RU2012155121A - Новое средство, устройства и способы - Google Patents
Новое средство, устройства и способы Download PDFInfo
- Publication number
- RU2012155121A RU2012155121A RU2012155121/10A RU2012155121A RU2012155121A RU 2012155121 A RU2012155121 A RU 2012155121A RU 2012155121/10 A RU2012155121/10 A RU 2012155121/10A RU 2012155121 A RU2012155121 A RU 2012155121A RU 2012155121 A RU2012155121 A RU 2012155121A
- Authority
- RU
- Russia
- Prior art keywords
- seq
- molecular weight
- low molecular
- fragment
- derivative
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 8
- 229920001184 polypeptide Polymers 0.000 claims abstract 14
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract 14
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract 14
- 102000004169 proteins and genes Human genes 0.000 claims abstract 14
- 108090000623 proteins and genes Proteins 0.000 claims abstract 14
- 238000000926 separation method Methods 0.000 claims abstract 12
- 239000013060 biological fluid Substances 0.000 claims abstract 9
- 239000000758 substrate Substances 0.000 claims abstract 8
- 102100031096 Cubilin Human genes 0.000 claims abstract 7
- 108010003082 intrinsic factor-cobalamin receptor Proteins 0.000 claims abstract 7
- 125000003275 alpha amino acid group Chemical group 0.000 claims abstract 6
- 239000008280 blood Substances 0.000 claims abstract 6
- 210000004369 blood Anatomy 0.000 claims abstract 6
- 239000003795 chemical substances by application Substances 0.000 claims abstract 5
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims abstract 2
- 108010015372 Low Density Lipoprotein Receptor-Related Protein-2 Proteins 0.000 claims abstract 2
- 102100021922 Low-density lipoprotein receptor-related protein 2 Human genes 0.000 claims abstract 2
- 239000012634 fragment Substances 0.000 claims 10
- 238000000502 dialysis Methods 0.000 claims 2
- 238000001914 filtration Methods 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000013463 Immunoglobulin Light Chains Human genes 0.000 claims 1
- 108010065825 Immunoglobulin Light Chains Proteins 0.000 claims 1
- 238000001631 haemodialysis Methods 0.000 claims 1
- 230000000322 hemodialysis Effects 0.000 claims 1
- 238000002615 hemofiltration Methods 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 claims 1
- 239000000813 peptide hormone Substances 0.000 claims 1
- 102000028728 vitamin binding proteins Human genes 0.000 claims 1
- 108091009357 vitamin binding proteins Proteins 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3403—Regulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
- B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/06—Peptides being immobilised on, or in, an organic carrier attached to the carrier via a bridging agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- External Artificial Organs (AREA)
- Peptides Or Proteins (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35723110P | 2010-06-22 | 2010-06-22 | |
| EP10166799 | 2010-06-22 | ||
| EP10166799.6 | 2010-06-22 | ||
| US61/357,231 | 2010-06-22 | ||
| PCT/EP2011/060130 WO2011161017A1 (en) | 2010-06-22 | 2011-06-17 | New medium, devices and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012155121A true RU2012155121A (ru) | 2014-07-27 |
Family
ID=42989310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012155121/10A RU2012155121A (ru) | 2010-06-22 | 2011-06-17 | Новое средство, устройства и способы |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20130098834A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2585489A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2013532031A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103025762A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011269156A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2802971A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2012015253A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ604034A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2012155121A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011161017A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3102224B1 (en) * | 2013-12-20 | 2019-02-20 | NephroGenesis, LLC. | Apparatuses for kidney dialysis and lipocalin protein for use in the prevention or treatment of uremia by dialysis |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7498994A (en) * | 1993-08-10 | 1995-02-28 | Ao Forschungsinstitut Davos | Treatment of tumors by selective protein depletion |
| JPH09266948A (ja) * | 1996-01-31 | 1997-10-14 | Kanegafuchi Chem Ind Co Ltd | 血液浄化器および血液浄化装置 |
| AU2462399A (en) | 1998-01-22 | 1999-08-09 | Institut National De La Sante Et De La Recherche Medicale | Cubilin protein, dna sequences encoding cubilin and uses thereof |
| US6992171B2 (en) * | 2000-06-22 | 2006-01-31 | Takeda Pharmaceutical Company Limited | Polypeptide and its DNA |
| US20040235161A1 (en) | 2001-05-17 | 2004-11-25 | Yasuhiko Tabata | Artificial kidney having function of metabolizing protein and method of constructing the same |
| WO2002099438A2 (en) * | 2001-06-07 | 2002-12-12 | Max-Delbrueck-Centrum Für Molekulare Medizin | Modulation of steroid hormone uptake |
| AU2002307802A1 (en) * | 2002-04-25 | 2003-10-08 | Recepticon Aps | Antagonists of megalin or cubilin for use in preventing organ damage induced by therapeutic agents |
| WO2003102593A1 (en) | 2002-05-31 | 2003-12-11 | Pfizer Products Inc. | Methods for avoiding renal injury |
| EP1583770A4 (en) * | 2002-12-20 | 2006-10-18 | Applera Corp | STENOSIS-ASSOCIATED GENETIC POLYMORPHIA, DETECTION METHOD AND ITS USE |
| US20090110720A1 (en) * | 2004-10-06 | 2009-04-30 | Anders Nykjaer | Use of compounds for the prevention of drug-induced cell toxicity |
-
2011
- 2011-06-17 CA CA2802971A patent/CA2802971A1/en not_active Abandoned
- 2011-06-17 US US13/805,810 patent/US20130098834A1/en not_active Abandoned
- 2011-06-17 RU RU2012155121/10A patent/RU2012155121A/ru not_active Application Discontinuation
- 2011-06-17 NZ NZ604034A patent/NZ604034A/en not_active IP Right Cessation
- 2011-06-17 JP JP2013515822A patent/JP2013532031A/ja active Pending
- 2011-06-17 WO PCT/EP2011/060130 patent/WO2011161017A1/en not_active Ceased
- 2011-06-17 MX MX2012015253A patent/MX2012015253A/es not_active Application Discontinuation
- 2011-06-17 CN CN2011800300119A patent/CN103025762A/zh active Pending
- 2011-06-17 AU AU2011269156A patent/AU2011269156A1/en not_active Abandoned
- 2011-06-17 EP EP11726415.0A patent/EP2585489A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CA2802971A1 (en) | 2011-12-29 |
| EP2585489A1 (en) | 2013-05-01 |
| WO2011161017A1 (en) | 2011-12-29 |
| NZ604034A (en) | 2014-07-25 |
| MX2012015253A (es) | 2013-10-01 |
| US20130098834A1 (en) | 2013-04-25 |
| AU2011269156A1 (en) | 2013-01-10 |
| JP2013532031A (ja) | 2013-08-15 |
| CN103025762A (zh) | 2013-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA94 | Acknowledgement of application withdrawn (non-payment of fees) |
Effective date: 20151207 |