RU2006124937A - METHOD FOR FORECASTING THE COURSE OF DIABETES TYPE 1 - Google Patents

METHOD FOR FORECASTING THE COURSE OF DIABETES TYPE 1 Download PDF

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RU2006124937A
RU2006124937A RU2006124937/14A RU2006124937A RU2006124937A RU 2006124937 A RU2006124937 A RU 2006124937A RU 2006124937/14 A RU2006124937/14 A RU 2006124937/14A RU 2006124937 A RU2006124937 A RU 2006124937A RU 2006124937 A RU2006124937 A RU 2006124937A
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RU
Russia
Prior art keywords
course
risk factors
prognostic
forecasting
predict
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RU2006124937/14A
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Russian (ru)
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RU2320272C1 (en
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Тать на Прокопьевна Бардымова (RU)
Татьяна Прокопьевна Бардымова
Иван Иванович Дедов (RU)
Иван Иванович Дедов
Любовь Ильинична Колесникова (RU)
Любовь Ильинична Колесникова
Светлана Васильевна Тюменцева (RU)
Светлана Васильевна Тюменцева
Вера Александровна Петрова (RU)
Вера Александровна Петрова
Исай Моисеевич Михалевич (RU)
Исай Моисеевич Михалевич
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Тать на Прокопьевна Бардымова (RU)
Татьяна Прокопьевна Бардымова
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Priority to RU2006124937/14A priority Critical patent/RU2320272C1/en
Publication of RU2006124937A publication Critical patent/RU2006124937A/en
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Publication of RU2320272C1 publication Critical patent/RU2320272C1/en

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  • Investigating Or Analysing Biological Materials (AREA)

Claims (1)

Способ прогнозирования течения сахарного диабета 1 типа, включающий клиническое обследование больного, определение биохимических показателей крови и установление прогностических факторов риска, отличающийся тем, что определяют прогностические факторы риска (ФР): возраст, уровень антиокислительной активности, содержание общих липидов, концентрацию диеновых конъюгатов, а прогностические значения факторов риска F1, F2, F3 и F4 определяют по формуламA method for predicting the course of type 1 diabetes mellitus, including a clinical examination of the patient, determination of blood biochemical parameters and establishment of prognostic risk factors, characterized in that prognostic risk factors (RF) are determined: age, antioxidant activity level, total lipid content, concentration of diene conjugates, and prognostic values of risk factors F1, F2, F3 and F4 are determined by the formulas F1=-21,84+1,33·а1+0,59·а2+0,14·а3-0,94·а4;F1 = -21.84 + 1.33 · a1 + 0.59 · a2 + 0.14 · a3-0.94 · a4; F2=-49,72+2,04·а1+1,64·а2+0,44·а3-1,19·а4;F2 = -49.72 + 2.04 · a1 + 1.64 · a2 + 0.44 · a3-1.19 · a4; F3=-8,06+0,75·а1+1,61·а2-0,22·а3-0,26·а4;F3 = -8.06 + 0.75 · a1 + 1.61 · a2-0.22 · a3-0.26 · a4; F4=-6,82+0,64·а1-0,85·а2+0,30·а3-0,37·а4,F4 = -6.82 + 0.64 · a1-0.85 · a2 + 0.30 · a3-0.37 · a4, соответственно respectively где а1, а2, а3, а4 - градации ФР:where a1, a2, a3, a4 are the gradations of the FR: a1 - количество полных лет;a1 is the number of full years; а2 - антиокислительная активность в у.ед.;A2 - antioxidant activity in unit; а3 - содержание общих липидов в г/л;a3 is the content of total lipids in g / l; а4 - концентрация диеновых конъюгатов в мкмоль/л;A4 is the concentration of diene conjugates in μmol / L; и при F1>F2, F3, F4 или F2>F1, F3, F4 - прогнозируют высокий риск раннего развития микрососудистых осложнений, а при F3>F1, F2, F4 или F4>F1, F3, F2 - прогнозируют развитие микрососудистых осложнений, соответствующих длительности заболевания.and for F1> F2, F3, F4 or F2> F1, F3, F4 - they predict a high risk of early development of microvascular complications, and for F3> F1, F2, F4 or F4> F1, F3, F2 - they predict the development of microvascular complications corresponding to the duration of the disease.
RU2006124937/14A 2006-07-11 2006-07-11 Method for predicting the flow of type i diabetes RU2320272C1 (en)

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RU2006124937A true RU2006124937A (en) 2008-01-20
RU2320272C1 RU2320272C1 (en) 2008-03-27

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2461356C1 (en) * 2011-03-29 2012-09-20 Государственное образовательное учреждение высшего профессионального образования Ижевская государственная медицинская академия Министерства здравоохранения и социального развития Российской Федерации Method for prediction of clinical course of diabetes mellitus
RU2491925C2 (en) * 2011-09-28 2013-09-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Ростовский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО РостГМУ Минздрава России) Method for prediction of clinical effectiveness of diabetic polyneuropathy in patients with type 2 diabetes mellitus and dyslipidemia
RU2557928C2 (en) * 2013-12-25 2015-07-27 Государственное бюджетное образовательное учреждение высшего профессионального образования Читинская государственная медицинская академия Министерства здравоохранения РФ Method for prediction of risk of early microvascular complications of type i diabetes mellitus in children

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