, it is seen that the sterilization of toothbrush, the sanitation and hygiene for keeping toothbrush are critically important, it is therefore necessary to are taken measures
To reduce or eliminate these harmful bacterias.
The content of the invention
The purpose of the present invention is in view of the above-mentioned defects in the prior art, there is provided a kind of toothbrush cleansing tablet and preparation method thereof,
Application method, makees oxygen evolution agent using povidone/dioxygen aquo complex, be equipped with basic carbonate raw material, additive of tablet, peppermint or
Lemon extract, food coloring are made that performance is stable, the sterilized disinfection tablet of toothbrush easy to use.Sterilizing is carried out to toothbrush to disappear
Poison, for ensureing that people's health has very major and immediate significance.In addition to the cleaning available for toothbrush, it can also use
In the sterilization of other rinse utensils.
To achieve these goals, the technical scheme is that：
A kind of toothbrush cleansing tablet, the toothbrush cleansing tablet is as made by povidone/dioxygen aquo complex makees oxygen evolution agent
Effervescent tablet.
Preferably, the toothbrush cleansing tablet is used for the sterilization of toothbrush.
Preferably, the toothbrush cleansing tablet is used for the sterilization of rinse apparatus.
Preferably, the toothbrush cleansing tablet is used for the sterilization of the shallow contact daily necessities of toothbrush.
Preferably, the effervescent tablet include oxygen evolution agent, basic carbonate raw material, acid material, additive of tablet,
Peppermint or lemon extract and food coloring, the oxygen evolution agent are povidone/dioxygen aquo complex.
Preferably, the mass fraction of the povidone/dioxygen aquo complex is 0.1~10.
Preferably, the toothbrush cleansing tablet further includes basic carbonate raw material, and the basic carbonate raw material is
Carbonate and/or bicarbonate.
Preferably, the mass fraction of the carbonate and/or bicarbonate is 0.5~30.
Preferably, the one kind or more of the acid material in citric acid, malic acid, tartaric acid, fumaric acid
The mixture of kind, the mass fraction of the acid material is 1.0~20.
Preferably, the mass fraction of the additive of tablet is 1~20；The additive of tablet includes adhesive and profit
Lubrication prescription, described adhesive are polyvinylpyrrolidone, and the lubricant is superfine silica gel powder or talcum powder.
Preferably, the mass fraction of the Mint Essence is 0.01~1.0.
Preferably, the food coloring for light blue, ciba blue 2b, indigo carmine, indigo blue potassium, it is indigo,
Indigo two potassium sulfate salt, thioindigo, indigo naturalis color food coloring, the mass fraction of the food coloring is 0.01~1.0.
The present invention simultaneously provides the preparation method of above-mentioned toothbrush cleansing tablet, and the processing step of the preparation method is：
（A）Lubricant in acid material, additive of tablet is added to mix in mixer and is ground；
（B）Continuously add carbonate and/or bicarbonate makees basic carbonate raw material, continue mixing and grind；
（C）Then oxygen evolution agent, the lubricant of additive of tablet, peppermint or lemon extract, food coloring are added, stirring is equal
Uniformly mixed powder that is even, obtaining；
（D）By step（C）The obtained rotated tabletting machine of uniformly mixed powder, steeps up to the toothbrush sanitizing
Rise piece.
Invention additionally provides the application method that above-mentioned toothbrush cleansing tablet is applied as disinfectant detergent, toothbrush cleaning
The application method of piece is：
（A）Take a piece of toothbrush cleansing tablet, toothbrush cleansing tablet be put into about 100ml water into the water, in acid material and
Under basic carbonate raw material collective effect, a large amount of bubbles are produced（Carbon dioxide）, make toothbrush cleansing tablet disintegration and thawing rapidly, shape
Into effervesce aqueous solution；
（B）Toothbrush or other rinse utensils and shallow contact daily necessities are immersed in effervesce aqueous solution 5-10 minutes；
（C）Take out, naturally dry after being rinsed with tap water.
Dimension ketone be in vain universal love newly increase income company production product, it is polyvinylpyrrolidone and H2O2Complex compound；Outside
Sight is white powder, in solid form existing H2O2Content is 16-20%（Include more than 20% hydrogen peroxide w/w）, dry
It can stablize under dry state and preserve the several years, water and other organic solvents can be dissolved in, persistently released with that can stablize when water, saliva contacts
Release H2O2, i.e., H certain in solution is kept within the regular hour2O2Concentration, it is thus possible to substantially increase H2O2Sterilizing
Effect.Be it is safe, stablize and also be H2O2.These products, which meet water, can then discharge H rapidly2O2。
It is to be based on n-vinyl pyrrolidone in vain to tie up ketone（NVP）And H2O2Hydrogen bonding compound.Pyrrolidones, which is one, acyl
Five membered lactams rings of amine carbonyl, amidocarbonylation is a strong hydrogen bond acceptor, and H2O2It is a strong hydrogen bond
Supplier, then it will form a stable complex compound with pyrrolidones.Through nuclear magnetic resonance（NMR）Detection shows, solid carbon
13 there is a kind of crucial bottom offset in carbonyl carbon, it was demonstrated that H2O2There are network and effect between PVP.When complex compound is in water
When being contacted in solution with excessive water, the H of hydrogen bond one end on complex compound2O2Just it is replaced by water, therefore H2O2Just it is released.
With simple compound H2O2Unlike solution, the H of release during complex compound dimension ketone is white2O2Concentration when it is limited
, only when 1）Complex solution further dilutes, and 2）Because of sterilization, blanching effect consumption part H2O2, dissociate in complex solution
H2O2Concentration it is relatively low when, can just discharge new free H in complex compound2O2；And as the H of separate out2O2Concentration reaches certain
During limit, it may be prevented from continuing to discharge.Most of H in complex solution2O2It is with PVP-H2O2/PVPP-H2O2The shape of polymer
Formula exists.This feature is to reducing H2O2The shortcomings that（Higher toxicity and irritation）There is highly significant, reduce to skin
Calcination or wound stimulation, using it is upper as mild as a dove.Therefore, dimension ketone is very safe that human body will not be formed and injured in vain
A kind of hydrogen peroxide product.
Go out H with sustained release can be stablized when water, saliva contacts since the dimension white product of ketone has2O2, there is provided the spy of active oxygen
Property, thus tie up the white PVP-H of ketone2O2Complex compound can be used as oxygen evolution agent, be produced suitable for oral cavity whitening care product, disinfection nursing
Product, can have the characteristic that sterilizing, decontamination brighten to act on as effective calculus removal agent/bleaching agent in toothwash tablet.
The most significant feature of product is exactly H2O2It is in complex pattern with polyvinylpyrrolidone, by poly- second under dry powder
The complex protection effect of alkene pyrrolidone, can effectively keep H2O2Complexing stablize, extend H2O2Stable period；And when chance
During to water, saliva, by the good hydrophilic dissolubility of polyvinylpyrrolidone, the H of complexing2O2Continuously it is discharged into solution
In, if the H in solution2O2Concentration increases, H2O2The speed of complexing release can slow down, and stablize release in certain time so as to reach
Purpose, maintain H2O2Solution concentration, extend H2O2The action time of sterilizing, increases H2O2The effect effect of sterilizing
Fruit.
And simple H2O2, stability is poor, H under long-time storage2O2Concentration can reduce；H during use2O2Concentration just becomes quickly
Must be very big, and reduce rapidly, H2O2The continuous action time is very short, and not only the effect of sterilizing can reduce quickly, but also high concentration
H2O2Some human body side effects can also be caused.
Other sterilizing objects, use peroxide salts substances, such as SODIUM PERCARBONATE, sodium peroxydisulfate, sodium perborate more, this
A little materials discharge rapidly H when being all dissolving2O2, the H in a period of time can not be kept2O2Concentration is stablized, thus to meet that sterilization disappears
Poison is needed, it is necessary to increase the proportion scale of peroxide so that uses H in solution when starting2O2It is dense, easily lead
Cause human body side effect.
The present invention mechanism be：When effervescent tablet into the water after, effervescent tablet meet water react, in acid material and alkali
Under acid carbonate raw material collective effect, a large amount of bubbles are produced（Carbon dioxide）, tablet is disintegrated and is melted rapidly, during tablet disintegration
In effervesce shape, tablet rolling up and down in water can be made by being disintegrated the bubble of generation, accelerate it to be disintegrated and melt.Oxygen evolution agent gathers dimension
Ketone/dioxygen aquo complex（It is white to tie up ketone）, it can in effervescent tablet aqueous solution sustained release oxonium ion, have Continuous sterilization disinfection
Function, have strong suppression and killing effect for various protozoons and bacterium, continue broad-spectrum sterilization, and free from extraneous odour, without cause
Cancer, without teratogenesis the problems such as, revolutionize existing all purpose cleaner bactericidal effect it is poor, sterilization flora it is single, be not suitable for using
In the clean present situation of toothbrush.
Take this product to be put into formation effervesce aqueous solution in about 100ml water during use, toothbrush is immersed in 5- in effervesce aqueous solution
10 minutes, naturally dry can reach the effect of toothbrush sanitizing sterilizing after being rinsed with tap water.Preparation process of the present invention is easy easily
OK, it is easy to use, there is strong, the safe and non-toxic, steady performance that sterilizes, toothbrush remaining bacteria is killed up to 100%, it is non-
Often the toothbrush sanitizing sterilizing in suitable daily life uses, it can also be used to which other rinse apparatus and shallow contact daily necessities disappear
Kill bacterium.Oxygen evolution agent povidone/dioxygen aquo complex (the dimension ketone never used in formula by adding conventional detergents
In vain) so that the detergent has more preferable toothbrush cleaning effect.
This disinfectant can also be used for the disinfection of other shallow contact daily necessitiess.
It is the sterilizing experimental data table of the present invention below
Embodiment
The present invention is further described with reference to specific embodiment.
Embodiment 1
（A）One or more mixtures in selection citric acid, malic acid, tartaric acid, fumaric acid make acid material, institute
The mass fraction for stating acid material is 1.0；Selection polyvinylpyrrolidone makees adhesive, selects superfine silica gel powder or talcum powder to make to moisten
As additive of tablet, the mass fraction of additive of tablet is 1 for lubrication prescription, adhesive and lubricant；
Lubricant in acid material, additive of tablet is added to mix in mixer and is ground；
（B）Continuously add carbonate or bicarbonate makees basic carbonate raw material, the mass fraction of basic carbonate raw material
Continue mixing for 0.5 to grind；
（C）Then oxygen evolution agent povidone/dioxygen aquo complex, mass fraction 0.1, the lubrication of additive of tablet are added
Agent, peppermint or lemon extract, food coloring, stir evenly, mixing 100 mesh of sieving, obtained uniformly mixed powder；
Food coloring is light blue, ciba blue 2b, indigo carmine, indigo blue potassium, indigo, indigo two potassium sulfate salt, sulphur
For indigo, indigo naturalis color food coloring, the mass fraction of the food coloring is 0.01；
（D）By step（C）The obtained rotated tabletting machine of uniformly mixed powder, compression force 15-20KN, piece diameter
For 22mm, hardness 60-80N, up to the toothbrush sanitizing effervescent tablet.
The toothbrush cleansing tablet is as the application method that disinfectant detergent is applied：
（A）Take a piece of toothbrush cleansing tablet, toothbrush cleansing tablet be put into about 100ml water into the water, in acid material and
Under basic carbonate raw material collective effect, a large amount of bubbles are produced（Carbon dioxide）, make toothbrush cleansing tablet disintegration and thawing rapidly, shape
Into effervesce aqueous solution；
（B）Toothbrush or other rinse utensils and shallow contact daily necessities are immersed in effervesce aqueous solution 5-10 minutes；
（C）Take out, naturally dry after being rinsed with tap water.
Embodiment 2
（A）One or more mixtures in selection citric acid, malic acid, tartaric acid, fumaric acid make acid material, institute
The mass fraction for stating acid material is 20；Selection polyvinylpyrrolidone makees adhesive, selects superfine silica gel powder or talcum powder to make to moisten
As additive of tablet, the mass fraction of additive of tablet is 20 for lubrication prescription, adhesive and lubricant；
Lubricant in acid material, additive of tablet is added to mix in mixer and is ground；
（B）Continuously add carbonate and bicarbonate makees basic carbonate raw material, the mass fraction of basic carbonate raw material
Continue mixing for 30 to grind；
（C）Then add oxygen evolution agent povidone/dioxygen aquo complex, mass fraction 10, additive of tablet lubricant,
Peppermint or lemon extract, food coloring, stir evenly, mixing 100 mesh of sieving, obtained uniformly mixed powder；
Food coloring is light blue, ciba blue 2b, indigo carmine, indigo blue potassium, indigo, indigo two potassium sulfate salt, sulphur
For indigo, indigo naturalis color food coloring, the mass fraction of the food coloring is 1.0；
（D）By step（C）The obtained rotated tabletting machine of uniformly mixed powder, compression force 18-20KN, piece diameter
For 22mm, hardness 60-90N, up to the toothbrush sanitizing effervescent tablet.
Embodiment 3
（A）One or more mixtures in selection citric acid, malic acid, tartaric acid, fumaric acid make acid material, institute
The mass fraction for stating acid material is 10；Selection polyvinylpyrrolidone makees adhesive, selects superfine silica gel powder or talcum powder to make to moisten
As additive of tablet, the mass fraction of additive of tablet is 10 for lubrication prescription, adhesive and lubricant；
Lubricant in acid material, additive of tablet is added to mix in mixer and is ground；
（B）Continuously add carbonate and/or bicarbonate makees basic carbonate raw material, the mass parts of basic carbonate raw material
Number continues mixing for 15 and grinds；
（C）Then add oxygen evolution agent povidone/dioxygen aquo complex, mass fraction 5, additive of tablet lubricant,
Peppermint or lemon extract, food coloring, stir evenly, mixing 100 mesh of sieving, obtained uniformly mixed powder；
Food coloring is light blue, ciba blue 2b, indigo carmine, indigo blue potassium, indigo, indigo two potassium sulfate salt, sulphur
For indigo, indigo naturalis color food coloring, the mass fraction of the food coloring is 0.5；
（D）By step（C）The obtained rotated tabletting machine of uniformly mixed powder, compression force 18-20KN, piece diameter
For 22mm, hardness 60-80N, up to the toothbrush sanitizing effervescent tablet.
The toothbrush cleansing tablet is as the application method that disinfectant detergent is applied：
（A）Take a piece of toothbrush cleansing tablet, toothbrush cleansing tablet be put into about 100ml water into the water, in acid material and
Under basic carbonate raw material collective effect, a large amount of bubbles are produced（Carbon dioxide）, make toothbrush cleansing tablet disintegration and thawing rapidly, shape
Into effervesce aqueous solution；
（B）Toothbrush or other rinse utensils and shallow contact daily necessities are immersed in effervesce aqueous solution 5-10 minutes；
（C）Take out, naturally dry after being rinsed with tap water.
The above is only one embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, without departing from the technical principles of the invention, some improvement can also be made, these improvement also should be regarded as this hair
Bright protection domain.
Claims (1)
- A kind of 1. application method that toothbrush cleansing tablet is applied as disinfectant detergent, it is characterised in that：（A）A piece of toothbrush cleansing tablet is taken, toothbrush cleansing tablet is put into 100ml water, in acid material and basic carbonate raw material Under collective effect, a large amount of bubbles are produced, makes toothbrush cleansing tablet disintegration and thawing rapidly, forms effervesce aqueous solution；（B）Toothbrush or other rinse utensils and shallow contact daily necessities are immersed in effervesce aqueous solution 5-10 minutes；（C）Take out, naturally dry after being rinsed with tap water；The toothbrush cleansing tablet is as the effervescent tablet made by povidone/dioxygen aquo complex makees oxygen evolution agent, povidone/dioxygen Aquo complex mass fraction is 0.1~10；The toothbrush cleansing tablet further includes following components：Basic carbonate raw material, the basic carbonate raw material are carbonate and/or bicarbonate；The carbonate and/or carbon The mass fraction of sour hydrogen salt is 0.5~30；Acid material, one or more mixing of the acid material in citric acid, malic acid, tartaric acid, fumaric acid Thing；The mass fraction of the acid material is 1.0~20；Additive of tablet, the additive of tablet include adhesive and lubricant, and described adhesive is polyvinylpyrrolidone, the profit Lubrication prescription is superfine silica gel powder or talcum powder；The mass fraction of the additive of tablet is 1~20；Mint Essence or lemon extract, the mass fraction of the Mint Essence or lemon extract is 0.01~1.0；Food coloring, the food coloring is light blue, ciba blue 2b, indigo carmine, indigo blue potassium, indigo, indigo two sulphur Acid potassium salt, thioindigo；The mass fraction of the food coloring is 0.01~1.0.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510660614.7A CN105248449B (en) | 2015-10-15 | 2015-10-15 | A kind of toothbrush cleansing tablet and preparation method thereof, application method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510660614.7A CN105248449B (en) | 2015-10-15 | 2015-10-15 | A kind of toothbrush cleansing tablet and preparation method thereof, application method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105248449A CN105248449A (en) | 2016-01-20 |
| CN105248449B true CN105248449B (en) | 2018-04-24 |
Family
ID=55088657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510660614.7A Active CN105248449B (en) | 2015-10-15 | 2015-10-15 | A kind of toothbrush cleansing tablet and preparation method thereof, application method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105248449B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111307931B (en) * | 2020-02-18 | 2022-08-30 | 广东省特种设备检测研究院珠海检测院 | Effervescent tablet containing magnetic powder and preparation method thereof |
| CN111257408B (en) * | 2020-02-18 | 2022-08-30 | 广东省特种设备检测研究院珠海检测院 | Effervescent tablet containing nano magnetic powder and application thereof |
| CN111690480A (en) * | 2020-06-23 | 2020-09-22 | 刘晓彤 | Anti-inflammation and sterilization traditional Chinese medicine toothbrush cleaning sheet |
| CN111748415B (en) * | 2020-07-24 | 2022-02-25 | 广州立白企业集团有限公司 | Toothbrush sterilizing and cleaning effervescent tablet and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202654429U (en) * | 2011-12-16 | 2013-01-09 | 上海高丰医疗电器有限公司 | Disinfecting tablet for false tooth brush |
| CN103918712A (en) * | 2014-04-20 | 2014-07-16 | 阎昭良 | Cleaning effervescent tablet for toilet things and tableware and preparation and application method thereof |
-
2015
- 2015-10-15 CN CN201510660614.7A patent/CN105248449B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202654429U (en) * | 2011-12-16 | 2013-01-09 | 上海高丰医疗电器有限公司 | Disinfecting tablet for false tooth brush |
| CN103918712A (en) * | 2014-04-20 | 2014-07-16 | 阎昭良 | Cleaning effervescent tablet for toilet things and tableware and preparation and application method thereof |
Non-Patent Citations (2)
| Title |
|---|
| PVP系聚合物和络合物在日化产品中的应用;袁国栋;《日用化学品科学》;20110430;第34卷(第4期);第40-41页 * |
| 用于口腔护理的两种新型聚合物———乙烯基甲醚/马来酸酐共聚物以及维酮白系列;王坚强;《牙膏工业》;20090831;第19卷;第63-64页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105248449A (en) | 2016-01-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Badaro et al. | Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser | |
| JP6956143B2 (en) | Antimicrobial composition and how to use it | |
| Shay | Denture hygiene: a review and update | |
| Levrini et al. | Scanning electron microscopy analysis of the growth of dental plaque on the surfaces of removable orthodontic aligners after the use of different cleaning methods | |
| US4792442A (en) | Method and composition for prevention and treatment of oral disease | |
| US4837009A (en) | Method and composition for prevention of plaque formation and plaque dependent diseases | |
| US4851213A (en) | Method and composition for prevention and treatment of oral disease due to S. Sanguis | |
| US4793989A (en) | Method and composition for prevention and treatment of oral disease | |
| CN105248449B (en) | A kind of toothbrush cleansing tablet and preparation method thereof, application method | |
| Neppelenbroek | The importance of daily removal of the denture biofilm for oral and systemic diseases prevention | |
| Montagner et al. | In vitro antifungal action of different substances over microwaved-cured acrylic resins | |
| JP2012509271A (en) | Dental instrument cleanser | |
| Gambin et al. | Antimicrobial activity of glycolic acid as a final irrigant solution for root canal preparation | |
| CN107693392B (en) | Toothpaste containing enzyme preparation and preparation method thereof | |
| Oussama et al. | Materials and methods for cleaning dentures--a review | |
| King et al. | Denture cleaning—best practice | |
| KR101344061B1 (en) | Composition for cleaning toothbrush | |
| Al-Jammali et al. | Causes and treatment of complete denture staining: A review | |
| Darout et al. | Survival rate of oral bacteria on toothbrush and Miswak stick | |
| Garg et al. | Denture hygiene, different strategies | |
| Duymuş et al. | Evaluation of methods of denture cleaning | |
| CN112438914A (en) | Denture cleaning tablet and preparation method thereof | |
| EP0461105B1 (en) | Composition for prevention of plaque formation and plaque dependent diseases | |
| CN103766398A (en) | Special cleaning liquid for toothbrush | |
| Jathar et al. | Comparative evaluation of various disinfectant agents to disinfect toothbrush microbiota |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: Zhongshan Road city of Jiaozuo province Henan 454450 fraternity County No. 9 pharmaceuticals Limited by Share Ltd Applicant after: The medical fraternity xinkaiyuan Technology Group Limited by Share Ltd Address before: Zhongshan Road city of Jiaozuo province Henan 454450 fraternity County No. 9 pharmaceuticals Limited by Share Ltd Applicant before: Boai New Kaiyuan Pharmaceutical Co., Ltd. |
|
| CB02 | Change of applicant information | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP02 | Change in the address of a patent holder |
Address after: 454450 No. 1888, Cultural Road (eastern section), Poai County, Jiaozuo, Henan Patentee after: The medical fraternity xinkaiyuan Technology Group Limited by Share Ltd Address before: 454450 Bo Ai new open source pharmaceutical Limited by Share Ltd, Pok AI County, Zhongshan Road, Henan 9, Limited by Share Ltd Patentee before: The medical fraternity xinkaiyuan Technology Group Limited by Share Ltd |
|
| CP02 | Change in the address of a patent holder | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220308 Address after: 454450 No. 1888, Cultural Road (eastern section), Poai County, Jiaozuo, Henan Patentee after: Boai Xinkaiyuan Pharmaceutical Co.,Ltd. Address before: 454450 No. 1888, Cultural Road (eastern section), Poai County, Jiaozuo, Henan Patentee before: BOAI NKY MEDICAL HOLDINGS Ltd. |
|
| TR01 | Transfer of patent right |