RU2018113459A3 - - Google Patents

Download PDF

Info

Publication number
RU2018113459A3
RU2018113459A3 RU2018113459A RU2018113459A RU2018113459A3 RU 2018113459 A3 RU2018113459 A3 RU 2018113459A3 RU 2018113459 A RU2018113459 A RU 2018113459A RU 2018113459 A RU2018113459 A RU 2018113459A RU 2018113459 A3 RU2018113459 A3 RU 2018113459A3
Authority
RU
Russia
Application number
RU2018113459A
Other versions
RU2721558C2 (ru
RU2018113459A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/KR2016/010269 external-priority patent/WO2017048018A1/ko
Publication of RU2018113459A3 publication Critical patent/RU2018113459A3/ru
Publication of RU2018113459A publication Critical patent/RU2018113459A/ru
Application granted granted Critical
Publication of RU2721558C2 publication Critical patent/RU2721558C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/541Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6907Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Nanotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
RU2018113459A 2015-09-15 2016-09-12 Фармацевтическая композиция, содержащая анионное лекарственное средство, и способ ее получения RU2721558C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR20150130587 2015-09-15
KR10-2015-0130587 2015-09-15
KR1020160117053A KR101828877B1 (ko) 2015-09-15 2016-09-12 음이온성 약물 함유 약제학적 조성물 및 그 제조방법
PCT/KR2016/010269 WO2017048018A1 (ko) 2015-09-15 2016-09-12 음이온성 약물 함유 약제학적 조성물 및 그 제조방법
KR10-2016-0117053 2016-09-12

Publications (3)

Publication Number Publication Date
RU2018113459A3 true RU2018113459A3 (ru) 2019-10-18
RU2018113459A RU2018113459A (ru) 2019-10-18
RU2721558C2 RU2721558C2 (ru) 2020-05-20

Family

ID=58496160

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018113459A RU2721558C2 (ru) 2015-09-15 2016-09-12 Фармацевтическая композиция, содержащая анионное лекарственное средство, и способ ее получения

Country Status (16)

Country Link
US (2) US11253598B2 (ru)
EP (1) EP3357491B1 (ru)
JP (1) JP6638072B2 (ru)
KR (2) KR101828877B1 (ru)
CN (1) CN108024960B (ru)
AU (1) AU2016324450B2 (ru)
CA (1) CA2998092C (ru)
DK (1) DK3357491T3 (ru)
ES (1) ES2883290T3 (ru)
HK (1) HK1251464A1 (ru)
IL (1) IL257937B (ru)
MX (1) MX2018003096A (ru)
PT (1) PT3357491T (ru)
RU (1) RU2721558C2 (ru)
SG (1) SG11201802073YA (ru)
ZA (1) ZA201802303B (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180344638A1 (en) * 2015-12-18 2018-12-06 Samyang Biopharmaceuticals Corporation Method for preparing polymeric micelle containing anionic drug
KR102175069B1 (ko) * 2017-11-10 2020-11-05 주식회사 삼양바이오팜 음이온성 약물 전달용 지질 나노입자의 동결건조 조성물 및 방법
KR102259513B1 (ko) * 2017-11-16 2021-06-02 주식회사 삼양홀딩스 음이온성 약물 함유 약제학적 조성물의 동결건조 조성물 및 방법
KR20190127277A (ko) * 2018-05-04 2019-11-13 주식회사 삼양바이오팜 mRNA 전달용 고분자 나노입자 조성물 및 그 제조방법
AU2019317180B2 (en) * 2018-08-07 2022-08-11 Samyang Holdings Corporation Polymer nanoparticle composition for delivering virus, and preparation method therefor
CN109136271B (zh) * 2018-09-20 2021-07-20 西北工业大学 阳离子聚乙烯胺线形高分子作为转基因载体的应用
JP2023500921A (ja) 2019-11-07 2023-01-11 サムヤン ホールディングス コーポレイション 免疫誘導用ポリマーナノ粒子組成物及びその製造方法
EP4062908A4 (en) * 2019-11-22 2024-01-24 Samyang Holdings Corporation KIT FOR PREPARING A NANOPARTICLE COMPOSITION FOR DRUG DELIVERY
AU2020407348A1 (en) * 2019-12-20 2022-07-14 Samyang Holdings Corporation Kit for preparing nanoparticle composition for drug delivery, comprising polylactic acid salt
BR112022020991A2 (pt) * 2020-08-31 2023-03-07 Vaim Co Ltd Dispersão de polímero biodegradável, composição compreendendo a mesma e sistema de melhoria da pele
CN117241791A (zh) * 2021-04-30 2023-12-15 三养控股公司 包含不含两亲聚合物的纳米颗粒的用于药物递送的组合物
GB202108444D0 (en) * 2021-06-14 2021-07-28 Imperial College Innovations Ltd Sub-micron particle
CN114569577B (zh) * 2022-03-07 2023-04-11 晟迪生物医药(苏州)有限公司 一种聚合物包衣纳米粒及其制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0180334B1 (ko) 1995-09-21 1999-03-20 김윤 블럭 공중합체 미셀을 이용한 약물전달체 및 이에 약물을 봉입하는 방법
US6458382B1 (en) 1999-11-12 2002-10-01 Mirus Corporation Nucleic acid transfer complexes
ATE450621T2 (de) 2000-03-30 2009-12-15 Whitehead Biomedical Inst Mediatoren von rns-interferenz, die rns- sequenzspezifisch sind
CA2472170A1 (en) 2001-12-28 2003-07-24 Supratek Pharma Inc. Pharmaceutical compositions comprising polyanionic polymers and amphiphilic block copolymers and methods of use thereof to improve gene expression
AU2003288902A1 (en) * 2002-09-06 2004-04-08 Genteric, Inc. Microcapsules and methods of use
WO2005107813A1 (en) 2004-05-06 2005-11-17 Samyang Corporation Delivery system for bioactive agents on the basis of a polymeric drug carrier comprising an amphiphilic block polymer and a polylacticacid derivative
KR100949791B1 (ko) 2007-12-18 2010-03-30 이동기 오프-타겟 효과를 최소화하고 RNAi 기구를 포화시키지않는 신규한 siRNA 구조 및 그 용도
US20090312402A1 (en) * 2008-05-20 2009-12-17 Contag Christopher H Encapsulated nanoparticles for drug delivery
CA2732412C (en) * 2008-07-30 2014-12-09 Lei Yu Retinoid-targeted drug carriers
EP2376062B1 (en) 2008-12-26 2017-04-26 Samyang Biopharmaceuticals Corporation Preparation method of polymeric micellar nanoparticles composition containing a poorly water-soluble drug
US20110268772A1 (en) * 2008-12-26 2011-11-03 Samyang Corporation Pharmaceutical composition containing an anionic drug and a production method thereof
KR101296326B1 (ko) * 2009-12-30 2013-08-14 주식회사 삼양바이오팜 폴리락트산을 포함하는 음이온성 약물 전달용 조성물 및 그 제조 방법
US9314529B2 (en) 2010-07-09 2016-04-19 The University Of Tokyo Nucleic acid delivery composition and carrier composition, pharmaceutical composition using the same, and method for nucleic acid delivery
EP2658577A4 (en) 2010-12-30 2016-08-24 Samyang Biopharmaceuticals CARRIER FOR NEGATIVELY LOADED MEDICAMENTS WITH A CATIONIC LIPID AND METHOD FOR THE PRODUCTION THEREOF
KR101480055B1 (ko) * 2012-04-04 2015-01-09 주식회사 삼양바이오팜 음이온성 약물 전달체의 제조 방법
KR102109188B1 (ko) * 2013-04-01 2020-05-11 삼성전자주식회사 양이온성 지질을 포함하는 온도민감성 리포좀 및 그의 용도
WO2014169007A2 (en) 2013-04-09 2014-10-16 University Of Georgia Research Foundation Inc. Combination therapeutic nanoparticles

Also Published As

Publication number Publication date
DK3357491T3 (da) 2021-08-02
IL257937B (en) 2020-10-29
MX2018003096A (es) 2018-05-11
PT3357491T (pt) 2021-08-02
CA2998092A1 (en) 2017-03-23
EP3357491B1 (en) 2021-06-02
SG11201802073YA (en) 2018-04-27
JP6638072B2 (ja) 2020-01-29
CN108024960A (zh) 2018-05-11
RU2721558C2 (ru) 2020-05-20
ES2883290T3 (es) 2021-12-07
KR20180008854A (ko) 2018-01-24
JP2018527413A (ja) 2018-09-20
US20220125929A1 (en) 2022-04-28
EP3357491A1 (en) 2018-08-08
HK1251464A1 (zh) 2019-02-01
KR101828877B1 (ko) 2018-02-14
RU2018113459A (ru) 2019-10-18
CN108024960B (zh) 2020-12-29
KR20170032858A (ko) 2017-03-23
CA2998092C (en) 2020-08-04
KR101948839B1 (ko) 2019-02-15
AU2016324450B2 (en) 2019-04-18
AU2016324450A1 (en) 2018-04-12
IL257937A (en) 2018-05-31
US11253598B2 (en) 2022-02-22
US20180250409A1 (en) 2018-09-06
EP3357491A4 (en) 2019-05-08
ZA201802303B (en) 2019-01-30

Similar Documents

Publication Publication Date Title
RU2018113459A3 (ru)
BR112018002834A2 (ru)
BR112018002644A2 (ru)
BR202016025784U2 (ru)
BE2015C047I2 (ru)
BE2015C044I2 (ru)
CN303066491S (ru)
BR0007834B1 (ru)
CN303068058S (ru)
CN303067274S (ru)
CN303066882S (ru)
BR0008158B1 (ru)
BR9915375B1 (ru)
CN303068831S (ru)
BR0000126B1 (ru)
CN303071478S (ru)
BR0207602B1 (ru)
BR0010150B1 (ru)
BR0009994B1 (ru)
BR0009942B1 (ru)
BR0009761B1 (ru)
BR0009757B1 (ru)
BR0009717B1 (ru)
CN303072311S (ru)
BR0009649B1 (ru)

Legal Events

Date Code Title Description
PC43 Official registration of the transfer of the exclusive right without contract for inventions

Effective date: 20210811