RU2405459C2 - Device for treatment by subcutaneous supply of low pressure with application of flowing main and method connected with it - Google Patents

Device for treatment by subcutaneous supply of low pressure with application of flowing main and method connected with it Download PDF

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Publication number
RU2405459C2
RU2405459C2 RU2008136557/14A RU2008136557A RU2405459C2 RU 2405459 C2 RU2405459 C2 RU 2405459C2 RU 2008136557/14 A RU2008136557/14 A RU 2008136557/14A RU 2008136557 A RU2008136557 A RU 2008136557A RU 2405459 C2 RU2405459 C2 RU 2405459C2
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RU
Russia
Prior art keywords
tissue site
fluid
supply
fluid material
tissue
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Application number
RU2008136557/14A
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Russian (ru)
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RU2008136557A (en
Inventor
Ройс У. ДЖОНСОН (US)
Ройс У. Джонсон
Арчел А. АМБРОСИО (US)
Арчел А. АМБРОСИО
Ларри Д. СУЭЙН (US)
Ларри Д. СУЭЙН
Джоанна ПЭЙН (US)
Джоанна ПЭЙН
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КейСиАй Лайсензинг Инк.
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/92—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing with liquid supply means
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    • A61M2025/1086—Balloon catheters with special features or adapted for special applications having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves

Abstract

FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine and can be used for treatment of soft tissue wounds of various genesis. For this purpose claimed is device which includes tube of main supply, having passage and distal end, distal end being made for subcutaneous introduction and placement close to tissue section, and tube for supply of low pressure, made with possibility of flow connection with main stream canals. Distal end of tube of main supply is placed subcutaneously close to injured section of tissue with further supply through said tube of flowing material. Flowing material fills the cavity, located near tissue section, and thus forms main which has a lot of canals, which are in flow connection with injured section of tissue. Supply of low pressure is carried out through formed canals.
EFFECT: group of inventions ensures increase of efficiency of treatment of closed deep wounds due to possibility of bringing low pressure maximally close to difficult to access injured section.
28 cl, 1 tbl, 52 dwg

Description

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Claims (28)

1. Устройство подачи пониженного давления для лечения ткани путем подачи пониженного давления к участку ткани, содержащее
трубку подачи магистрали, имеющую проход и дистальный конец, причем дистальный конец выполнен для подкожного введения и размещения рядом с участком ткани;
текучий материал, выполненный с возможностью подкожной доставки через трубку подачи магистрали к ткани таким образом, чтобы текучий материал был способен к заполнению полости, расположенной рядом с участком ткани для создания магистрали, имеющей множество каналов потока в проточном сообщении с участком ткани; и
трубку подачи пониженного давления, выполненную с возможностью проточного сообщения с каналами потока магистрали.1. A reduced pressure supply device for treating tissue by supplying reduced pressure to a tissue site, comprising
a line feed tube having a passage and a distal end, the distal end being made for subcutaneous injection and placement near a tissue site;
fluid material adapted for subcutaneous delivery through the supply pipe to the tissue so that the fluid is capable of filling a cavity adjacent to the tissue site to create a line having multiple flow channels in fluid communication with the tissue site; and
a reduced pressure supply pipe configured to flow through communication with the main flow channels. 2. Устройство по п.1, в котором трубка подачи магистрали и трубка подачи пониженного давления является одной и той же трубкой.2. The device according to claim 1, in which the pipe supply line and the pipe supply low pressure is the same tube. 3. Устройство по п.1, в котором магистраль является саморассасывающейся.3. The device according to claim 1, in which the line is self-absorbable. 4. Устройство по п.1, в котором магистраль служит каркасом для роста ткани.4. The device according to claim 1, in which the trunk serves as a frame for tissue growth. 5. Устройство по п.1, в котором магистраль пенообразуется и отвердевает в присутствии по меньшей мере одного из физиологической жидкости и температуры тела.5. The device according to claim 1, in which the line is foamed and solidifies in the presence of at least one of physiological fluid and body temperature. 6. Устройство по п.1, в котором магистраль дополнительно содержит саморассасывающийся полимер, растворенный в растворителе и смешанный с бикарбонатом натрия и лимонной кислотой.6. The device according to claim 1, in which the line further comprises a self-absorbable polymer dissolved in a solvent and mixed with sodium bicarbonate and citric acid. 7. Устройство по п.6, в котором саморассасывающийся полимер представляет собой один из сополимеров полилактида и полиглюколида (PLAGA) и сополимер полиэтилен-гликоль-PLAGA.7. The device according to claim 6, in which the self-absorbable polymer is one of the copolymers of polylactide and polyglucolide (PLAGA) and a copolymer of polyethylene glycol-PLAGA. 8. Устройство по п.6, в котором растворитель представляет собой хлорид метилена.8. The device according to claim 6, in which the solvent is methylene chloride. 9. Устройство по п.1, в котором текучий материал выбран из группы, состоящей из жидкости, взвеси, суспензии, вязкого геля, пасты, замазки и твердых частиц.9. The device according to claim 1, in which the fluid material is selected from the group consisting of liquid, suspension, suspension, viscous gel, paste, putty and solid particles. 10. Устройство по п.1, в котором
текучий материал подвергается фазовому переходу в присутствии по меньшей мере одного из физиологической жидкости и температуры тела; и
текучий материал включает порообразователь, который растворяется с последующим отверждением текучего материала, причем растворение порообразователя создает множество каналов потока.10. The device according to claim 1, in which
the fluid material undergoes a phase transition in the presence of at least one of a physiological fluid and body temperature; and
the fluid material includes a blowing agent that dissolves, followed by solidification of the flowing material, the dissolution of the blowing agent creating many flow channels. 11. Устройство по п.1, в котором текучий материал содержит микросферы, имеющие покрытие, которое способно к выборочному сшиванию после подачи текучего материала к участку ткани.11. The device according to claim 1, in which the fluid material contains microspheres having a coating that is capable of selectively stitching after supplying the fluid material to the tissue site. 12. Устройство по п.11, в котором покрытие выборочно сшито под влиянием по меньшей мере одного из высокой температуры, света и химического соединения.12. The device according to claim 11, in which the coating is selectively crosslinked under the influence of at least one of high temperature, light and a chemical compound. 13. Устройство по п.11, в котором микросферы после сшивания создают множество каналов потока.13. The device according to claim 11, in which the microspheres after stitching create multiple flow channels. 14. Устройство по п.1, в котором
текучий материал выбран из группы пасты и замазки, имеющих начальную вязкость;
вязкость текучего материала уменьшается ниже начальной вязкости в присутствии сил сдвига во время его подачи к участку ткани; и
вязкость текучего материала возвращается к начальной вязкости после подачи текучего материала к участку ткани.14. The device according to claim 1, in which
the fluid material is selected from the group of pastes and putties having an initial viscosity;
the viscosity of the flowing material decreases below the initial viscosity in the presence of shear forces during its supply to the tissue site; and
the viscosity of the flowing material returns to the initial viscosity after supplying the flowing material to the tissue site. 15. Способ лечения путем подачи пониженного давления к участку ткани, включающий
подкожное размещение дистального конца трубы подачи магистрали рядом с участком ткани;
подкожную подачу текучего материала через трубку подачи магистрали к участку ткани, при этом текучий материал способен к заполнению полости, расположенной рядом с участком ткани, для создания магистрали, имеющей множество каналов потока, находящихся в проточном сообщении с участком ткани;
приложение пониженного давления к участку ткани через каналы потока магистрали.15. A method of treatment by applying reduced pressure to a tissue site, including
subcutaneous placement of the distal end of the supply pipe near the tissue site;
subcutaneous supply of fluid material through the supply pipe to the tissue site, while the fluid material is capable of filling a cavity located adjacent to the tissue site to create a line having multiple flow channels in fluid communication with the tissue site;
applying reduced pressure to the tissue site through the flow channels of the line. 16. Способ по п.15, в котором магистраль является саморассасывающейся.16. The method according to clause 15, in which the highway is self-absorbable. 17. Способ по п.15, в котором магистраль служит каркасом для роста ткани.17. The method according to clause 15, in which the trunk serves as a frame for tissue growth. 18. Способ по п.15, в котором магистраль вспенивают и подвергают фазовому переходу в присутствии по меньшей мере одного из физиологической жидкости и температуры тела.18. The method according to clause 15, in which the line is foamed and subjected to a phase transition in the presence of at least one of physiological fluid and body temperature. 19. Способ по п.18, в котором магистраль представляет собой термообратимый гель.19. The method according to p, in which the line is a thermally reversible gel. 20. Способ по п.15, в котором магистраль дополнительно содержит саморассасывающийся полимер, который растворяют в растворителе и смешивают с бикарбонатом натрия и лимонной кислотой.20. The method according to clause 15, in which the highway further comprises a self-absorbable polymer, which is dissolved in a solvent and mixed with sodium bicarbonate and citric acid. 21. Способ по п.20, в котором саморассасывающийся полимер представляет собой один из сополимера полилактида-сополиглюколида (PLAGA) и сополимера полиэтилен-гликоль-PLAGA.21. The method according to claim 20, in which the self-absorbable polymer is one of a polylactide copolyglucolide copolymer (PLAGA) and a polyethylene glycol-PLAGA copolymer. 22. Способ по п.18, в котором растворитель представляет собой хлорид метилена.22. The method according to p, in which the solvent is methylene chloride. 23. Способ по п.15, в котором текучий материал выбирают из группы, состоящей из жидкости, взвеси, суспензии, вязкого геля, пасты, замазки и твердых частиц.23. The method according to clause 15, in which the fluid material is selected from the group consisting of liquid, suspension, suspension, viscous gel, paste, putty and solid particles. 24. Способ по п.15, в котором
текучий материал подвергают фазовому переходу в присутствии по меньшей мере одного из физиологической жидкости и температуры тела; и
текучий материал содержит порообразователь, который
растворяют с последующим отверждением текучего материала, причем растворение порообразователя создает множество каналов потока.24. The method according to clause 15, in which
the fluid material undergoes a phase transition in the presence of at least one of a physiological fluid and body temperature; and
fluid material contains a blowing agent that
dissolved with the subsequent curing of the flowing material, and the dissolution of the blowing agent creates many flow channels. 25. Способ по п.15, в котором текучий материал содержит микросферы, имеющие покрытие, которое способно к выборочному сшиванию после подачи текучего материала к участку ткани.25. The method according to clause 15, in which the fluid material contains microspheres having a coating that is capable of selectively stitching after the flow of fluid material to the tissue site. 26. Способ по п.25, в котором покрытие выборочно сшивают под влиянием по меньшей мере одного из высокой температуры, света и химического соединения.26. The method according A.25, in which the coating is selectively stitched under the influence of at least one of high temperature, light and a chemical compound. 27. Способ по п.25, в котором микросферы после сшивания создают множество каналов потока.27. The method according A.25, in which the microspheres after stitching create many channels of the stream. 28. Способ по п.15, в котором
текучий материал выбирают из группы пасты и замазки, имеющей начальную вязкость;
вязкость текучего материала снижают ниже начальной вязкости в присутствии сил сдвига во время его подачи к участку ткани; и
вязкость текучего материала возвращают к начальной вязкости после подачи текучего материала к участку ткани. 28. The method according to clause 15, in which
the fluid material is selected from the group of paste and putty having an initial viscosity;
the viscosity of the flowing material is reduced below the initial viscosity in the presence of shear forces during its supply to the tissue site; and
the viscosity of the flowing material is returned to the initial viscosity after supplying the flowing material to the tissue site.
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