RU2492877C2 - Ингалятор, содержащий основание, имеющее большое количество содержащих лекарственное средство герметичных полостей - Google Patents
Ингалятор, содержащий основание, имеющее большое количество содержащих лекарственное средство герметичных полостей Download PDFInfo
- Publication number
- RU2492877C2 RU2492877C2 RU2010133721/14A RU2010133721A RU2492877C2 RU 2492877 C2 RU2492877 C2 RU 2492877C2 RU 2010133721/14 A RU2010133721/14 A RU 2010133721/14A RU 2010133721 A RU2010133721 A RU 2010133721A RU 2492877 C2 RU2492877 C2 RU 2492877C2
- Authority
- RU
- Russia
- Prior art keywords
- cavity
- foil
- base
- inhaler
- attached
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims abstract description 49
- 229940079593 drug Drugs 0.000 title claims abstract description 44
- 239000011888 foil Substances 0.000 claims abstract description 175
- 125000006850 spacer group Chemical group 0.000 claims abstract description 56
- 239000012530 fluid Substances 0.000 claims abstract description 33
- 238000000034 method Methods 0.000 claims abstract description 16
- 238000007789 sealing Methods 0.000 claims abstract description 9
- 238000000926 separation method Methods 0.000 claims description 103
- 239000011247 coating layer Substances 0.000 claims description 10
- 238000009826 distribution Methods 0.000 claims description 10
- 229940126601 medicinal product Drugs 0.000 claims description 8
- 239000010410 layer Substances 0.000 claims description 7
- 238000006073 displacement reaction Methods 0.000 claims 1
- 239000000843 powder Substances 0.000 abstract description 8
- 239000000126 substance Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 2
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- 239000003795 chemical substances by application Substances 0.000 description 9
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 description 6
- 229960004436 budesonide Drugs 0.000 description 6
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- YEEZWCHGZNKEEK-UHFFFAOYSA-N Zafirlukast Chemical compound COC1=CC(C(=O)NS(=O)(=O)C=2C(=CC=CC=2)C)=CC=C1CC(C1=C2)=CN(C)C1=CC=C2NC(=O)OC1CCCC1 YEEZWCHGZNKEEK-UHFFFAOYSA-N 0.000 description 3
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- QLIIKPVHVRXHRI-CXSFZGCWSA-N mometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O QLIIKPVHVRXHRI-CXSFZGCWSA-N 0.000 description 3
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- XWTYSIMOBUGWOL-UHFFFAOYSA-N (+-)-Terbutaline Chemical compound CC(C)(C)NCC(O)C1=CC(O)=CC(O)=C1 XWTYSIMOBUGWOL-UHFFFAOYSA-N 0.000 description 1
- RATSWNOMCHFQGJ-TUYNVFRMSA-N (e)-but-2-enedioic acid;n-[2-hydroxy-5-[(1s)-1-hydroxy-2-[[(2s)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide;dihydrate Chemical compound O.O.OC(=O)\C=C\C(O)=O.C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1.C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1 RATSWNOMCHFQGJ-TUYNVFRMSA-N 0.000 description 1
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
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- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
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- 229960001022 fenoterol Drugs 0.000 description 1
- LSLYOANBFKQKPT-UHFFFAOYSA-N fenoterol Chemical compound C=1C(O)=CC(O)=CC=1C(O)CNC(C)CC1=CC=C(O)C=C1 LSLYOANBFKQKPT-UHFFFAOYSA-N 0.000 description 1
- 229960000289 fluticasone propionate Drugs 0.000 description 1
- WMWTYOKRWGGJOA-CENSZEJFSA-N fluticasone propionate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(OC(=O)CC)[C@@]2(C)C[C@@H]1O WMWTYOKRWGGJOA-CENSZEJFSA-N 0.000 description 1
- 229940050287 formoterol / mometasone Drugs 0.000 description 1
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- KEWHKYJURDBRMN-ZEODDXGYSA-M ipratropium bromide hydrate Chemical compound O.[Br-].O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 KEWHKYJURDBRMN-ZEODDXGYSA-M 0.000 description 1
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- 229960002720 reproterol Drugs 0.000 description 1
- WVLAAKXASPCBGT-UHFFFAOYSA-N reproterol Chemical compound C1=2C(=O)N(C)C(=O)N(C)C=2N=CN1CCCNCC(O)C1=CC(O)=CC(O)=C1 WVLAAKXASPCBGT-UHFFFAOYSA-N 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 229950004432 rofleponide Drugs 0.000 description 1
- IXTCZMJQGGONPY-XJAYAHQCSA-N rofleponide Chemical compound C1([C@@H](F)C2)=CC(=O)CC[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3O[C@@H](CCC)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O IXTCZMJQGGONPY-XJAYAHQCSA-N 0.000 description 1
- -1 rrofleponide Chemical compound 0.000 description 1
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- 150000003431 steroids Chemical class 0.000 description 1
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- PJFHZKIDENOSJB-JIVDDGRNSA-N symbicort inhalation aerosol Chemical compound C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1.C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O PJFHZKIDENOSJB-JIVDDGRNSA-N 0.000 description 1
- 229960000195 terbutaline Drugs 0.000 description 1
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- KFVSLSTULZVNPG-UHFFFAOYSA-N terbutaline sulfate Chemical compound [O-]S([O-])(=O)=O.CC(C)(C)[NH2+]CC(O)C1=CC(O)=CC(O)=C1.CC(C)(C)[NH2+]CC(O)C1=CC(O)=CC(O)=C1 KFVSLSTULZVNPG-UHFFFAOYSA-N 0.000 description 1
- IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0043—Non-destructive separation of the package, e.g. peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/062—Desiccants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Basic Packing Technique (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2786508P | 2008-02-12 | 2008-02-12 | |
| US61/027.865 | 2008-02-12 | ||
| US61/027,865 | 2008-02-12 | ||
| US9025508P | 2008-08-20 | 2008-08-20 | |
| US61/090,255 | 2008-08-20 | ||
| PCT/SE2009/050148 WO2009102276A1 (en) | 2008-02-12 | 2009-02-11 | Inhaler comprising a base having a plurality of medicament containing sealed cavities |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2010133721A RU2010133721A (ru) | 2012-03-20 |
| RU2492877C2 true RU2492877C2 (ru) | 2013-09-20 |
Family
ID=40957181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2010133721/14A RU2492877C2 (ru) | 2008-02-12 | 2009-02-11 | Ингалятор, содержащий основание, имеющее большое количество содержащих лекарственное средство герметичных полостей |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8393322B2 (enExample) |
| EP (1) | EP2252354A4 (enExample) |
| JP (1) | JP5491418B2 (enExample) |
| KR (1) | KR20100118112A (enExample) |
| CN (1) | CN101945682B (enExample) |
| AU (1) | AU2009213182B2 (enExample) |
| BR (1) | BRPI0907713A2 (enExample) |
| CA (1) | CA2714660A1 (enExample) |
| MX (1) | MX2010007881A (enExample) |
| NZ (1) | NZ586698A (enExample) |
| RU (1) | RU2492877C2 (enExample) |
| WO (1) | WO2009102276A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20090136A1 (es) * | 2007-06-01 | 2009-03-11 | Boehringer Ingelheim Int | Dispositivo dispensador |
| MX2010007881A (es) * | 2008-02-12 | 2010-08-06 | Astrazeneca Ab | Inhalador que comprende una base que tiene una pluralidad de cavidades selladas que contienen medicamento. |
| WO2010042033A1 (en) * | 2008-10-08 | 2010-04-15 | Astrazeneca Ab | Inhalation device and method of dispensing medicament |
| MX2012008508A (es) * | 2010-01-20 | 2012-08-17 | Pfizer Ltd | Dispositivo para suministrar una pluralidad de dosis unitarias de polvo seco, e inhalador que comprende tal dispositivo. |
| CN104519934B (zh) * | 2012-07-31 | 2017-07-07 | 赛诺菲股份有限公司 | 用于药物输送装置的组合体 |
| WO2017011867A1 (en) * | 2015-07-20 | 2017-01-26 | Medical Developments International Limited | Inhaler device for inhalable liquids |
| US20240139440A1 (en) * | 2021-01-28 | 2024-05-02 | Iconovo Ab | Medicament packaging |
| US20250082872A1 (en) * | 2021-01-28 | 2025-03-13 | Iconovo Ab | Dry powder inhaler |
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| WO2007118343A1 (de) * | 2006-04-13 | 2007-10-25 | Boehringer Ingelheim International Gmbh | Medikamenten-ausgabevorrichtung, medikamentenmagazin dafür und verfahren zur entnahme eines medikaments aus einer medikamentenkammer |
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| GB9920839D0 (en) * | 1999-09-04 | 1999-11-10 | Innovata Biomed Ltd | Inhaler |
| US7069929B2 (en) * | 2000-02-01 | 2006-07-04 | Quadrant Technologies Limited | Dry powder inhaler |
| AU2001250901A1 (en) | 2000-03-27 | 2001-10-08 | Dura Pharmaceuticals, Inc. | Containers for individual doses of an inhalable pharmaceutical |
| US6948494B1 (en) * | 2000-05-10 | 2005-09-27 | Innovative Devices, Llc. | Medicament container with same side airflow inlet and outlet and method of use |
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| WO2003103563A2 (en) | 2002-06-07 | 2003-12-18 | Sun Pharmaceutical Industries Limited | Powder inhaler |
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| GB2401548B (en) * | 2003-05-13 | 2005-07-13 | Boots Healthcare Int Ltd | Improvements relating to vaporisers |
| PL1718353T3 (pl) * | 2004-02-24 | 2020-06-01 | Microdose Therapeutx, Inc. | Urządzenie do dostarczania leku na bazie strugi syntetycznej |
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| DE102006023662A1 (de) * | 2006-05-18 | 2007-11-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator |
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| AU2009213181B2 (en) * | 2008-02-12 | 2012-02-23 | Astrazeneca Ab | Inhaler comprising a base having at least one sealed cavity containing medicament |
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2009
- 2009-02-11 MX MX2010007881A patent/MX2010007881A/es active IP Right Grant
- 2009-02-11 NZ NZ586698A patent/NZ586698A/en unknown
- 2009-02-11 JP JP2010546728A patent/JP5491418B2/ja not_active Expired - Fee Related
- 2009-02-11 AU AU2009213182A patent/AU2009213182B2/en not_active Ceased
- 2009-02-11 CA CA2714660A patent/CA2714660A1/en not_active Abandoned
- 2009-02-11 KR KR1020107017834A patent/KR20100118112A/ko not_active Abandoned
- 2009-02-11 BR BRPI0907713-8A patent/BRPI0907713A2/pt not_active IP Right Cessation
- 2009-02-11 WO PCT/SE2009/050148 patent/WO2009102276A1/en not_active Ceased
- 2009-02-11 CN CN2009801049050A patent/CN101945682B/zh not_active Expired - Fee Related
- 2009-02-11 EP EP09709949.3A patent/EP2252354A4/en not_active Withdrawn
- 2009-02-11 US US12/867,423 patent/US8393322B2/en not_active Expired - Fee Related
- 2009-02-11 RU RU2010133721/14A patent/RU2492877C2/ru not_active IP Right Cessation
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2013
- 2013-02-07 US US13/761,782 patent/US9174011B2/en not_active Expired - Fee Related
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| RU2181603C2 (ru) * | 1996-04-25 | 2002-04-27 | Астразенека Аб | Ингалятор |
| WO2000053248A1 (en) * | 1999-03-10 | 2000-09-14 | Glaxo Group Limited | Improvements relating to an inhalation device |
| WO2005030305A1 (en) * | 2003-09-26 | 2005-04-07 | Innovata Biomed Limited | Assembly for opening medicament containers, particularly containers for a powdered medicament |
| WO2007118343A1 (de) * | 2006-04-13 | 2007-10-25 | Boehringer Ingelheim International Gmbh | Medikamenten-ausgabevorrichtung, medikamentenmagazin dafür und verfahren zur entnahme eines medikaments aus einer medikamentenkammer |
Also Published As
| Publication number | Publication date |
|---|---|
| US20130220320A1 (en) | 2013-08-29 |
| US8393322B2 (en) | 2013-03-12 |
| KR20100118112A (ko) | 2010-11-04 |
| AU2009213182B2 (en) | 2012-06-07 |
| RU2010133721A (ru) | 2012-03-20 |
| BRPI0907713A2 (pt) | 2015-07-21 |
| JP2011511691A (ja) | 2011-04-14 |
| US20100326440A1 (en) | 2010-12-30 |
| CA2714660A1 (en) | 2009-08-20 |
| EP2252354A1 (en) | 2010-11-24 |
| US9174011B2 (en) | 2015-11-03 |
| AU2009213182A1 (en) | 2009-08-20 |
| CN101945682A (zh) | 2011-01-12 |
| MX2010007881A (es) | 2010-08-06 |
| WO2009102276A1 (en) | 2009-08-20 |
| EP2252354A4 (en) | 2013-10-02 |
| NZ586698A (en) | 2012-07-27 |
| JP5491418B2 (ja) | 2014-05-14 |
| CN101945682B (zh) | 2013-12-04 |
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| Date | Code | Title | Description |
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| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20160212 |