RU2018107941A3 - - Google Patents

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Publication number
RU2018107941A3
RU2018107941A3 RU2018107941A RU2018107941A RU2018107941A3 RU 2018107941 A3 RU2018107941 A3 RU 2018107941A3 RU 2018107941 A RU2018107941 A RU 2018107941A RU 2018107941 A RU2018107941 A RU 2018107941A RU 2018107941 A3 RU2018107941 A3 RU 2018107941A3
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RU
Russia
Application number
RU2018107941A
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RU2736501C2 (ru
RU2018107941A (ru
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Publication of RU2018107941A publication Critical patent/RU2018107941A/ru
Publication of RU2018107941A3 publication Critical patent/RU2018107941A3/ru
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Publication of RU2736501C2 publication Critical patent/RU2736501C2/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2018107941A 2015-08-07 2016-08-05 Трициклические соединения и их применение для лечения рака RU2736501C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1514018.9A GB201514018D0 (en) 2015-08-07 2015-08-07 Novel tricyclic compounds and their use in the treatment of cancer
GB1514018.9 2015-08-07
PCT/US2016/045730 WO2017027358A1 (en) 2015-08-07 2016-08-05 Tricyclic compounds and their use in the treatment of cancer

Publications (3)

Publication Number Publication Date
RU2018107941A RU2018107941A (ru) 2019-09-09
RU2018107941A3 true RU2018107941A3 (ru) 2019-09-09
RU2736501C2 RU2736501C2 (ru) 2020-11-17

Family

ID=54200421

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018107941A RU2736501C2 (ru) 2015-08-07 2016-08-05 Трициклические соединения и их применение для лечения рака

Country Status (12)

Country Link
US (1) US10881653B2 (ru)
EP (1) EP3331883A1 (ru)
JP (1) JP6545908B2 (ru)
KR (2) KR20180032647A (ru)
CN (1) CN108026096A (ru)
AU (1) AU2016307438B2 (ru)
CA (1) CA2995075C (ru)
GB (1) GB201514018D0 (ru)
MA (1) MA42914A (ru)
MX (1) MX2018001575A (ru)
RU (1) RU2736501C2 (ru)
WO (1) WO2017027358A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210038577A1 (en) * 2018-02-12 2021-02-11 Cinda Pharma Ab Thioredoxin reductase inhibitors for use in the treatment of cancer
JP7337174B2 (ja) 2018-09-18 2023-09-01 ニカング セラピューティクス, インコーポレイテッド Srcホモロジー-2ホスファターゼ阻害剤としての三置換ヘテロアリール誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7550458B2 (en) * 2005-10-18 2009-06-23 Bristol-Myers Squibb Company Tricycloundecane compounds useful as modulators of nuclear hormone receptor function
EP2062181A2 (en) 2006-08-28 2009-05-27 Dan Theodorescu Prediction of an agent's or agents' activity across different cells and tissue types
PL219045B1 (pl) * 2010-10-16 2015-03-31 Inst Chemii Organicznej Polskiej Akademii Nauk Nowe estry (acyloksymetylo)akrylamidu, kompozycja farmaceutyczna zawierająca je oraz ich zastosowanie

Also Published As

Publication number Publication date
RU2736501C2 (ru) 2020-11-17
RU2018107941A (ru) 2019-09-09
WO2017027358A1 (en) 2017-02-16
KR20200102529A (ko) 2020-08-31
EP3331883A1 (en) 2018-06-13
US10881653B2 (en) 2021-01-05
KR102428549B1 (ko) 2022-08-03
AU2016307438B2 (en) 2019-07-11
AU2016307438A1 (en) 2018-02-22
US20200113889A1 (en) 2020-04-16
MX2018001575A (es) 2018-11-09
KR20180032647A (ko) 2018-03-30
GB201514018D0 (en) 2015-09-23
MA42914A (fr) 2018-08-01
CA2995075A1 (en) 2017-02-16
JP2018522948A (ja) 2018-08-16
WO2017027358A8 (en) 2017-05-11
CN108026096A (zh) 2018-05-11
CA2995075C (en) 2022-05-31
JP6545908B2 (ja) 2019-07-17

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