RU2274430C1 - Method for treating dogs for regenerating wounds - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: method involves treating biologically active points with alternating pulsating current and placing drug on wound surface. Acting current has frequency of 30 Hz and intensity of 50 mcA. The following treatment routine is applied: +28 s/-4 s with cycle number equal to 2 during the first-third day, 32 s x 2=64 s; +4 s/-4 s with cycle number equal to 2 during the fourth-fifth day, 8 s x 2=16 s; +28 s/-4 s with cycle number equal to 2 during the sixth-tenth day, 32 s x 2=64 s, where time in seconds on active electrode is +/, and is - on the passive one. Biologically active points like V 2, IG 2, V 4, IG 5, F 13, R 5, IG 17 are selected. Traumehl ointment is applied as the drug. Echinacea compositum solution is additionally introduced in the amount of 1 ml at the first day; 2 ml at the second and third day; 4 ml at the fourth and fifth day; the sixth and seventh day are omitted; 4 ml at the eighth day, 2 ml at the ninth day; 1 ml at the tenth day. Traumehl solution is intramuscularly introduced at a dose of 5 ml once a day. Treatment with alternating pulsating current is applied by means of multi-functional apparatus for carrying out electroreflexogenic therapy.

EFFECT: reduced risk of complications.

2 cl, 1 dwg

Description

The invention relates to veterinary surgery and can be used to treat regenerative wounds in dogs with alternative medicine with an extensive lesion area, large wound cavity, severe gaping and when the defect cannot be closed with sutures.

There is a method of treatment in which a balsamic liniment is applied directly to the wound surface according to A.V. Vishnevsky (General Veterinary Surgery. - A.V. Lebedev, V.A. Lukyanovsky, B.S. Semenov. - 2000. - 156 p. )

The disadvantages of using liniment according to A.V. Vishnevsky in the treatment of regenerative wounds are due to the fact that liniment is a liquid ointment that, after application to the wound, partially follows from it, therefore, the effect of the drug is not dosed. The xeroform powder included in the liniment does not dissolve in fish oil. When applied to the wound surface is distributed unevenly. As a result, granulation tissue does not grow over the entire surface of the wound, but islets. The granulations themselves are hydremic, coarse-grained, red, sometimes bleeding, due to redistribution caused by birch tar. The formation of the demarcation shaft is delayed. Conditions are created for contact with microbes and the development of surgical infection. It has an immunosuppressive effect, the use causes an allergic reaction. The daily surgical treatment of wounds and the introduction into the wound cavity are painful for animals, which creates difficulties in their fixation and the appearance of mental trauma during subsequent manipulations. Especially aggressive animals along with painkillers are used sedatives and muscle relaxants (prevention of traumatic shock).

There is a treatment method in which, in order to prevent the development of surgical infection, the antibiotic bicillin-3 is administered intramuscularly (General Veterinary Surgery. - A.V. Lebedev, V.A. Lukyanovsky, B.S. Semenov. - 2000. - 155 p.) .

The disadvantages of this method are increased individual sensitivity, the development of allergic reactions, local irritant effect, inhibition of general immunity.

A known treatment method in which to stimulate the growth of granulation is used ultrashort-wave (ultra-high frequency - UHF) therapy (General Veterinary Surgery. - A.V. Lebedev, V.A. Lukyanovsky, B.S. Semenov. - 2000. - 157 p.) .

Disadvantages of application of UHF-therapy in the treatment process: with the therapeutic use of UHF, an electromagnetic (capacitor) field spreading in space acts on the body of a sick animal. The animal, being in the capacitor field, worries, breathing quickens. To use the UHF apparatus, a separate stationary room is required, which completely electrically isolates it for service personnel from the space of the treatment room.

A known method of treating wounds, including a physiotherapeutic effect in the form of exposure to an extremely high frequency electromagnetic field on biologically active points in combination with the use of a 20% aqueous solution of mefopran and a 20% aqueous emulsion of mefopran in castor oil (description of patent RU 2152814 IPC 7 A 61 N 5/02, A 6 N 5/04, A 61 K 31/00).

In the known method of treatment when using a 20% aqueous solution of mefopran and a 20% emulsion of mefopran in castor oil, in conjunction with irradiation of biological points or a wound surface with an electromagnetic extremely high-frequency field, there are disadvantages: an aqueous solution of mefopran and a 20% emulsion are liquid dosage forms that, after application to the wound, partially flow from it, therefore, the effect of the drug is not dosed and short-lived. The high concentration of the active substance mefopran in an aqueous solution and in an emulsion causes a strong irritating effect. An electromagnetic field propagates in space, while there is no direct contact of BAP animals with metal electrodes, therefore, the effect is indirect. In this case, the animal is subjected to additional mental trauma, since the coat is trimmed before manipulation. Particularly aggressive animals, along with painkillers, need to use sedatives and muscle relaxants (prevention of traumatic shock).

The objective of the invention is to increase the effectiveness of the treatment of regenerative wounds in animals and to prevent the development of complications.

The technical result from the use of the invention is to intensify the processes of epithelization of regenerating wounds.

The technical result is achieved by the fact that in the method of treating regenerative wounds in dogs, including daily physiotherapeutic effect on biologically active points (BAP) and application of the drug to the wound surface for 10 days, the physiotherapeutic effect is carried out by alternating pulse current with a frequency of 30 Hz, current magnitude 50 μA, in the mode:

1-3 days - + 28 s / -4 s (time in seconds on the active electrode + / on passive -), with the number of cycles - 2, 32 s * 2 = 64 seconds,

4-5 days - + 4 / -4 s, with the number of cycles - 2, 8 s * 2 = 16 seconds, 6-10 days - -28 s / + 4 s, with the number of cycles - 2, 32 s * 2 = For 64 seconds, the points V2, IG2, V4, IG5, F13, R5, IG17 are chosen as BAT, and Traumeel ointment is used as a medicine and Echinacea compositum solution is additionally used intravenously according to the scheme:

1st day - 1 ml intravenously;

2nd - 2 ml intravenously;

3rd - 2 ml intravenously;

4th - 4 ml intravenously;

5th - 4 ml intravenously;

6th and 7th days - skip;

8th day - 4 ml intravenously;

9th - 2 ml intravenously;

10th - 1 ml intravenously;

and Traumeel solution in / muscle 5 ml 1 time per day.

The influence of alternating electric current on the BAT can be carried out by a multifunctional device for electroreflexotherapy "Luch-1".

The essence of the invention lies in the fact that in the process of treatment using alternative medicine, homeopathic medicines in combination with electroreflexotherapy, their action is aimed at regulating the nervous, endocrine and humoral systems to restore homeostasis. The mechanism of action of these drugs is aimed at detoxifying the body by forming non-toxic compounds, eliminating homotoxins (drainage), restoring cellular and organ metabolism without affecting the pathogenic pathogen, and correlating the immunological reaction. All this stimulates the repair and plastic processes, and also accelerates the process of epithelization of regenerative wounds.

The compositional use of electroreflexotherapy with homeopathic preparations Echinacea compositum and Traumeel increase the activity of cell enzymes, have immunostimulating, strong antiseptic, anti-inflammatory, analgesic and homotoxic properties. All this ensures the qualitative growth of granulation tissue and concentric scarring of the wound, the development of surgical infection is prevented. This creates favorable conditions for reducing the time of rehabilitation of an injured animal. The breakdown products of these drugs do not accumulate in the animal’s body, therefore, do not cause the development of an allergic reaction of an immediate type, and even less so.

The study found that electroacupuncture has a pronounced immunostimulating effect on the animal organism. So, when examining the blood serum of animals on the 2nd day after applying electroacupuncture in the selected mode with homeopathic preparations of Traumeel ointment, Echinacea compositum and Traumeel solutions according to the chosen scheme, a significant increase in the number of T- and B-lymphocytes, factors of nonspecific body protection: lysozyme , compliment and bacterial activity of white blood cells. At the same time, studies in dogs (purulent-enzymatic type of wound cleansing) the entire wound cavity of the orbit of the eye is covered with a small, shiny uniformly granular, pink-red granulation tissue, rather dense consistency. The entire wound surface is covered with a small amount of cloudy grayish-white exudate.

Exposure to alternating pulsed current with a frequency of 30 Hz, current magnitude of 50 μA, during electropuncture reflexotherapy on selected BAT normalizes the immune-energetic functions of the body, ensures the conversion of hyperergic or hypoergic inflammation in the wound zone to normergic, and the growth of full-fledged granulation tissue is activated.

Traumeel ointment and Echinacea compositum and Traumeel solutions stimulate the phagocytic activity of leukocytes and the entire monocytic system as a whole, localize inflammation, prevent septic processes, and eliminate the need to use antiseptic drugs on the wound itself and its surgical treatment.

The drawing schematically shows the BAP of the left-side meridians for exposure to alternating current and their international designation is indicated:

V ₂ - Ching Yu. The meridian of the bladder is located in the middle of the upper edge of the bone orbit. The impact on the BAP is carried out in inflammatory processes in the head, eye diseases, sore throat, and fever.

IG ₂ - Ching Ling. The meridian of the small intestine lies on the border of the middle and inner third of the lower edge of the orbit. The effect on BAT is carried out in a depressed state, an increase in body temperature, trigeminal inflammation, pharyngitis.

V ₄ - Gu-yan. Bladder Meridian. Located at the edge of the third century. BAT is used for lacrimation, neuralgia of the first branch of the trigeminal nerve, rhinitis, laryngitis, allergic reactions.

IG ₅ - Tai Yan. Meridian of the small intestine. It is located in the 10th intercostal space, on the line of the ends of the transcostal processes of the lumbar vertebrae, in the place where the intermuscular complaints are felt, formed by the longest muscle of the back and lumbar-rib muscle. BAT is used for any allergy, pain in the chest and abdomen, lymphadenitis, furunculosis, fever, traumatic edema in the muzzle, intercostal neuralgia, neurodermatitis.

R ₅ - Xue-in. Meridian kidney. Affect BAP in case of cerebrovascular accident, fever, otitis media, fever, as well as aseptic inflammation in the muzzle, hemorrhage, and hematomas.

IG ₁₇ - Point of common action - Chen-ba-dz. Colon Meridian. Strictly median in the upper part of the interdigital gap of the 3-4th finger. BAT is used for chills with fever, depression of immunity, allergies, swelling of the mucous membrane of the throat, lymphadenitis, radioactive skin lesions, general weakness of the body.

An example of the method of treatment

In order to test the possibility of using electroreflexotherapy in veterinary surgery in combination with homeopathic preparations of Traumeel ointment, Echinacea compositum and Traumel solutions conducted experimental clinical studies on dogs. To do this, in the conditions of the Department of Surgery of the All-Ukrainian State Agrarian University on 20 clinically healthy purebred dogs, selected according to the principle of paired analogues, of both sexes, aged 3-6 years old, weighing 20-40 kg, an orbital excentration was performed (removal of the eyeball with over the centuries). On the 3rd day after the operation, after performing surgical treatment of the surgical wound and its circumference, all animals were prescribed electroreflexotherapy with the Luch-1 multifunctional device, by acting on BAT Vs; IGz; V4; IG5; F13; R5; IG ₁₇ , selected as the final and initial parts of the meridians (left or right, since these meridians are symmetrical), which have the highest energy activity. Meridians are selected based on the location of the wound.

The impact was carried out in the following mode:

1-3 days - + 28 s / -4 s (time in seconds on the active electrode + / on passive -), with the number of cycles - 2, 32 s * 2 = 64 seconds,

4-5 days - + 4 / -4 s, with the number of cycles - 2, 8 s * 2 = 16 seconds, 6-10 days - -28 s / + 4 s, with the number of cycles - 2, 32 s * 2 = 64 seconds.

The mechanism of action is aimed at normalizing the immune functions of the body. The treatment is based on equalization of the asymmetry revealed in the diagnosis of electrical conductivity of a localized BAT. For the inhibitory method (for the hyperergic course of inflammation), a current of positive polarity with a short-term automatic change to negative was used; for the exciting method (for the hypoergic course of inflammation), a current of negative polarity with a short-term automatic change to positive was used.

Daily exposure of the Luch-1 multifunctional apparatus for electroreflexotherapy to biologically active points (BAP) V ₂ ; IG ₂ ; V ₄ ; IG5; F13; R ₅ , IG ₁₇ alternating pulsed current with a frequency of 30 Hz, a current strength of 50 μA, current.

In the first phase of the wound healing process, the braking method was used, in which a current of positive polarity was used with a short-term automatic change to negative. The current of positive polarity (on the active electrode + on the passive -) in the treatment mode 28/4 is 32 seconds (s), of which 28 s with a constant current of positive polarity and 4 s of negative polarity, excitability was relied on the basis of current BAT. On the fourth and fifth day, in the second phase of the wound healing process, they were exposed to a current of alternating polarity (+ 4 / -4 s), since the current strength indicators approached the physiological norm, and the interval of the conductivity coefficient in the BAP was higher than 10%. In the following days, until the end of treatment, they used a current of negative polarity (on the active electrode - on the passive +) in the 28/4 treatment regimen. The magnitude of the current strength throughout the course of treatment was 50 μA, the number of treatment cycles -2, for 10 days.

At the same time, animals were treated with homeopathic remedies: Traumeel ointment (Ministry of Health of the Russian Federation No. P 011686 / 02-200), Echinacea compositum solution (reg. No. PVI 2.04.0471-96) and Traumeel solution (reg. No. PVI 2.04.0475-96), mechanism the actions of which are due to the drug information-wave expression of DNA sections that control the body's defenses. Traumeel ointment was placed 1 time per day into the wound cavity. The solution of Echinacea compositum was used intravenously according to the scheme:

1st day - 1 ml intravenously;

2nd - 2 ml intravenously;

3rd - 2 ml intravenously;

4th - 4 ml intravenously;

5th - 4 ml intravenously;

6th and 7th days - skip;

8th day - 4 ml intravenously;

9th - 2 ml intravenously;

10th - 1 ml intravenously;

At the same time, the animals were injected intramuscularly with Traumeel 1 time per day, 5 ml for 10 days.

During the first three days after the application of electropuncture and homeopathic preparations, Traumeel ointment, Echinacea compositum and Traumeel solutions, a qualitative demarcation shaft is formed, which prevents the development of surgical infection in the wound, thereby contributing to the rapid formation of granulation tissue that performs a completely wound defect. Healing ends with concentric scarring.

Complications were absent in all periods of observation.

Complete epithelization of the regenerating tissue occurred on days 14-16.

Claims (2)

1. A method of treating regenerative wounds in dogs, including daily, physiotherapeutic effect on biologically active points (BAP) and applying to the wound surface of the drug for 10 days, characterized in that the physiotherapeutic effect on BAT is carried out by alternating pulse current with a frequency of 30 Hz, by force current 50 μA, in the mode: 1-3 days +28 s / -4 s, with the number of cycles 2; 32 s × 2 is 64 s; 4-5 days +4 s / -4 s, with the number of cycles 2; 8 s × 2 is 16 s, 6-10 days -28 s / + 4 s, with the number of cycles 2; 32 s × 2 is 64 s, where time in seconds on the active electrode + / on the passive-; at the same time, V2, IG2, V4, IG5, F13, R5, IG17 points are selected as BAT, and Traumeel ointment and an additional intravenous solution of Echinacea compositum are used as a medicine according to the scheme: 1st day - 1 ml; 2nd and 3rd days - 2 ml; 4th and 5th days - 4 ml each; 6th and 7th days - skip, 8th day - 4 ml; 9th day - 2 ml, 10th day - 1 ml and intramuscularly the solution "Traumeel" 5 ml once a day. 2. The method according to claim 1, characterized in that the exposure to alternating pulse current is carried out by a multifunctional device for electroreflexotherapy "Ray-1".