RU2508401C2 - Поксвирусные онколитические векторы - Google Patents
Поксвирусные онколитические векторы Download PDFInfo
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- RU2508401C2 RU2508401C2 RU2010124613/10A RU2010124613A RU2508401C2 RU 2508401 C2 RU2508401 C2 RU 2508401C2 RU 2010124613/10 A RU2010124613/10 A RU 2010124613/10A RU 2010124613 A RU2010124613 A RU 2010124613A RU 2508401 C2 RU2508401 C2 RU 2508401C2
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| Application Number | Priority Date | Filing Date | Title |
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| EP07301556 | 2007-11-19 | ||
| EP07301556.2 | 2007-11-19 | ||
| PCT/EP2008/009721 WO2009065547A2 (en) | 2007-11-19 | 2008-11-17 | Poxviral oncolytic vectors |
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| JP2012515146A (ja) | 2009-01-13 | 2012-07-05 | トランジェーヌ、ソシエテ、アノニム | 免疫刺激のためのサッカロマイセス・セレビシエのミトコンドリア核酸画分の使用 |
| KR20120026526A (ko) | 2009-05-12 | 2012-03-19 | 트랜스진 에스.에이. | 불멸화 조류 세포주 및 그의 용도 |
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| WO2013004658A1 (en) | 2011-07-01 | 2013-01-10 | Transgene Sa | Formulations of 5-fluorocytosine and uses thereof. |
| TWI690322B (zh) | 2012-10-02 | 2020-04-11 | 法商傳斯堅公司 | 含病毒的調配物及其使用 |
| DK3552615T3 (da) | 2014-07-16 | 2022-02-14 | Transgene | Onkolytisk virus til ekspression af immun-checkpoint-modulatorer |
| WO2016009017A1 (en) | 2014-07-16 | 2016-01-21 | Institut Gustave-Roussy | Combination of oncolytic virus with immune checkpoint modulators |
| DK3226894T3 (da) | 2014-12-01 | 2019-10-21 | Transgene Sa | Stabile flydende vacciniavirus-formuleringer |
| EP3256156B1 (en) | 2015-02-13 | 2025-02-12 | Transgene | Immunotherapeutic vaccine and antibody combination therapy |
| WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
| US10639366B2 (en) | 2015-02-25 | 2020-05-05 | Memorial Sloan Kettering Cancer Center | Use of inactivated nonreplicating modified vaccinia virus Ankara (MVA) as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors |
| KR20180006916A (ko) | 2015-04-17 | 2018-01-19 | 메모리얼 슬로안-케터링 캔서 센터 | 고형 종양에 대한 면역치료제로서 mva 또는 mva델타e3l의 용도 |
| AU2017222686B2 (en) | 2016-02-25 | 2021-12-23 | Memorial Sloan Kettering Cancer Center | Replication competent attenuated vaccinia viruses with deletion of thymidine kinase with and without the expression of human Flt3L or GM-CSF for cancer immunotherapy |
| KR20180130500A (ko) | 2016-02-25 | 2018-12-07 | 메모리얼 슬로안 케터링 캔서 센터 | 인간 flt3l을 발현하는 재조합 mva 또는 mvaδe3l 및 고형 종양에 대한 면역요법제로서 그의 용도 |
| CA3023022A1 (en) | 2016-05-04 | 2017-11-09 | Transgene Sa | Combination therapy with cpg tlr9 ligand |
| KR102557818B1 (ko) * | 2016-08-09 | 2023-07-20 | 시티 오브 호프 | 키메라 폭스바이러스 조성물 및 이의 용도 |
| EP3522920A2 (en) | 2016-10-10 | 2019-08-14 | Transgene SA | Immunotherapeutic product and mdsc modulator combination therapy |
| US20190330655A1 (en) | 2016-12-28 | 2019-10-31 | Transgene Sa | Oncolytic viruses and therapeutic molecules |
| EP3621646A4 (en) | 2017-05-12 | 2021-06-02 | Memorial Sloan Kettering Cancer Center | VACCINIA VIRUS MUTANTS FOR CANCER IMMUNOTHERAPY |
| KR102684237B1 (ko) | 2017-06-21 | 2024-07-11 | 트랜스진 | 개인 맞춤형 백신 |
| WO2019020543A1 (en) | 2017-07-28 | 2019-01-31 | Transgene Sa | ONCOLYTIC VIRUSES EXPRESSING AGENTS TARGETING METABOLIC IMMUNE MODULATORS |
| US12364724B2 (en) | 2017-08-11 | 2025-07-22 | City Of Hope | Oncolytic virus expressing a car T cell target and uses thereof |
| WO2019148109A1 (en) * | 2018-01-26 | 2019-08-01 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Expression of metabolic modulators in tumor microenvironment to improve tumor therapy |
| CN116162654A (zh) | 2018-09-15 | 2023-05-26 | 纪念斯隆凯特琳癌症中心 | 用于癌症免疫疗法的重组痘病毒 |
| SG11202106898VA (en) | 2018-12-28 | 2021-07-29 | Transgene Sa | M2-defective poxvirus |
| WO2022148736A1 (en) | 2021-01-05 | 2022-07-14 | Transgene | Vectorization of muc1 t cell engager |
| WO2023213764A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf |
| WO2023213763A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab |
| US20260015405A1 (en) | 2022-07-01 | 2026-01-15 | Transgene | Fusion protein comprising a surfactant-protein-d and a member of the tnfsf |
| WO2026041811A1 (en) | 2024-08-23 | 2026-02-26 | Transgene | Recombinant poxvirus and method for regulating the expression of toxic conditional gene products of said recombinant poxvirus in a producing cell |
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| EP1367128A1 (en) * | 1991-03-07 | 2003-12-03 | Connaught Technology Corporation | Genetically engineered vaccine strain |
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| US6897057B1 (en) * | 1999-08-31 | 2005-05-24 | The General Hospital Corporation | Cell-specific and/or tumor-specific promoter retargeting of herpes γ 34.5 gene expression |
| US8778328B2 (en) * | 2007-11-19 | 2014-07-15 | Transgene S.A. | Poxviral oncolytic vectors |
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- 2008-11-17 EP EP08851361.9A patent/EP2212423B1/en not_active Not-in-force
- 2008-11-17 PL PL08851361T patent/PL2212423T3/pl unknown
- 2008-11-17 BR BRPI0820578-7A patent/BRPI0820578A2/pt not_active Application Discontinuation
- 2008-11-17 RU RU2010124613/10A patent/RU2508401C2/ru not_active IP Right Cessation
- 2008-11-17 JP JP2010533511A patent/JP5710262B2/ja not_active Expired - Fee Related
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- 2008-11-17 HR HRP20150360TT patent/HRP20150360T1/hr unknown
- 2008-11-17 ES ES08851361.9T patent/ES2535633T3/es active Active
- 2008-11-17 RU RU2013129678/10A patent/RU2557312C2/ru not_active IP Right Cessation
- 2008-11-17 NZ NZ584201A patent/NZ584201A/en not_active IP Right Cessation
- 2008-11-17 US US12/743,412 patent/US9180150B2/en not_active Expired - Fee Related
- 2008-11-17 MX MX2010005273A patent/MX2010005273A/es active IP Right Grant
- 2008-11-17 WO PCT/EP2008/009721 patent/WO2009065547A2/en not_active Ceased
- 2008-11-17 CN CN2008801168337A patent/CN101868546B/zh not_active Expired - Fee Related
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2010
- 2010-03-16 IL IL204539A patent/IL204539A/en active IP Right Grant
- 2010-06-17 ZA ZA2010/04286A patent/ZA201004286B/en unknown
- 2010-06-18 CR CR11520A patent/CR11520A/es not_active Application Discontinuation
- 2010-06-18 CO CO10073787A patent/CO6210761A2/es not_active Application Discontinuation
- 2010-06-18 EC EC2010010287A patent/ECSP10010287A/es unknown
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