RU2017120846A3 - - Google Patents

Download PDF

Info

Publication number
RU2017120846A3
RU2017120846A3 RU2017120846A RU2017120846A RU2017120846A3 RU 2017120846 A3 RU2017120846 A3 RU 2017120846A3 RU 2017120846 A RU2017120846 A RU 2017120846A RU 2017120846 A RU2017120846 A RU 2017120846A RU 2017120846 A3 RU2017120846 A3 RU 2017120846A3
Authority
RU
Russia
Application number
RU2017120846A
Other languages
Russian (ru)
Other versions
RU2017120846A (ru
RU2723990C3 (ru
RU2723990C2 (ru
RU2723990C9 (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54848892&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2017120846(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of RU2017120846A publication Critical patent/RU2017120846A/ru
Publication of RU2017120846A3 publication Critical patent/RU2017120846A3/ru
Publication of RU2723990C2 publication Critical patent/RU2723990C2/ru
Application granted granted Critical
Publication of RU2723990C9 publication Critical patent/RU2723990C9/ru
Publication of RU2723990C3 publication Critical patent/RU2723990C3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/10—Protein-tyrosine kinases (2.7.10)
    • C12Y207/10001—Receptor protein-tyrosine kinase (2.7.10.1)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RU2017120846A 2015-11-16 Кристаллическая форма (s)-n-(5-((r)-2-(2,5-дифторфенил)-пирролидин-1-ил)-пиразоло[1,5-a]пиримидин-3-ил)-3-гидроксипирролидин-1-карбоксамида гидросульфата RU2723990C3 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462080374P 2014-11-16 2014-11-16
US62/080,374 2014-11-16
US201562169545P 2015-06-01 2015-06-01
US62/169,545 2015-06-01
PCT/US2015/060953 WO2016077841A1 (en) 2014-11-16 2015-11-16 Crystalline form of (s)-n-(5-((r)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate

Publications (5)

Publication Number Publication Date
RU2017120846A RU2017120846A (ru) 2018-12-18
RU2017120846A3 true RU2017120846A3 (enExample) 2019-05-08
RU2723990C2 RU2723990C2 (ru) 2020-06-18
RU2723990C9 RU2723990C9 (ru) 2023-01-10
RU2723990C3 RU2723990C3 (ru) 2024-03-18

Family

ID=

Also Published As

Publication number Publication date
RU2017120846A (ru) 2018-12-18
US20180207162A1 (en) 2018-07-26
JP2021169496A (ja) 2021-10-28
CR20170263A (es) 2017-10-18
EP3218380B1 (en) 2021-03-17
EP3218380A1 (en) 2017-09-20
CN113354649A (zh) 2021-09-07
WO2016077841A1 (en) 2016-05-19
US9782414B2 (en) 2017-10-10
SG11201703962XA (en) 2017-06-29
CL2017001249A1 (es) 2017-12-15
ZA201703501B (en) 2021-09-29
JP6914834B2 (ja) 2021-08-04
BR112017010141A2 (pt) 2018-03-06
US10799505B2 (en) 2020-10-13
HRP20230271T1 (hr) 2023-06-09
PH12021550809A1 (en) 2022-02-14
IL290905B2 (en) 2023-09-01
CO2017005483A2 (es) 2017-11-30
ES2941630T3 (es) 2023-05-24
US20180021342A1 (en) 2018-01-25
CA2967951A1 (en) 2016-05-19
TW202206436A (zh) 2022-02-16
JP2017535550A (ja) 2017-11-30
IL290905B1 (en) 2023-05-01
IL252270B (en) 2022-04-01
RU2723990C2 (ru) 2020-06-18
CN113354649B (zh) 2024-12-10
US20170165267A1 (en) 2017-06-15
SI3699181T1 (sl) 2023-06-30
LT3699181T (lt) 2023-05-10
KR102649887B1 (ko) 2024-03-22
MX2017006412A (es) 2017-09-12
HK1244483A1 (zh) 2018-08-10
PT3699181T (pt) 2023-04-05
CY1125935T1 (el) 2026-02-25
HUE061448T2 (hu) 2023-07-28
KR20170082628A (ko) 2017-07-14
IL290905A (en) 2022-04-01
RS64122B1 (sr) 2023-05-31
AU2015346046B2 (en) 2020-06-25
TW201625636A (zh) 2016-07-16
US10813936B2 (en) 2020-10-27
CN107428760B (zh) 2021-04-27
AU2015346046A1 (en) 2017-06-08
TWI767858B (zh) 2022-06-11
MX2020011079A (es) 2020-11-09
US20200000807A1 (en) 2020-01-02
US10172861B2 (en) 2019-01-08
US10285993B2 (en) 2019-05-14
CN107428760A (zh) 2017-12-01
CA2967951C (en) 2023-11-07
EP3699181A1 (en) 2020-08-26
PL3699181T3 (pl) 2023-05-22
PH12017500900A1 (en) 2017-12-04
MX376478B (es) 2025-03-07
EP3699181B1 (en) 2023-03-01
FI3699181T3 (fi) 2023-03-28
DK3699181T3 (da) 2023-03-20
NZ731909A (en) 2023-11-24
UA123044C2 (uk) 2021-02-10
IL252270A0 (en) 2017-07-31
US20160137654A1 (en) 2016-05-19
TWI746426B (zh) 2021-11-21

Similar Documents

Publication Publication Date Title
BR112016016552A2 (enExample)
BR112016015519A2 (enExample)
BR112016015890A2 (enExample)
BR112016016490A2 (enExample)
BR112016016612A2 (enExample)
BR112016016421A2 (enExample)
BR112016016417A2 (enExample)
BR112016016106A2 (enExample)
BR112016012568A2 (enExample)
BR112016016558A2 (enExample)
BR112016011585A2 (enExample)
BR112016015915A2 (enExample)
BR112016025808A2 (enExample)
BR112016016468A2 (enExample)
BR112016000228A2 (enExample)
BR112016012283A2 (enExample)
BR112016026316A2 (enExample)
BR112016016459A2 (enExample)
BR112016016028A2 (enExample)
BR112016003522A2 (enExample)
BR112016016111A2 (enExample)
BR112016014482A2 (enExample)
BR112016015054A2 (enExample)
AP2017009684A0 (enExample)
BR112016015896A2 (enExample)

Legal Events

Date Code Title Description
HE9A Changing address for correspondence with an applicant