RU2017127024A3 - - Google Patents

Download PDF

Info

Publication number
RU2017127024A3
RU2017127024A3 RU2017127024A RU2017127024A RU2017127024A3 RU 2017127024 A3 RU2017127024 A3 RU 2017127024A3 RU 2017127024 A RU2017127024 A RU 2017127024A RU 2017127024 A RU2017127024 A RU 2017127024A RU 2017127024 A3 RU2017127024 A3 RU 2017127024A3
Authority
RU
Russia
Application number
RU2017127024A
Other versions
RU2732120C2 (ru
RU2017127024A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2017127024A publication Critical patent/RU2017127024A/ru
Publication of RU2017127024A3 publication Critical patent/RU2017127024A3/ru
Application granted granted Critical
Publication of RU2732120C2 publication Critical patent/RU2732120C2/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • C12N15/869Herpesviral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16632Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RU2017127024A 2015-02-11 2016-02-11 Герпесвирус с измененным спектром мишеней, содержащий гибридный гликопротеин н RU2732120C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15425012.0 2015-02-11
EP15425012 2015-02-11
PCT/EP2016/052879 WO2016128497A1 (en) 2015-02-11 2016-02-11 Retargeted herpesvirus with a glycoprotein h fusion

Publications (3)

Publication Number Publication Date
RU2017127024A RU2017127024A (ru) 2019-03-12
RU2017127024A3 true RU2017127024A3 (ru) 2019-09-03
RU2732120C2 RU2732120C2 (ru) 2020-09-11

Family

ID=52814952

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017127024A RU2732120C2 (ru) 2015-02-11 2016-02-11 Герпесвирус с измененным спектром мишеней, содержащий гибридный гликопротеин н

Country Status (13)

Country Link
US (1) US10421979B2 (ru)
EP (1) EP3256570B1 (ru)
JP (1) JP6751721B2 (ru)
CN (1) CN107406834B (ru)
AU (1) AU2016217906B2 (ru)
CA (1) CA2974868A1 (ru)
DK (1) DK3256570T3 (ru)
ES (1) ES2874584T3 (ru)
HU (1) HUE054563T2 (ru)
PL (1) PL3256570T3 (ru)
PT (1) PT3256570T (ru)
RU (1) RU2732120C2 (ru)
WO (1) WO2016128497A1 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3235908A1 (en) * 2016-04-21 2017-10-25 Ecole Normale Superieure De Lyon Methods for selectively modulating the activity of distinct subtypes of cells
CN109563490A (zh) 2016-06-09 2019-04-02 大学之母博洛尼亚大学 具有经修饰的糖蛋白b的疱疹病毒
AU2017276726B2 (en) 2016-06-09 2023-09-21 Alma Mater Studiorum Universita Di Bologna Herpesvirus with modified glycoprotein D
CN111918660A (zh) * 2018-01-24 2020-11-10 复诺健生物科技加拿大有限公司 重组病毒疫苗
CN108913665B (zh) * 2018-07-26 2021-06-22 江苏省农业科学院 一种分泌抗CpHV-1单克隆抗体的杂交瘤细胞株及其应用
KR20210023751A (ko) * 2019-08-22 2021-03-04 주식회사 젠셀메드 암세포 표적화 영역과 hvem의 세포외 도메인의 융합 단백질을 발현할 수 있는 발현 카세트를 가지는 재조합 헤르페스 심플렉스 바이러스 및 그 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0714578D0 (en) * 2007-07-26 2007-09-05 Crusade Lab Ltd Viruses
RU2010111725A (ru) * 2007-08-28 2011-10-10 Юниверсите Де Льеж (Be) Рекомбинантный герпесвирус кои (khv) или герпесвирус 3 семейства карповых (cyhv-3) и вакцина для профилактики заболевания, вызванного khv/cyhv-3 у cyprinus carpio или cyprinus carpio koi
PT2293804E (pt) * 2008-05-29 2013-08-29 Univ Bologna Alma Mater Vírus herpes simplex (hsv) com tropismo modificado, suas utilizações e processo de preparação
US9089537B2 (en) * 2010-02-26 2015-07-28 The Trustees Of The University Of Pennslyvania Subunit vaccines for herpes viruses and methods of use
MX2016005488A (es) * 2013-10-28 2016-10-03 Univ Of Pittsburgh - Of The Commonwealth System Of Higher Education Vector hsv oncolitico.

Also Published As

Publication number Publication date
AU2016217906B2 (en) 2021-09-02
EP3256570A1 (en) 2017-12-20
CN107406834B (zh) 2021-03-16
ES2874584T3 (es) 2021-11-05
AU2016217906A1 (en) 2017-08-10
EP3256570B1 (en) 2021-03-31
PT3256570T (pt) 2021-06-18
JP2018512115A (ja) 2018-05-17
US10421979B2 (en) 2019-09-24
CA2974868A1 (en) 2016-08-18
US20180002723A1 (en) 2018-01-04
HUE054563T2 (hu) 2021-09-28
WO2016128497A1 (en) 2016-08-18
DK3256570T3 (da) 2021-06-14
JP6751721B2 (ja) 2020-09-09
RU2732120C2 (ru) 2020-09-11
PL3256570T3 (pl) 2021-11-29
CN107406834A (zh) 2017-11-28
RU2017127024A (ru) 2019-03-12

Similar Documents

Publication Publication Date Title
RU2017127024A3 (ru)
BE2015C044I2 (ru)
BR0003166B1 (ru)
BR0002802B1 (ru)
CN303107628S (ru)
CN303103407S (ru)
CN303090026S (ru)
CN303080691S (ru)
CN303069476S (ru)
CN303067941S (ru)
BR0317682B1 (ru)
BR0313189B1 (ru)
BR0002874B1 (ru)
BR0107790B1 (ru)
BR0010150B1 (ru)
BR0009994B1 (ru)
BR0009942B1 (ru)
BR0009761B1 (ru)
BR0009757B1 (ru)
BR0009717B1 (ru)
BR0009649B1 (ru)
BR0009373B1 (ru)
BR0009349B1 (ru)
BR0009182B1 (ru)
BR0008874B1 (ru)