RU2315613C1 - Agent "grepol-c" and method for its using in hypothyroidism - Google Patents

Abstract

FIELD: medicine, endocrinology, chemical-pharmaceutical industry, pharmacy.

SUBSTANCE: invention relates to design of agent used in treatment of iodine-deficient diseases, in particular, hypothyroidism. Agent for treatment of hypothyroidism comprises the following medicinal plants: walnut green fruits, wormwood herb, warty birch buds, licorice roots and clove flower buds taken in the ratio = 30:2:10:2:2, respectively. Agent is prepared as tincture in 35% ethyl alcohol. Method for treatment of hypothyroidism involves prescription of abovementioned agent to a patient orally in the dose 7-30 drops, 3 times per a day, 15 min before eating with 50 ml of water for 5-35 days. In all cases treatment of patients with the proposed agent resulted to the stable therapeutic effect without adverse effects.

EFFECT: valuable medicinal properties of agent.

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Description

The invention relates to medicine, namely to the creation of an agent for the treatment of iodine deficiency diseases, in particular hypothyroidism.

In the mechanism of formation of iodine deficiency states, a certain role is played by the combined effect of various factors: natural iodine deficiency, microelement imbalance, toxic chemical load, immune disorders, etc.

Non-correctable iodine deficiency against the background of severe anthropogenic pollution of the atmosphere, water, food is one of the main causes of tension and severity of goiter endemic.

It is known the use of drugs (levothyroxine, lyotrix, etc.) in the treatment of hypothyroidism (Bezdenezhnaya LP, Bezenezhnaya TI The thyroid gland: diagnosis, treatment, disease prevention. - Rostov on Don. - 2004).

However, the known drugs when used internally cause increased irritability, irritability, constant replacement therapy is required (Sokolov S.Ya., Zamotaev I.P. Medicinal plants: Handbook. - M., 1984).

The objective of the invention is to increase the effectiveness of the treatment of hypothyroidism and eliminate the above negative aspects when using them.

The problem is solved by creating a composition of domestic plant materials with anti-inflammatory, antiseptic, anti-allergic, hormone-regulating effect.

The essence of the invention lies in the fact that the proposed tool for the treatment of hypothyroidism includes medicinal plants: green fruits of walnuts, wormwood, buds of warty birch, licorice roots and clove buds at a ratio of 30: 2: 10: 2: 2, while it is made in the form of tincture on 35% ethyl alcohol.

A method is also proposed for the treatment of hypothyroidism, which consists in the fact that the patient is prescribed the above-mentioned agent inside at a dose of 7-30 drops 3 times a day 15 minutes before meals with 50 ml of water for 5-35 days.

The basic components of the drug include the following, affecting the cause and mechanism of the development of the disease and having pharmacodynamic properties.

Walnut is a deciduous tree of the walnut family. A complex of vitamins, carotene, quinones, which have bactericidal, anti-inflammatory and hormone-regulating properties, are found in green fruits. The positive effect of pericarp and green fruit on the thyroid gland has been known since the time of Hippocrates (Pastushenkov L.V. et al. Medicinal plants. - L., 1990).

Wormwood is a perennial wild plant. It has anti-inflammatory, hormone-regulating, calming, antispasmodic effects. When injected, it stimulates the activity of the digestive glands, has a regulatory effect on the functioning of the hypothalamic-pituitary structures (Ivanchenko V.A. Phytoergonomics. - Kiev, 1989), has a normalizing effect on the function of the thyroid gland.

Warty birch is a well-known tree. Birch buds contain an essential oil containing betulinic acid, betulinol, which exhibit antiseptic, anti-inflammatory, hormone-regulating effects due to the presence of triterpenoids, etc. (Korsun V.F. et al. Medicinal plants in hepatology. - M., 2005).

Clove, clove tree is a spicy-aromatic plant, mature buds have long been a spice containing up to 20% tannins, up to 20% essential clove oil, the main component of which is eugenol (Barnaulov O.D. Phytotherapy for patients with pulmonary tuberculosis. - St. Petersburg, 1999). Modern researchers attribute the essential oil and the infusion of buds as a highly effective antiseptic agent (Choi Tesop. Medicinal plants. / Transl. From Korean. - M., 1987), which improves the thyroid gland.

The tool is prepared in the usual way, widely used in pharmacy in the preparation of tinctures. Pre-crushed dried raw materials are taken in the indicated proportions and mixed, then they are poured with 35% ethanol at a ratio of raw materials: extractant 1:10, respectively. Insist in a dark place, then filter.

Treatment should begin at any period of the disease.

A decrease in the manifestations of the disease occurs after 5-15 days.

The invention is illustrated by the following examples.

Example 1. Patient K., 28 years old, technologist. Complains of weakness, nausea, weight loss. I was observed by an endocrinologist about hypothyroidism, underwent twice outpatient treatment with temporary success. Constantly takes L-thyroxine at a dose of 100 mg 3 times a day. Recently noted irritability, tearfulness, poor sleep. I took a course of taking grepol - C, 30 drops 3 times a day before meals for 35 days. After the course of treatment noted the disappearance of irritability, normalized sleep, appetite. I added 2.5 kg in body weight. Repeated analysis of the level of thyroid hormones showed a tendency to normalize them.

Example 2. There were 14 patients with hypothyroidism, most often women aged 25-46 years. The diagnosis of the disease was made on the basis of clinical data, measurement of the level of thyroid hormones, ultrasound of the thyroid gland and consultation with an endocrinologist. All patients were prescribed grepol-C (with their consent) 1 ml 3 times a day with 50 ml of water 15 minutes before meals for 1.5 months. After 2.5 months from the start of treatment, the patients underwent re-examination and consultation with an endocrinologist. According to his conclusion, there is a tendency to normalize the levels of thyroxine and triiodothyronine, as well as a decrease in the size of the thyroid gland. All patients tolerated the drug well, without any side effects.

In all cases, treatment with the indicated agent led to a lasting therapeutic effect.

Claims (2)

1. An agent for the treatment of hypothyroidism, characterized in that it includes medicinal plants: green walnut fruits, bitter wormwood grass, warty birch buds, licorice roots and clove buds at a ratio of 30: 2: 10: 2: 2, while it is made in the form of tincture with 35% ethanol. 2. A method of treating hypothyroidism, characterized in that the patient is prescribed inside the drug according to claim 1 at a dose of 7-30 drops 3 times a day 15 minutes before meals with 50 ml of water for 5-35 days.