RU2203651C2 - Method for treating and preventing gastrointestinal, pulmonary strongylatoses and cystodosis in sheep - Google Patents

Abstract

FIELD: veterinary science, veterinary helminthology. SUBSTANCE: the present innovation deals with treating and preventing monieziasis, tysanieziasis, avitellinosis, dictyocaulosis, nematodiasis, chabertiosis, haemonchosis and other gastrointestinal strongylatoses in sheep. With therapeutic and prophylactic purposes animals are injected with preparation containing polyphen, nilverm and water at the dosage of 0.33 ml/kg body weight both in spring and autumn that provides successfulness on all above- mentioned helminthoses in sheep. The present method provides decreased labor and financial expenses, simplified way of preparation injecting, shortened period of treatment, more stable suspension which could be more easily introduced for animals. EFFECT: higher efficiency and prophylaxis.

Description

 The invention relates to veterinary helminthology and can be used for the treatment and prevention of moniesiosis, tizaniosiosis, avitellinosis, dictiocauliasis, nematodirosis, haberthiosis, hematosis and other gastrointestinal, pulmonary helminthiases of animals.

 There is a method for the treatment and prevention of animal helminthiases by the individual use of polyphene (phenasal) in the form of a powder in doses of 45-100 mg / kg, the effectiveness of which with monieziosis and tisaniasiosis reaches 84-95%, and has no effect on gastrointestinal and other strongylitis ( Kuznetsov M.I., Irgashev I.Kh., Mustakimov A.G., Test of anthelmintics for sheep anoplocephalatosis Veterinary medicine, 1967, 8, pp. 78-79; Demidov N.V., Potemkina V.A. and prevention of animal helminthiasis. - M.: Kolos, 1980, pp. 22-239; Potemkina V.A. chnymi cestodosis animals -. M .: Ear 1973, s.70-74).

 Also known is the method of using nilverm at a dose of 15 mg / kg body weight, twice individually individually for gastrointestinal strongilatoses, the effectiveness of which reaches 92-94.6%, but does not affect intestinal cestodoses (moniesiosis, tizaniesiosis, avitellinosis) (Abduladze K. I., Nikolsky S.N., Kolabsky N.A., Demidov N.A. Parasitology and invasive diseases of agricultural animals .-- M .: Kolos, 1975, 1990; Demidov N.V., Potemkina V.A. Handbook of therapy and prevention of animal helminthiasis. - M .: Kolos, 1980, p.30-31; Golovkina L.P., Panasyuk D.I. Bulletin of the All-Union Institute title of helminthology named after K.I. Scriabin, 1985, p. 40, pp. 24-28).

 The disadvantage of these methods is that anthelmintics must be administered to animals twice, each separately: against some helminths - polyphene, against others - nilverm. Usually animals are invaded with mixed helminthiases (gastrointestinal, pulmonary strongilatoses and cestodoses), in this regard, each treatment requires additional labor and material costs while reducing animal productivity.

 The purpose of the present invention is to increase the efficiency of the method, reduce labor and material costs, facilitate work with the introduction of the drug, reduce the processing time, obtain a stable suspension that is easier to ask animals, expand the arsenal of means to combat helminth infections.

 The suspension made according to our recipe does not lose anthelmintic effectiveness for 4-5 months.

This goal is achieved by the fact that instead of two separately operating chemotherapeutic agents, a suspension of these drugs in combination 1: 3 is introduced. In this case, a new preparative form is formed - polyphenyl. A suspension of the latter is prepared as follows: in 1000.0 g of warm tap water (38-40 ^° C), 45.0 g of nilverm are dissolved and stirred for 5-7 minutes, then 135.0 g of polyphene (phenasal) is added to obtain a stable suspension .

 The proposed suspension of polyphenyl is injected into animals 0.33 ml per 1 kg of live weight. This dose provides high anthelmintic efficacy against gastrointestinal, pulmonary strongilatoses and cestodoses (moniesiosis, tizaniasiosis, dictiocaulosis, nematodirosis, haberthiosis, hematosis, bunostomiasis and other gastrointestinal helminthiases).

 On collective farms, state farms, farms and in the private sector, the incidence of sheep with the above helminthiases reaches 80-100%, depending on the time of year and the location of pastures.

 Experiments to test the proposed method were carried out in 3 farms.

 Example 1. A group of sheep (60 animals) invaded by moniesia, tizaniesia, dictiocauli, nematodiras, habertia, gemonkhusy and other gastrointestinal helminths, was introduced into the suspension of polyphenyl at a dose of 0.33 ml / kg of live weight. The control was a livestock of 30 goals. sheep.

 As a result of the studies, it was found that 100% were released from moniesiosis, tizaniasiosis, avitellinosis, dictiocaulosis, and habertiosis, and with nematodirosis, bunostomiasis, hematosis and other gastrointestinal strongylases, the efficacy was 94.6-98.7%. At the same time, all control sheep remained infested with the above helminths.

 Example 2. In the experimental group, formed from 45 heads of sheep invaded with various helminths (moniesiosis, tizaniosiosis, avitellinosis, dictiocauliasis, nematodirosis, habertiosis, hematosis, bunostomosis and other gastrointestinal helminthiases), a suspension of 0.33 ml of polyphenyl was administered / kg live weight.

 As a result of the studies, it was found that in the experimental group, the effectiveness of a polyphenyl suspension is 100% for moniesiosis, tizaniasiosis, diktiocauliasis, and from 93.4 to 98.6% for nematodirosis, haberthiosis and other gastrointestinal strongilitosis.

 All control sheep (45 animals) remained invasive.

 Example 3. The use of a suspension of polyphenyl at a dose of 0.33 ml / kg of live weight under industrial conditions (568 sheep were treated), also showed its high anthelmintic efficacy against all strongilatoses and cestodoses.

 So, 100 goals were allocated from this flock. sheep for counting efficiency. Of these, 50 goals. was allocated before processing (control) and 50 goals. after administration of a suspension of polyphenyl. They were numbered and conducted research.

 As a result, it was found that when a polyphenyl suspension of 0.33 ml / kg body weight is injected into the body, 100% efficiency is achieved against moniesiosis, tizaniasiosis, dictiocaulosis, haberthiosis, and with bunostomiasis, avitelliosis, nematodirosis, hematosis and other gastrointestinal strongilatoses and cestodose efficacy was 92.0-98.3%.

 All control sheep also remained invasive.

 Accounting and analysis of material, labor costs for the known and proposed methods of treatment and prevention of sheep’s strongilitis and intestinal cestodoses shows that in the new version one treatment is required (in spring and autumn), while according to known methods it is necessary to carry out 2-3 treatments of the livestock in these same terms. In addition, the proposed method does not reduce the productivity of animals associated with stress, violation of the feeding regime and, along with maintaining well-being in animal diseases, contributes to a significant simplification of the work of veterinary specialists, livestock breeders, saving working time and chemotherapy, preventing pasture contamination with eggs and helminth larvae (prevents the infection of animals with helminths).

Claims (1)

A method for the treatment and prevention of gastrointestinal, pulmonary strongilatoses and cestodoses of sheep, characterized in that the animals are injected with the drug at a dose of 0.33 ml / kg body weight, formed by mixing the following components, g:
Nilverm - 45.0
Polyphene - 135.0
Tap water - 1000.0