RU2016141561A3 - - Google Patents
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- RU2016141561A3 RU2016141561A3 RU2016141561A RU2016141561A RU2016141561A3 RU 2016141561 A3 RU2016141561 A3 RU 2016141561A3 RU 2016141561 A RU2016141561 A RU 2016141561A RU 2016141561 A RU2016141561 A RU 2016141561A RU 2016141561 A3 RU2016141561 A3 RU 2016141561A3
- Authority
- RU
- Russia
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Otolaryngology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14001123.0 | 2014-03-26 | ||
| EP14001123 | 2014-03-26 | ||
| PCT/EP2015/056646 WO2015144852A1 (en) | 2014-03-26 | 2015-03-26 | Binding members to tnf alpha |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2016141561A RU2016141561A (ru) | 2018-04-27 |
| RU2016141561A3 true RU2016141561A3 (ru) | 2018-08-23 |
| RU2706551C2 RU2706551C2 (ru) | 2019-11-19 |
Family
ID=50389767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016141561A RU2706551C2 (ru) | 2014-03-26 | 2015-03-26 | Связывающие элементы к фно-альфа |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US10233238B2 (ru) |
| EP (1) | EP3122777B1 (ru) |
| JP (1) | JP6832707B2 (ru) |
| KR (1) | KR20160142849A (ru) |
| CN (1) | CN106414498B (ru) |
| AU (1) | AU2015238261B2 (ru) |
| BR (1) | BR112016022055A2 (ru) |
| CA (1) | CA2943445A1 (ru) |
| ES (1) | ES2858482T3 (ru) |
| IL (1) | IL248000B (ru) |
| MX (1) | MX2016012479A (ru) |
| RU (1) | RU2706551C2 (ru) |
| WO (1) | WO2015144852A1 (ru) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2307457T (pt) * | 2008-06-25 | 2018-10-16 | Esbatech Alcon Biomed Res Unit | Anticorpos estáveis e solúveis que inibem o tnf |
| DK3277719T3 (da) | 2015-03-31 | 2022-05-02 | Sorriso Pharmaceuticals Inc | Polypeptider |
| GB201522394D0 (en) * | 2015-12-18 | 2016-02-03 | Ucb Biopharma Sprl | Antibodies |
| DK3219727T3 (da) * | 2016-03-17 | 2021-01-04 | Tillotts Pharma Ag | Anti-THF-alpha-antistoffer og funktionelle fragmenter deraf |
| PL3219726T3 (pl) | 2016-03-17 | 2021-07-19 | Tillotts Pharma Ag | Przeciwciała anty-tnf alfa i ich funkcjonalne fragmenty |
| MA43716A (fr) * | 2016-03-17 | 2018-11-28 | Numab Innovation Ag | Anticorps anti-tnf et fragments fonctionnels de ceux-ci |
| KR102571700B1 (ko) * | 2016-03-17 | 2023-08-29 | 누맙 세러퓨틱스 아게 | 항TNFα 항체 및 이의 기능성 단편 |
| CN108884156B (zh) * | 2016-03-17 | 2021-10-01 | 努玛创新有限公司 | 抗TNFα抗体及其功能片段 |
| CN106279406B (zh) * | 2016-08-05 | 2019-08-20 | 南京必优康生物技术有限公司 | 猪皮中分离纯化的皮抑素g1的活性成分四连接素及其应用 |
| EP3519438A1 (en) | 2016-09-30 | 2019-08-07 | VHsquared Limited | Compositions |
| EP4424707A2 (en) | 2017-09-19 | 2024-09-04 | Tillotts Pharma AG | Antibody variants |
| CN109627334B (zh) * | 2019-01-29 | 2020-07-17 | 康元医疗科技(大连)有限公司 | 一种纳米抗体、以该纳米抗体为配基的吸附剂及其用途 |
| US20220389092A1 (en) * | 2019-04-05 | 2022-12-08 | The Regents Of The University Of California | Methods and compositions involving chimeric binding polypeptides |
| EP3986931A1 (en) | 2019-06-21 | 2022-04-27 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
| AU2020294980A1 (en) | 2019-06-21 | 2022-02-17 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004283850C1 (en) * | 2003-10-16 | 2011-11-03 | Amgen Research (Munich) Gmbh | Multispecific deimmunized CD3-binders |
| US20060024308A1 (en) * | 2004-07-06 | 2006-02-02 | Roberto Crea | High affinity anti-TNF-alpha antibodies and method |
| EP2172484A3 (en) * | 2005-05-18 | 2010-05-19 | Ablynx N.V. | Serum albumin binding proteins |
| KR101457223B1 (ko) * | 2005-06-07 | 2014-11-04 | 에스바테크 - 어 노바티스 컴파니 엘엘씨 | ＴＮＦα를 억제하는 안정적이고 가용성인 항체 |
| US7331518B2 (en) * | 2006-04-04 | 2008-02-19 | Factortrust, Inc. | Transaction processing systems and methods |
| US9056905B2 (en) * | 2007-05-21 | 2015-06-16 | Alderbio Holdings Llc | Antibodies to TNF-α and use thereof |
| PT2307457T (pt) * | 2008-06-25 | 2018-10-16 | Esbatech Alcon Biomed Res Unit | Anticorpos estáveis e solúveis que inibem o tnf |
| EP2304033B1 (en) * | 2008-06-30 | 2016-09-07 | ESBATech, an Alcon Biomedical Research Unit LLC | Functionalized polypeptides |
| WO2010121140A1 (en) | 2009-04-16 | 2010-10-21 | Facet Biotech Corporation | ANTI-TNF-α ANTIBODIES AND THEIR USES |
| WO2011084714A2 (en) * | 2009-12-17 | 2011-07-14 | Biogen Idec Ma Inc. | STABILIZED ANTI-TNF-ALPHA scFv MOLECULES OR ANTI-TWEAK scFv MOLECULES AND USES THEREOF |
-
2015
- 2015-03-26 EP EP15712626.9A patent/EP3122777B1/en not_active Not-in-force
- 2015-03-26 KR KR1020167029759A patent/KR20160142849A/ko active IP Right Grant
- 2015-03-26 MX MX2016012479A patent/MX2016012479A/es active IP Right Grant
- 2015-03-26 CA CA2943445A patent/CA2943445A1/en active Pending
- 2015-03-26 RU RU2016141561A patent/RU2706551C2/ru active
- 2015-03-26 ES ES15712626T patent/ES2858482T3/es active Active
- 2015-03-26 CN CN201580027869.8A patent/CN106414498B/zh not_active Expired - Fee Related
- 2015-03-26 JP JP2016558349A patent/JP6832707B2/ja not_active Expired - Fee Related
- 2015-03-26 US US15/127,976 patent/US10233238B2/en active Active
- 2015-03-26 WO PCT/EP2015/056646 patent/WO2015144852A1/en active Application Filing
- 2015-03-26 BR BR112016022055A patent/BR112016022055A2/pt not_active Application Discontinuation
- 2015-03-26 AU AU2015238261A patent/AU2015238261B2/en not_active Ceased
-
2016
- 2016-09-25 IL IL248000A patent/IL248000B/en unknown
-
2019
- 2019-01-28 US US16/258,886 patent/US10995138B2/en active Active
-
2021
- 2021-04-23 US US17/238,842 patent/US20210332119A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2706551C2 (ru) | 2019-11-19 |
| CA2943445A1 (en) | 2015-10-01 |
| CN106414498B (zh) | 2020-09-08 |
| US10233238B2 (en) | 2019-03-19 |
| US10995138B2 (en) | 2021-05-04 |
| US20170107282A1 (en) | 2017-04-20 |
| WO2015144852A1 (en) | 2015-10-01 |
| JP6832707B2 (ja) | 2021-02-24 |
| EP3122777A1 (en) | 2017-02-01 |
| EP3122777B1 (en) | 2020-12-23 |
| AU2015238261A1 (en) | 2016-10-06 |
| BR112016022055A2 (pt) | 2017-10-24 |
| CN106414498A (zh) | 2017-02-15 |
| IL248000B (en) | 2021-12-01 |
| US20210332119A1 (en) | 2021-10-28 |
| ES2858482T3 (es) | 2021-09-30 |
| MX2016012479A (es) | 2017-05-23 |
| KR20160142849A (ko) | 2016-12-13 |
| RU2016141561A (ru) | 2018-04-27 |
| US20190144532A1 (en) | 2019-05-16 |
| AU2015238261B2 (en) | 2020-11-19 |
| IL248000A0 (en) | 2016-11-30 |
| JP2017515457A (ja) | 2017-06-15 |