RU2018134336A3 - - Google Patents

Download PDF

Info

Publication number
RU2018134336A3
RU2018134336A3 RU2018134336A RU2018134336A RU2018134336A3 RU 2018134336 A3 RU2018134336 A3 RU 2018134336A3 RU 2018134336 A RU2018134336 A RU 2018134336A RU 2018134336 A RU2018134336 A RU 2018134336A RU 2018134336 A3 RU2018134336 A3 RU 2018134336A3
Authority
RU
Russia
Application number
RU2018134336A
Other languages
Russian (ru)
Other versions
RU2018134336A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2018134336A publication Critical patent/RU2018134336A/ru
Publication of RU2018134336A3 publication Critical patent/RU2018134336A3/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
RU2018134336A 2016-03-02 2017-02-28 Комбинированная терапия сорафенибом или регорафенибом и фосфорамидатным пролекарством троксацитабина RU2018134336A (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE1650274 2016-03-02
SE1650274-2 2016-03-02
SE1651204 2016-09-08
SE1651204-8 2016-09-08
PCT/SE2017/050186 WO2017151044A1 (en) 2016-03-02 2017-02-28 Combination therapy with sorafenib or regorafenib and a phosphoramidate prodrug of troxacitabine

Publications (2)

Publication Number Publication Date
RU2018134336A RU2018134336A (ru) 2020-04-02
RU2018134336A3 true RU2018134336A3 (enExample) 2020-05-22

Family

ID=59744330

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018134336A RU2018134336A (ru) 2016-03-02 2017-02-28 Комбинированная терапия сорафенибом или регорафенибом и фосфорамидатным пролекарством троксацитабина

Country Status (17)

Country Link
US (2) US10456413B2 (enExample)
EP (1) EP3423061B1 (enExample)
JP (1) JP6968080B2 (enExample)
KR (1) KR102703122B1 (enExample)
CN (2) CN111956646B (enExample)
AU (2) AU2017227516B2 (enExample)
CA (1) CA3014769C (enExample)
ES (1) ES2987989T3 (enExample)
HR (1) HRP20241508T1 (enExample)
HU (1) HUE068940T2 (enExample)
MY (1) MY198140A (enExample)
PL (1) PL3423061T3 (enExample)
RS (1) RS66090B1 (enExample)
RU (1) RU2018134336A (enExample)
SG (1) SG11201806855WA (enExample)
WO (1) WO2017151044A1 (enExample)
ZA (1) ZA201805445B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201806855WA (en) 2016-03-02 2018-09-27 Medivir Ab Combination therapy with sorafenib or regorafenib and a phosphoramidate prodrug of troxacitabine
JP2021512875A (ja) * 2018-02-02 2021-05-20 カースゲン セラピューティクス カンパニー リミテッドCarsgen Therapeutics Co., Ltd. 細胞免疫療法の組み合わせ
JP7337539B2 (ja) 2018-06-21 2023-09-04 メディヴィル・アクチエボラーグ 白血病療法のための塩基修飾シチジンヌクレオチド
HUE065972T2 (hu) * 2019-02-18 2024-06-28 Medivir Ab Gyógyszerkombináció a májrák kezelésére szolgáló eljárásban történõ alkalmazásra
WO2021211039A1 (en) * 2020-04-15 2021-10-21 Medivir Ab Miv-818/lenvatinib combination therapy for liver cancer
KR20210156389A (ko) 2020-06-17 2021-12-27 재단법인대구경북과학기술원 레고라페닙을 유효성분으로 포함하는 염증질환의 예방 또는 치료용 약학적 조성물
IT202000022636A1 (it) 2020-09-25 2022-03-25 Ente Ospedaliero Specializzato In Gastroenterologia Istituto Nazionale Di Ricovero E Cura A Caratter “terapia di combinazione di sorafenib e/o regorafenib con la proteina ricombinante umana proteoglicano-4 per il trattamento dell'epatocarcinoma”
TW202444368A (zh) * 2023-03-30 2024-11-16 瑞典商米迪維艾克提伯拉公司 以氟曲沙他濱布洛帕胺(fostroxacitabine bralpamide)、免疫檢查點抑制劑及vegf拮抗劑治療肝癌之方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2298311B1 (en) 1999-01-13 2012-05-09 Bayer HealthCare LLC w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
CN100376570C (zh) * 2000-10-13 2008-03-26 希拉生物化学股份有限公司 改善胞间传输的二氧戊环类似物
US7235576B1 (en) 2001-01-12 2007-06-26 Bayer Pharmaceuticals Corporation Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
EP1636585B2 (en) 2003-05-20 2012-06-13 Bayer HealthCare LLC Diaryl ureas with kinase inhibiting activity
PL1663978T3 (pl) * 2003-07-23 2008-04-30 Bayer Healthcare Llc Fluoropodstawiony omega-karboksyarylodifenylomocznik do leczenia i profilaktyki chorób i stanów
CA2645633A1 (en) * 2006-04-05 2007-11-01 Novartis Ag Combinations of therapeutic agents for treating cancer
US8728516B2 (en) * 2009-04-30 2014-05-20 Abbvie Inc. Stabilized lipid formulation of apoptosis promoter
CN102190616B (zh) 2010-03-18 2015-07-29 苏州泽璟生物制药有限公司 一种氘代的ω-二苯基脲的合成及生产的方法和工艺
EP2836216B1 (en) 2012-04-13 2022-06-08 Epizyme, Inc. Combination therapy for treating cancer
CN103570613B (zh) 2012-07-18 2016-06-15 苏州泽璟生物制药有限公司 氘代ω-二苯基脲或其盐的多晶型物
EP2879677B1 (en) 2012-07-28 2017-06-14 Calitor Sciences, LLC Substituted pyrazolone compounds and methods of use
US9872919B2 (en) * 2012-09-19 2018-01-23 The Research Foundation For The State University Of New York Prodrugs for selective anticancer therapy
EP3074399A1 (en) * 2013-11-27 2016-10-05 Idenix Pharmaceuticals LLC 2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
JP2017504572A (ja) * 2013-11-27 2017-02-09 アイデニクス・ファーマシューティカルズ・エルエルシー 肝臓癌治療のためのヌクレオチド類
EP3572410B1 (en) * 2014-08-25 2022-07-20 Medivir Aktiebolag Dioxolane analogues of uridine for the treatment of cancer
SG11201806855WA (en) 2016-03-02 2018-09-27 Medivir Ab Combination therapy with sorafenib or regorafenib and a phosphoramidate prodrug of troxacitabine

Also Published As

Publication number Publication date
CA3014769A1 (en) 2017-09-08
EP3423061A4 (en) 2019-11-13
JP2019507764A (ja) 2019-03-22
HUE068940T2 (hu) 2025-02-28
EP3423061C0 (en) 2024-08-07
US20200009166A1 (en) 2020-01-09
PL3423061T3 (pl) 2024-12-16
SG11201806855WA (en) 2018-09-27
US10456413B2 (en) 2019-10-29
BR112018067387A2 (pt) 2019-01-02
US10960017B2 (en) 2021-03-30
CA3014769C (en) 2024-01-09
AU2022203761A1 (en) 2022-06-16
HRP20241508T1 (hr) 2025-01-03
RU2018134336A (ru) 2020-04-02
KR20180118745A (ko) 2018-10-31
KR102703122B1 (ko) 2024-09-04
WO2017151044A1 (en) 2017-09-08
AU2017227516A1 (en) 2018-08-30
AU2017227516B2 (en) 2022-03-03
JP6968080B2 (ja) 2021-11-17
ES2987989T3 (es) 2024-11-18
US20190091246A1 (en) 2019-03-28
CN111956646B (zh) 2023-07-25
EP3423061A1 (en) 2019-01-09
CN109069509B (zh) 2020-10-16
RS66090B1 (sr) 2024-11-29
CN111956646A (zh) 2020-11-20
CN109069509A (zh) 2018-12-21
ZA201805445B (en) 2019-07-31
EP3423061B1 (en) 2024-08-07
AU2022203761B2 (en) 2024-06-13
MY198140A (en) 2023-08-07

Similar Documents

Publication Publication Date Title
BR112018068177A2 (enExample)
BR112019002665A2 (enExample)
BR112018004986A2 (enExample)
BR112019001685A2 (enExample)
BR112019001429A2 (enExample)
BR112019002177A2 (enExample)
BR212018070320U2 (enExample)
BR112018071172A2 (enExample)
BR112019008501B1 (pt) Método realizado por um equipamento de usuário, método realizado por um nó de rede, equipamento de usuário, nó de rede, e, meios de armazenamento legíveis por computador
BR112019003116B1 (pt) Configuração de símbolo de rajada comum de uplink
BR112019001236B1 (pt) Método para executar uma função suplementar para uma consulta de linguagem natural apresentada a um aplicativo de orientação de mídia interativa
BR112019000061B1 (pt) Comutação e modulação de splicing de pré-mrna compreendendo porções de arcabouço bicíclico, com características melhoradas para o tratamento de distúrbios genéticos
BR112018076493B1 (pt) Sistemas e métodos para detecção de posição de feixe de luz
BR112018073794B1 (pt) Partícula, método de geração da partícula, vacina ou composição farmacêutica
BR112018072681B1 (pt) Anticorpos anti-il-1r3 humanizados, fragmento ou derivado do mesmo, seu uso e composição farmacêutica
BR122026002520A2 (pt) Célula, conjunto de vetores para expressar uma proteína de ligação a antígeno biespecífica em uma célula, conjunto de vetores, sistema, método, e, método para produção de uma proteína de ligação a antígeno
BR112019008310A2 (enExample)
BR112019006736A2 (enExample)
BR112019003108A2 (enExample)
BR112018073180B1 (pt) Método para selecionar uma planta de sorgo que exibe maior resistência à antracnose
CN303634147S (zh) 电动三轮车罩壳
CN303613394S (zh) 截止阀
CN303613700S (zh) 蜡烛灯底座(圆形)
CN303559848S (zh) 保温箱(wv)
CN303536431S (zh) 鞋带

Legal Events

Date Code Title Description
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20210329