RU2009106496A - METHOD FOR FORECASTING THE BIOEFFECT OF SOLUTIONS OF LOW AND SUPERLOW CONCENTRATIONS - Google Patents

METHOD FOR FORECASTING THE BIOEFFECT OF SOLUTIONS OF LOW AND SUPERLOW CONCENTRATIONS Download PDF

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Publication number
RU2009106496A
RU2009106496A RU2009106496/15A RU2009106496A RU2009106496A RU 2009106496 A RU2009106496 A RU 2009106496A RU 2009106496/15 A RU2009106496/15 A RU 2009106496/15A RU 2009106496 A RU2009106496 A RU 2009106496A RU 2009106496 A RU2009106496 A RU 2009106496A
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RU
Russia
Prior art keywords
solutions
physicochemical parameters
bioeffect
nanoassociates
sizes
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Application number
RU2009106496/15A
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Russian (ru)
Inventor
Александр Иванович Коновалов (RU)
Александр Иванович Коновалов
Ирина Сергеевна Рыжкина (RU)
Ирина Сергеевна Рыжкина
Ляйсан Ильсуровна Муртазина (RU)
Ляйсан Ильсуровна Муртазина
Original Assignee
Учреждение Российской академии наук Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра РАН (ИОФХ им.
Учреждение Российской академии наук Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра РАН (ИОФХ им. А.Е. Арбузова КазНЦ РАН)
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Application filed by Учреждение Российской академии наук Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра РАН (ИОФХ им., Учреждение Российской академии наук Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра РАН (ИОФХ им. А.Е. Арбузова КазНЦ РАН) filed Critical Учреждение Российской академии наук Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра РАН (ИОФХ им.
Priority to RU2009106496/15A priority Critical patent/RU2009106496A/en
Publication of RU2009106496A publication Critical patent/RU2009106496A/en

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Abstract

1. Способ прогнозирования биоэффекта в растворах низких и сверхнизких концентраций, включающий приготовление водных растворов исследуемого вещества в широкой области концентраций, определение размеров наноассоциатов в приготовленных растворах с фиксированной концентрацией вещества, измерение физико-химических параметров этих растворов, построение графической зависимости изменения физико-химических параметров и размеров наноассоциатов от концентраций, определение концентрационных интервалов возможного проявления биоэффекта по наличию на концентрационных графических зависимостях размеров наноассоциатов и физико-химических параметров нелинейных полимодальных участков. ! 2. Способ по п.1, где физико-химическими параметрами растворов являются электропроводность, рН, поверхностное натяжение. 1. A method for predicting the bioeffect in solutions of low and ultra-low concentrations, including the preparation of aqueous solutions of the test substance in a wide concentration range, the determination of the sizes of nanoassociates in the prepared solutions with a fixed concentration of the substance, the measurement of the physicochemical parameters of these solutions, the construction of a graphical dependence of the change in physicochemical parameters and sizes of nanoassociates from concentrations, determination of concentration intervals of the possible manifestation of bioeffect by the presence on the concentration graphical dependencies of the sizes of nanoassociates and physicochemical parameters of nonlinear polymodal sections. ! 2. The method according to claim 1, where the physicochemical parameters of the solutions are electrical conductivity, pH, surface tension.

Claims (2)

1. Способ прогнозирования биоэффекта в растворах низких и сверхнизких концентраций, включающий приготовление водных растворов исследуемого вещества в широкой области концентраций, определение размеров наноассоциатов в приготовленных растворах с фиксированной концентрацией вещества, измерение физико-химических параметров этих растворов, построение графической зависимости изменения физико-химических параметров и размеров наноассоциатов от концентраций, определение концентрационных интервалов возможного проявления биоэффекта по наличию на концентрационных графических зависимостях размеров наноассоциатов и физико-химических параметров нелинейных полимодальных участков.1. A method for predicting the bioeffect in solutions of low and ultra-low concentrations, including the preparation of aqueous solutions of the test substance in a wide concentration range, the determination of the sizes of nanoassociates in the prepared solutions with a fixed concentration of the substance, the measurement of the physicochemical parameters of these solutions, the construction of a graphical dependence of the change in physicochemical parameters and sizes of nanoassociates from concentrations, determination of concentration intervals of the possible manifestation of bioeffect by the presence on the concentration graphical dependencies of the sizes of nanoassociates and physicochemical parameters of nonlinear polymodal sections. 2. Способ по п.1, где физико-химическими параметрами растворов являются электропроводность, рН, поверхностное натяжение. 2. The method according to claim 1, where the physicochemical parameters of the solutions are electrical conductivity, pH, surface tension.
RU2009106496/15A 2009-02-24 2009-02-24 METHOD FOR FORECASTING THE BIOEFFECT OF SOLUTIONS OF LOW AND SUPERLOW CONCENTRATIONS RU2009106496A (en)

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RU2009106496/15A RU2009106496A (en) 2009-02-24 2009-02-24 METHOD FOR FORECASTING THE BIOEFFECT OF SOLUTIONS OF LOW AND SUPERLOW CONCENTRATIONS

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2643936C2 (en) * 2013-02-19 2018-02-06 Олег Ильич Эпштейн Method for determination of expression of modifying activity associated with carrier
RU2643934C2 (en) * 2013-02-19 2018-02-06 Олег Ильич Эпштейн Method for determining expression of the modifying activity associated with carrier

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2643936C2 (en) * 2013-02-19 2018-02-06 Олег Ильич Эпштейн Method for determination of expression of modifying activity associated with carrier
RU2643934C2 (en) * 2013-02-19 2018-02-06 Олег Ильич Эпштейн Method for determining expression of the modifying activity associated with carrier

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