RU2006100896A - METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE yfeH GENE IS INACTIVATED - Google Patents

METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE yfeH GENE IS INACTIVATED Download PDF

Info

Publication number
RU2006100896A
RU2006100896A RU2006100896/13A RU2006100896A RU2006100896A RU 2006100896 A RU2006100896 A RU 2006100896A RU 2006100896/13 A RU2006100896/13 A RU 2006100896/13A RU 2006100896 A RU2006100896 A RU 2006100896A RU 2006100896 A RU2006100896 A RU 2006100896A
Authority
RU
Russia
Prior art keywords
amino acids
aromatic
amino acid
bacterium
group
Prior art date
Application number
RU2006100896/13A
Other languages
Russian (ru)
Other versions
RU2337959C2 (en
Inventor
Константин В чеславович Рыбак (RU)
Константин Вячеславович Рыбак
Екатерина Александровна Сливинска (RU)
Екатерина Александровна Сливинская
Эльвира Борисовна Ворошилова (RU)
Эльвира Борисовна Ворошилова
Юрий Иванович Козлов (RU)
Юрий Иванович Козлов
Original Assignee
Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU)
Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU), Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) filed Critical Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU)
Priority to RU2006100896/13A priority Critical patent/RU2337959C2/en
Priority to PCT/JP2007/050873 priority patent/WO2007083789A1/en
Publication of RU2006100896A publication Critical patent/RU2006100896A/en
Application granted granted Critical
Publication of RU2337959C2 publication Critical patent/RU2337959C2/en

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Claims (11)

1. Бактерия-продуцент L-аминокислоты, принадлежащая к семейству Enterobacteriaceae, модифицированная таким образом, что в указанной бактерии экспрессия гена yfeH ослаблена.1. L-amino acid producing bacterium belonging to the Enterobacteriaceae family, modified so that the expression of the yfeH gene in this bacterium is weakened. 2. Бактерия по п.1, отличающаяся тем, что указанная экспрессия гена yfeH ослаблена путем инактивации гена yfeH.2. The bacterium according to claim 1, characterized in that said expression of the yfeH gene is attenuated by inactivation of the yfeH gene. 3. Бактерия по п.1, отличающаяся тем, что указанная бактерия принадлежит к роду Escherichia.3. The bacterium according to claim 1, characterized in that said bacterium belongs to the genus Escherichia. 4. Бактерия по п.1, отличающаяся тем, что указанная бактерия принадлежит к роду Pantoea.4. The bacterium according to claim 1, characterized in that said bacterium belongs to the genus Pantoea. 5. Бактерия-продуцент L-аминокислоты по любому из пп.1-4, отличающаяся тем, что указанная L-аминокислота выбрана из группы, состоящей из ароматических L-аминокислот и неароматических L-аминокислот.5. A bacterium producing L-amino acids according to any one of claims 1 to 4, characterized in that said L-amino acid is selected from the group consisting of aromatic L-amino acids and non-aromatic L-amino acids. 6. Бактерия-продуцент L-аминокислоты по п.5, отличающаяся тем, что указанная ароматическая L-аминокислота выбрана из группы, состоящей из L-фенилаланина, L-тирозина и L-триптофана.6. The L-amino acid producing bacterium according to claim 5, characterized in that said aromatic L-amino acid is selected from the group consisting of L-phenylalanine, L-tyrosine and L-tryptophan. 7. Бактерия-продуцент L-аминокислоты по п.5, отличающаяся тем, что указанная неароматическая L-аминокислота выбрана из группы, состоящей из L-треонина, L-лизина, L-цистеина, L-метионина, L-лейцина, L-изолейцина, L-валина, L-гистидина, L-глицина, L-серина, L-аланина, L-аспарагина, L-аспарагиновой кислоты, L-глутамина, L-глутаминовой кислоты, L-пролина и L-аргинина.7. The L-amino acid producing bacterium according to claim 5, characterized in that said non-aromatic L-amino acid is selected from the group consisting of L-threonine, L-lysine, L-cysteine, L-methionine, L-leucine, L- isoleucine, L-valine, L-histidine, L-glycine, L-serine, L-alanine, L-asparagine, L-aspartic acid, L-glutamine, L-glutamic acid, L-proline and L-arginine. 8. Способ получения L-аминокислоты, включающий8. The method of obtaining L-amino acids, including выращивание бактерии по любому из пп.1-7 в питательной среде, иgrowing bacteria according to any one of claims 1 to 7 in a nutrient medium, and выделение указанной L-аминокислоты из культуральной жидкости.the allocation of the specified L-amino acids from the culture fluid. 9. Способ по п.8, отличающийся тем, что указанная L-аминокислота выбрана из группы, состоящей из ароматических L-аминокислот и неароматических L-аминокислот.9. The method of claim 8, wherein said L-amino acid is selected from the group consisting of aromatic L-amino acids and non-aromatic L-amino acids. 10. Способ по п.9, отличающийся тем, что указанная ароматическая L-аминокислота выбрана из группы, состоящей из L-фенилаланина, L-тирозина и L-триптофана.10. The method according to claim 9, characterized in that said aromatic L-amino acid is selected from the group consisting of L-phenylalanine, L-tyrosine and L-tryptophan. 11. Способ по п.9, отличающийся тем, что указанная неароматическая L-аминокислота выбрана из группы, состоящей из L-треонина, L-лизина, L-цистеина, L-метионина, L-лейцина, L-изолейцина, L-валина, L-гистидина, L-глицина, L-серина, L-аланина, L-аспарагина, L-аспарагиновой кислоты, L-глутамина, L-глутаминовой кислоты, L-пролина и L-аргинина.11. The method according to claim 9, characterized in that said non-aromatic L-amino acid is selected from the group consisting of L-threonine, L-lysine, L-cysteine, L-methionine, L-leucine, L-isoleucine, L-valine , L-histidine, L-glycine, L-serine, L-alanine, L-asparagine, L-aspartic acid, L-glutamine, L-glutamic acid, L-proline and L-arginine.
RU2006100896/13A 2006-01-17 2006-01-17 METHOD OF OBTAINING L-THREONINE USING BACTERIUM, BELONGING TO GENUS Escherichia, IN WHICH GENE yfeH IS INACTIVATED RU2337959C2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
RU2006100896/13A RU2337959C2 (en) 2006-01-17 2006-01-17 METHOD OF OBTAINING L-THREONINE USING BACTERIUM, BELONGING TO GENUS Escherichia, IN WHICH GENE yfeH IS INACTIVATED
PCT/JP2007/050873 WO2007083789A1 (en) 2006-01-17 2007-01-16 A method for producing an l-amino acid using a bacterium of enterobacteriaceae family with attenuated expression of the yfeh gene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2006100896/13A RU2337959C2 (en) 2006-01-17 2006-01-17 METHOD OF OBTAINING L-THREONINE USING BACTERIUM, BELONGING TO GENUS Escherichia, IN WHICH GENE yfeH IS INACTIVATED

Publications (2)

Publication Number Publication Date
RU2006100896A true RU2006100896A (en) 2007-07-27
RU2337959C2 RU2337959C2 (en) 2008-11-10

Family

ID=38431400

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006100896/13A RU2337959C2 (en) 2006-01-17 2006-01-17 METHOD OF OBTAINING L-THREONINE USING BACTERIUM, BELONGING TO GENUS Escherichia, IN WHICH GENE yfeH IS INACTIVATED

Country Status (1)

Country Link
RU (1) RU2337959C2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2010101135A (en) 2010-01-15 2011-07-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) (RU) BACTERIA OF THE ENTEROBACTERIACEAE FAMILY - PRODUCER OF L-ASAPPARATE OR METABOLITES, L-ASPARATE DERIVATIVES, AND METHOD OF PRODUCING L-ASAPPARATE OR METABOLITES, PRODUCED L-ASAPPARATE
RU2472853C2 (en) * 2011-01-14 2013-01-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Enterobacteriaceae BACTERIA FAMILY - PRODUCER OF L-ASPARTIC ACID OR METABOLITES, L-ASPARTIC ACID DERIVATIVES, AND METHOD OF PRODUCING L-ASPARTIC ACID OR METABOLITES, L-ASPARTIC ACID DERIVATIVES

Also Published As

Publication number Publication date
RU2337959C2 (en) 2008-11-10

Similar Documents

Publication Publication Date Title
RU2004137198A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE Enterobacteriaceae Family In Which The yafA Gene Is Inactivated
RU2006143864A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE EXPRESSION OF GENES cynT, cynS, cynX, OR cynR, OR THEIR COMBINATION IS DECREASED
RU2006123752A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE FAMILY Enterobacteriaceae, IN WHICH EXPRESSION OF THE OPERON rspAB IS DECREASED
RU2005101110A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE Glycogen biosynthesis pathway has been destroyed
RU2006100896A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE yfeH GENE IS INACTIVATED
RU2007104648A (en) METHOD FOR PRODUCING L-AMINO ACID USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE EXPRESSION OF THE tolC GENE IS DECREASED
RU2006112259A (en) METHOD FOR PRODUCING L-AMINO ACID USING THE ENTEROBACTERIACEAE FAMILY BACTERIA MODIFIED IN SUCH A PERFORMANCE THAT THE KERLI TYPE FORMATION IS DISCONNECTED IN IT
RU2006112625A (en) METHOD FOR PRODUCING L-AMINO ACID USING THE Enterobacteriaceae Bacteria in Which the Expression of the fhuA Gene Is Weakened
RU2006100895A (en) METHOD FOR PRODUCING L-AMINO ACID USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE lrhA GENE IS INACTIVATED
RU2007128314A (en) METHOD FOR PRODUCING L-AMINO ACID USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE yncD GENE IS DECREASED
RU2006118967A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE ENTEROBACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE RCSA GENE IS WEAKEN
RU2005106347A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE NAC GENE IS INACTIVATED
RU2005123423A (en) Bacteria of the Enterobacteriaceae family in which the pnp gene is inactivated, the producer of L-amino acids and the method for producing L-amino acids
RU2007106185A (en) BACTERIA OF THE FAMILY ENTEPOBACTERIACEAE, WHICH EXPRESSION OF THE OPERON YcbPONME (SSUEADCB) WAS WEARED, IS A PRODUCER OF L-AMINO ACID AND A METHOD FOR PRODUCING L-AMINO ACID
RU2007104650A (en) BACTERIA OF THE ENTERODACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE OPERON YhcA-E, PRODUCER OF L-AMINO ACID AND METHOD FOR PRODUCING L-AMINO ACID, WAS WEARED
RU2006112624A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE enterobacteriaceae FAMILY IN WHICH EXPRESSION OF THE SfmACDFH-fimZ CLUSTER OR fimZ GENE
RU2010129270A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY
RU2007106189A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE OPERON YcbQRSTUVF IS DECREASED
RU2006106310A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH GENE B2383 IS INACTIVATED
RU2007105212A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE ecpD GENE OR OPERON ecpD-htrE is weakened
RU2006101788A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE fdrA GENE IS INACTIVATED
RU2006102180A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE BISC GENE IS INACTIVATED
RU2006116167A (en) METHOD FOR PRODUCING L-AMINO ACID USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE EXPRESSION OF THE KEFB GENE IS DECREASED
RU2006112261A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE Enterobacteriaceae Family In Which Expression Of The ybdA Gene Is Weakened
RU2006104648A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE EXPRESSION OF THE PAS GENE IS DECREASED