RU2000126276A - A MEDICINE FOR PREVENTION AND / OR TREATMENT OF BREAST CANCER CONTAINING A STEROID AROMATASE INHIBITOR - Google Patents

A MEDICINE FOR PREVENTION AND / OR TREATMENT OF BREAST CANCER CONTAINING A STEROID AROMATASE INHIBITOR

Info

Publication number
RU2000126276A
RU2000126276A RU2000126276/14A RU2000126276A RU2000126276A RU 2000126276 A RU2000126276 A RU 2000126276A RU 2000126276/14 A RU2000126276/14 A RU 2000126276/14A RU 2000126276 A RU2000126276 A RU 2000126276A RU 2000126276 A RU2000126276 A RU 2000126276A
Authority
RU
Russia
Prior art keywords
drug
use according
prevention
treatment
breast cancer
Prior art date
Application number
RU2000126276/14A
Other languages
Russian (ru)
Other versions
RU2225206C2 (en
Inventor
Альфред ШМИДТ
Хайнрих ВИЛАНД
Original Assignee
С.В.Патентфервертунгс Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP98104949A external-priority patent/EP0943333A1/en
Application filed by С.В.Патентфервертунгс Гмбх filed Critical С.В.Патентфервертунгс Гмбх
Publication of RU2000126276A publication Critical patent/RU2000126276A/en
Application granted granted Critical
Publication of RU2225206C2 publication Critical patent/RU2225206C2/en

Links

Claims (7)

1. Применение стероидного ингибитора ароматазы для получения готовой формы лекарственного препарата для локального местного применения для профилактики и/или лечения рака молочной железы, при этом препарат свободен от антигестагенов.1. The use of a steroidal aromatase inhibitor for the preparation of a topical drug for local topical use for the prevention and / or treatment of breast cancer, while the drug is free of antigestagens. 2. Применение по п. 1, отличающееся тем, что лекарственный препарат содержит форместан (4-гидроксиандрост-4-ен-3,17-дион) и/или фармакологически приемлемое производное форместана. 2. The use according to claim 1, characterized in that the drug contains formestane (4-hydroxyandrost-4-en-3,17-dione) and / or a pharmacologically acceptable derivative of formestane. 3. Применение по п. 2, отличающееся тем, что лекарственный препарат содержит 4-0-ацетиландрост-4-ен-3,17-дион. 3. The use according to claim 2, characterized in that the drug contains 4-0-acetylandrost-4-en-3,17-dione. 4. Применение по одному из пп. 1-3, отличающееся тем, что лекарственный препарат содержит дополнительно вещество для усиления проницаемости кожи. 4. The use according to one of paragraphs. 1-3, characterized in that the drug additionally contains a substance to enhance the permeability of the skin. 5. Применение по п. 4, отличающееся тем, что лекарственный препарат содержит ДМСО. 5. The use according to claim 4, characterized in that the drug contains DMSO. 6. Применение по одному из пп. 1-5, отличающееся тем, что лекарственный препарат приготовлен в виде мази, крема, геля, эмульсии или лосьона. 6. The use according to one of paragraphs. 1-5, characterized in that the drug is prepared in the form of an ointment, cream, gel, emulsion or lotion. 7. Применение по п. 6, отличающееся тем, что содержание активного вещества составляет 0,0001-20 вес. %, предпочтительно 0,6-10 вес. %, наиболее предпочтительно 1-5 вес. %. 7. The use according to claim 6, characterized in that the content of the active substance is 0.0001-20 weight. %, preferably 0.6-10 weight. %, most preferably 1-5 weight. %
RU2000126276/15A 1998-03-18 1999-03-03 Medicinal preparation containing aromatase steroid inhibitor for prophylaxis and/or treatment of mammary cancer RU2225206C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98104949.7 1998-03-18
EP98104949A EP0943333A1 (en) 1998-03-18 1998-03-18 Medicament for the prevention and/or treatment of breast cancer comprising an inhibitor of estrogen synthesis

Publications (2)

Publication Number Publication Date
RU2000126276A true RU2000126276A (en) 2002-08-27
RU2225206C2 RU2225206C2 (en) 2004-03-10

Family

ID=8231611

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2000126276/15A RU2225206C2 (en) 1998-03-18 1999-03-03 Medicinal preparation containing aromatase steroid inhibitor for prophylaxis and/or treatment of mammary cancer

Country Status (19)

Country Link
EP (2) EP0943333A1 (en)
JP (1) JP4920822B2 (en)
KR (1) KR100778803B1 (en)
CN (1) CN1168448C (en)
AT (1) ATE230995T1 (en)
AU (1) AU751040B2 (en)
BR (1) BR9908885A (en)
CA (1) CA2324077C (en)
CZ (1) CZ292643B6 (en)
DE (1) DE59904042D1 (en)
DK (1) DK1063998T3 (en)
ES (1) ES2190201T3 (en)
HU (1) HU226105B1 (en)
ID (1) ID26965A (en)
IL (1) IL138292A (en)
PL (1) PL343100A1 (en)
RU (1) RU2225206C2 (en)
SK (1) SK285349B6 (en)
WO (1) WO1999047143A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10042411A1 (en) * 2000-08-30 2002-03-28 Lohmann Therapie Syst Lts Transdermal therapeutic system for the delivery of exemestane
DE10054294A1 (en) * 2000-11-02 2002-05-16 Heinrich Wieland Topical treatment for mastalgia
JP4524296B2 (en) * 2007-03-30 2010-08-11 生化学工業株式会社 Hair growth promoter
DE102007032468A1 (en) 2007-07-10 2009-01-15 Brätter, Christian, Dr. Transdermal therapeutic systems containing the active substance anastrozole
ES2694582T3 (en) * 2011-01-31 2018-12-21 Lucolas-M.D. Ltd. Combinations of aromatase inhibitors and antioxidants
RU2631483C2 (en) * 2011-01-31 2017-09-22 Луколас-М.Д. Лтд Cosmetic application
US11850451B2 (en) 2011-01-31 2023-12-26 Lucolas-M.D. Ltd. Cosmetic compositions and methods for improving skin conditions
EP3666276A1 (en) * 2018-12-14 2020-06-17 dcic Biopharmaceutical Limited Medication against estrogen-receptor beta (erbeta) positive breast tumor

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235893A (en) * 1978-05-08 1980-11-25 Brodie Angela M Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis
DE3322285A1 (en) * 1983-06-18 1984-12-20 Schering AG, 1000 Berlin und 4709 Bergkamen 1-ALKYL-ANDROSTA-1,4-DIEN-3,17-DIONE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
FR2558373B1 (en) * 1984-01-20 1987-07-03 Mauvais Jarvis Pierre ANTI-ESTROGEN MEDICINAL PRODUCT BASED ON 4-HYDROXYTAMOXIFENE FOR PERCUTANEOUS ADMINISTRATION
JPS6345294A (en) * 1986-04-07 1988-02-26 Shionogi & Co Ltd Aromatase-inhibiting steroid derivative
EP0310542B1 (en) * 1987-10-01 1994-06-08 Schering Aktiengesellschaft Antigestagenic and antioestrogenic compounds for the treatment of hormone-dependent tumours
FR2656310B1 (en) * 1989-12-22 1992-05-07 Roussel Uclaf NEW STEROUID PRODUCTS COMPRISING IN POSITION 10, A SUBSTITUTED THIOETHYL RADICAL, THEIR PREPARATION METHOD AND THE INTERMEDIATES THEREOF, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
DE4039559A1 (en) * 1990-12-07 1992-06-11 Schering Ag FUNCTIONALIZED VINYLAZOLES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THIS VINYLAZOLES AND THE USE THEREOF FOR THE PRODUCTION OF MEDICINAL PRODUCTS
GB9212833D0 (en) * 1992-06-17 1992-07-29 Glaxo Group Ltd Chemical compounds
EP0689536B1 (en) * 1993-03-16 2001-05-23 Pfizer Inc. Naphthalene derivatives
JPH07215992A (en) * 1993-12-07 1995-08-15 Teikoku Hormone Mfg Co Ltd 6-or 7-substituted androsra-1,4-diene derivative
US6020327A (en) * 1994-09-14 2000-02-01 The Central Sheffield University Hospitals Nhs Trust Control of hair growth
US5780050A (en) * 1995-07-20 1998-07-14 Theratech, Inc. Drug delivery compositions for improved stability of steroids
EP0907351B2 (en) * 1996-03-29 2012-04-18 Keyvest GmbH Cosmetic or cosmetic preparation for smoothing and tightening the skin in the case of subcutaneous fatty tissue problems, particularly cellulite
CA2632790A1 (en) * 1996-07-22 1998-01-29 Renovo Limited Use of sex steroid function modulators to treat wounds and fibrotic disorders

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