RU2016146938A - Композиции, содержащие полимерную серу, и способы их применения - Google Patents
Композиции, содержащие полимерную серу, и способы их применения Download PDFInfo
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- RU2016146938A RU2016146938A RU2016146938A RU2016146938A RU2016146938A RU 2016146938 A RU2016146938 A RU 2016146938A RU 2016146938 A RU2016146938 A RU 2016146938A RU 2016146938 A RU2016146938 A RU 2016146938A RU 2016146938 A RU2016146938 A RU 2016146938A
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- Prior art keywords
- composition
- cysteine
- skin
- personal care
- sulfur
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims 18
- 238000000034 method Methods 0.000 title claims 12
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 title claims 11
- 229910052717 sulfur Inorganic materials 0.000 title claims 11
- 239000011593 sulfur Substances 0.000 title claims 11
- 229920000642 polymer Polymers 0.000 title claims 7
- 230000007170 pathology Effects 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 5
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 claims 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims 4
- PWKSKIMOESPYIA-UHFFFAOYSA-N 2-acetamido-3-sulfanylpropanoic acid Chemical compound CC(=O)NC(CS)C(O)=O PWKSKIMOESPYIA-UHFFFAOYSA-N 0.000 claims 3
- 208000002874 Acne Vulgaris Diseases 0.000 claims 3
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 claims 3
- 206010000496 acne Diseases 0.000 claims 3
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 3
- 229960002433 cysteine Drugs 0.000 claims 3
- 235000018417 cysteine Nutrition 0.000 claims 3
- 150000003573 thiols Chemical class 0.000 claims 3
- 230000000699 topical effect Effects 0.000 claims 3
- 239000004342 Benzoyl peroxide Substances 0.000 claims 2
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 claims 2
- 201000004624 Dermatitis Diseases 0.000 claims 2
- 229940024606 amino acid Drugs 0.000 claims 2
- 235000001014 amino acid Nutrition 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 235000019400 benzoyl peroxide Nutrition 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 2
- 229960004889 salicylic acid Drugs 0.000 claims 2
- 230000009759 skin aging Effects 0.000 claims 2
- 230000008591 skin barrier function Effects 0.000 claims 2
- QIJRTFXNRTXDIP-UHFFFAOYSA-N (1-carboxy-2-sulfanylethyl)azanium;chloride;hydrate Chemical compound O.Cl.SCC(N)C(O)=O QIJRTFXNRTXDIP-UHFFFAOYSA-N 0.000 claims 1
- KCYSKCOUMWIVKR-VKHMYHEASA-N (2R)-2-(hydrazinylmethylideneamino)-3-sulfanylpropanoic acid Chemical compound NN=CN[C@@H](CS)C(=O)O KCYSKCOUMWIVKR-VKHMYHEASA-N 0.000 claims 1
- XWRZKLKALVJDDS-REOHCLBHSA-N (2r)-2-(diaminomethylideneamino)-3-sulfanylpropanoic acid Chemical compound NC(N)=N[C@@H](CS)C(O)=O XWRZKLKALVJDDS-REOHCLBHSA-N 0.000 claims 1
- JJVXHDTWVIPRBZ-VKHMYHEASA-N (2r)-2-[carboxy(methyl)amino]-3-sulfanylpropanoic acid Chemical compound OC(=O)N(C)[C@@H](CS)C(O)=O JJVXHDTWVIPRBZ-VKHMYHEASA-N 0.000 claims 1
- VYPKEODFNOEZGS-VIFPVBQESA-N (2r)-2-acetamido-3-(2-hydroxybenzoyl)sulfanylpropanoic acid Chemical compound CC(=O)N[C@H](C(O)=O)CSC(=O)C1=CC=CC=C1O VYPKEODFNOEZGS-VIFPVBQESA-N 0.000 claims 1
- BMLMGCPTLHPWPY-REOHCLBHSA-N (4R)-2-oxo-4-thiazolidinecarboxylic acid Chemical compound OC(=O)[C@@H]1CSC(=O)N1 BMLMGCPTLHPWPY-REOHCLBHSA-N 0.000 claims 1
- 206010063409 Acarodermatitis Diseases 0.000 claims 1
- XTURYZYJYQRJDO-BNAHBJSTSA-N Acetyl-farnesyl-cysteine Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CSC[C@@H](C(O)=O)NC(C)=O XTURYZYJYQRJDO-BNAHBJSTSA-N 0.000 claims 1
- 241001480043 Arthrodermataceae Species 0.000 claims 1
- 208000001840 Dandruff Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 208000010201 Exanthema Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- IFQSXNOEEPCSLW-DKWTVANSSA-N L-cysteine hydrochloride Chemical compound Cl.SC[C@H](N)C(O)=O IFQSXNOEEPCSLW-DKWTVANSSA-N 0.000 claims 1
- 208000009675 Perioral Dermatitis Diseases 0.000 claims 1
- 240000005049 Prunus salicina Species 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 241001303601 Rosacea Species 0.000 claims 1
- GBFLZEXEOZUWRN-VKHMYHEASA-N S-carboxymethyl-L-cysteine Chemical compound OC(=O)[C@@H](N)CSCC(O)=O GBFLZEXEOZUWRN-VKHMYHEASA-N 0.000 claims 1
- 241000447727 Scabies Species 0.000 claims 1
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 claims 1
- 229960004308 acetylcysteine Drugs 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 229960004399 carbocisteine Drugs 0.000 claims 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 1
- XVOYSCVBGLVSOL-UHFFFAOYSA-N cysteic acid Chemical class OC(=O)C(N)CS(O)(=O)=O XVOYSCVBGLVSOL-UHFFFAOYSA-N 0.000 claims 1
- 229960001305 cysteine hydrochloride Drugs 0.000 claims 1
- 230000037304 dermatophytes Effects 0.000 claims 1
- 235000013399 edible fruits Nutrition 0.000 claims 1
- 201000005884 exanthem Diseases 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 206010037844 rash Diseases 0.000 claims 1
- ZZPKZRHERLGEKA-UHFFFAOYSA-N resorcinol monoacetate Chemical compound CC(=O)OC1=CC=CC(O)=C1 ZZPKZRHERLGEKA-UHFFFAOYSA-N 0.000 claims 1
- 201000004700 rosacea Diseases 0.000 claims 1
- 208000005687 scabies Diseases 0.000 claims 1
- 208000008742 seborrheic dermatitis Diseases 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 230000037067 skin hydration Effects 0.000 claims 1
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Claims (25)
1. Композиция для личной гигиены, содержащая полимерную серу Sn, причем указанная полимерная сера Sn по существу не содержит некосметического масла.
2. Композиция для личной гигиены по п. 1, дополнительно содержащая соединение, содержащее функциональную группу -SH.
3. Композиция для личной гигиены по п. 1, в которой n составляет, по меньшей мере, 9.
4. Композиция для личной гигиены по п. 3, в которой n составляет, по меньшей мере, 100.
5. Композиция для личной гигиены по п. 1, в которой указанная полимерная сера Sn имеет линейную конформацию.
6. Композиция для личной гигиены по п. 2, в которой указанное соединение, содержащее -SH, представляет собой тиолсодержащее соединение.
7. Композиция для личной гигиены по п. 6, в которой указанное тиолсодержащее соединение выбирают из группы, состоящей из аминокислот и тиолсодержащих пептидов.
8. Композиция для личной гигиены по п. 7, в которой указанная аминокислота представляет собой цистеин.
9. Композиция для личной гигиены по п. 8, в которой указанный цистеин выбирают из группы, состоящей из: ацетилцистеина (МНН), N-ацетил-L-цистеина, карбоксиметилцистеина, L-цистеина, N-ацетил-, 2-гидроксибензоата (сложного эфира), L-цистеина, N-ацетил-L-цистеина, N-ацетил-S-[(2E,6E)-3,7,11-триметил-2,6,10-додекатриенил]-L-цистеина, N-(аминоиминометил)-цистеина, DL-L-цистеина, сложного этилового эфира, гидрохлорида (1: 1) цистеина (МНН), L-цистеина, цистеина/экстракта плодов китайской сливы, моногидрохлорида L-цистеина, L-цистеина, S-(карбоксиметил)-ДНК, соли цистеиновой кислоты, N-гуанил-L-цистеина, карбоцистеина оксоацетамида и процистеина.
10. Композиция для личной гигиены по п. 1, в которой pH составляет менее 8.
11. Композиция для личной гигиены по п. 1, которая содержит от около 0,01 до около 20 мас.% серы.
12. Композиция для личной гигиены по п. 1, дополнительно содержащая резорцин.
13. Композиция для личной гигиены по п. 1, дополнительно содержащая растворимую серу.
14. Композиция для личной гигиены по п. 1, дополнительно содержащая активный компонент, который выбирают из группы, состоящей из салициловой кислоты и бензоилпероксида.
15. Способ лечения местных кожных патологий, включающий нанесение на кожу композиции, содержащей полимерную серу Sn, причем указанная полимерная сера Sn по существу не содержит некосметического масла.
16. Способ лечения местных кожных патологий по п. 15, в котором указанная композиция дополнительно содержит соединение, содержащее функциональную группу -SH.
17. Способ лечения местных кожных патологий по п. 16, в котором указанная кожная патология представляет собой acne vulgaris (угри обыкновенные).
18. Способ лечения местных кожных патологий по п. 16, в котором указанная кожная патология представляет собой воспаление.
19. Способ по п. 15, в котором указанный серный компонент содержит растворимую серу и полимерную серу.
20. Способ по п. 15, в котором указанная композиция дополнительно содержит компоненты, активные при лечении угревой сыпи, которые выбирают из группы, состоящей из резорцина, моноацетата резорцина, салициловой кислоты, бензоилпероксида и их комбинации.
21. Способ лечения местных кожных патологий по п. 16, в котором указанная кожная патология представляет собой инфекцию, вызванную микроорганизмом.
22. Способ лечения местных кожных патологий по п. 16, в котором указанная кожная патология входит в группу кожных заболеваний, включающую себорейный дерматит, перхоть, разноцветный лишай, поверхностные дерматофиты, чесотку, розацеа, периоральный дерматит, демодекозные высыпания, псориаз, экзему и атопический дерматит.
23. Способ улучшения функции кожного барьера, включающий местное нанесение на кожу, требующую воздействия на кожный барьер.
24. Способ уменьшения признака старения кожи, включающий местное нанесение на кожу, требующую воздействия на старение кожи.
25. Способ улучшения увлажнения кожи, включающий местное нанесение на кожу, требующую обработки для увлажнения.
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| US14/956,883 | 2015-12-02 | ||
| US14/956,883 US10238685B2 (en) | 2015-12-02 | 2015-12-02 | Compositions containing polymeric sulfur and uses thereof |
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| RU2016146938A true RU2016146938A (ru) | 2018-05-31 |
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| WO2017165615A1 (en) | 2016-03-24 | 2017-09-28 | The Procter & Gamble Company | Hair care compositions comprising malodor reduction compositions |
| CN111278417A (zh) | 2017-10-10 | 2020-06-12 | 宝洁公司 | 含低无机盐的无硫酸盐澄清个人清洁组合物 |
| CA3159404A1 (en) | 2019-12-06 | 2021-06-10 | The Procter & Gamble Company | Sulfate free composition with enhanced deposition of scalp active |
| WO2021173203A1 (en) | 2020-02-27 | 2021-09-02 | The Procter & Gamble Company | Anti-dandruff compositions with sulfur having enhanced efficacy and aesthetics |
| JP2023549517A (ja) | 2020-12-04 | 2023-11-27 | ザ プロクター アンド ギャンブル カンパニー | 悪臭低減物質を含むヘアケア組成物 |
| US11771635B2 (en) | 2021-05-14 | 2023-10-03 | The Procter & Gamble Company | Shampoo composition |
| US11986543B2 (en) | 2021-06-01 | 2024-05-21 | The Procter & Gamble Company | Rinse-off compositions with a surfactant system that is substantially free of sulfate-based surfactants |
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| US2460776A (en) | 1945-11-19 | 1949-02-01 | Noned Corp | Bacteriostatic base for medicinal, cosmetic, and toilet preparations |
| FR2104969B1 (ru) * | 1970-09-11 | 1973-08-10 | Geigy Ag J R | |
| US3755560A (en) | 1971-06-30 | 1973-08-28 | Dow Chemical Co | Nongreasy cosmetic lotions |
| GB1541463A (en) | 1975-10-11 | 1979-02-28 | Lion Dentifrice Co Ltd | Process for prparing a multiple emulsion having a dispersing form of water-phase/oil-phase/water-phase |
| US4192866A (en) | 1978-10-10 | 1980-03-11 | Ralph Anderson | Anorectal medication |
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| US4960764A (en) | 1987-03-06 | 1990-10-02 | Richardson-Vicks Inc. | Oil-in-water-in-silicone emulsion compositions |
| US5100653A (en) * | 1991-02-08 | 1992-03-31 | Giovanni Campo | Topical compositions for treating mouth tissues |
| US5654362A (en) | 1996-03-20 | 1997-08-05 | Dow Corning Corporation | Silicone oils and solvents thickened by silicone elastomers |
| US5919437A (en) | 1996-05-24 | 1999-07-06 | Colgate-Palmolive Company | Cosmetic cream composition containing silicone gel material |
| US6060546A (en) | 1996-09-05 | 2000-05-09 | General Electric Company | Non-aqueous silicone emulsions |
| US5891424A (en) | 1996-10-29 | 1999-04-06 | Procter & Gamble | Antiperspirant cream compositions having improved rheology |
| US5976514A (en) | 1998-11-20 | 1999-11-02 | Procter & Gamble Company | Low-irritation antiperspirant and deodorant compositions containing a volatile, nonpolar hydrocarbon liquid |
| DE19934169A1 (de) | 1999-07-21 | 2001-01-25 | Henkel Kgaa | Kosmetische und/oder dermatologische Zubereitungen |
| US6514489B1 (en) | 2000-06-30 | 2003-02-04 | Medicis Pharmaceutical Corp. | Sulfur containing dermatological compositions and methods for reducing malodors in dermatological compositions |
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| US20080112909A1 (en) * | 2003-06-24 | 2008-05-15 | Ppg Industries Ohio, Inc. | Compositions for providing color to animate objects and related methods |
| US7605194B2 (en) * | 2003-06-24 | 2009-10-20 | Ppg Industries Ohio, Inc. | Aqueous dispersions of polymer-enclosed particles, related coating compositions and coated substrates |
| EP2294123B1 (en) * | 2008-06-30 | 2016-06-01 | Pirelli Tyre S.p.A. | Tyre made of a crosslinkable elastomeric composition comprising an oxetane derivative and an amino acid |
| WO2011044568A1 (en) | 2009-10-09 | 2011-04-14 | Mizell Ligon William | Topical skin cream |
| AU2012308501A1 (en) * | 2011-09-14 | 2014-03-13 | Emory University | Preparation and compositions of highly bioavailable zerovalent sulfur and uses thereof |
| WO2013166585A1 (en) * | 2012-05-07 | 2013-11-14 | University Of Manitoba | Detection and recovery of chemical elements from fluids with tectrabrachion |
| MX2016015907A (es) * | 2014-06-03 | 2018-08-01 | Sulfagenix Inc | Metodos y composiciones para tratar desordenes por deficiencia de oxido nitrico y condiciones relacionadas. |
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| US10238685B2 (en) | 2019-03-26 |
| KR102661585B1 (ko) | 2024-04-30 |
| JP2017101026A (ja) | 2017-06-08 |
| AU2016266017A1 (en) | 2017-06-22 |
| AU2016266017B2 (en) | 2022-09-29 |
| EP3175888B1 (en) | 2021-11-03 |
| BR102016028260B1 (pt) | 2021-10-19 |
| CN106806381A (zh) | 2017-06-09 |
| CA2947705C (en) | 2023-11-07 |
| CA2947705A1 (en) | 2017-06-02 |
| JP6910787B2 (ja) | 2021-07-28 |
| BR102016028260B8 (pt) | 2022-08-09 |
| MX2016015896A (es) | 2018-05-31 |
| RU2016146938A3 (ru) | 2020-03-27 |
| BR102016028260A2 (pt) | 2017-06-06 |
| US20170157170A1 (en) | 2017-06-08 |
| KR20170065004A (ko) | 2017-06-12 |
| MX368814B (es) | 2019-10-17 |
| US20190151355A1 (en) | 2019-05-23 |
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