CA2705873C - Poxviral oncolytic vectors - Google Patents
Poxviral oncolytic vectors Download PDFInfo
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- CA2705873C CA2705873C CA2705873A CA2705873A CA2705873C CA 2705873 C CA2705873 C CA 2705873C CA 2705873 A CA2705873 A CA 2705873A CA 2705873 A CA2705873 A CA 2705873A CA 2705873 C CA2705873 C CA 2705873C
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- poxvirus
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07301556.2 | 2007-11-19 | ||
| EP07301556 | 2007-11-19 | ||
| PCT/EP2008/009721 WO2009065547A2 (en) | 2007-11-19 | 2008-11-17 | Poxviral oncolytic vectors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2705873A1 CA2705873A1 (en) | 2009-05-28 |
| CA2705873C true CA2705873C (en) | 2012-06-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2705873A Expired - Fee Related CA2705873C (en) | 2007-11-19 | 2008-11-17 | Poxviral oncolytic vectors |
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| EP (1) | EP2212423B1 (enExample) |
| JP (1) | JP5710262B2 (enExample) |
| KR (1) | KR101542275B1 (enExample) |
| CN (1) | CN101868546B (enExample) |
| AU (1) | AU2008328258B2 (enExample) |
| BR (1) | BRPI0820578A2 (enExample) |
| CA (1) | CA2705873C (enExample) |
| CO (1) | CO6210761A2 (enExample) |
| CR (1) | CR11520A (enExample) |
| DK (1) | DK2212423T3 (enExample) |
| EC (1) | ECSP10010287A (enExample) |
| ES (1) | ES2535633T3 (enExample) |
| HR (1) | HRP20150360T1 (enExample) |
| IL (1) | IL204539A (enExample) |
| MX (1) | MX2010005273A (enExample) |
| NZ (1) | NZ584201A (enExample) |
| PL (1) | PL2212423T3 (enExample) |
| RU (2) | RU2557312C2 (enExample) |
| WO (1) | WO2009065547A2 (enExample) |
| ZA (1) | ZA201004286B (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2744294A1 (en) | 2009-01-13 | 2010-07-22 | Transgene Sa | Use of a saccharomyces cerevisiae mitochondrial nucleic acids fraction for immune stimulation |
| SG176554A1 (en) | 2009-05-12 | 2012-01-30 | Transgene Sa | Method for orthopoxvirus production and purification |
| EP2452194B1 (en) | 2009-07-10 | 2015-11-11 | Transgene SA | Biomarker for selecting patients and related methods |
| WO2013004658A1 (en) | 2011-07-01 | 2013-01-10 | Transgene Sa | Formulations of 5-fluorocytosine and uses thereof. |
| TWI690322B (zh) | 2012-10-02 | 2020-04-11 | 法商傳斯堅公司 | 含病毒的調配物及其使用 |
| ES2833425T3 (es) * | 2014-07-16 | 2021-06-15 | Roussy Inst Gustave | Combinación de virus oncolítico con moduladores de punto de control inmunitario |
| DK3552615T3 (da) | 2014-07-16 | 2022-02-14 | Transgene | Onkolytisk virus til ekspression af immun-checkpoint-modulatorer |
| US10517943B2 (en) | 2014-12-01 | 2019-12-31 | Transgene S.A. | Stable liquid vaccinia virus formulations |
| CA2975432A1 (en) | 2015-02-13 | 2016-08-18 | Transgene Sa | Immunotherapeutic vaccine and antibody combination therapy |
| WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
| EP4122492A1 (en) | 2015-02-25 | 2023-01-25 | Memorial Sloan Kettering Cancer Center | Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors |
| KR20180006916A (ko) | 2015-04-17 | 2018-01-19 | 메모리얼 슬로안-케터링 캔서 센터 | 고형 종양에 대한 면역치료제로서 mva 또는 mva델타e3l의 용도 |
| WO2017147554A2 (en) | 2016-02-25 | 2017-08-31 | Memorial Sloan-Kettering Cancer Center | Recombinant mva or mvadele3l expressing human flt3l and use thereof as immuno-therapeutic agents against solid tumors |
| CN109152815B (zh) | 2016-02-25 | 2022-10-18 | 纪念斯隆凯特琳癌症中心 | 用于癌症免疫治疗的具有胸苷激酶缺失和具有或不具有人flt3l或gm-csf表达的复制型减毒痘苗病毒 |
| CA3023022A1 (en) | 2016-05-04 | 2017-11-09 | Transgene Sa | Combination therapy with cpg tlr9 ligand |
| KR20250067190A (ko) * | 2016-08-09 | 2025-05-14 | 시티 오브 호프 | 키메라 폭스바이러스 조성물 및 이의 용도 |
| WO2018069316A2 (en) | 2016-10-10 | 2018-04-19 | Transgene Sa | Immunotherapeutic product and mdsc modulator combination therapy |
| CA3045228C (en) | 2016-12-28 | 2024-01-02 | Transgene Sa | Oncolytic viruses and therapeutic molecules |
| CN111107872A (zh) | 2017-05-12 | 2020-05-05 | 纪念斯隆-凯特林癌症中心 | 有用于癌症免疫疗法的牛痘病毒突变体 |
| KR20240113607A (ko) | 2017-06-21 | 2024-07-22 | 트랜스진 | 개인 맞춤형 백신 |
| WO2019020543A1 (en) | 2017-07-28 | 2019-01-31 | Transgene Sa | ONCOLYTIC VIRUSES EXPRESSING AGENTS TARGETING METABOLIC IMMUNE MODULATORS |
| CN111163803B (zh) * | 2017-08-11 | 2025-05-09 | 希望之城公司 | 表达car t细胞靶物的溶瘤病毒及其用途 |
| JP2021511060A (ja) * | 2018-01-26 | 2021-05-06 | ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | 腫瘍治療を改善するための、腫瘍微小環境における代謝モジュレーターの発現 |
| CA3112654A1 (en) | 2018-09-15 | 2020-03-19 | Memorial Sloan Kettering Cancer Center | Recombinant poxviruses for cancer immunotherapy |
| CA3124773A1 (en) | 2018-12-28 | 2020-07-02 | Transgene | M2-defective poxvirus |
| WO2022148736A1 (en) | 2021-01-05 | 2022-07-14 | Transgene | Vectorization of muc1 t cell engager |
| WO2023213764A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf |
| WO2023213763A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab |
| CN119654339A (zh) | 2022-07-01 | 2025-03-18 | 特兰斯吉恩股份有限公司 | 包含表面活性蛋白-d和tnfsf成员的融合蛋白 |
| US12698512B2 (en) | 2023-11-06 | 2026-08-04 | City Of Hope | Methods comprising oncolytic viruses expressing CD19T and bispecific T cell engagers |
| WO2026041811A1 (en) | 2024-08-23 | 2026-02-26 | Transgene | Recombinant poxvirus and method for regulating the expression of toxic conditional gene products of said recombinant poxvirus in a producing cell |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364773A (en) * | 1991-03-07 | 1994-11-15 | Virogenetics Corporation | Genetically engineered vaccine strain |
| US5225336A (en) * | 1989-03-08 | 1993-07-06 | Health Research Incorporated | Recombinant poxvirus host range selection system |
| EP0575491B1 (en) * | 1991-03-07 | 2003-08-13 | Virogenetics Corporation | Genetically engineered vaccine strain |
| EP1367128A1 (en) * | 1991-03-07 | 2003-12-03 | Connaught Technology Corporation | Genetically engineered vaccine strain |
| US20030044384A1 (en) * | 1997-10-09 | 2003-03-06 | Pro-Virus, Inc. | Treatment of neoplasms with viruses |
| AU5446700A (en) * | 1999-05-28 | 2000-12-18 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | A combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector |
| US6897057B1 (en) * | 1999-08-31 | 2005-05-24 | The General Hospital Corporation | Cell-specific and/or tumor-specific promoter retargeting of herpes γ 34.5 gene expression |
| MXPA05013879A (es) * | 2003-06-18 | 2006-06-27 | Genelux Corp | Virus de la vaccinia recombinantes modificados y otros microorganismos, y usos de los mismos. |
| DK2212345T3 (en) * | 2007-11-19 | 2016-03-21 | Transgene Sa | Oncolytic poxvirus vectors |
-
2008
- 2008-11-17 EP EP08851361.9A patent/EP2212423B1/en not_active Not-in-force
- 2008-11-17 RU RU2013129678/10A patent/RU2557312C2/ru not_active IP Right Cessation
- 2008-11-17 DK DK08851361T patent/DK2212423T3/en active
- 2008-11-17 AU AU2008328258A patent/AU2008328258B2/en not_active Ceased
- 2008-11-17 PL PL08851361T patent/PL2212423T3/pl unknown
- 2008-11-17 NZ NZ584201A patent/NZ584201A/en not_active IP Right Cessation
- 2008-11-17 ES ES08851361.9T patent/ES2535633T3/es active Active
- 2008-11-17 KR KR1020107010821A patent/KR101542275B1/ko not_active Expired - Fee Related
- 2008-11-17 WO PCT/EP2008/009721 patent/WO2009065547A2/en not_active Ceased
- 2008-11-17 MX MX2010005273A patent/MX2010005273A/es active IP Right Grant
- 2008-11-17 BR BRPI0820578-7A patent/BRPI0820578A2/pt not_active Application Discontinuation
- 2008-11-17 CA CA2705873A patent/CA2705873C/en not_active Expired - Fee Related
- 2008-11-17 HR HRP20150360TT patent/HRP20150360T1/hr unknown
- 2008-11-17 US US12/743,412 patent/US9180150B2/en not_active Expired - Fee Related
- 2008-11-17 RU RU2010124613/10A patent/RU2508401C2/ru not_active IP Right Cessation
- 2008-11-17 JP JP2010533511A patent/JP5710262B2/ja not_active Expired - Fee Related
- 2008-11-17 CN CN2008801168337A patent/CN101868546B/zh not_active Expired - Fee Related
-
2010
- 2010-03-16 IL IL204539A patent/IL204539A/en active IP Right Grant
- 2010-06-17 ZA ZA2010/04286A patent/ZA201004286B/en unknown
- 2010-06-18 EC EC2010010287A patent/ECSP10010287A/es unknown
- 2010-06-18 CO CO10073787A patent/CO6210761A2/es not_active Application Discontinuation
- 2010-06-18 CR CR11520A patent/CR11520A/es not_active Application Discontinuation
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Legal Events
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| EEER | Examination request | ||
| MKLA | Lapsed |
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| MKLA | Lapsed |
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