RU2008133088A - METHOD FOR REPRODUCING A MALIGNANT PROCESS IN AN EXPERIMENT - Google Patents
METHOD FOR REPRODUCING A MALIGNANT PROCESS IN AN EXPERIMENT Download PDFInfo
- Publication number
- RU2008133088A RU2008133088A RU2008133088/14A RU2008133088A RU2008133088A RU 2008133088 A RU2008133088 A RU 2008133088A RU 2008133088/14 A RU2008133088/14 A RU 2008133088/14A RU 2008133088 A RU2008133088 A RU 2008133088A RU 2008133088 A RU2008133088 A RU 2008133088A
- Authority
- RU
- Russia
- Prior art keywords
- tumor
- sterile
- transferred
- saline
- reproducing
- Prior art date
Links
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Способ воспроизведения злокачественного процесса в эксперименте, включающий перевивку опухоли, отличающийся тем, что на 14-21 сутки от момента перевивки саркомы С-45 самцам белых беспородных крыс, одно животное забивают, в боксе извлекают опухоль стерильными инструментами, соединительнотканную капсулу отделяют, выбирают кусочек жизнеспособной ткани серовато-розового цвета и переносят в стерильную чашку Петри, ополаскивают физиологическим раствором и переносят в стерильный гомогенизатор, опухоль измельчают, полученную опухолевую кашицу разводят стерильным физиологическим раствором в отношении 1:5 по объему, и набирают в стерильный шприц, самцов белых беспородных крыс фиксируют на спине и вводят опухолевую взвесь с соблюдением правил асептики в подключичную вену в дозе 0,5 мл.A method for reproducing a malignant process in an experiment, including transplanting a tumor, characterized in that on 14-21 days from the moment of transplantation of S-45 sarcoma to male white outbred rats, one animal is killed, the tumor is removed with sterile instruments in the box, the connective tissue capsule is separated, a piece of viable is selected grayish pink tissue and transferred to a sterile Petri dish, rinsed with saline and transferred to a sterile homogenizer, the tumor is crushed, the resulting tumor gruel diluted with sterile saline to 1: 5 by volume, and drawn into a sterile syringe, male albino rats were fixed on their backs and administered tumor suspension aseptically into the subclavian vein in a dose of 0.5 ml.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2008133088/14A RU2388064C1 (en) | 2008-08-11 | 2008-08-11 | Method for simulation of malignant process in experiment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2008133088/14A RU2388064C1 (en) | 2008-08-11 | 2008-08-11 | Method for simulation of malignant process in experiment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2008133088A true RU2008133088A (en) | 2010-02-20 |
| RU2388064C1 RU2388064C1 (en) | 2010-04-27 |
Family
ID=42126700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008133088/14A RU2388064C1 (en) | 2008-08-11 | 2008-08-11 | Method for simulation of malignant process in experiment |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2388064C1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2676641C1 (en) * | 2018-04-05 | 2019-01-09 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Method of stimulating chronic pain of malignant growth in lung rats |
| RU2743960C1 (en) * | 2020-07-02 | 2021-03-01 | федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии" Министерства здравоохранения Российской Федерации | Method of modifying the development of adenocarcinoma experimentally |
| RU2751930C1 (en) * | 2021-01-20 | 2021-07-20 | федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр онкологии» Министерства здравоохранения Российской Федерации | Method for creating polyneoplasia with stimulation of tumor growth in conditions of primary immunodeficiency in experiment |
| RU2750127C1 (en) * | 2021-02-02 | 2021-06-22 | федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр онкологии» Министерства здравоохранения Российской Федерации | A method for modeling the primary multiple growth of malignant tumors with the suppression of one tumor by another in the conditions of primary immunodeficiency |
-
2008
- 2008-08-11 RU RU2008133088/14A patent/RU2388064C1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2388064C1 (en) | 2010-04-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2008133088A (en) | METHOD FOR REPRODUCING A MALIGNANT PROCESS IN AN EXPERIMENT | |
| EA202091219A1 (en) | CULTIVATION OF THE PLACENTA FOR THE PURPOSE OF EXOSOM | |
| MX2015011280A (en) | Ship1 modulators and methods related thereto. | |
| CN105076113A (en) | Immunological cell freeze-saving method | |
| CN103966164A (en) | Preparation method of hemizygote CAPRI cells | |
| SG11201804755VA (en) | Method for manufacturing tissue/organ by using blood cells | |
| CN105219713A (en) | For high proliferation power, the High Fragmentation power NK cell of tumour adoptive immunity | |
| EA201591233A1 (en) | COMPOSITION OF INJECTION DEPOSIT, INCLUDING OPTICALLY ACTIVE TOLVAPTAN, AND A METHOD FOR ITS OBTAINING | |
| CN102351631A (en) | Alpha-pinene extracted from pine needle, its extraction method and application for resisting tumor | |
| RU2010134371A (en) | METHODS FOR RIPPING OVARIAN FOLICULES IN VITRO | |
| RU2011125447A (en) | METHOD FOR PRODUCING LUNG TUMORS IN EXPERIMENT | |
| RU2007120787A (en) | METHOD OF SKIN PLASTIC | |
| MD4296B1 (en) | Preparation from Tenebrio molitor larvae with antioxidant activity, process for its preparation and pharmaceutical product on its base | |
| RU2011105045A (en) | METHOD FOR COMBINED PATHOGENETICALLY-ORIENTED TREATMENT OF THE WET FORM OF AGE-RELATED MACULAR DETERMINATION OF THE RETAILS WITH THE APPLICATION OF CELL TRANSPLANTATION | |
| Jaiswal et al. | Horn cancer-A clinical insight into its diagnosis and management in 10 cattle | |
| Liu et al. | Study of Anti-Tumor Effect of NK Cells on Oral Tongue Squamous Cell Carcinoma | |
| US11160854B2 (en) | Immunostimulatory preparation exhibiting antitumor activity | |
| Alebiosu | HIV vaccine-How close are we? | |
| CN105524879A (en) | Method for extracting immune cells from bone marrow | |
| KumarSah et al. | Stem cells: Time for regenerative medicine | |
| Jiang et al. | Effects of chimerism on the mice heart transplanted survival with the bone marrow infusion | |
| Teryushkova et al. | TREATMENT OF RADIATION-INDUCED COLOVAGINAL FISTULA WITH AUTOLOGOUS FAT GRAFTING | |
| UA128145U (en) | A COMPLEX METHOD OF DETECTION OF NEUROPEPTIDES IN RAT BRAIN NEURES IN AN IMMUNOGISTOCHEMICAL RESEARCH | |
| RU2011132121A (en) | METHOD FOR STIMULATING NERVE REGENERATION | |
| EA201400039A1 (en) | METHOD OF CELLULAR TREATMENT OF EXPERIMENTAL CHRONIC ORCHOEPIDIDIMITIS |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20100812 |