RU2304980C2 - Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды pai-1 - Google Patents

Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды pai-1 Download PDF

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Publication number
RU2304980C2
RU2304980C2 RU2004117535/15A RU2004117535A RU2304980C2 RU 2304980 C2 RU2304980 C2 RU 2304980C2 RU 2004117535/15 A RU2004117535/15 A RU 2004117535/15A RU 2004117535 A RU2004117535 A RU 2004117535A RU 2304980 C2 RU2304980 C2 RU 2304980C2
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RU
Russia
Prior art keywords
pai
factor vii
polypeptide
factor
preparation
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RU2004117535/15A
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English (en)
Russian (ru)
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RU2004117535A (ru
Inventor
Расмус РЕЙКЕР (DK)
Расмус РЕЙКЕР
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Ново Нордиск Хелт Кэр Аг
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Publication of RU2004117535A publication Critical patent/RU2004117535A/ru
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Publication of RU2304980C2 publication Critical patent/RU2304980C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU2004117535/15A 2001-11-09 2002-11-05 Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды pai-1 RU2304980C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101671 2001-11-09
DKPA200101671 2001-11-09

Publications (2)

Publication Number Publication Date
RU2004117535A RU2004117535A (ru) 2005-04-10
RU2304980C2 true RU2304980C2 (ru) 2007-08-27

Family

ID=8160829

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004117535/15A RU2304980C2 (ru) 2001-11-09 2002-11-05 Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды pai-1

Country Status (15)

Country Link
EP (1) EP1446146A1 (pt)
JP (1) JP2005510514A (pt)
KR (1) KR20050043733A (pt)
CN (1) CN1596122A (pt)
AU (1) AU2002340778B2 (pt)
BR (1) BR0213952A (pt)
CA (1) CA2464614A1 (pt)
CZ (1) CZ2004535A3 (pt)
HU (1) HUP0401959A3 (pt)
IL (1) IL161523A0 (pt)
NO (1) NO20042379L (pt)
PL (1) PL370118A1 (pt)
RU (1) RU2304980C2 (pt)
WO (1) WO2003039580A1 (pt)
ZA (1) ZA200403270B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009045412A2 (en) * 2007-10-01 2009-04-09 American Diagnostica, Inc. Methods of treatment using modified plasminogen activator inhibitor type-1 molecules
CN111205244B (zh) * 2018-11-22 2023-08-18 上海科技大学 噻唑并环类化合物、其制备方法、中间体和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7907398A (en) * 1997-06-23 1999-01-04 Novo Nordisk A/S Use of fviia for the treatment of bleedings in patients with a normal blood clotting cascade and normal platelet function
AT409335B (de) * 1998-11-10 2002-07-25 Immuno Ag Pharmazeutisches präparat enthaltend einen rezeptor-antagonisten zur behandlung von blutgerinnungsstörungen
EP1282693B1 (en) * 2000-05-03 2010-10-20 Novo Nordisk Health Care AG Human coagulation factor vii variants

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TORBET J. The trombin activation pathway modulates the assembly, structure and lysis of human plasma clots in vitro. Thromb. Haemost., 1995, May, v.73(5), p.785-792. *

Also Published As

Publication number Publication date
AU2002340778B2 (en) 2007-08-02
PL370118A1 (en) 2005-05-16
CA2464614A1 (en) 2003-05-15
NO20042379L (no) 2004-06-08
HUP0401959A2 (hu) 2004-12-28
KR20050043733A (ko) 2005-05-11
CN1596122A (zh) 2005-03-16
ZA200403270B (en) 2004-11-08
WO2003039580A1 (en) 2003-05-15
CZ2004535A3 (cs) 2005-01-12
HUP0401959A3 (en) 2009-03-30
RU2004117535A (ru) 2005-04-10
JP2005510514A (ja) 2005-04-21
IL161523A0 (en) 2004-09-27
BR0213952A (pt) 2004-08-31
EP1446146A1 (en) 2004-08-18

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20081106