RU2201206C2 - Agent for treatment of parodontium disease - Google Patents

Abstract

FIELD: medicine, stomatology. SUBSTANCE: agent for treatment of parodontium disease comprises vegetable raw oily extract, eucalyptus aqueous extract, soybean oil, distilled monoglycerides, saturated higher alcohols, cosmetic stearin, 1,2-propylene glycol, nipagin, mint oil, alpha-tocopherol acetate, coniferous provitamin concentrate and purified water. Components are taken in the definite quantitative ratio. Agent retains prolonged contact with parodontium tissues providing positive curative effect, it is not washed out by saliva. EFFECT: improved properties of agent, reduced time of treatment. 1 cl, 2 tbl

Description

 The invention relates to medicine, in particular to medicines in dentistry, and can be used to treat periodontal disease.

 Known substance for the treatment of periodontal disease containing extracts of herbal medicines (A.I. Marchenko, A.I. Baranyuk "Medicinal plants in dentistry" 1881, Chisinau, pp. 25-36).

 The disadvantage of these funds is the low treatment effectiveness associated with the one-sided impact on the disease process, and the high duration of treatment.

 There is a method of treating periodontal disease by prescribing oral baths using extracts of herbal medicines (PI Roshchina, LN Maksimovskaya "Medicines. Dentistry", 1989, Moscow, pp. 75-76).

 A disadvantage of the known methods is the low effectiveness of treatment associated with the rapid loss of activity of drugs due to the constant exposure to saliva, and a significant duration of treatment.

 The purpose of the invention is to increase efficiency and reduce the duration of treatment.

The goal is achieved by the fact that they make a tool containing an aqueous extract of herbal preparations, and its composition includes (%):
Oil extract of medicinal plant materials (1: 10) - 4.00-5.00
Eucalyptus Aqueous Extract (1:10) - 8.00-10.00
Soybean oil - 9.00-10.00
Distilled monoglycerides - 1.00-2.00
Higher fatty alcohols - 1.00-2.00
Cosmetic stearin - 1.15-2.00
1,2-Propylene glycol - 3.50-5.00
Nipagin - 0.20-0.30
Peppermint Oil - 0.20-0.30
Alpha-Tocopherol Acetate - 0.15-0.20
Coniferous provitamin concentrate - 4.00-5.00
Purified water - Up to 100
and for the treatment of periodontal disease, the agent is placed in the affected area, and is separated from the effects of saliva, for example, by placing in an individually made mouthguard.

 The tool is made as follows.

In a 90 ml volume of water extract of eucalyptus (1:10) add 4 ml of an oil extract of a medicinal plant material, 7 ml of soybean oil, 1 ml of monoglycerides, 1.5 ml of higher fatty alcohols, up to 1 ml of cosmetic stearin, 18 ml of 1.2- propylene glycol, 2 ml of nipagin, 0.2 ml of peppermint oil, 0.1 ml of alpha-tocopherol acetate, 4 ml of provitamin coniferous concentrate, mix thoroughly until smooth and placed inside a container with a temperature of 8 ^o C. Before use, in a container with the resulting 870 ml of purified water are added with the substance. The resulting mixture is thoroughly mixed until a homogeneous mass and packaged.

 In the treatment of periodontal disease, the agent is placed in an individually made mouthguard, which is located in the affected area.

 The prevalence of periodontal disease (see tables. 1 and 2).

 Epidemiological studies of schoolchildren in Italy aged 8 to 12 years showed the presence of periodontal lesions in 97% (I. Angelo, G. Cjssard, 1971). According to K. Jacson (1975), Murray J. (1974), in England and the United States under the age of 17 years, gingivitis occurs in 36-90% of cases. B. Kowalski (1974) and A. Semeruk-Mazurkiewier (1974) detected gingivitis in 30.42 and 65% of Polish students, respectively. In the USA, 60% of adolescents suffer from periodontal disease (Green G., 1972). H / Miihiemann and A. Masor, having examined more than 1,000 Zurich schoolchildren aged 7 to 17 years, found inflammatory changes in the gums in 80%.

(1, 5- подвижность зубов; 2, 4 - глубина зубодесневых карманов; 3 - зубы верхней и нижней челюсти).Clinical examples
Patient I., 42 years old (control group):

(1, 5 - tooth mobility; 2, 4 - the depth of the gingival pockets; 3 - teeth of the upper and lower jaw).

 Diagnosis: Chronic generalized periodontitis of moderate severity.

 In the course of treatment, a circular flap operation was performed on the upper and lower jaws with gingivoplasty, and hydroxylapatite and honsurid were introduced into the bone pockets.

 In the postoperative period, the oral cavity was irrigated with chamomile solutions 3 times a day for 10 days, and oral baths with chamomile solutions 3 times a day for 10 days.

Recommended by:
- 2 times a day (in the morning - after breakfast, in the evening - at bedtime), brush your teeth with a toothbrush and toothpaste for 5 minutes;
- repeat oral irrigation with the same solution, as well as conduct oral baths;
- after each meal, rinse your mouth actively for 3 minutes.

1 month after treatment:
- Schiller-Pisarev test - weakly positive;
- hygiene index - 2 points;
- Kulazhenko test - 30 s;
- RMA index - 2 points;
- bleeding index - 0.1.

6 months after treatment:
- Schiller-Pisarev test - weakly positive;
- hygiene index - 3 points;
- Kulazhenko test - 25 s;
- RMA index - 3 points;
- bleeding index - 0.1.

12 months after surgery:
- Schiller-Pisarev test - weakly positive;
- hygiene index - 3 points;
- Kulazhenko test - 22 s;
- RMA index - 3 points;
- bleeding index - 0.1.

(1, 5- подвижность зубов; 2, 4 - глубина зубодесневых карманов; 3 - зубы верхней и нижней челюсти).Patient U., 44 years old (experimental group):

(1, 5 - tooth mobility; 2, 4 - the depth of the gingival pockets; 3 - teeth of the upper and lower jaw).

 Diagnosis: Chronic generalized periodontitis of moderate severity.

 During the treatment, a circular flap operation on the upper and lower jaws with gingivoplasty was performed, as well as hydroxylapatite and honsuride introduced into the bone pockets.

In the postoperative period, an application was carried out containing an aqueous extract of herbal preparations, and its composition included (%):
Oil extract of medicinal plant materials (1: 10) - 4.00-5.00
Eucalyptus Aqueous Extract (1:10) - 8.00-10.00
Soybean oil - 9.00-10.00
Distilled monoglycerides - 1.00-2.00
Higher fatty alcohols - 1.00-2.00
Cosmetic stearin - 1.15-2.00
1,2-Propylene glycol - 3.50-5.00
Nipagin - 0.20-0.30
Peppermint Oil - 0.20-0.30
Alpha-Tocopherol Acetate - 0.15-0.20
Coniferous provitamin concentrate - 4.00-5.00
Purified water - Up to 100
and for the treatment of periodontal disease, the agent was placed in the affected area, and was separated from the effects of saliva by placement in an individually made mouthguard. This manipulation was performed twice within 7 days.

Recommended by:
- 2 times a day (in the morning - after breakfast, in the evening - at bedtime), brush your teeth with a toothbrush and toothpaste for 5 minutes;
- Once a month for 7 days, using an individual mouthguard, repeat applications at home;
- after each meal, rinse your mouth actively for 3 minutes.

1 month after treatment:
- Schiller-Pisarev test is negative;
- hygiene index - 1 point;
- Kulazhenko test - 35 s;
- RMA index - 0 points;
- bleeding index - 0.

6 months after treatment:
- Schiller-Pisarev test is negative;
- hygiene index - 1 point;
- Kulazhenko test - 40 s;
- RMA index - 0 points;
- bleeding index - 0.

12 months after surgery:
- Schiller-Pisarev test is negative;
- hygiene index - 2 points;
- Kulazhenko test - 42 s;
- RMA index - 1 point;
- bleeding index - 0.

 Based on the results of these clinical examples, it follows that it is possible to improve efficiency and reduce treatment time by using the above composition of herbal preparations for application by placing it in an individually made mouthguard.

Claims (1)

An agent for the treatment of periodontal diseases containing an aqueous extract of eucalyptus, characterized in that it additionally contains an oil extract of plant material, soybean oil, distilled monoglycerides, higher fatty alcohols, cosmetic stearin, 1,2-propylene glycol, nipagin, peppermint oil, alpha-tocopherol acetate, provitamin coniferous concentrate in the following components, wt. %:
Oil extract of plant materials (1: 10) - 4.00-5.00
Water extract of eucalyptus (1: 10) - 8.00-10.00
Soybean oil - 9.00-10.00
Distilled monoglycerides - 1.00-2.00
Higher fatty alcohols - 1.00-2.00
Cosmetic stearin - 1.15-2.00
1,2-Propylene glycol - 3.50-5.00
Nipagin - 0.20-0.30
Peppermint Oil - 0.20-0.30
Alpha-Tocopherol Acetate - 0.15-0.20
Coniferous provitamin concentrate - 4.00-5.00
Purified water - Up to 100

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