RU2007104650A - BACTERIA OF THE ENTERODACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE OPERON YhcA-E, PRODUCER OF L-AMINO ACID AND METHOD FOR PRODUCING L-AMINO ACID, WAS WEARED - Google Patents

BACTERIA OF THE ENTERODACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE OPERON YhcA-E, PRODUCER OF L-AMINO ACID AND METHOD FOR PRODUCING L-AMINO ACID, WAS WEARED Download PDF

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Publication number
RU2007104650A
RU2007104650A RU2007104650/13A RU2007104650A RU2007104650A RU 2007104650 A RU2007104650 A RU 2007104650A RU 2007104650/13 A RU2007104650/13 A RU 2007104650/13A RU 2007104650 A RU2007104650 A RU 2007104650A RU 2007104650 A RU2007104650 A RU 2007104650A
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RU
Russia
Prior art keywords
amino acid
aromatic
bacterium
group
yhca
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RU2007104650/13A
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Russian (ru)
Inventor
Дмитрий Владимирович Филиппов (RU)
Дмитрий Владимирович Филиппов
Эльвира Борисовна Ворошилова (RU)
Эльвира Борисовна Ворошилова
тинер Михаил Маркович Гус (RU)
Михаил Маркович Гусятинер
Original Assignee
Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU)
Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ)
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Application filed by Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU), Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) filed Critical Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU)
Priority to RU2007104650/13A priority Critical patent/RU2007104650A/en
Publication of RU2007104650A publication Critical patent/RU2007104650A/en

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Claims (11)

1. Бактерия-продуцент L-аминокислоты, принадлежащая к семейству Enterobacteriaceae, модифицированная таким образом, что экспрессия оперона yhcA-E в указанной бактерии ослаблена.1. L-amino acid producing bacterium belonging to the Enterobacteriaceae family, modified so that expression of the yhcA-E operon in said bacterium is weakened. 2. Бактерия по п.1, отличающаяся тем, что экспрессия указанного оперона yhcA-E ослаблена за счет инактивации указанного оперона yhcA-Е.2. The bacterium according to claim 1, characterized in that the expression of the specified yhcA-E operon is weakened due to inactivation of the specified yhcA-E operon. 3. Бактерия по п.1, отличающаяся тем, что указанная бактерия принадлежит к роду Escherichia.3. The bacterium according to claim 1, characterized in that said bacterium belongs to the genus Escherichia. 4. Бактерия по п.1, отличающаяся тем, что указанная бактерия принадлежит к роду Pantoea.4. The bacterium according to claim 1, characterized in that said bacterium belongs to the genus Pantoea. 5. Бактерия-продуцент L-аминокислоты по любому из пп.1-4, отличающаяся тем, что указанная L-аминокислота выбрана из группы, состоящей из ароматической L-аминокислоты и неароматической L-аминокислоты.5. The bacterium producing L-amino acids according to any one of claims 1 to 4, characterized in that said L-amino acid is selected from the group consisting of aromatic L-amino acids and non-aromatic L-amino acids. 6. Бактерия-продуцент L-аминокислоты по п.5, отличающаяся тем, что указанная ароматическая L-аминокислота выбрана из группы, состоящей из L-фенилаланина, L-тирозина и L-триптофана.6. The L-amino acid producing bacterium according to claim 5, characterized in that said aromatic L-amino acid is selected from the group consisting of L-phenylalanine, L-tyrosine and L-tryptophan. 7. Бактерия-продуцент L-аминокислоты по п.5, отличающаяся тем, что указанная неароматическая L-аминокислота выбрана из группы, состоящей из L-треонина, L-лизина, L-цистеина, L-метионина, L-лейцина, L-изолейцина, L-валина, L-гистидина, L-глицина, L-серина, L-аланина, L-аспарагина, L-аспартата, L-глутамина, L-глутаминовой кислоты, L-пролина и L-аргинина.7. The L-amino acid producing bacterium according to claim 5, characterized in that said non-aromatic L-amino acid is selected from the group consisting of L-threonine, L-lysine, L-cysteine, L-methionine, L-leucine, L- isoleucine, L-valine, L-histidine, L-glycine, L-serine, L-alanine, L-asparagine, L-aspartate, L-glutamine, L-glutamic acid, L-proline and L-arginine. 8. Способ получения L-аминокислоты, включающий8. The method of obtaining L-amino acids, including выращивание бактерии по любому из пп.1-7 в питательной среде, вызывающее продукцию и накопление указанной L-аминокислоты в культуральной жидкости; иgrowing bacteria according to any one of claims 1 to 7 in a nutrient medium, causing production and accumulation of the specified L-amino acids in the culture fluid; and выделение указанной L-аминокислоты из культуральной жидкости.the allocation of the specified L-amino acids from the culture fluid. 9. Способ по п.8, отличающийся тем, что указанная L-аминокислота выбрана из группы, состоящей из ароматической L-аминокислоты и неароматической L-аминокислоты.9. The method of claim 8, wherein said L-amino acid is selected from the group consisting of an aromatic L-amino acid and a non-aromatic L-amino acid. 10. Способ по п.9, отличающийся тем, что указанная ароматическая L-аминокислота выбрана из группы, состоящей из L-фенилаланина, L-тирозина и L-триптофана.10. The method according to claim 9, characterized in that said aromatic L-amino acid is selected from the group consisting of L-phenylalanine, L-tyrosine and L-tryptophan. 11. Способ по п.9, отличающийся тем, что указанная неароматическая L-аминокислота выбрана из группы, состоящей из L-треонина, L-лизина, L-цистеина, L-метионина, L-лейцина, L-изолейцина, L-валина, L-гистидина, L-глицина, L-серина, L-аланина, L-аспарагина, L-аспартата, L-глутамина, L-глутаминовой кислоты, L-пролина и L-аргинина.11. The method according to claim 9, characterized in that said non-aromatic L-amino acid is selected from the group consisting of L-threonine, L-lysine, L-cysteine, L-methionine, L-leucine, L-isoleucine, L-valine , L-histidine, L-glycine, L-serine, L-alanine, L-asparagine, L-aspartate, L-glutamine, L-glutamic acid, L-proline and L-arginine.
RU2007104650/13A 2007-02-07 2007-02-07 BACTERIA OF THE ENTERODACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE OPERON YhcA-E, PRODUCER OF L-AMINO ACID AND METHOD FOR PRODUCING L-AMINO ACID, WAS WEARED RU2007104650A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2007104650/13A RU2007104650A (en) 2007-02-07 2007-02-07 BACTERIA OF THE ENTERODACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE OPERON YhcA-E, PRODUCER OF L-AMINO ACID AND METHOD FOR PRODUCING L-AMINO ACID, WAS WEARED

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RU2007104650/13A RU2007104650A (en) 2007-02-07 2007-02-07 BACTERIA OF THE ENTERODACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE OPERON YhcA-E, PRODUCER OF L-AMINO ACID AND METHOD FOR PRODUCING L-AMINO ACID, WAS WEARED

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2482188C2 (en) * 2010-07-21 2013-05-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) METHOD FOR PREPARING L-ARGININE WITH USE OF BACTERIA OF GENUS Escherichia WHEREIN astCADBE OPERON IS INACTIVATED

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2482188C2 (en) * 2010-07-21 2013-05-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) METHOD FOR PREPARING L-ARGININE WITH USE OF BACTERIA OF GENUS Escherichia WHEREIN astCADBE OPERON IS INACTIVATED

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