RU2426738C2 - Очистка белков с помощью катионного поверхностно-активного вещества - Google Patents

Очистка белков с помощью катионного поверхностно-активного вещества Download PDF

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Publication number
RU2426738C2
RU2426738C2 RU2007141623/10A RU2007141623A RU2426738C2 RU 2426738 C2 RU2426738 C2 RU 2426738C2 RU 2007141623/10 A RU2007141623/10 A RU 2007141623/10A RU 2007141623 A RU2007141623 A RU 2007141623A RU 2426738 C2 RU2426738 C2 RU 2426738C2
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RU
Russia
Prior art keywords
protein
target protein
proteins
solution
uricase
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RU2007141623/10A
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English (en)
Russian (ru)
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RU2007141623A (ru
Inventor
Меир ФИШЕР (IL)
Меир ФИШЕР
Элияху ХАРОШ (IL)
Элияху ХАРОШ
Original Assignee
Савиент Фармасьютикалз, Инк.
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Publication of RU2007141623A publication Critical patent/RU2007141623A/ru
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/30Extraction; Separation; Purification by precipitation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/565IFN-beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0044Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
    • C12N9/0046Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7) with oxygen as acceptor (1.7.3)
    • C12N9/0048Uricase (1.7.3.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y107/00Oxidoreductases acting on other nitrogenous compounds as donors (1.7)
    • C12Y107/03Oxidoreductases acting on other nitrogenous compounds as donors (1.7) with oxygen as acceptor (1.7.3)
    • C12Y107/03003Factor-independent urate hydroxylase (1.7.3.3), i.e. uricase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
RU2007141623/10A 2005-04-11 2006-04-12 Очистка белков с помощью катионного поверхностно-активного вещества RU2426738C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67052005P 2005-04-11 2005-04-11
US60/670,520 2005-04-11

Publications (2)

Publication Number Publication Date
RU2007141623A RU2007141623A (ru) 2009-08-10
RU2426738C2 true RU2426738C2 (ru) 2011-08-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2007141623/10A RU2426738C2 (ru) 2005-04-11 2006-04-12 Очистка белков с помощью катионного поверхностно-активного вещества

Country Status (9)

Country Link
US (2) US20220073886A1 (cs)
AU (1) AU2006339865B2 (cs)
BR (1) BRPI0612943A2 (cs)
CA (1) CA2611249C (cs)
CZ (1) CZ305852B6 (cs)
NZ (1) NZ562293A (cs)
RU (1) RU2426738C2 (cs)
TW (1) TWI418564B (cs)
ZA (1) ZA200708652B (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107475221A (zh) * 2017-09-19 2017-12-15 青岛农业大学 一种新型溶菌酶制剂及其制备方法
CN109430514B (zh) * 2018-11-02 2022-07-26 广东海洋大学 一种制备罗非鱼-豆粕共沉淀蛋白的方法
WO2020160322A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Tolerization reduces intolerance to pegloticase and prolongs the urate lowering effect (triple)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485176A (en) * 1982-06-28 1984-11-27 E. I. Du Pont De Nemours & Company Turbidimetric method for measuring protein in urine and cerebrospinal fluid
RU2105812C1 (ru) * 1989-07-13 1998-02-27 Санофи Полипептид, обладающий уратоксидазной активностью, фрагмент днк, обеспечивающий экспрессию полипептида с уратоксидазной активностью (варианты), вектор экспрессии, содержащий фрагмент днк, обеспечивающий экспрессию полипептида с уратоксидазной активностью (варианты), штамм, экспрессирующий полипептид, обладающий уратоксидазной активностью (варианты), способ получения полипептида, обладающего уратоксидазной активностью

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3451996A (en) * 1968-02-12 1969-06-24 Thompson Farms Co Method for the preparation of heparin
AU597924B2 (en) * 1985-12-11 1990-06-14 Natinco Nv Solubilization of protein aggregates
JPH01216939A (ja) * 1988-02-24 1989-08-30 Hoechst Japan Kk 末熟児頭蓋内出血阻止剤
US6783965B1 (en) * 2000-02-10 2004-08-31 Mountain View Pharmaceuticals, Inc. Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
WO2004092393A1 (en) * 2003-01-09 2004-10-28 Genentech, Inc. Purification of polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485176A (en) * 1982-06-28 1984-11-27 E. I. Du Pont De Nemours & Company Turbidimetric method for measuring protein in urine and cerebrospinal fluid
RU2105812C1 (ru) * 1989-07-13 1998-02-27 Санофи Полипептид, обладающий уратоксидазной активностью, фрагмент днк, обеспечивающий экспрессию полипептида с уратоксидазной активностью (варианты), вектор экспрессии, содержащий фрагмент днк, обеспечивающий экспрессию полипептида с уратоксидазной активностью (варианты), штамм, экспрессирующий полипептид, обладающий уратоксидазной активностью (варианты), способ получения полипептида, обладающего уратоксидазной активностью

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZHANG W. ET AL. Forward and backward extraction of BSA using mixed reverse micellar system of СТАВ and alkyl halides. // J. Biochemical Engineering, 2002, v.2, n.1, pp.1-5. ZHANG T. ET AL. Affinity extraction of BSA with reversed micellar system composed of unbound Cibacron Blue. // Biotechnol. Prog., 1999, v.15, n.6, pp.1078-82. *

Also Published As

Publication number Publication date
AU2006339865B2 (en) 2012-01-12
CA2611249C (en) 2014-10-14
US20240026312A1 (en) 2024-01-25
RU2007141623A (ru) 2009-08-10
TW200722435A (en) 2007-06-16
CA2611249A1 (en) 2006-10-11
CZ305852B6 (cs) 2016-04-13
AU2006339865A1 (en) 2007-11-08
TWI418564B (zh) 2013-12-11
US20220073886A1 (en) 2022-03-10
AU2006339865A8 (en) 2008-08-07
NZ562293A (en) 2011-06-30
ZA200708652B (en) 2010-03-31
BRPI0612943A2 (pt) 2012-10-09
CZ2007701A3 (cs) 2008-04-16

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Effective date: 20141209

MM4A The patent is invalid due to non-payment of fees

Effective date: 20190413