SG11202100961UA - CONDITIONALLY ACTIVE PROTEINS WITH pH SELECTIVITY - Google Patents
CONDITIONALLY ACTIVE PROTEINS WITH pH SELECTIVITYInfo
- Publication number
- SG11202100961UA SG11202100961UA SG11202100961UA SG11202100961UA SG11202100961UA SG 11202100961U A SG11202100961U A SG 11202100961UA SG 11202100961U A SG11202100961U A SG 11202100961UA SG 11202100961U A SG11202100961U A SG 11202100961UA SG 11202100961U A SG11202100961U A SG 11202100961UA
- Authority
- SG
- Singapore
- Prior art keywords
- selectivity
- active proteins
- conditionally active
- conditionally
- proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862720570P | 2018-08-21 | 2018-08-21 | |
| PCT/US2019/047165 WO2020041247A1 (en) | 2018-08-21 | 2019-08-20 | CONDITIONALLY ACTIVE PROTEINS WITH pH SELECTIVITY |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202100961UA true SG11202100961UA (en) | 2021-03-30 |
Family
ID=69591164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202100961UA SG11202100961UA (en) | 2018-08-21 | 2019-08-20 | CONDITIONALLY ACTIVE PROTEINS WITH pH SELECTIVITY |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20210309742A1 (en) |
| EP (1) | EP3841118A4 (en) |
| JP (1) | JP2021534194A (en) |
| KR (1) | KR20210041604A (en) |
| CN (1) | CN112566929A (en) |
| AU (1) | AU2019326407A1 (en) |
| CA (1) | CA3107161A1 (en) |
| MX (1) | MX2021002057A (en) |
| SG (1) | SG11202100961UA (en) |
| TW (1) | TW202018087A (en) |
| WO (1) | WO2020041247A1 (en) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX338098B (en) * | 2009-03-09 | 2016-04-01 | Bioatla Llc | Mirac proteins. |
| US9969813B2 (en) * | 2012-05-10 | 2018-05-15 | Bioatla, Llc | Multi-specific monoclonal antibodies |
| MX2016014824A (en) * | 2014-05-13 | 2017-03-23 | Bioatla Llc | Conditionally active biological proteins. |
| EP3189152A4 (en) * | 2014-09-03 | 2018-04-04 | BioAtla LLC | Discovering and producing conditionally active biologic proteins in the same eukaryotic cell production hosts |
| FR3035879A1 (en) * | 2015-05-07 | 2016-11-11 | Lab Francais Du Fractionnement | MUTANTS FC WITH MODIFIED FUNCTIONAL ACTIVITY |
| JP7064769B2 (en) * | 2015-11-02 | 2022-05-11 | バイオアトラ、エルエルシー | Conditionally active polypeptide |
| AU2017320874B2 (en) * | 2016-08-31 | 2024-03-07 | Bioatla, Llc | Conditionally active polypeptides and methods of generating them |
-
2019
- 2019-08-20 KR KR1020217007040A patent/KR20210041604A/en active Search and Examination
- 2019-08-20 CA CA3107161A patent/CA3107161A1/en active Pending
- 2019-08-20 US US17/264,702 patent/US20210309742A1/en active Pending
- 2019-08-20 AU AU2019326407A patent/AU2019326407A1/en active Pending
- 2019-08-20 MX MX2021002057A patent/MX2021002057A/en unknown
- 2019-08-20 CN CN201980051029.3A patent/CN112566929A/en active Pending
- 2019-08-20 EP EP19851604.9A patent/EP3841118A4/en active Pending
- 2019-08-20 JP JP2021509752A patent/JP2021534194A/en active Pending
- 2019-08-20 SG SG11202100961UA patent/SG11202100961UA/en unknown
- 2019-08-20 WO PCT/US2019/047165 patent/WO2020041247A1/en unknown
- 2019-08-21 TW TW108129801A patent/TW202018087A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020041247A1 (en) | 2020-02-27 |
| JP2021534194A (en) | 2021-12-09 |
| CA3107161A1 (en) | 2020-02-27 |
| EP3841118A1 (en) | 2021-06-30 |
| CN112566929A (en) | 2021-03-26 |
| TW202018087A (en) | 2020-05-16 |
| US20210309742A1 (en) | 2021-10-07 |
| MX2021002057A (en) | 2021-07-21 |
| EP3841118A4 (en) | 2022-05-25 |
| KR20210041604A (en) | 2021-04-15 |
| AU2019326407A1 (en) | 2021-02-18 |
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| SG11202100961UA (en) | CONDITIONALLY ACTIVE PROTEINS WITH pH SELECTIVITY |