RU2316334C2 - Способ активации утраченных двигательных функций, а также определения эффективности их восстановления при повреждении центральной нервной системы - Google Patents
Способ активации утраченных двигательных функций, а также определения эффективности их восстановления при повреждении центральной нервной системы Download PDFInfo
- Publication number
- RU2316334C2 RU2316334C2 RU2005139565/15A RU2005139565A RU2316334C2 RU 2316334 C2 RU2316334 C2 RU 2316334C2 RU 2005139565/15 A RU2005139565/15 A RU 2005139565/15A RU 2005139565 A RU2005139565 A RU 2005139565A RU 2316334 C2 RU2316334 C2 RU 2316334C2
- Authority
- RU
- Russia
- Prior art keywords
- stimulation
- carried out
- injury
- patient
- elixir
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 42
- 230000007659 motor function Effects 0.000 title claims abstract description 32
- 230000003213 activating effect Effects 0.000 title claims description 11
- 210000003169 central nervous system Anatomy 0.000 title claims description 10
- 238000011084 recovery Methods 0.000 title claims description 7
- 208000001738 Nervous System Trauma Diseases 0.000 title 1
- 208000028412 nervous system injury Diseases 0.000 title 1
- 230000000638 stimulation Effects 0.000 claims abstract description 30
- 230000006378 damage Effects 0.000 claims abstract description 27
- 230000004044 response Effects 0.000 claims abstract description 19
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 18
- 208000014674 injury Diseases 0.000 claims abstract description 18
- 230000000035 biogenic effect Effects 0.000 claims abstract description 17
- 210000003414 extremity Anatomy 0.000 claims abstract description 16
- 210000003141 lower extremity Anatomy 0.000 claims abstract description 13
- 230000001537 neural effect Effects 0.000 claims abstract description 13
- 210000001087 myotubule Anatomy 0.000 claims abstract description 10
- 208000020431 spinal cord injury Diseases 0.000 claims abstract description 6
- 208000029028 brain injury Diseases 0.000 claims abstract description 5
- 210000001364 upper extremity Anatomy 0.000 claims abstract description 4
- 230000033001 locomotion Effects 0.000 claims description 27
- 230000011514 reflex Effects 0.000 claims description 13
- 238000000554 physical therapy Methods 0.000 claims description 11
- 230000006870 function Effects 0.000 claims description 10
- 239000007864 aqueous solution Substances 0.000 claims description 9
- 210000004126 nerve fiber Anatomy 0.000 claims description 8
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 7
- 241000207840 Jasminum Species 0.000 claims description 6
- 241001116389 Aloe Species 0.000 claims description 5
- 235000011399 aloe vera Nutrition 0.000 claims description 5
- 238000009434 installation Methods 0.000 claims description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 235000010254 Jasminum officinale Nutrition 0.000 claims description 4
- 241000241413 Propolis Species 0.000 claims description 4
- 239000006286 aqueous extract Substances 0.000 claims description 4
- 239000000284 extract Substances 0.000 claims description 4
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 4
- 229940069949 propolis Drugs 0.000 claims description 4
- 230000001143 conditioned effect Effects 0.000 claims description 3
- 210000003128 head Anatomy 0.000 claims description 3
- 239000000243 solution Substances 0.000 claims description 3
- 210000001508 eye Anatomy 0.000 claims description 2
- 238000012549 training Methods 0.000 claims description 2
- 230000001764 biostimulatory effect Effects 0.000 claims 1
- 238000005728 strengthening Methods 0.000 claims 1
- 210000005036 nerve Anatomy 0.000 abstract description 10
- 239000006185 dispersion Substances 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 5
- 239000003814 drug Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 210000002414 leg Anatomy 0.000 description 36
- 210000003205 muscle Anatomy 0.000 description 36
- 230000004913 activation Effects 0.000 description 24
- 230000001965 increasing effect Effects 0.000 description 15
- 210000004247 hand Anatomy 0.000 description 13
- 210000000278 spinal cord Anatomy 0.000 description 13
- 238000011161 development Methods 0.000 description 7
- 235000018102 proteins Nutrition 0.000 description 7
- 102000004169 proteins and genes Human genes 0.000 description 7
- 108090000623 proteins and genes Proteins 0.000 description 7
- 230000035945 sensitivity Effects 0.000 description 7
- 206010033885 Paraparesis Diseases 0.000 description 6
- 210000004556 brain Anatomy 0.000 description 6
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 6
- 210000003811 finger Anatomy 0.000 description 6
- 230000003902 lesion Effects 0.000 description 6
- 238000011160 research Methods 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 5
- 230000003247 decreasing effect Effects 0.000 description 5
- 238000003745 diagnosis Methods 0.000 description 5
- 210000002683 foot Anatomy 0.000 description 5
- 210000003127 knee Anatomy 0.000 description 5
- 230000000926 neurological effect Effects 0.000 description 5
- 102000003855 L-lactate dehydrogenase Human genes 0.000 description 4
- 108700023483 L-lactate dehydrogenases Proteins 0.000 description 4
- 230000036772 blood pressure Effects 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 210000000265 leukocyte Anatomy 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000001020 rhythmical effect Effects 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 102000009027 Albumins Human genes 0.000 description 3
- 108010088751 Albumins Proteins 0.000 description 3
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 3
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 3
- 102000008946 Fibrinogen Human genes 0.000 description 3
- 108010049003 Fibrinogen Proteins 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 206010033892 Paraplegia Diseases 0.000 description 3
- 238000008050 Total Bilirubin Reagent Methods 0.000 description 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 3
- 230000002776 aggregation Effects 0.000 description 3
- 238000004220 aggregation Methods 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 239000004202 carbamide Substances 0.000 description 3
- 229940109239 creatinine Drugs 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000000763 evoking effect Effects 0.000 description 3
- 230000005284 excitation Effects 0.000 description 3
- 229940012952 fibrinogen Drugs 0.000 description 3
- 230000004927 fusion Effects 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 210000001624 hip Anatomy 0.000 description 3
- 230000001771 impaired effect Effects 0.000 description 3
- 210000001503 joint Anatomy 0.000 description 3
- 210000000629 knee joint Anatomy 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 238000002559 palpation Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 210000002435 tendon Anatomy 0.000 description 3
- 230000000472 traumatic effect Effects 0.000 description 3
- 238000005353 urine analysis Methods 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 208000010392 Bone Fractures Diseases 0.000 description 2
- 208000034656 Contusions Diseases 0.000 description 2
- 206010017076 Fracture Diseases 0.000 description 2
- 241000489861 Maximus Species 0.000 description 2
- 206010033799 Paralysis Diseases 0.000 description 2
- 208000037656 Respiratory Sounds Diseases 0.000 description 2
- 208000002548 Spastic Paraparesis Diseases 0.000 description 2
- 206010046543 Urinary incontinence Diseases 0.000 description 2
- 206010047924 Wheezing Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000002146 bilateral effect Effects 0.000 description 2
- 210000005252 bulbus oculi Anatomy 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 230000004064 dysfunction Effects 0.000 description 2
- 210000001255 hallux Anatomy 0.000 description 2
- 230000002232 neuromuscular Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 208000021090 palsy Diseases 0.000 description 2
- 230000007170 pathology Effects 0.000 description 2
- 230000037361 pathway Effects 0.000 description 2
- 230000002980 postoperative effect Effects 0.000 description 2
- 230000000272 proprioceptive effect Effects 0.000 description 2
- 210000001747 pupil Anatomy 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 230000003238 somatosensory effect Effects 0.000 description 2
- 230000001148 spastic effect Effects 0.000 description 2
- 239000000021 stimulant Substances 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 206010009346 Clonus Diseases 0.000 description 1
- 208000024779 Comminuted Fractures Diseases 0.000 description 1
- 101800004637 Communis Proteins 0.000 description 1
- 101710173228 Glutathione hydrolase proenzyme Proteins 0.000 description 1
- 108010068370 Glutens Proteins 0.000 description 1
- 208000004044 Hypesthesia Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 206010027336 Menstruation delayed Diseases 0.000 description 1
- 241001094623 Mindarus obliquus Species 0.000 description 1
- 241000073666 Niganda radialis Species 0.000 description 1
- 241000012624 Nomada femoralis Species 0.000 description 1
- 241000458112 Nonarthra tibialis Species 0.000 description 1
- 208000010886 Peripheral nerve injury Diseases 0.000 description 1
- 241001272996 Polyphylla fullo Species 0.000 description 1
- 206010039203 Road traffic accident Diseases 0.000 description 1
- 208000029033 Spinal Cord disease Diseases 0.000 description 1
- 206010047571 Visual impairment Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 210000000544 articulatio talocruralis Anatomy 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 238000004820 blood count Methods 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000006931 brain damage Effects 0.000 description 1
- 231100000874 brain damage Toxicity 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 210000001217 buttock Anatomy 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- 238000004590 computer program Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 208000006111 contracture Diseases 0.000 description 1
- 230000009519 contusion Effects 0.000 description 1
- 210000003792 cranial nerve Anatomy 0.000 description 1
- 210000000852 deltoid muscle Anatomy 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 210000002310 elbow joint Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000009207 exercise therapy Methods 0.000 description 1
- 210000003099 femoral nerve Anatomy 0.000 description 1
- 239000000834 fixative Substances 0.000 description 1
- FVTCRASFADXXNN-SCRDCRAPSA-N flavin mononucleotide Chemical compound OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O FVTCRASFADXXNN-SCRDCRAPSA-N 0.000 description 1
- WGXUDTHMEITUBO-YFKPBYRVSA-N glutaurine Chemical compound OC(=O)[C@@H](N)CCC(=O)NCCS(O)(=O)=O WGXUDTHMEITUBO-YFKPBYRVSA-N 0.000 description 1
- 235000021312 gluten Nutrition 0.000 description 1
- 210000004394 hip joint Anatomy 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 208000034783 hypoesthesia Diseases 0.000 description 1
- 210000001621 ilium bone Anatomy 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000007915 intraurethral administration Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 210000001617 median nerve Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000004118 muscle contraction Effects 0.000 description 1
- 230000007830 nerve conduction Effects 0.000 description 1
- 230000036403 neuro physiology Effects 0.000 description 1
- 230000001272 neurogenic effect Effects 0.000 description 1
- 230000007171 neuropathology Effects 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 206010029864 nystagmus Diseases 0.000 description 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 description 1
- 208000035824 paresthesia Diseases 0.000 description 1
- 210000004417 patella Anatomy 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 210000000578 peripheral nerve Anatomy 0.000 description 1
- 210000001428 peripheral nervous system Anatomy 0.000 description 1
- 210000004345 peroneal nerve Anatomy 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 210000002979 radial nerve Anatomy 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000036387 respiratory rate Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 210000004003 subcutaneous fat Anatomy 0.000 description 1
- 238000011477 surgical intervention Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 210000002972 tibial nerve Anatomy 0.000 description 1
- 210000003371 toe Anatomy 0.000 description 1
- 238000011491 transcranial magnetic stimulation Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 210000003901 trigeminal nerve Anatomy 0.000 description 1
- 230000001228 trophic effect Effects 0.000 description 1
- 210000000658 ulnar nerve Anatomy 0.000 description 1
- 230000003202 urodynamic effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/388—Nerve conduction study, e.g. detecting action potential of peripheral nerves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
- A61B5/407—Evaluating the spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
- A61B5/4064—Evaluating the brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/416—Evaluating particular organs or parts of the immune or lymphatic systems the spleen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Medical Informatics (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Insects & Arthropods (AREA)
- Neurosurgery (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Animal Husbandry (AREA)
- Radiology & Medical Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Zoology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physiology (AREA)
- Finger-Pressure Massage (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Electrotherapy Devices (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2005139565/15A RU2316334C2 (ru) | 2005-12-19 | 2005-12-19 | Способ активации утраченных двигательных функций, а также определения эффективности их восстановления при повреждении центральной нервной системы |
| PCT/EP2006/009009 WO2007071295A1 (fr) | 2005-12-19 | 2006-09-15 | Méthode pour activer des fonctions perdues de mouvement et définir une performance efficace de récupération en rapport avec les lésions du système nerveux central |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2005139565/15A RU2316334C2 (ru) | 2005-12-19 | 2005-12-19 | Способ активации утраченных двигательных функций, а также определения эффективности их восстановления при повреждении центральной нервной системы |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007130238/14A Division RU2007130238A (ru) | 2007-08-07 | 2007-08-07 | Способ активации утраченных двигательных функций, а также определения эффективности их восстановления при повреждении центральной нервной системы |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2005139565A RU2005139565A (ru) | 2007-06-27 |
| RU2316334C2 true RU2316334C2 (ru) | 2008-02-10 |
Family
ID=37685249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2005139565/15A RU2316334C2 (ru) | 2005-12-19 | 2005-12-19 | Способ активации утраченных двигательных функций, а также определения эффективности их восстановления при повреждении центральной нервной системы |
Country Status (2)
| Country | Link |
|---|---|
| RU (1) | RU2316334C2 (fr) |
| WO (1) | WO2007071295A1 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011142691A2 (fr) | 2010-04-06 | 2011-11-17 | ГОСУДАРСТВЕННОЕ ОБРАЗОВАТЕЛЬНОЕ УЧРЕЖДЕНИЕ ВЫСШЕГО ПРОФЕССИОНАЛЬНОГО ОБРАЗОВАНИЯ "КРАСНОЯРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ ПРОФЕССОРА В. Ф. ВОИНО-ЯСЕНЕЦКОГд МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ И СОЦИАЛЬНОГО РАЗВИТИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ" | Procédé de production d'une matrice neuronale |
| RU2504329C1 (ru) * | 2012-10-02 | 2014-01-20 | Федеральное государственное бюджетное учреждение "Научный центр неврологии" Российской академии медицинских наук | Способ выявления в коре головного мозга сенсомоторных зон, ответственных за локомоцию |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1759001E (pt) | 2004-04-21 | 2011-07-12 | Enobia Pharma Inc | Conjugados de libertação óssea e método de utilização dos mesmos para direccionar proteínas ao osso |
| US7969243B2 (en) | 2009-04-22 | 2011-06-28 | Acco Semiconductor, Inc. | Electronic circuits including a MOSFET and a dual-gate JFET |
| WO2016007873A1 (fr) | 2014-07-11 | 2016-01-14 | The Regents Of The University Of Michigan | Compositions et méthodes de traitement de la craniosynostose |
| EP3226891A1 (fr) | 2014-12-05 | 2017-10-11 | Alexion Pharmaceuticals, Inc. | Traitement de crise avec une phosphatase alcaline recombinée |
| JP6868561B2 (ja) | 2015-01-28 | 2021-05-12 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | アルカリホスファターゼ欠損を有する被験者を治療する方法 |
| KR102644116B1 (ko) | 2015-08-17 | 2024-03-05 | 알렉시온 파마슈티칼스, 인코포레이티드 | 알칼린 포스파타제의 제조 |
| JP6868617B2 (ja) | 2015-09-28 | 2021-05-12 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 低ホスファターゼ血症の組織非特異的アルカリホスファターゼ（ｔｎｓａｌｐ）酵素補充療法に有効な投薬計画の特定 |
| WO2017074466A1 (fr) | 2015-10-30 | 2017-05-04 | Alexion Pharmaceuticals, Inc. | Méthodes de traitement de la craniosynostose chez un patient |
| US11065306B2 (en) | 2016-03-08 | 2021-07-20 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in children |
| WO2017173395A1 (fr) | 2016-04-01 | 2017-10-05 | Alexion Pharmaceuticals, Inc. | Méthodes de traitement de l'hypophosphatasie chez les adolescents et les adultes |
| JP2019513711A (ja) * | 2016-04-01 | 2019-05-30 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | アルカリホスファターゼによって筋力低下を治療すること |
| US10988744B2 (en) | 2016-06-06 | 2021-04-27 | Alexion Pharmaceuticals, Inc. | Method of producing alkaline phosphatase |
| EP3500289A4 (fr) | 2016-08-18 | 2020-05-06 | Alexion Pharmaceuticals, Inc. | Procédés de traitement de la trachéobronchomalacie |
| CN110719786A (zh) | 2017-03-31 | 2020-01-21 | 阿雷克森制药公司 | 用于治疗成人和青少年的低磷酸酯酶症(hpp)的方法 |
| WO2019190752A1 (fr) | 2018-03-30 | 2019-10-03 | Alexion Pharmaceuticals, Inc. | Production de glycoprotéines |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT406731B (de) * | 1998-04-24 | 2000-08-25 | Dado Suleiman | Stoffgemisch zur topischen anwendung |
| US6596266B2 (en) * | 2000-02-18 | 2003-07-22 | Natural Science, Inc. | Compositions containing minoxidil and saw palmetto for treating baldness |
-
2005
- 2005-12-19 RU RU2005139565/15A patent/RU2316334C2/ru not_active IP Right Cessation
-
2006
- 2006-09-15 WO PCT/EP2006/009009 patent/WO2007071295A1/fr active Application Filing
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011142691A2 (fr) | 2010-04-06 | 2011-11-17 | ГОСУДАРСТВЕННОЕ ОБРАЗОВАТЕЛЬНОЕ УЧРЕЖДЕНИЕ ВЫСШЕГО ПРОФЕССИОНАЛЬНОГО ОБРАЗОВАНИЯ "КРАСНОЯРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ ПРОФЕССОРА В. Ф. ВОИНО-ЯСЕНЕЦКОГд МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ И СОЦИАЛЬНОГО РАЗВИТИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ" | Procédé de production d'une matrice neuronale |
| RU2504329C1 (ru) * | 2012-10-02 | 2014-01-20 | Федеральное государственное бюджетное учреждение "Научный центр неврологии" Российской академии медицинских наук | Способ выявления в коре головного мозга сенсомоторных зон, ответственных за локомоцию |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2005139565A (ru) | 2007-06-27 |
| WO2007071295A1 (fr) | 2007-06-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2316334C2 (ru) | Способ активации утраченных двигательных функций, а также определения эффективности их восстановления при повреждении центральной нервной системы | |
| JP2013512709A (ja) | 痙性筋肉の筋肉弛緩のためのシステムおよび装着具 | |
| Mahmood et al. | Special exercises for some physical, kinetic and electrical abilities accompanied by symmetrical electrical stimulation in the rehabilitation of the muscles of the legs for patients with simple hemiplegic cerebral palsy | |
| Hwang et al. | Treadmill training with tilt sensor functional electrical stimulation for improving balance, gait, and muscle architecture of tibialis anterior of survivors with chronic stroke: A randomized controlled trial | |
| Baek et al. | Effects of repetitive peripheral magnetic stimulation over vastus lateralis in patients after hip replacement surgery | |
| RU2296550C1 (ru) | Способ оздоровления пациента с использованием остеопатических приемов по методу доктора артёмова | |
| RU2119788C1 (ru) | Способ восстановления функций периферических нервов | |
| RU2236264C1 (ru) | Способ формирования вертикальной позы у больных с нарушением проводимости по спинному мозгу | |
| Stępnik et al. | Assessment of the effects of manual techniques on neck pain. | |
| RU2122443C1 (ru) | Способ коррекции нервно-психических заболеваний, сопровождающихся двигательными нарушениями | |
| RU2350359C2 (ru) | Способ лечения детей с последствиями перинатального поражения центральной нервной системы с помощью аппарата "лимфавижин" | |
| Pishnamazi | Case study of Physiotherapy Treatment of a patient with poly trauma of the right upper extremity | |
| RU2800245C2 (ru) | Способ реабилитации пациентов с хондропатией бугристости большеберцовой кости | |
| RU2813807C1 (ru) | Способ мультимодальной коррекции двигательных и когнитивных нарушений у пациентов, перенесших ишемический инсульт | |
| RU2246329C1 (ru) | Способ активной динамической электростимуляции мышц конечностей | |
| Watkins | Practical applications of progressive resistance exercises | |
| Bartáková | Case Study of Physiotherapeutic Treatment of a Patient with Systemic Sclerosis | |
| SU1630837A1 (ru) | Способ реабилитации больных с демиелинизирующими двигательными нейропати ми | |
| Kumar et al. | Fundamental of Physiotherapy | |
| Elmehrath et al. | Effect of modified hand position during circuit resistance training on improving shoulder kinematics in paraplegic patients | |
| Danylova | Case Study of Physiotherapeutic Treatment of a Patient after the Surgical Intervention for Closed Proximal Humerus Fracture | |
| RU2339358C2 (ru) | Способ терапии | |
| SADEGHI | Treatment rehabilitation plan and procedure in patients with algic spine syndrome | |
| D'Isanto | Sport adapted hippotherapy for disabled people affected by multiple sclerosis | |
| RU2236209C1 (ru) | Способ восстановления вертикальной позы у больных с нарушением проводимости по спинному мозгу |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20081220 |