RU2007111859A - Устройства и способы доставки лекарственных средств - Google Patents

Устройства и способы доставки лекарственных средств Download PDF

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Publication number
RU2007111859A
RU2007111859A RU2007111859/14A RU2007111859A RU2007111859A RU 2007111859 A RU2007111859 A RU 2007111859A RU 2007111859/14 A RU2007111859/14 A RU 2007111859/14A RU 2007111859 A RU2007111859 A RU 2007111859A RU 2007111859 A RU2007111859 A RU 2007111859A
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Prior art keywords
pump
remote controller
insulin
drug
delivering
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RU2007111859/14A
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English (en)
Inventor
Дэвид ХОЛ (US)
Дэвид ХОЛ
Йен ШИПВЕЙ (US)
Йен ШИПВЕЙ
Стивен ГЕТЦ (US)
Стивен ГЕТЦ
Ульрих КРАФТ (DE)
Ульрих КРАФТ
Манфред ЭБНЕР (DE)
Манфред ЭБНЕР
Торстен НИСС (DE)
Торстен НИСС
Йоахим БИНЦ (DE)
Йоахим БИНЦ
Штефан МУЛЛЕР-ПАТЛЕ (DE)
Штефан МУЛЛЕР-ПАТЛЕ
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Лайфскен, Инк. (Us)
Лайфскен, Инк.
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Publication of RU2007111859A publication Critical patent/RU2007111859A/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3569—Range sublocal, e.g. between console and disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/01—Remote controllers for specific apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/201—Glucose concentration

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Primary Health Care (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Business, Economics & Management (AREA)
  • General Business, Economics & Management (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (20)

1. Способ доставки болюса инсулина с использованием дистанционного регулятора, включающий стадии:
А) установления линии связи между дистанционным регулятором и инфузионным насосом, который содержит инсулин;
В) получение насосом значения болюсного объема от дистанционного регулятора, причем значение болюсного объема указывает общее количество инсулина, подлежащего подаче;
С) доставки заданной порции общего количества инсулина из насоса и
D) доставки дополнительной заданной порции общего количества инсулина из насоса на основании информации, включающей прием команды продолжения от дистанционного регулятора.
2. Способ по п.1, дополнительно включающий, по меньшей мере, одно повторение стадии D до тех пор, пока не будет доставлено общее количество инсулина.
3. Способ по п.1, где линия связи включает беспроводной сигнал, передаваемый между дистанционным регулятором и инфузионным насосом.
4. Способ по п.1, где дистанционный регулятор и инфузионный насос сообщаются посредством единственного в своем роде идентификационного кода.
5. Способ по п.1, дополнительно включающий получение дистанционным регулятором значения болюсного объема.
6. Способ по п.1, где дистанционный регулятор включает измеритель содержания глюкозы в крови.
7. Способ по п.1, дополнительно включающий непрерывную передачу сигнала, включающего команду к продолжению, причем сигнал передается от дистанционного регулятора к насосу.
8. Способ доставки болюса инсулина с использованием дистанционного регулятора, включающий стадии:
установления линии связи между дистанционным регулятором и инфузионным насосом, который содержит инсулин;
получения насосом значения болюсного объема от дистанционного регулятора, причем величина болюса указывает общее количество инсулина, подлежащего доставке;
доставки заданной порции общего количества инсулина из насоса и
запуска сигнала тревоги, если сигнал, включающий команду к продолжению, не получен насосом в пределах заданного периода времени.
9. Способ по п.8, где заданный период времени составляет от 1 до 60 с.
10. Способ по п.8, дополнительно включающий прекращение доставки инсулина из насоса на основании сигнала тревоги.
11. Способ по п.10, дополнительно включающий ожидание в течение второго заданного периода времени перед окончанием доставки инсулина из насоса.
12. Способ доставки болюса лекарственного средства с использованием дистанционного регулятора, включающий стадии:
установления линии связи между дистанционным регулятором и инфузионным насосом, который содержит лекарственное средство;
получения насосом значения болюсного объема от дистанционного регулятора, причем значение болюсного объема указывает общее количество лекарственного средства, подлежащего доставке;
доставки заданной порции общего количества лекарственного средства из насоса и
прекращения доставки лекарственного средства из насоса, если сигнал, включающий команду к продолжению, не принят насосом в пределах заданного периода времени.
13. Способ по п.12, где лекарственное средство включает инсулин.
14. Способ по п.12, где линия связи включает беспроводной сигнал, передаваемый между дистанционным регулятором и инфузионным насосом.
15. Способ по п.12, дополнительно включающий запуск сигнала тревоги в ответ на прекращение доставки лекарственного средства.
16. Способ доставки заданного количества болюса лекарственного средства в виде болюса, включающий стадии:
ввода значения заданного количества лекарственного средства в дистанционный регулятор;
беспроводной передачи информации, включающей заданное количество лекарственного средства, от дистанционного регулятора к насосу;
доставки заданной первой порции количества лекарственного средства из насоса и
доставки дополнительной заданной порции количества лекарственного средства из насоса в ответ на прием беспроводного сигнала от дистанционного регулятора, причем беспроводной сигнал включает инструкции продолжать доставку.
17. Способ по п.16, дополнительно включающий доставку всего количества лекарственного средства.
18. Способ по п.16, дополнительно включающий непрерывную подачу сигнала, включающего инструкции к продолжению доставки, причем сигнал передается от дистанционного регулятора к насосу.
19. Способ по п.16, дополнительно включающий получение дистанционным регулятором информации, включающей статус насоса.
20. Способ по п.16, где лекарственное средство включает инсулин.
RU2007111859/14A 2006-03-31 2007-03-30 Устройства и способы доставки лекарственных средств RU2007111859A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/394,812 2006-03-31
US11/394,812 US20070233051A1 (en) 2006-03-31 2006-03-31 Drug delivery systems and methods

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RU2007111859A true RU2007111859A (ru) 2008-10-10

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US (1) US20070233051A1 (ru)
EP (1) EP1839694A1 (ru)
JP (1) JP2007307359A (ru)
CN (1) CN101112630B (ru)
BR (1) BRPI0704538A (ru)
CA (1) CA2582912A1 (ru)
RU (1) RU2007111859A (ru)

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CN101112630A (zh) 2008-01-30
EP1839694A1 (en) 2007-10-03
BRPI0704538A (pt) 2008-05-13
CA2582912A1 (en) 2007-09-30
JP2007307359A (ja) 2007-11-29
CN101112630B (zh) 2012-10-10
US20070233051A1 (en) 2007-10-04

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