RU1821193C - Method of treating arthrosis deformans - Google Patents

Abstract

The invention relates to medicine, namely to arthrology, and can be used in the treatment of patients with deforming arthrosis due to an increase in fluoride content in the body. The method is carried out by conducting 2 courses of electrophoresis of a 5% solution of manganese sulfate with an interval between courses of 20-40 days and after the second course of reflexology, including superficial acupuncture of the paravertebral areas and the use of braking needles on corporal and auricular acupuncture points.

Description

The invention relates to medicine, namely to therapy, and can be used in the treatment of patients with Deforming arthrosis.

The purpose of the invention is the treatment of arthrosis due to an increase in fluoride content in the body.

a The goal is achieved by saturating the patient’s body with manganese introduced by electrophoresis in a known manner with a course repeated after a period of time equal to the biological half-life (TB) for manganese, the course is repeated after 20-40 days, no less than after the second course of electrophoresis pro. They carry out acupuncture reflexotherapy at points that regulate mineral metabolism.

The method is carried out as follows .4,

Groups of patients are formed who are permanently living in the area endemic for fyodorosis, taking into account age, gender and occupational signs in which endemic arthrosis is diagnosed by

clinical, radiographic and biochemical parameters. A distinctive feature of arthrosis in the area endemic for fluorosis is its widespread nature. The simultaneous damage to large and small joints of the skeleton suggests the general nature of the physiotherapeutic effect, aimed both at eliminating the excess deposited fluorine and at correcting the metabolism in the bone and connective tissues with restoring the functions of the affected joints. Physiotherapy is carried out by electrophoresis of a 5% solution of manganese sulfate according to the general procedure.

The anode, from which two-charge manganese cations with an area of 300 cm are introduced, is placed in the interscapular region, and the cathode, a bifurcated electrode with a total area of 300 cm2 (150 cm each), is placed on the calf muscle area. The procedure is carried out, for example, on a Potok-1 apparatus with a current strength of up to 10 mA. which is set individually perceptibly (L

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no tingling sensations, the duration of the procedure is 10-20 minutes, for the course of treatment 10-15 sessions. The second course of electrophoresis of manganese ions is carried out similarly to the first one after a period of time equal in magnitude to the biological half-life (Te) of manganese from the body as a whole, i.e., after 20-40 days. Those are determined using the following equation:

Tb

In 2 0.693

----- - --- L ----,

LL

where Te is the biological half-life of the element (days) is the time during which the content of the element in the organ or in the body as a whole is halved;

I am a constant derivation, determined experimentally.

This repeated electrophoresis of manganese ions in a chemically active state allows the body to be saturated as much as possible without any side effects and partially normalize mineral metabolism. The choice of manganese as a biocurrent is due to its participation in many enzyme systems. It is a component of pyruvate carboxylase and arginase, activates peptidases, dehydrogenases, isocitric and block acids, as well as pyruvic acid decarboxylase, and is necessary for the synthesis of cartilage glycosaminoglycans. The effect of the Margay on bone tissue is probably due to its activating effect on alkaline phosphatase and the synthesis of acidic glycosaminoglycans in the bone matrix, where about 80% of the absorbed manganese is deposited. Manganese and fluorine have antagonistic properties with respect to many enzyme systems and, in particular, to calcium metabolism.

Fluorides are increasingly used in the treatment of bone diseases, since under certain conditions they stimulate bone formation. At the same time, osteogenesis proceeds with the formation of an excess of extracellular matrix, poorly amenable to mineralization and functional restructuring. The effect of fluorine on bone tissue is manifold and, when the dose is changed, the opposite result can be obtained. Endemic fluorosis with prolonged exposure to low fluorine concentrations causes osteosclerosis, and at high doses, osteomalacia.

After the second course of electrophoresis with manganese sulfate, an acupuncture reflexology course is carried out according to the scheme:

1 session: KIT; II TMV: GU (2); Gln (2) AIT: shen-men (2)

2 session: KIT; II TMV: Hughes (2); T and: T2o: / 62 (2) AIT: sympathetic (2) 3 session: CIT; II TMV: MSb (2); H2; Eze (2) RPe (2) AIT: endocrine glands (2)

4 session: KIT; II TMV: TRe (2); TRis (2); Veo (2); Rad AIT: ZERO (2) 5 session: CIT; IVTM: RB (2); 1h; P7 (2) AIT: kidney (2)

6 session: points of 1 session

7 session: point 2 session

8 session: points 3 sessions

5 9 session: points of 4 sessions 10 session: points of 5 sessions Before acupuncture, patients undergo surface acupuncture (PIT) with a roller-roller para0 vertebral from Co-Ci to Ls-Si for 5-7 minutes, for a course of 10 procedures. (KIT - corporal acupuncture, AIT - auriculopuncture, IRT - acupuncture, II VTM - the second inhibitory method),

5 Example 1. Sick A., 38 years old. Complained of persistent pain in the knee, elbow and interphalangeal joints of the hands, aggravated by evening, obstructed movement when descending the stairs,

0 deformation of the knee joints, pain in the cervical and thoracic spine.

Sick about 12 years. I did not seek medical help. Over the past year and a half marks the deformation of the knee

5 joints, restriction of movement in them, especially when descending stairs. I applied for help 8 months ago, received indomethacin, analgin electrophoresis, and mud applications on the knee area

0 joints, no effect.

On examination, the patient's condition is satisfactory, there is an increase in the volume of the knee joints, some restriction of movement in them, as well as limited movement in the cervical spine and shoulder joints; Palpation of the paravertebral points Cs - Ce, DI - D4 painful. On the part of the lungs and heart, no pathological changes were detected. The geodynamic indicators are normal: the pulse is 68 beats per min., BP 120/70 mm Hg. Art. From the abdominal organs without features.

Laboratory data; general analysis

5. blood: Not - 150 g / l, 4.5 1012 / l, L-6.0 109 / l, p-2, C - 68, l - 24, m - 6, ESR - 5 mm / hour. General urine analysis: beats, weight. - 1018, no protein. L- 1 - 2 in the field of vision. Blood fibrinogen 2400 g / l. SRV (-) neg., Sample Malen (-) neg., Sialic acids - 180 units.

Biochemical parameters before treatment: serum calcium - 1.76 mmol / l, inorganic phosphorus - 0.74 mmol / l. the activity of alkaline phosphatase in serum is 70.1 U / l, fluorine in the urine is 2.24.

X-ray data: Ro-graphs of the knee, elbow, interphalangeal joints of the hands of the hands - arthrosis, Ru-graphs of the cervical spine - intervertebral osteochondrosis with primary lesions Cs - Sat, Ce - C, Oz - D4.

Diagnosis: primary deforming osteoarthrosis of large joints 1 tbsp., FNN Osteochondrosis of the cervical and thoracic spine. Twelve electrophoresis procedures were carried out for a 5% solution of manganese sulfate by the general method of displacement of deposited fluorine. After the course of treatment, he noted the disappearance of pain and better mobility in the knee joints, there remained moderate pain in the cervical spine. After 30 days, a second course of electrophoresis was completed from 12 procedures to saturate the body with manganese ions. She received 10 acupuncture reflexotherapy sessions to regulate mineral metabolism and 10 sessions of superficial IRT paravertebral. As a result of the treatment, significant improvements are noted; There are no complaints; performance has been restored. These clinical changes directly correlated with biochemical shifts: calcium 2.60 mmol / L, inorganic phosphorus 2.04 mmol / L, alkaline phosphatase activity - 130.4 U / L, urine fluorine content - 4.88 mg / day . Excretion of fluorine in urine increased 2.2 times. Remissi of the disease was 6 months.

Example 2. Sick M., 45 years old.

Complained of persistent dull pain in the hip joints, more to the right; knee, shoulder joints, aggravated in the evening, limitation of movement in them, pain in the muscles of the upper and lower extremities, pain in the cervical and lumbar regions of the spine. Sick for about 20 years. She sought medical help in 1972 at the place of residence. A diagnosis was made: deforming arthrosis. She received non-steroidal anti-inflammatory therapy courses, physiotherapy (electrophoresis of novocaine, salicylates, diadynamotherapy, greenery, spa treatment with a short-term effect). Over the past 10 years, it has been deteriorating: muscle pains, spine ache, ceased to notice the effect of treatment.

On examination: the patient is overeating (height 155 cm, weight 95 kg). The general condition is satisfactory. The knee and shoulder joints are deformed; 5 are increased in volume, there is a restriction of movements in them, a gait has been changed: the patient has a limp on his right leg, Pain on palpation of the paravertebral points in the cervical and lumbar spine is noted. From the side of mild changes not noted. The boundaries of the heart are not changed. Pulse 76 beats per minute, satisfactory qualities, blood pressure 130/80 mm RT. Art. Abdominal organs without special features.

Laboratory research data. Complete blood count: HB - 130 g / l, Eg-4.3x x 10-12 /, 1-5.6-109 / l, E-1. P-1, s-68. l-24, m - 6, ESR - 10 mm / hour. General analysis

0 urine: beats. weight 1020, no protein, single L in the field of vision. Blood fibrinogen 3100, CRP (-) neg., Malen's test (-) neg. Biochemical studies: serum calcium - 1.78 mmol / l, inorganic

5 phosphorus - 0.72 mmol / l, alkali activity. phosphatase - 68.85 U / l, fluorine in the urine 2, 13 mg / day. X-ray data:

Hip radiography,

of the knee and shoulder joints: the occurrence of a spine of the throat with a distinctly pronounced. pointedness of the edge sections of the subxndralnuh plates, the articular ends of the braids that form the joint; flattening of the pineal glands, small osteophytic growths along the edges of the joint 5 BOB, subchondral sclerosis. Diagnosis: primary deforming osteoarthrosis of the II stage, FNi: osteochondrosis of the cervical and lumbar spine with predominant lesions of the discs Cs - Ce, Sat - C.

0 15 electrophoresis procedures were carried out for a 5% manganese sulfate solution using the general method. After the first course notes the disappearance of pain in the hip and shoulder joints, there was some

5 . limitation of mobility in the knee sous. tawah. After 23 days, the second course

electrophoresis of 5% sulfate solution

manganese (15 treatments), after which

received 10 sessions of acupuncture reflexotherapy and 10 sessions of superficial acupuncture paravertebral. After a complex of physiotherapeutic treatment, he notes the disappearance of pain in all joints, does not limp, is restored

5 working capacity. Clinical changes are confirmed by blood biochemical data: calcium - 2.52 mmol / L, inorganic phosphorus - 1.98 mmol / L, alkaline phosphatase activity - 113.20 U / L, urine fluorine content - 4.51 mg / day. Excretion of fluorine in urine increased 2.1 times.

The achieved therapeutic effect was noted and after 6 months, which allows us to propose the treatment according to the claimed method 2 times a year to ensure stable remission of the pathological process.

The proposed method was the treatment of 30 patients with deforming osteoarthrosis.

Effective control of the process of excretion of fluorine compounds deposited in supporting tissue (bones, ligamentous apparatus) by saturating the body with manganese by electrophoresis of its salts in a known manner by the general method has been achieved. Saturation with manganese induces activity of the nervous system at all levels, thereby probably increasing the sensitivity of biologically active points and realizing the therapeutic effect of And RT.

Thus, the proposed method has a general regulatory effect mainly on mineral metabolism, which is pathogenetically justified under the conditions of the development of endemic osteoarthritis.

The method is indicated for therapeutic and prophylactic measures in foci endemic for fluorosis to remove deposited fluoride from the body. It can be used to treat patients with advanced arthrosis by conducting only one course of electrophoresis of a 5% solution of manganese sulfate in combination with RTI.

The method is nontoxic and physiological, simple when executed on the basis of the Central Hospital or preventative care, economical and effective in the treatment of patients with endemic arthrosis I - And degree.

 . ...-. . -. .

Claims (1)

SUMMARY OF THE INVENTION A method for the treatment of deforming arthrosis, comprising complex treatment with electrophoresis of the metal for 10-20 minutes in a course of 10 to 20 procedures, the same and so on. that, in order to treat arthrosis caused by an increase in the content of Fluoride in the body, electrophoresis of a 5% sulfate solution is carried out manganese, while the electrode-anode is placed in the interscapular region, and the bifurcated electrode-cathode is applied to the calf muscle region. Two courses of electrophoresis are carried out with an interval between them of 20-40 days, after the second course 10 daily sessions of reflexotherapy are carried out, including superficial acupuncture of paravertebral regions at the level of Co g - Ci - Ls - Si no 5 - 7 min s the subsequent exposure to needles by the inhibitory method on the corporal way of the acupuncture points that stimulate mineral metabolism ,,