RU2015134205A - Модульная аналитическая система - Google Patents

Модульная аналитическая система Download PDF

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RU2015134205A
RU2015134205A RU2015134205A RU2015134205A RU2015134205A RU 2015134205 A RU2015134205 A RU 2015134205A RU 2015134205 A RU2015134205 A RU 2015134205A RU 2015134205 A RU2015134205 A RU 2015134205A RU 2015134205 A RU2015134205 A RU 2015134205A
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analysis
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installation according
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ВОН Др. Кен ЧЖИ
Дейвид Хью УИЛЛЬЯМС
Айан МАКЕЛАРНИ
Элизабет ДЖИЛЛИС
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Маст Груп Лимитед
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/46—Measurement of colour; Colour measuring devices, e.g. colorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J5/00—Radiation pyrometry, e.g. infrared or optical thermometry
    • G01J5/60—Radiation pyrometry, e.g. infrared or optical thermometry using determination of colour temperature
    • G01J5/605—Radiation pyrometry, e.g. infrared or optical thermometry using determination of colour temperature using visual determination
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/46—Measurement of colour; Colour measuring devices, e.g. colorimeters
    • G01J2003/466—Coded colour; Recognition of predetermined colour; Determining proximity to predetermined colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N2035/00178—Special arrangements of analysers
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    • G—PHYSICS
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    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00821—Identification of carriers, materials or components in automatic analysers nature of coded information
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N2035/00821—Identification of carriers, materials or components in automatic analysers nature of coded information
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    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
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    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G01N2035/0441—Rotary sample carriers, i.e. carousels for samples
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  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Claims (21)

1. Установка для проведения множественных анализов, содержащая:
несколько аналитических устройств, каждое из которых выполнено с возможностью загрузки в него анализируемого образца, и каждое из которых несет идентификатор для отображения одной или нескольких следующих составляющих информации: вид проводимого анализа или испытания; или директивная информация или параметры, которых нужно придерживаться при выполнении испытания; или идентификационная информация о данном образце; или другие инструкции;
несколько аналитических блоков, каждый из которых выполнен с возможностью установки в него одного из аналитических устройств и перемещения этого аналитического устройства для проведения анализа; и
контроллер для взаимодействия с аналитическими блоками, выполненный с возможностью независимого управления каждым анализом согласно информации, обеспеченной каждым идентификатором.
2. Установка по п. 1, в которой аналитическое устройство имеет вид аналитического диска, а аналитический блок обеспечивает вращательное движение аналитического диска для выполнения анализа.
3. Установка по п. 1, в которой идентификатор физически прикреплен к аналитическому устройству или объединен с ним.
4. Установка по п. 1, в которой идентификатор представляет собой штрих-код или радиочастотную метку.
5. Установка по п. 1, содержащая средство считывания идентификатора и передачи этой информации в контроллер.
6. Установка по п. 1, в которой каждый аналитический блок содержит оптический детектор, используемый при анализе, и, опционально, в которой оптический детектор выполнен с возможностью регистрации флуоресцентного выхода от анализа или с возможностью распознавания цвета, опционально, красного, зеленого и (или) синего.
7. Установка по п. 1, содержащая группу аналитических блоков, скомпонованных в одну или несколько стоек, в которых соседние блоки установлены один поверх другого.
8. Установка по п. 1, содержащая источник питания.
9. Установка по п. 1, в которой аналитические блоки выполнены с возможностью установки потребителем таким образом, чтобы при введении дополнительного аналитического блока автоматически обеспечивалось взаимное соединение между аналитическими блоками и функциональное соединение с контроллером.
10. Аналитический блок, приспособленный для использования в установке по п. 9.
11. Аналитическое устройство, приспособленное для использования в установке по п. 2.
12. Способ проведения анализа образца, при выполнении которого:
загружают образец в аналитическое устройство, несущее идентификатор для отображения одной или нескольких следующих составляющих информации: вид проводимого анализа или испытания; или директивную информацию или параметры, которых нужно придерживаться при проведении испытания; или идентификационную информацию о данном образце; или другие инструкции;
используют считывающее средство для считывания идентификатора и передачи указанной информации в контроллер, взаимодействующий с аналитическим блоком, выполненным с возможностью размещения в нем аналитического устройства и придания движения аналитическому устройству при выполнении анализа; и
помещают аналитическое устройство в аналитический блок и обеспечивают выполнение аналитическим устройством анализа в соответствии с информацией, обеспеченной идентификатором.
13. Способ по п. 12, в котором аналитическое устройство имеет вид аналитического диска, а аналитический блок способен придавать вращательное движение аналитическому диску для управления анализом.
14. Способ по п. 12, в котором идентификатор представляет собой штрих-код или радиочастотную метку.
15. Способ по п. 12, включающий использование оптического детектора для интерпретации результатов анализа, опционально, в котором оптический детектор способен регистрировать флуоресцентный выход от анализа или распознавать цвета, опционально, красный, зеленый и (или) синий.
RU2015134205A 2013-01-16 2014-01-16 Модульная аналитическая система RU2730841C2 (ru)

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GB1300813.1A GB2512564B (en) 2013-01-16 2013-01-16 Modular assay system
PCT/GB2014/050124 WO2014111719A1 (en) 2013-01-16 2014-01-16 Modular assay system

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US20150362431A1 (en) 2015-12-17
RU2730841C2 (ru) 2020-08-26
CA2898136C (en) 2023-05-23
CA2898136A1 (en) 2014-07-24
US10908085B2 (en) 2021-02-02
WO2014111719A1 (en) 2014-07-24
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EP2946215A1 (en) 2015-11-25
ZA201505256B (en) 2017-11-29
ES2893398T3 (es) 2022-02-09
AU2018202142A1 (en) 2018-04-19
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AU2014206681A1 (en) 2015-08-06

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