RU2413529C2 - Применение цитокина из семейства интерлейкина-6 для получения композиции для комбинированного введения с интерфероном-альфа - Google Patents
Применение цитокина из семейства интерлейкина-6 для получения композиции для комбинированного введения с интерфероном-альфа Download PDFInfo
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- A61P31/12—Antivirals
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P31/20—Antivirals for DNA viruses
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5415—Leukaemia inhibitory factor [LIF]
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- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5431—IL-11
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- C07—ORGANIC CHEMISTRY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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| ES200501468A ES2302402B1 (es) | 2005-06-16 | 2005-06-16 | Uso de una citoquina de la familia de interleuquina-6 en la preparacion de una composicion para administracion combinada con interferon-alfa. |
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| UA106591C2 (uk) * | 2008-07-23 | 2014-09-25 | Тамара Алєксандровна Віткалова | Спосіб лікування гепатиту с з використанням інтерферону та інтерлейкіну-1 |
| JP2010059081A (ja) * | 2008-09-02 | 2010-03-18 | Okayama Univ | オンコスタチンｍを含有する抗ｈｃｖ剤およびその利用 |
| ES2342529B1 (es) * | 2008-10-07 | 2011-05-11 | Proyecto De Biomedicina Cima, S.L. | Oncostatina m como potenciador de la actividad inmunoestimuladora de celulas epiteliales humanas. |
| WO2011098644A2 (es) | 2010-02-09 | 2011-08-18 | Proyecto De Biomedicina Cima, S.L. | Composiciones para el tratamiento de enfermedades infecciosas y tumorales |
| CN109562113A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的螺环降解决定子体 |
| CN109562107A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的杂环降解决定子体 |
| CN121974842A (zh) | 2016-05-10 | 2026-05-05 | C4医药公司 | 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体 |
| WO2017197046A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | C3-carbon linked glutarimide degronimers for target protein degradation |
| CN110636854A (zh) | 2017-03-31 | 2019-12-31 | 阿卡尼斯生物技术F&E有限责任两合公司 | 非黑素瘤皮肤癌(nmsc)的预防和治疗 |
| EP4717317A3 (en) | 2017-06-20 | 2026-06-03 | C4 Therapeutics, Inc. | N/o-linked degrons and degronimers for protein degradation |
| CN113197910B (zh) * | 2021-05-14 | 2022-09-23 | 苏州大学 | 一种基于阿司匹林及其代谢产物提高干扰素抗病毒活性的抗病毒药盒 |
Citations (3)
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|---|---|---|---|---|
| EP0858343A1 (en) * | 1995-11-02 | 1998-08-19 | Schering Corporation | Continuous low-dose cytokine infusion therapy |
| RU2128056C1 (ru) * | 1992-04-15 | 1999-03-27 | Амген Инк. | Способы и препараты для лечения заболеваний интерфероном, характеризующиеся сниженными побочными эффектами |
| RU2222345C2 (ru) * | 2002-01-21 | 2004-01-27 | Волчек Игорь Анатольевич | Фармацевтическая композиция цитокинового и иммуномодулирующего действия |
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| US6348191B1 (en) * | 1986-07-08 | 2002-02-19 | Genetics Institute, Inc. | Production and use of IL-6 |
| IE67035B1 (en) * | 1986-07-08 | 1996-02-21 | Genetics Inst | Production and use of non-glycosylated IL-6 |
| US6284237B1 (en) * | 1986-07-08 | 2001-09-04 | Steven C. Clark | Methods of treatment using IL-6 |
| US5766582A (en) | 1994-10-11 | 1998-06-16 | Schering Corporation | Stable, aqueous alfa interferon solution formulations |
| TW426523B (en) | 1995-04-06 | 2001-03-21 | Hoffmann La Roche | Interferon solution |
| US5908621A (en) * | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| GB9609932D0 (en) * | 1996-05-13 | 1996-07-17 | Hoffmann La Roche | Use of IL-12 and IFN alpha for the treatment of infectious diseases |
| EP2298900A1 (en) * | 1996-09-17 | 2011-03-23 | Novartis Vaccines and Diagnostics, Inc. | Compositions and methods for treating intracellular diseases |
| TW589189B (en) * | 1997-08-04 | 2004-06-01 | Scras | Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis |
| JP2002532556A (ja) * | 1998-12-22 | 2002-10-02 | シェリング・コーポレーション | Ｃ型肝炎ウイルス感染のインターロイキン−１０での処置 |
| ES2200646B1 (es) * | 2001-09-21 | 2005-05-01 | Fundacion Para La Investigacion Medica Aplicada | Uso de la cardiotrofina en enfermedades hepaticas. |
| TW200408407A (en) * | 2001-11-30 | 2004-06-01 | Dana Farber Cancer Inst Inc | Methods and compositions for modulating the immune system and uses thereof |
| US20050027110A1 (en) * | 2003-07-24 | 2005-02-03 | Michael Russell | Drug delivery in the nervous system |
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| RU2128056C1 (ru) * | 1992-04-15 | 1999-03-27 | Амген Инк. | Способы и препараты для лечения заболеваний интерфероном, характеризующиеся сниженными побочными эффектами |
| EP0858343A1 (en) * | 1995-11-02 | 1998-08-19 | Schering Corporation | Continuous low-dose cytokine infusion therapy |
| RU2222345C2 (ru) * | 2002-01-21 | 2004-01-27 | Волчек Игорь Анатольевич | Фармацевтическая композиция цитокинового и иммуномодулирующего действия |
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| Patterson ВК, Tjernlund A, Andersson J. «Endogenous inhibitors of HIV: potent anti-HIV activity of leukemia inhibitory factor.», Curr Mol Med. 2002 Dec; 2(8):713-22. * |
| Цитокины и воспаление, том 1, №1, 2002, А.С.Симбирцев, стр.10, 16. * |
Also Published As
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| RU2008100307A (ru) | 2009-07-27 |
| US20090130055A1 (en) | 2009-05-21 |
| CA2612282A1 (en) | 2006-12-21 |
| JP5154412B2 (ja) | 2013-02-27 |
| WO2006134195A8 (es) | 2008-01-31 |
| BRPI0611988A2 (pt) | 2010-10-13 |
| CN101257918B (zh) | 2011-09-21 |
| WO2006134195A2 (es) | 2006-12-21 |
| EP1905447A4 (en) | 2012-04-25 |
| AU2006258966B2 (en) | 2011-11-17 |
| EP1905447A2 (en) | 2008-04-02 |
| ES2302402A1 (es) | 2008-07-01 |
| MX2007016060A (es) | 2008-03-10 |
| CN101257918A (zh) | 2008-09-03 |
| AU2006258966B8 (en) | 2011-12-08 |
| US7829077B2 (en) | 2010-11-09 |
| AU2006258966A1 (en) | 2006-12-21 |
| JP2008546672A (ja) | 2008-12-25 |
| WO2006134195A3 (es) | 2007-04-19 |
| US20110027224A1 (en) | 2011-02-03 |
| CA2612282C (en) | 2014-03-25 |
| ES2302402B1 (es) | 2009-05-08 |
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