RU2015154806A - TSPO translocator protein ligands with antidepressant and nootropic activity - Google Patents
TSPO translocator protein ligands with antidepressant and nootropic activity Download PDFInfo
- Publication number
- RU2015154806A RU2015154806A RU2015154806A RU2015154806A RU2015154806A RU 2015154806 A RU2015154806 A RU 2015154806A RU 2015154806 A RU2015154806 A RU 2015154806A RU 2015154806 A RU2015154806 A RU 2015154806A RU 2015154806 A RU2015154806 A RU 2015154806A
- Authority
- RU
- Russia
- Prior art keywords
- antidepressant
- protein ligands
- translocator protein
- nootropic activity
- tspo
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2015154806A RU2699568C2 (en) | 2015-12-21 | 2015-12-21 | Ligands of translocator protein tspo, having antidepressant and nootropic activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2015154806A RU2699568C2 (en) | 2015-12-21 | 2015-12-21 | Ligands of translocator protein tspo, having antidepressant and nootropic activity |
Publications (3)
Publication Number | Publication Date |
---|---|
RU2015154806A true RU2015154806A (en) | 2017-06-26 |
RU2015154806A3 RU2015154806A3 (en) | 2019-07-17 |
RU2699568C2 RU2699568C2 (en) | 2019-09-06 |
Family
ID=59240405
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2015154806A RU2699568C2 (en) | 2015-12-21 | 2015-12-21 | Ligands of translocator protein tspo, having antidepressant and nootropic activity |
Country Status (1)
Country | Link |
---|---|
RU (1) | RU2699568C2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2757476C2 (en) * | 2020-04-14 | 2021-10-18 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" | Leucyltryptophan tspo ligands with anxiolytic activity |
CN114432455A (en) * | 2022-03-25 | 2022-05-06 | 江苏省人民医院(南京医科大学第一附属医院) | Preparation and application of medicine for treating chronic pain-depression co-disease |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU735401B2 (en) * | 1996-08-28 | 2001-07-05 | Pfizer Inc. | Substituted 6,5-hetero-bicyclic derivatives |
RU2194707C2 (en) * | 2000-04-04 | 2002-12-20 | Научно-исследовательский институт фармакологии РАМН | Pyrrolo[1,2-a]pyrazines or their fumarates showing antiarrhythmic and anti-ischemic activity |
FR2919288B1 (en) * | 2007-07-27 | 2009-09-04 | Sanofi Aventis Sa | 1,2,3,4-TETRAHYDROPYRROLO [1,2-A] PYRAZINE-6-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF |
EP2168963A1 (en) * | 2008-09-25 | 2010-03-31 | Linnea S.A. | Process for the preparation of vinpocetine and apovincamine |
WO2012168697A1 (en) * | 2011-06-06 | 2012-12-13 | Imperial Innovations Limited | Methods to predict binding affinity of tspo imaging agents to tspo |
-
2015
- 2015-12-21 RU RU2015154806A patent/RU2699568C2/en active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2757476C2 (en) * | 2020-04-14 | 2021-10-18 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" | Leucyltryptophan tspo ligands with anxiolytic activity |
CN114432455A (en) * | 2022-03-25 | 2022-05-06 | 江苏省人民医院(南京医科大学第一附属医院) | Preparation and application of medicine for treating chronic pain-depression co-disease |
Also Published As
Publication number | Publication date |
---|---|
RU2015154806A3 (en) | 2019-07-17 |
RU2699568C2 (en) | 2019-09-06 |
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