RU2016115929A3 - - Google Patents
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- Publication number
- RU2016115929A3 RU2016115929A3 RU2016115929A RU2016115929A RU2016115929A3 RU 2016115929 A3 RU2016115929 A3 RU 2016115929A3 RU 2016115929 A RU2016115929 A RU 2016115929A RU 2016115929 A RU2016115929 A RU 2016115929A RU 2016115929 A3 RU2016115929 A3 RU 2016115929A3
- Authority
- RU
- Russia
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/72—Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
- C07D303/26—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds having one or more free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310475989.7A CN103508999B (zh) | 2013-10-12 | 2013-10-12 | 马沙骨化醇的合成中间体及其制备方法和用途 |
CN201310475989.7 | 2013-10-12 | ||
PCT/CN2014/088336 WO2015051762A1 (zh) | 2013-10-12 | 2014-10-11 | 马沙骨化醇的合成中间体及其制备方法和用途 |
Publications (3)
Publication Number | Publication Date |
---|---|
RU2016115929A RU2016115929A (ru) | 2017-11-17 |
RU2016115929A3 true RU2016115929A3 (ru) | 2018-03-22 |
RU2650192C2 RU2650192C2 (ru) | 2018-04-11 |
Family
ID=49892479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2016115929A RU2650192C2 (ru) | 2013-10-12 | 2014-10-11 | Синтетическое промежуточное соединение максакальцитола, способ его получения и его применение |
Country Status (8)
Country | Link |
---|---|
US (1) | US20160237030A1 (ru) |
EP (1) | EP3056491B1 (ru) |
JP (1) | JP2016534151A (ru) |
CN (1) | CN103508999B (ru) |
CA (1) | CA2926961C (ru) |
IL (1) | IL245018A (ru) |
RU (1) | RU2650192C2 (ru) |
WO (1) | WO2015051762A1 (ru) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103508999B (zh) * | 2013-10-12 | 2015-05-13 | 浙江海正药业股份有限公司 | 马沙骨化醇的合成中间体及其制备方法和用途 |
CN107176918A (zh) * | 2016-03-09 | 2017-09-19 | 湖南华腾制药有限公司 | 一种马沙骨化醇的纯化方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0078704B1 (en) * | 1981-11-02 | 1987-04-29 | Research Institute For Medicine And Chemistry Inc. | Intermediates in the synthesis of vitamin d derivatives |
JPS6024108A (ja) | 1983-07-18 | 1985-02-06 | 株式会社クボタ | 自動走行作業車 |
EP0227826B1 (en) | 1985-08-02 | 1989-10-25 | Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) | Novel vitamin d analogues |
JP3493037B2 (ja) | 1991-12-18 | 2004-02-03 | 中外製薬株式会社 | 22−オキサコレカルシフェロール誘導体とその製造方法 |
GB9314400D0 (en) * | 1993-07-12 | 1993-08-25 | Leo Pharm Prod Ltd | Produktionsaktieselskab) chemical compounds |
KR20060038352A (ko) * | 1996-09-03 | 2006-05-03 | 더 트러스티스 오브 컬럼비아 유니버시티 인 더 시티 오브 뉴욕 | 비타민 디 및 스테로이드 유도체들의 합성에 사용되는중간체들 |
IT1311923B1 (it) * | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
US7074777B2 (en) | 2000-04-19 | 2006-07-11 | Chugai Seiyaku Kabushiki Kaisha | Vitamin D derivatives |
PL376148A1 (en) * | 2002-10-23 | 2005-12-27 | Leo Pharma A/S | Vitamin d analogues, compositions comprising said analogues and their use |
US20110157322A1 (en) * | 2009-12-31 | 2011-06-30 | Broadcom Corporation | Controlling a pixel array to support an adaptable light manipulator |
JP5563324B2 (ja) * | 2010-02-03 | 2014-07-30 | フォーモサ・ラボラトリーズ・インコーポレーテッド | マキサカルシトール中間体およびその製造方法 |
WO2012122451A2 (en) * | 2011-03-09 | 2012-09-13 | Teva Pharmaceutical Industries Ltd. | Polymorphs of maxacalcitol and process for the preparation of maxacalcitol |
CN102796134B (zh) * | 2012-08-31 | 2015-07-01 | 甘肃皓天化学科技有限公司 | 一种马沙骨化醇中间体的制备方法 |
CN103508999B (zh) * | 2013-10-12 | 2015-05-13 | 浙江海正药业股份有限公司 | 马沙骨化醇的合成中间体及其制备方法和用途 |
-
2013
- 2013-10-12 CN CN201310475989.7A patent/CN103508999B/zh not_active Expired - Fee Related
-
2014
- 2014-10-11 RU RU2016115929A patent/RU2650192C2/ru not_active IP Right Cessation
- 2014-10-11 JP JP2016547216A patent/JP2016534151A/ja not_active Ceased
- 2014-10-11 CA CA2926961A patent/CA2926961C/en not_active Expired - Fee Related
- 2014-10-11 WO PCT/CN2014/088336 patent/WO2015051762A1/zh active Application Filing
- 2014-10-11 EP EP14851652.9A patent/EP3056491B1/en not_active Not-in-force
- 2014-10-11 US US15/028,773 patent/US20160237030A1/en not_active Abandoned
-
2016
- 2016-04-10 IL IL245018A patent/IL245018A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP3056491B1 (en) | 2018-08-08 |
IL245018A (en) | 2017-10-31 |
IL245018A0 (en) | 2016-05-31 |
CA2926961A1 (en) | 2015-04-16 |
WO2015051762A1 (zh) | 2015-04-16 |
JP2016534151A (ja) | 2016-11-04 |
CN103508999A (zh) | 2014-01-15 |
CA2926961C (en) | 2018-12-18 |
CN103508999B (zh) | 2015-05-13 |
RU2650192C2 (ru) | 2018-04-11 |
EP3056491A4 (en) | 2017-04-26 |
EP3056491A1 (en) | 2016-08-17 |
RU2016115929A (ru) | 2017-11-17 |
US20160237030A1 (en) | 2016-08-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20191012 |