RU2017123388A - Пептиды и их применение в уходе за кожей - Google Patents

Пептиды и их применение в уходе за кожей Download PDF

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Publication number
RU2017123388A
RU2017123388A RU2017123388A RU2017123388A RU2017123388A RU 2017123388 A RU2017123388 A RU 2017123388A RU 2017123388 A RU2017123388 A RU 2017123388A RU 2017123388 A RU2017123388 A RU 2017123388A RU 2017123388 A RU2017123388 A RU 2017123388A
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RU
Russia
Prior art keywords
specified
peptide
composition
amino acids
skin
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RU2017123388A
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English (en)
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RU2709778C2 (ru
RU2017123388A3 (ru
Inventor
БОЛДИС Джоланта ИДКОВИАК
Ума САНТАНАМ
Original Assignee
Эйвон Продактс, Инк.
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Publication of RU2017123388A publication Critical patent/RU2017123388A/ru
Publication of RU2017123388A3 publication Critical patent/RU2017123388A3/ru
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof

Claims (15)

1. Способ уменьшения появления дерматологических признаков старения, включающий в себя наружное нанесение на кожу композиции, содержащей, в пригодном для наружного применения средстве доставки, пептид, имеющий в своем составе от 3 до 12 аминокислот, соответствующих последовательности GDF11, или его соль, сложный эфир или пролекарство.
2. Способ согласно п. 1, где указанные дерматологические признаки старения включают появление мелких морщинок и морщин.
3. Способ согласно п. 1, где указанный пептид повышает выработку коллагена в коже.
4. Способ согласно п. 1, где указанный пептид повышает выработку гиалуроновой кислоты в коже.
5. Способ согласно п. 1, где указанную композицию наносят не менее одного раза в день в течение не менее одной недели.
6. Способ согласно п. 1, где указанный пептид имеет в своем составе от 3 до 8 аминокислот, соответствующих последовательности GDF11.
7. Способ согласно п. 1, где указанный пептид имеет в своем составе от 3 до 6 аминокислот, соответствующих последовательности GDF11.
8. Способ согласно п. 1, где указанный пептид имеет в своем составе MVV(SEQ ID NO: 7).
9. Способ согласно п. 1, где указанный пептид состоит в основном из MVV(SEQ ID NO: 7).
10. Способ согласно п. 1, где указанный пептид имеет в своем составе три или четыре последовательные аминокислоты из аминокислот 395-407 в GDF11.
11. Способ согласно п. 1, где указанный пептид дополнительно содержит углеводородную цепь на аминном конце.
12. Способ согласно п. 11, где указанная углеводородная цепь представляет собой C1-24 алифатический углеводород.
13. Способ согласно п. 1, где указанная композиция включает в себя пролекарство указанного пептида, где указанное пролекарство включает N-ацетильные производные указанного пептида.
14. Способ уменьшения появления дерматологических признаков старения, включающий в себя наружное нанесение на кожу композиции, содержащей, в пригодном для наружного применения средстве доставки, пептид, имеющий в своем составе от 3 до 12 аминокислот, соответствующих последовательности TGFβ, или его соль, сложный эфир или пролекарство.
15. Способ согласно п. 14, где указанные дерматологические признаки старения включают появление мелких морщинок и морщин.
RU2017123388A 2014-12-23 2015-09-03 Пептиды и их применение в уходе за кожей RU2709778C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462095873P 2014-12-23 2014-12-23
US62/095,873 2014-12-23
PCT/US2015/048240 WO2016105607A1 (en) 2014-12-23 2015-09-03 Peptides and their use in the treatment of skin

Publications (3)

Publication Number Publication Date
RU2017123388A true RU2017123388A (ru) 2019-01-24
RU2017123388A3 RU2017123388A3 (ru) 2019-01-25
RU2709778C2 RU2709778C2 (ru) 2019-12-20

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RU2017123388A RU2709778C2 (ru) 2014-12-23 2015-09-03 Пептиды и их применение в уходе за кожей

Country Status (10)

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US (1) US10034826B2 (ru)
EP (1) EP3236992A4 (ru)
CN (1) CN107106652A (ru)
BR (1) BR112017013696B1 (ru)
CA (1) CA2972015A1 (ru)
MX (1) MX2017008454A (ru)
PH (1) PH12017501070A1 (ru)
RU (1) RU2709778C2 (ru)
WO (1) WO2016105607A1 (ru)
ZA (1) ZA201704726B (ru)

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US11766467B2 (en) 2017-09-01 2023-09-26 University Of Wyoming Methods of treating wounds using cathepsin K inhibitors
US10758559B1 (en) 2017-09-01 2020-09-01 University Of Wyoming Targeting cathepsin K to facilitate wound healing
CN117777238A (zh) * 2017-09-15 2024-03-29 凯恩塞恩斯株式会社 作为自身免疫疾病及骨病治疗剂的肽的用途
CN108586575B (zh) * 2018-04-11 2020-08-14 福建省中科生物股份有限公司 一种多肽及其皮肤修复功能的应用
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Publication number Publication date
US10034826B2 (en) 2018-07-31
RU2709778C2 (ru) 2019-12-20
PH12017501070A1 (en) 2017-12-11
CA2972015A1 (en) 2016-06-30
EP3236992A4 (en) 2018-09-05
EP3236992A1 (en) 2017-11-01
MX2017008454A (es) 2017-10-31
BR112017013696B1 (pt) 2024-01-02
RU2017123388A3 (ru) 2019-01-25
CN107106652A (zh) 2017-08-29
BR112017013696A2 (pt) 2018-02-06
WO2016105607A1 (en) 2016-06-30
ZA201704726B (en) 2019-01-30
US20160175225A1 (en) 2016-06-23

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