RU2579659C2 - Способ для применения в терапии - Google Patents
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- RU2579659C2 RU2579659C2 RU2011141889/10A RU2011141889A RU2579659C2 RU 2579659 C2 RU2579659 C2 RU 2579659C2 RU 2011141889/10 A RU2011141889/10 A RU 2011141889/10A RU 2011141889 A RU2011141889 A RU 2011141889A RU 2579659 C2 RU2579659 C2 RU 2579659C2
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6018—Lipids, e.g. in lipopeptides
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
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- Genetics & Genomics (AREA)
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- Toxicology (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Orthopedic Medicine & Surgery (AREA)
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Applications Claiming Priority (5)
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| US16116509P | 2009-03-18 | 2009-03-18 | |
| US61/161,165 | 2009-03-18 | ||
| US25602809P | 2009-10-29 | 2009-10-29 | |
| US61/256,028 | 2009-10-29 | ||
| PCT/EP2010/053519 WO2010106127A2 (en) | 2009-03-18 | 2010-03-18 | Method for therapeutic use |
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| RU2011141889A RU2011141889A (ru) | 2013-04-27 |
| RU2579659C2 true RU2579659C2 (ru) | 2016-04-10 |
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| UA107571C2 (xx) * | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
| CN106390107B (zh) * | 2009-06-10 | 2019-12-31 | 纽约大学 | 病理tau蛋白的免疫靶向 |
| AU2013205313B2 (en) * | 2010-10-07 | 2016-05-19 | Ac Immune S.A. | Phosphospecific antibodies recognising tau |
| MY164376A (en) * | 2010-10-07 | 2017-12-15 | Univ Leuven Kath | Phosphospecific antibodies recognizing tau |
| CA2811188C (en) * | 2011-09-23 | 2020-04-28 | Andrea Pfeifer | Vaccine therapy |
| KR101981351B1 (ko) | 2011-10-07 | 2019-09-02 | 에이씨 이뮨 에스.에이. | 타우를 인식하는 포스포특이적 항체 |
| RU2644242C2 (ru) | 2012-04-05 | 2018-02-08 | Ац Иммуне С.А. | Гуманизированное тау-антитело |
| CN104428411B (zh) * | 2012-05-08 | 2018-11-23 | 健康科学西部大学 | 用于cd4+t细胞群之抗原特异性扩增的标准化离体平台 |
| WO2014150877A2 (en) | 2013-03-15 | 2014-09-25 | Ac Immune S.A. | Anti-tau antibodies and methods of use |
| CN107073297B (zh) | 2014-07-08 | 2021-09-14 | 纽约大学 | Tau显像配体和其在Tau蛋白病的诊断和治疗中的用途 |
| RU2689689C2 (ru) * | 2015-01-23 | 2019-05-28 | Хеликс Байофарма Корпорейшн | Конъюгаты антитело-уреаза для терапевтических целей |
| WO2017027685A2 (en) | 2015-08-13 | 2017-02-16 | New York University | Antibody-based molecules specific for the truncated asp421 epitope of tau and their uses in the diagnosis and treatment of tauopathy |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| CN111787942B (zh) | 2017-10-25 | 2024-03-29 | 杨森制药公司 | 磷酸化Tau肽的组合物及其用途 |
| WO2020160156A2 (en) | 2019-01-30 | 2020-08-06 | Immutics, Inc. | Anti-gal3 antibodies and uses thereof |
| MY206596A (en) | 2019-02-08 | 2024-12-25 | Janssen Pharmaceuticals Inc | Method of safe administration of phosphorylated tau peptide vaccine |
| JOP20210284A1 (ar) * | 2019-04-24 | 2023-01-30 | Janssen Pharmaceuticals Inc | الإعطاء غير المتجانس للقاحات تاو |
| SG11202112329RA (en) * | 2019-05-21 | 2021-12-30 | Ac Immune Sa | Anti-abeta vaccine therapy |
| EP4157338A4 (en) | 2020-05-26 | 2024-11-13 | TrueBinding, Inc. | METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING |
| AU2024211543A1 (en) | 2023-01-26 | 2025-07-17 | Ac Immune Sa | Liposomal construct |
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| WO2007068411A2 (en) * | 2005-12-12 | 2007-06-21 | Ac Immune S.A. | Therapeutic vaccine |
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| US7408027B1 (en) * | 1991-12-06 | 2008-08-05 | Max-Planck-Gesellschaft Zur Forderung Der Wissenchaften | Tools for the diagnosis and treatment of Alzheimer's disease |
| WO1994013795A1 (en) * | 1992-12-14 | 1994-06-23 | N.V. Innogenetics S.A. | Monoclonal antibodies directed against the microtubule-associated protein tau, hybridomas secreting these antibodies, antigen recognition by these monoclonal antibodies and their applications |
| US7427392B1 (en) * | 1994-11-14 | 2008-09-23 | Elan Pharmaceuticals, Inc. | Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-β peptide (x-≧41) and tau |
| US20020086009A1 (en) * | 1996-03-13 | 2002-07-04 | Koichi Ishiguro | Anti-phosphorylated tau protein antibodies and methods for detecting alzheimer`s disease with the use of the same |
| AU5508798A (en) * | 1996-11-19 | 1998-06-10 | Trustees Of The University Of Pennsylvania, The | Diagnostic and therapeutic reagents for alzheimer's disease |
| JP2004503747A (ja) * | 2000-07-11 | 2004-02-05 | モレキュラー ジェリアトリクス コーポレイション | 結合物質の同定するための試薬と方法 |
| AU2003292936A1 (en) | 2002-12-24 | 2004-07-22 | Neurochem (International) Limited | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| US8663650B2 (en) * | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
| EP1494000A1 (en) * | 2003-07-02 | 2005-01-05 | Sicpa Holding S.A. | Method of marking a material with ions already comprised in said material and method of verifying the authenticity of said material |
| US20050261475A1 (en) * | 2004-02-13 | 2005-11-24 | Harvard Medical School | Solid-phase capture-release-tag methods for phosphoproteomic analyses |
| HUE025186T2 (en) * | 2004-02-20 | 2016-02-29 | Ac Immune Sa | Methods and methods using supramolecular constructs |
| US8012936B2 (en) * | 2006-03-29 | 2011-09-06 | New York University | Tau fragments for immunotherapy |
| WO2008140639A2 (en) * | 2007-02-08 | 2008-11-20 | Oligomerix, Inc. | Biomarkers and assays for alzheimer's disease |
| UA107571C2 (xx) * | 2009-04-03 | 2015-01-26 | Фармацевтична композиція |
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2010
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- 2010-03-18 RU RU2011141889/10A patent/RU2579659C2/ru active
- 2010-03-18 JP JP2012500251A patent/JP2012520852A/ja not_active Withdrawn
- 2010-03-18 KR KR1020117024550A patent/KR20120004994A/ko not_active Ceased
- 2010-03-18 CA CA2755683A patent/CA2755683A1/en not_active Abandoned
- 2010-03-18 PT PT107100174T patent/PT2408807T/pt unknown
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- 2010-03-18 SI SI201032083T patent/SI2408807T1/sl unknown
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007068411A2 (en) * | 2005-12-12 | 2007-06-21 | Ac Immune S.A. | Therapeutic vaccine |
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| CERUTTI A., The regulation of IgA class switching, Nat Rev Immunol., June 2008, Vol.8, No.6, pp.421-434. MUHS A., et al., Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice, PNAS, 05.06.2007, Vol.104, No.23, pp.9810-9815. MAIER M., et al., Short amyloid-β (Aβ) immunogens reduce cerebral Aβ load and learning deficits in an Alzheimer’s disease mouse model in the absence of an Aβ-specific cellular immune response, The Journal of neuroscience, May 2006, Vol.26, No.18, pp.4717-4728.EA 10586 B1, 30.10.2008. * |
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| PT2408807T (pt) | 2021-09-03 |
| SG174871A1 (en) | 2011-11-28 |
| IL214919A0 (en) | 2011-11-30 |
| IL214919A (en) | 2016-10-31 |
| RU2011141889A (ru) | 2013-04-27 |
| HUE055739T2 (hu) | 2021-12-28 |
| US20100285108A1 (en) | 2010-11-11 |
| DK2408807T3 (da) | 2021-08-09 |
| MX2011009654A (es) | 2011-10-12 |
| ES2885398T3 (es) | 2021-12-13 |
| WO2010106127A2 (en) | 2010-09-23 |
| AU2010224824A2 (en) | 2011-09-22 |
| CN102428101B (zh) | 2016-03-02 |
| AU2010224824B2 (en) | 2014-02-20 |
| EP3978517A1 (en) | 2022-04-06 |
| JP2012520852A (ja) | 2012-09-10 |
| CN102428101A (zh) | 2012-04-25 |
| WO2010106127A3 (en) | 2011-03-31 |
| EP2408807A2 (en) | 2012-01-25 |
| CA2755683A1 (en) | 2010-09-23 |
| JP2015221809A (ja) | 2015-12-10 |
| AU2010224824A1 (en) | 2011-09-22 |
| KR20120004994A (ko) | 2012-01-13 |
| EP2408807B1 (en) | 2021-07-21 |
| SI2408807T1 (sl) | 2021-11-30 |
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