RU2013107132A - METHOD FOR DETERMINING THE EXPRESSION OF MODIFICATION ACTIVITY ASSOCIATED WITH A CARRIER - Google Patents
METHOD FOR DETERMINING THE EXPRESSION OF MODIFICATION ACTIVITY ASSOCIATED WITH A CARRIER Download PDFInfo
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- RU2013107132A RU2013107132A RU2013107132/15A RU2013107132A RU2013107132A RU 2013107132 A RU2013107132 A RU 2013107132A RU 2013107132/15 A RU2013107132/15 A RU 2013107132/15A RU 2013107132 A RU2013107132 A RU 2013107132A RU 2013107132 A RU2013107132 A RU 2013107132A
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- carrier
- starting material
- molecules
- substance
- modifying
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
1. Способ определения выраженности модифицирующей активности, ассоциированной с носителем, приобретенной в процессе технологической обработки исходного вещества в виде многократного последовательного уменьшения концентрации последнего с использованием носителя, которая проявляется в способности непосредственно изменять физико-химические и/или биологические свойства исходного вещества при воздействии на него указанным носителем, характеризующийся тем, что аналитическими методами определяют наличие или отсутствие молекул исходного вещества в указанном носителе и измеряют аналитическими методами один или несколько характерных параметров исходного вещества до и после взаимодействия с ним указанного носителя, при этом степень выраженности модифицирующей активности определяют по величине изменения характерного параметра в относительных единицах.2. Способ по п.1, характеризующийся тем, что при наличии в модифицированном растворителе молекул исходного вещества перед измерением характерного параметра исходного вещества при взаимодействии с ним указанного носителя из последнего удаляют молекулы исходного вещества.3. Способ по п.1, характеризующийся тем, что в качестве носителя используют жидкий растворитель.4. Способ по п.1 или 2, характеризующийся тем, что в качестве носителя используют твердый носитель.5. Способ по п.1 или 2, характеризующийся тем, что дополнительно регистрируют аналитическими методами влияние на физико-химические свойства исходного вещества неактивированного носителя и/или другого вещества, которые обработаны путем многократного последовательного разведения или тритурации с пр1. A method for determining the severity of modifying activity associated with a carrier acquired during technological processing of a starting substance in the form of a multiple successive decrease in the concentration of the starting material using the carrier, which manifests itself in the ability to directly change the physicochemical and / or biological properties of the starting material when exposed to it the specified carrier, characterized in that analytical methods determine the presence or absence of molecules of the original th substance in said medium and is measured by analytical methods, one or more characteristic parameters of the starting material before and after the interaction with it said carrier, wherein the degree of activity is determined by modifying the amount of change in characteristic parameter relative edinitsah.2. The method according to claim 1, characterized in that in the presence of molecules of the starting material in the modified solvent, before measuring the characteristic parameter of the starting material, when interacting with said carrier, the molecules of the starting material are removed from the latter. The method according to claim 1, characterized in that a liquid solvent is used as a carrier. The method according to claim 1 or 2, characterized in that a solid carrier is used as the carrier. The method according to claim 1 or 2, characterized in that the analytic methods additionally record the effect on the physicochemical properties of the starting material of an inactive carrier and / or other substance, which are processed by repeated serial dilution or trituration with
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2013107132A RU2643934C2 (en) | 2013-02-19 | 2013-02-19 | Method for determining expression of the modifying activity associated with carrier |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2013107132A RU2643934C2 (en) | 2013-02-19 | 2013-02-19 | Method for determining expression of the modifying activity associated with carrier |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2013107132A true RU2013107132A (en) | 2014-08-27 |
RU2643934C2 RU2643934C2 (en) | 2018-02-06 |
Family
ID=51455948
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2013107132A RU2643934C2 (en) | 2013-02-19 | 2013-02-19 | Method for determining expression of the modifying activity associated with carrier |
Country Status (1)
Country | Link |
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RU (1) | RU2643934C2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2768221C1 (en) | 2021-06-10 | 2022-03-23 | Общество С Ограниченной Ответственностью "Научно-Производственная Фирма "Материа Медика Холдинг" | Modifier and method for changing the electrophysical and magnetic properties of ceramics |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2161955C1 (en) * | 1999-07-16 | 2001-01-20 | Эпштейн Олег Ильич | Method of varying physico-chemical and biological properties of substance |
RU2195648C2 (en) * | 2000-11-03 | 2002-12-27 | Эпштейн Олег Ильич | Method of qualitative determination of homeopathic medicinal preparation or potentiated form of substance |
RU2009106496A (en) * | 2009-02-24 | 2010-08-27 | Учреждение Российской академии наук Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра РАН (ИОФХ им. | METHOD FOR FORECASTING THE BIOEFFECT OF SOLUTIONS OF LOW AND SUPERLOW CONCENTRATIONS |
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2013
- 2013-02-19 RU RU2013107132A patent/RU2643934C2/en not_active Application Discontinuation
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Publication number | Publication date |
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RU2643934C2 (en) | 2018-02-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20160302 |
|
FZ9A | Application not withdrawn (correction of the notice of withdrawal) |
Effective date: 20170314 |