RU2553633C1 - Ointment for septic and open wounds - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: ointment contains wax 13-15 wt %, glycerol 15-20 % and vegetable oil; the prepared ointment mass is exposed to ozone for 15-20 min in a yield amount of 10 mg/l.

EFFECT: invention provides the advanced healing efficacy with no side effects by reducing the time of wound cleansing from purulo-necrotic tissues.

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Description

The invention relates to medicine, namely to compositions of ingredients that have a therapeutic purpose by external use on the human body.

Closest to the claimed ointment is an ointment for the treatment of frostbite (RF patent No. 2478368, IPC A01K 9/06, A01K 36/21, A01K 9/42, A01P 17/26, 2013), including wax, amaranth oil, glycerin , in the following ratio of components, mass. %: wax 13-15, glycerin 15-20, amaranth oil rest.

This ointment is more universal than those available in the field of its application for various types of wounds, but its main drawback is the slow cleansing of wounds from pus, which delays the healing effect.

The technical result of the invention is aimed at increasing the effectiveness of the healing action in the absence of side effects by reducing the time for cleaning the wound surface from purulent-necrotic tissue.

The technical result is achieved in that the ointment, which includes a bee product, contains wax as a bee product, vegetable oil as a fat product, glycerin, ozone as a means of activating metabolic processes in the following ratio of components, masses. %: wax 13-15; glycerin 15-20; vegetable oil is the rest, while the resulting mass of ointment is ozonized for 15-20 minutes, while the ozone at the outlet is 10 mg / l.

Comparative analysis with the prototype showed that the claimed composition of the ointment differs from the known one in that the resulting mass of ointment is ozonized for 15-20 minutes, while the ozone at the outlet is 10 mg / L.

Ointment is made as follows.

Vegetable oil is brought to a boil in a steam bath, after which wax is added to it until completely dissolved. The resulting mass is stirred and left to boil for 5 minutes, after which it is removed from the heat, cooled to room temperature, glycerin is added, mix thoroughly and the resulting mass of ointment is ozonized for 15-20 minutes, while the ozone at the outlet is 10 mg / L.

The cooled ointment is applied with a sterile medical spatula in a thin layer on a sterile tissue and applied to the wound surface.

The ointment is suitable for more than 2 years from the date of preparation when stored in a cool dark place.

The therapeutic properties of the ointment are as follows.

Vegetable oil contains triglycerides and polyunsaturated fatty acids that promote tissue regeneration.

Wax among other bee products used for ointments has the least reactivity, while in the presence of triglycerides it is able to release oxidized oxygen into the wound, which promotes tissue regeneration.

Glycerin has a softening and at the same time astringent effect, has high hygroscopic, lubricating properties. When applied to the wound surface, it activates metabolic processes in it and has a hemostatic effect.

Ozone for external use in the form of ozonated solutions or oils, etc. It has a direct oxidizing effect on the membrane of microorganisms. Ozone kills almost all types of bacteria, fungi, viruses and protozoa. In this case, gram-positive bacteria and capsular viruses with a lipid bilayer are particularly sensitive to oxidation, in addition, ozone causes a bactericidal effect, which is mediated by the activation of a nonspecific defense system (activation of phagocytosis, enhanced synthesis of interferon cytokines, tumor necrotizing factor, interleukins, as well as components of cellular and humoral immunity). In addition, ozone restores metabolic reactions in tissues at the site of inflammation.

In addition, ozone restores metabolic reactions in tissues at the site of inflammation and corrects the pH by oxidation of double bonds.

The analgesic effect of ozone is due, on the one hand, to the oxidation of the breakdown products of protein molecules, the so-called algopeptides, which act on the nerve endings in damaged tissue and determine the intensity of the pain reaction, on the other hand, the normalization of the antioxidant system and, accordingly, the reduction in the amount of toxic molecular products of lipid peroxidation by cell membranes that alter the function of membrane-built enzymes involved in the synthesis of adenosine triphosphate (ATP), maintaining life inactivity of tissues and organs, promotes epithelization and healing.

The ointment is plastic and, due to the content of the wax-oil-glycerin mixture at its core, has increased penetrating ability in biological tissues.

The ointment is absolutely harmless and does not give side complications.

The therapeutic effect of the ointment was tested in the entire range of changes in the quantitative content of the components.

The ointment was tested on twenty-five patients with various types of burn wounds, pressure sores, trophic ulcers, open and purulent wounds and frostbite.

Example 1

Patient A., 20 years old, Diagnosis: 2-3 degree burn in the face, neck, chest surface of the front surface. 10 days after treatment with ointment, the patient has tender skin, slightly hyperemic.

Example 2

Patient Z., 76 years old, suffers from trophic ulcers of both limbs for 15 years. She was treated repeatedly in a hospital and clinic unsuccessfully. After applying the ointment, the ulcers healed within 1.5 months with a delicate scar tissue.

Example 3

Patient V., 56 years old, was treated with a bite wound (dog bite) a month after unsuccessful treatment in a clinic. After applying the ointment, the wound healed within 2 weeks.

The use of ointment for frostbite gave a positive result. Puffiness was quickly removed, intoxication was not observed, dressings were painless, since the dressings do not stick to the wound surface and are freely removed.

The ointment contains cheap, widespread ingredients, the composition is stable, easy to manufacture. According to its medicinal properties, it can be recommended in hospital therapy in combat conditions.

Claims (1)

An ointment for the treatment of purulent and open wounds, including wax, glycerin, vegetable oil in the following ratio of components, mass. %: wax 13-15; glycerin 15-20; vegetable oil is the rest, characterized in that the resulting mass of ointment is ozonized for 15-20 minutes, while the output ozone is 10 mg / l.