RU2295989C2 - Method for controlling physical and psychoemotional status of the persons being in desynchronosis condition - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: method involves simultaneously treating patient eye retina with artificial light in various spectral ranges in an interval of 360 - 380 nm and 390 - 680 nm with intensity of 0.04-0.5 W/m².

EFFECT: enhanced effectiveness of treatment.

Description

The invention relates to physiotherapy and is intended for the treatment and correction of the condition of people, denoted in the literature as “desynchronosis”. Desynchronosis is called “disorganization of the circadian system” of regulation of the rhythms of the physiological functions of the human body (2; 4, p. 7-37). Signs of desynchronosis: disturbances of falling asleep, night awakenings, restless sleep, early awakening, daytime drowsiness, appetite disorders, changes in eating patterns, decreased performance, lethargy, irritability, decreased mood, disturbance of the daily rhythm of body temperature, as well as other phenomenological and laboratory manifestations (8 ; 13). This condition can be etiopathogenetically associated with night work (7), rapid transmeridional movements (10), geographical conditions of residence and / or work (1), as well as a number of other factors (18; 5). Of particular relevance is the problem of desynchronosis in medical practice (12; 19, etc.). The method can be used to increase the physical and mental performance of personnel in the workplace, to eliminate night drowsiness, regulate a person’s emotional state, create a subjective feeling of comfort, increase a person’s motivational stress, regulate alcohol consumption, and prevent premenstrual stress syndrome. The method makes it possible to influence the physical and psycho-emotional state of a person in other cases.

Known methods of exposure to light, based on a single-component exposure or in combination with other physiotherapeutic procedures for psychopathological symptoms (6).

The disadvantages of these methods include: the use of exposure in a limited part of the spectrum (p. No. 1766424), the effect on peripheral biological tissues (p. No. 2039580, p. No. 1697854), the indirect effect on the etiopathogenetic links of the disease process (p. No. 206357, p. No. 1827271).

A significant drawback of these methods is the therapeutic focus, which limits their use to the contingent of patients with nosologically verified diagnoses. Meanwhile, the imperfection of statistical diagnostic classifications assumes a difference in qualifying features. Thus, ICD-10 (International Classification of Diseases), unlike DSM-IV (American Diagnostic Manual), does not single out “seasonal affective disorder”, which undoubtedly is a clinical reality, in its independent diagnostic section (11). In addition, the disorders under consideration may not be of a painful nature at all, but rather be part of the body's adaptive response structure (15).

The closest biological and medical essence to the invention is a method of exposure to light in the UVA range of 360-370 nm, with an intensity of 0.04-0.3 W / m ² on the patient’s retina in order to stop psychopathological symptoms - Patent RU No. 2134137 effective March 11, 1998.

The implementation of the prototype method is based on the action of ultraviolet radiation in the range of 360-370 nm, on the retina, with the aim of resynchronizing the rhythm-organizing structures of the brain (9; 16, p. 65-66).

The disadvantages of the prototype method are the low efficiency of treatment, since the effect is carried out only in the spectral range of 360-370 nm and the orientation on the contingent of patients with a diagnosis of seasonal affective disorder. The first of these drawbacks is associated with the limited use of the spectral continuum with a very narrow zone of the long-wavelength “near” ultraviolet (UV-A), which does not correspond to the theoretical recommendations “use full-spectrum light” (6). In addition, the isolated use of long-wave ultraviolet radiation limits the radiation intensity to the declared range (0.04-0.3 W / m ² ), which does not correspond to the proportion of ultraviolet radiation in the composition of even diffused sunlight. The indicated intensity restriction was introduced taking into account the safety standards adopted by the World Health Organization (17, p. 51-95) for isolated ultraviolet radiation and undoubtedly reduces both the synchronizing and stimulating effects of exposure. At the same time, it is known that the damaging effect of isolated ultraviolet light is much higher than in the full-spectrum radiation flux (sunlight). The neutralizing effect of the optical parts of the spectrum on the ultraviolet component damaging the ocular media is also preserved in artificial light sources (14, p. 24), allowing them to increase their efficiency by approaching the ratio of intensities of individual parts of the spectrum in sunlight. The enrichment of optical radiation with long-wave ultraviolet, recreating the structure of natural sunlight, in part of the Fraunhofer lines (3, p. 21) makes it possible to reduce the intensity of optical radiation used in phototherapeutic installations, which is also capable of causing damage to ocular environments, in recommended doses.

The purpose of the invention is to increase the effectiveness of light therapy, reduce treatment time, expand the functionality of the method of treatment and correction of the physical and psycho-emotional state of people associated with heliogeophysical factors (decrease in duration, intensity and other natural lighting).

This goal is achieved by the simultaneous additional exposure to artificial retina in the spectral range of 390-680 nm on the human retina.

The essence of the invention lies in light exposure simulating the structure of natural sunlight (spectral regions of the visible and long-wave ultraviolet radiation) on the retina of the human eye.

Comparison of the proposed method with other known in the field of medicine, showed its compliance with the criteria of the invention.

The method is as follows.

The patient is located at a distance of 1-3 meters from 4-10 working light sources, the height of the lamps is 0.5-1.5 m above the floor. Electroluminescent or incandescent lamps emitting visible light (390-680 nm) and lamps emitting in the range of 360-380 nm are used. Can be used, for example, LB-80, LD-80, LBC 60, LDTSUF-80 and "PHILIPS" -L / 73 and similar light sources. Depending on the technical characteristics of a particular brand, the number of light sources can vary (from 4 to 10), and the radiation intensity and illumination also vary. The main acting factor - the combination of radiation in various spectral zones (360-380 nm and 390-680 nm) remains constant. At this location, the intensity of ultraviolet radiation at the level of the patient’s external ocular environments is from 0.04 W / m ² to 0.5 W / m ² . Illumination by visible light is about 1500-4000 lux. The duration of the session is from 20 minutes to 3 hours. Accordingly, the exposure dose of ultraviolet radiation per session ranges from 200 J / m ² to 10,000 J / m ² , remaining within the recommended safe level. The course includes 6-18 daily sessions.

Examples of the method.

Example 1. Patient B-in, 36 years old. It works on a rotational basis, flies to the north of the Tyumen region every 3 weeks. Somatically healthy. The last 2 months he complains of poor sleep, frequent awakenings at night, distraction, inability to concentrate, a “heavy” sensation in the head, and decreased working capacity. In status - a subclinical decline in mood, a pessimistic assessment of their abilities, prospects for the future; sleep disorders, confirmed by polysomnography. He took an outpatient correction course for 8 days, in the evening-twilight time. The duration of the sessions is 40-60 minutes. Light sources: 1 lamp “PHILIPS” L / 73, 5 lamps LB-80 and 2 lamps LD-80. The patient was located 1.5 meters from light sources. Illumination is about 2500 lux, the intensity of long-wave ultraviolet light is 0.08-0.2 W / m ² . At the end of the course, night sleep returned to normal (the latent period of the paradoxical phase of sleep was restored, the number of interstage transitions decreased), daytime lethargy disappeared, and he began to attend cultural events with the family. After 2 months, she assesses the effect of phototherapy as stable positive.

Example 2. Patient K-va, 44 years old. She was hospitalized in a psychiatric hospital, in connection with complaints of reduced, depressed mood, depression, apathy, motor lethargy. A history of several hospitalizations, treatment with antidepressants. I visited 10 sessions of phototherapy according to the specified method. The duration of the sessions is 1-1.5 hours. Light sources: 1 lamp “PHILIPS” L / 73 and from 3 to 7 lamps LD-80 and LB-80. Illumination is 1500-3000 lux, the intensity of ultraviolet light is 0.1-0.2 W / m ² . There is a significant positive dynamics of the state associated with a reduction in psychopathological symptoms. A few years ago I attended sessions of phototherapy according to the prototype method, a slight effect was noted for 18 sessions.

INFORMATION SOURCES

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Claims (1)

A method of regulating the physical and psychoemotional status of persons in a state of desynchronosis, including exposure to artificial retina on the human eye, characterized in that they simultaneously act in different spectral ranges in the range of 360-380 nm and 390-680 nm with an intensity of 0.04-0 5 W / m ² .