RU2013129711A - ANTIDIABETIC ACTIVITY SUBSTANCES - Google Patents

ANTIDIABETIC ACTIVITY SUBSTANCES Download PDF

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Publication number
RU2013129711A
RU2013129711A RU2013129711/15A RU2013129711A RU2013129711A RU 2013129711 A RU2013129711 A RU 2013129711A RU 2013129711/15 A RU2013129711/15 A RU 2013129711/15A RU 2013129711 A RU2013129711 A RU 2013129711A RU 2013129711 A RU2013129711 A RU 2013129711A
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RU
Russia
Prior art keywords
antidiabetic activity
monosuccinyl
dipeptide
dimeric
lysine
Prior art date
Application number
RU2013129711/15A
Other languages
Russian (ru)
Other versions
RU2613314C2 (en
Inventor
Сергей Борисович Середенин
Татьяна Александровна Гудашева
Рита Ушеровна Островская
Полина Юрьевна Поварнина
Ирина Витальевна Озерова
Original Assignee
Федеральное государственное бюджетное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" Российской академии медицинских наук
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Application filed by Федеральное государственное бюджетное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" Российской академии медицинских наук filed Critical Федеральное государственное бюджетное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" Российской академии медицинских наук
Priority to RU2013129711A priority Critical patent/RU2613314C2/en
Publication of RU2013129711A publication Critical patent/RU2013129711A/en
Application granted granted Critical
Publication of RU2613314C2 publication Critical patent/RU2613314C2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides

Abstract

1. Применение димерного дипептида ГК-2 Rat(r) (гексаметилендиамид бис-(N-моносукцинил-глутамил-лизина)) в качестве вещества, обладающего антидиабетической активностью.2. Применение димерного дипептида ГК-2 Human(h) (гексаметилендиамид бис-(N-моносукцинил-глицил-L-лизина)) в качестве вещества, обладающего антидиабетической активностью.1. The use of the dimeric dipeptide GK-2 Rat (r) (hexamethylene diamide bis- (N-monosuccinyl-glutamyl-lysine)) as a substance with antidiabetic activity. 2. The use of the dimeric dipeptide GK-2 Human (h) (hexamethylene diamide bis- (N-monosuccinyl-glycyl-L-lysine)) as a substance with antidiabetic activity.

Claims (2)

1. Применение димерного дипептида ГК-2 Rat(r) (гексаметилендиамид бис-(N-моносукцинил-глутамил-лизина)) в качестве вещества, обладающего антидиабетической активностью.1. The use of the dimeric dipeptide GK-2 Rat (r) (hexamethylene diamide bis- (N-monosuccinyl-glutamyl-lysine)) as a substance with antidiabetic activity. 2. Применение димерного дипептида ГК-2 Human(h) (гексаметилендиамид бис-(N-моносукцинил-глицил-L-лизина)) в качестве вещества, обладающего антидиабетической активностью. 2. The use of the dimeric dipeptide GK-2 Human (h) (hexamethylene diamide bis- (N-monosuccinyl-glycyl-L-lysine)) as a substance with antidiabetic activity.
RU2013129711A 2013-06-28 2013-06-28 Small molecules with ngf-like activity and antidiabetic properties RU2613314C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2013129711A RU2613314C2 (en) 2013-06-28 2013-06-28 Small molecules with ngf-like activity and antidiabetic properties

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2013129711A RU2613314C2 (en) 2013-06-28 2013-06-28 Small molecules with ngf-like activity and antidiabetic properties

Publications (2)

Publication Number Publication Date
RU2013129711A true RU2013129711A (en) 2015-01-10
RU2613314C2 RU2613314C2 (en) 2017-03-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2013129711A RU2613314C2 (en) 2013-06-28 2013-06-28 Small molecules with ngf-like activity and antidiabetic properties

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Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2141483C1 (en) * 1997-07-04 1999-11-20 Небольсин Владимир Евгеньевич Peptide derivatives or their pharmaceutically acceptable salts, method of their synthesis, use and pharmaceutical composition
AUPQ084899A0 (en) * 1999-06-08 1999-07-01 University Of Melbourne, The Neurotrophin agonists
RU2242241C1 (en) * 2003-12-10 2004-12-20 Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" Tetrapeptide regulating glucose level in diabetes mellitus, pharmacological agent based on thereof and method for its applying
RU2410392C2 (en) * 2009-02-16 2011-01-27 Учреждение Российской академии медицинских наук Научно-исследовательский институт фармакологии имени В.В. Закусова РАМН Dipeptide mimetics of ngf and bdnf neurotrophins

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RU2613314C2 (en) 2017-03-15

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