RU1816423C - Device for detecting nystagmus parameters - Google Patents

Description

The invention relates to the field of medicine and medical technology, and can be used in the field of otolorology, neuropathology and neurosurgery. l The purpose of the invention is to increase "the accuracy of measurements by automating the process of selecting the analyzed sections of the nystagmus response of the patient."

The goal is achieved as follows.

The proposed device has features common to the prototype: root-potential potential sensor, amplifier, voltage matching device, registration unit, n threshold elements, n formers, AND, OR, NOT elements, decoders, indication unit, trigger, generator, total amplitude counter nystagmus, a counter of the number of nystagmus cycles and a counter of time intervals.

Distinctive features of the proposed device, ensuring the achievement of the goal: a mode switch, first and second keys, a polarity detection unit, a single vibrator, a pulse counter, a pulse shaper and a print unit, while the output of the root-potential potential amplifier is connected to the information input of the first key, which controls the input connected to the output of the mode switch and the control input of the second key, and the output through the polarity determination unit to the second input of the coordinator by voltage NIJ addition output of the first shaper is connected to the count input of a monostable multivibrator and via a reset input of the counter

00

cЈ

Јь

Yu

with

pulses, the low-order output connected to the discharge outputs of the total nystagmus amplitude counter, the counter of the number of nystagmus cycles and the time interval counter, and the erased bit output - with its control input, and also through a pulse shaper with a control input of the print unit, the information inputs of which respectively connected to the bit outputs of the counter of the total amplitude of the nystagmus, the counters of the number of nystagmus cycles and the counter of time intervals, as well as with an information input in key, the output connected to the input trigger start and stop. In FIG. 1 shows a structural diagram of the proposed device; in FIG. 2 is a block diagram of voltage matching device 4; in FIG. 3 is a structural diagram of a start and stop trigger 13.

A device for recording nystagmus parameters comprises; cortical potential sensor 1, amplifier 2, registration unit 3, voltage matching device 4, threshold elements, shapers 6i-6n, element OR 7, elements I 8, 16, 1.4, total amplitude counter nystagmus 9, decoder unit 10, display unit 11, element NOT 12, start and stop trigger 13, counter of the number of nystagma cycles 15, pulse generator 17, counter of time intervals 18, mode switch 19, first 20 and second 21 keys, polarity detection unit 22, one-shot 23 , pulse counter 24, pulse shaper 25, block print 26.

The sensor 1 is connected to an amplifier 2, the output connected to the input of the registration unit 3 and the first input of the coordinator 4, the output of which is connected to the inputs of n threshold elements 5, the outputs of which are connected to the input of the pulse shapers 6, the n outputs of which are connected to the inputs of the element OR 7, and the output OR element 7 is connected to the first input of AND element 8, the output of which is connected to a total amplitude counter of nystagmus 9, the output of which is bitwise connected to the second input of the decoder unit 10, the second output of which is connected to the fourth input of the unit and indication 11, and the second input of the first element And 8 is connected to the output of the start and stop trigger 13. In addition, the output of the start and stop trigger 13 is connected to the first input of the third element And 16, as well as to the input of the element NOT 12, as well as to the first input display unit 11 and with the first input of the second element I / I 14, the second input of which is connected to the output of the first

shaper 61, and the output of the second element And 14 is connected to the input of the counter of the number of nystagmine cycles 15, the outputs of which are bitwise connected to the first

the input of the decoder unit 10, the first output of which is connected to the third input of the display unit 11, in addition, the second input of the third element And 16 is connected to the second pulse generator 17, and the output of the third element And 16 is connected to the input of the counter of time intervals 18, the outputs of which are broken the bottom is connected to the third input of the decoder unit 10, and the third output of the decoder unit

5 10 is connected to the fifth input of the indicating unit 11, the second input of which is connected to the output of the element NOT 12. The output of the amplifier 2 is connected to the information input of the first key 20, which controls the input of the mode switch 19 connected to the output and the second key control input 21, and the output through the polarity detection unit 22 is connected to the second input of the voltage matching device 4. Output

5 of the first driver 6i is connected to the counting input and through a single vibrator 23 to the discharge input of the pulse counter 24, the low-order output connected to the discharge inputs of the total amplitude counter of nystagmus 9, the counter of the number of nystagma cycles 15. And the counter of time intervals 18, and the output of the senior bit yes - with its control input and also via a pulse shaper 25 s

5 by the control input of the print unit 26, the information inputs of which are respectively connected to the bit outputs of the total amplitude counter of nystagmus 9, the counter of the number of nystagmal cycles

0 15 and the counter of time intervals 18, and also, with the information input of the second key 21, the output connected to the input of the trigger start and stop 13.

The voltage coordinator 4 contains: a key 27, an OR element 28, an adjustable amplifier 29 and a switch 30. In this case, the information input of the key and the first input of the OR element 28 are respectively connected to the first and second inputs of the coordinator, and the second input of the OR element 28 is connected to the output of the switch 30, the first and second inputs connected respectively to a common bus and plus bus power supply + Un.n., in addition

5, the output of the OR element 28 is connected to the control input of the key 27 by the output connected through an adjustable amplifier 29 to the output of the coordinator.

The start and stop trigger 13 contains: an inverter 31, a control button 32, and

D-flip-flop 33, whose R-input is directly connected to the input of the start and stop trigger, and S-input - through inverter 31, while the inverse output of the D-flip-flop is connected to its D-input, and the synchronization input C is connected to the output control buttons 32, normally closed and open contacts connected respectively to a common bus And a bus + Un.n., 1 wherein the direct output of the D-trigger is connected to the output of the start and stop trigger.

A device for recording nystagmus ° parameters in the automatic selection mode of the analyzed sections of the nystagmus response of the patient (standby) works as follows.

: The mode switch 19 is set to the position enabling the potential input to the control inputs of the keys 20 and 21. After that, the device is ready to receive and record information from the root potential sensor 1. This information is a nystagmus that occurs in patients spontaneously or the result of various effects on the maze.

Vestibular nystagmus is characterized by the duration, frequency, amplitude and speed of the slow component (see A. B. Kurashvili and V. I. Babi. Physiological functions of the vestibular system. Leningrad: Medicine, Leningrad Department, 1970, pp. 44-45) .

The frequency of nystagmus is the number of nystagmus cycles (tremors) per unit time. According to experimental data f nystagmus from one to three fluctuations in 1-2 s.

The amplitude of nystagmus in different individuals can range from 150 to 900 uV. During registration, an amplifier is calibrated to normalize this parameter. The appearance of a series of oscillations at the amplifier output, the amplitude of which exceeds a certain minimum, may indicate the onset of a nystagmus response in the patient.

The speed of the slow component of nystagmus is a secondary parameter, because it is determined by the formula based on data on the number of nystagmus cycles, their total amplitude and duration of the nystagmus reaction.

So, the condition for starting the device may be the presence at the amplifier output of the root-root potential of nystagmus jerks of a certain amplitude and frequency. In this case, it is also necessary to determine the polarity of the amplified signal so that, if necessary, it should be switched at the first input of the coordinator

7 by voltage, which ensures the operability of subsequent circuit nodes.

Thus, when a patient experiences a nystagmus response in 5 patients, the signal from the output of the amplifier 2 through the open first key 20 is fed to the input of the polarity determination unit 22, at the output of which a potential is formed that controls 10 the voltage matching device 4. This potential is supplied to the first input of the OR element 28 (see Fig. 2), the second input of which receives a signal from the switch 30 in the case of manual registration. Depending on the polarity (vectoriality) of the nystagmus or the position of the switch 30 (in manual mode), the signal from the output of the OR element 28, acting on the control input of the key 27, provides switching of the input signal received at its information input in this way so that the phase of the signal taken from the output of the key 27 remains unchanged when the polarity of the nystagmus changes. Next, the signal 5 is fed to the input of an adjustable amplifier 29, the output of which is also the output of the voltage matching device 4 (Fig. 1). At the same time, a 0-staged reaction of the patient is displayed on the chart tape of the registration unit 3.

Normalized in amplitude and phase, the signal from the output of the coordinator 4 is fed to the inputs of n threshold elements 5, which, in succession, act on the inputs of n formers b, the outputs connected to the inputs of the element OR 7. The threshold elements 51 -5p are configured in such a way that the amplitude of each nystagmus cycle corresponds to a certain number of pulses at the output of the OR element 7. From the output of the first shaper 6i, which corresponds to the minimum amplitude of the nystagmus, the pulses also go to the counting input of the counter Single May 24 pulses and the input monostable 23, which in the initial state supported on blowdown input 24 of the counter potential pulses, retaining it in the zero state. The first pulse at input 0 of the one-shot 23 transfers it for the time T 2 s to the opposite state, i.e., potentials are set at the control V-input and the reset R-input of the 24-pulse counter, which ensure its operation in - 5 counting mode pulses arriving at the counting Twhod. If the signals corresponding to the nystagmus response in the patient actually come from amplifier 2, then the pulses at the input of the single-shot 23 will appear at least once every 2 s.

each time while prolonging the time delay of the single-shot 23 for a period of at least 2 s.

Already the second pulse at the input of counter 24 will lead to the appearance of the lowest bit of a logic level at its output, which will reset the total amplitude of the nystagmus, counter 15 to the number of nystagmus cycles, and the counter 18 to the interval time, preparing them for reception regular information. If after this, two more pulses arrive at the input of the counter 24 pulses, then a logic level will be set at its high-order output, which will prohibit the operation of the counter 24 at the control V-input in the counting mode and put it into the information storage mode. At the same time, through the second key 21 opened earlier, the signal from the high-order output of the pulse counter 24 will be input to the trigger trigger 13, which will trigger and enable the device to operate in the nystagmus registration mode. In this case, the pulses from the output of the OR element 7, the first driver 6i and the 1.7 second pulse generator will affect the first inputs of the And 8, 14, 16 elements, respectively, and the resolving potential from the output of the start and stop trigger 13 will affect their second inputs (see Fig. 3). As a result, the signals from the outputs of the elements AND 8.14, 16 go to the counted inputs of the counters 9, 15.18, respectively.

With the arrival of subsequent nystagmus cycles (jerks), the process will continue. The accumulation of information in a total amplitude counter 9, a counter 15 in the number of nystagmal cycles and a counter in 18 time intervals, as well as their decryption in the decoder unit 10. If the patient's nystagmic reaction stops completely or enters into the mode of single jolts, which is not characteristic of a typical reaction, then the one-shot 23 will return to its original state and zero the counter 24 pulses. At this moment, the pulse shaper 25 is triggered and a pulse is generated that controls the mode of the printing unit 26. That is, the information accumulated by the counters 9.15, 18, and arriving at the information inputs of the printing unit 26 will be printed. At the same time, the same information will be displayed on the display unit 11, controlled by the inverter 12 from the output of the start and stop trigger 13, which will be reset. Thus, the registration process is terminated.

  If the patient resumes a nystagmus reaction, the preparation and registration process is repeated in the same order as the operator is not involved.

Therefore, for each characteristic area of the nystagmus reaction displayed on the chart tape of the recording device 3, there will be a printout on the printing unit 26. To put the device into manual control mode, it is necessary to set the mode switch 19 to the position providing closing of the first 20 and second 21 keys. In this case, starting and stopping the device

5 is performed using the control button 32 i (see Fig. 3), and the phase switching of the LE signal (key to the information input of the key 27: (see Fig. 2) is carried out using the switch 30. The operation of the device in manual mode the choice of the analyzed areas of the nystagmus reaction of the patient is fully consistent with the work of the prototype.

As a result of the introduction of an automated mode during registration, it is possible to carry out studies for a long time without fear of missing one or another burst of nystagmus response in the patient, which increases the accuracy of measurements, and ultimately the diagnosis.

Claims (3)

SUMMARY OF THE INVENTION 1. A device for recording nystagmus parameters, comprising a sequence of 5 non-connected root-potential sensor, an amplifier and a voltage matching device, n groups of threshold elements whose inputs are connected and connected to the output of the matching bodies by the voltage connected in series with the shapers whose outputs are connected to the corresponding inputs of the OR element, series-connected the first AND element, the first input 5 of which is connected to the output of the OR element, a counter of the total amplitude of the nystagmus, a decoder unit and a registration unit connected in series to the second AND element, the first input of which is connected to 0 to the output of the first driver, and counters of the number of nystagmus cycles, the output of which is connected to the second input of the decoder unit, the pulse generator is connected in series, the third 5th element AND counter of time intervals, the output of which is connected to the third input of the decoder unit, a start and stop trigger, the output of which is connected to the second inputs of the AND elements, the second input of the display unit and the input of the element NOT. the output of which is connected to the third input of the display unit, the second and third outputs of the decoder unit are connected to the fourth and fifth inputs of the display unit, which, in order to improve the measurement accuracy by automating the process of selecting the analyzed sections of the nystagmenous patient response, it introduced a mode switch, two keys, the control inputs of which are connected to the output of the mode switch, a polarity determination unit, the input of which is connected to the output of the first key, and the output -jc to the second input is consistent Ate voltage, the print unit, the pulse shaper, the output of which is connected to the control input of the print block, a pulse counter and a single vibrator, the input of which is connected to the output of the first shaper and the counting input of the pulse counter, and the output - with its reset input, while the information input the first key is connected to the amplifier output, the low-order output of the pulse counter is connected to the reset inputs of the counters of the total amplitude of the nystagmus, the number of unstaged cycles and time intervals, and the high-order output is connected to the input th pulse shaper, an information input of the second switch and the control input of the pulse counter, and the data inputs of the printing unit connected to the outputs of counters total 0 5 0 5 0 the amplitude of nystagmus, the number of nystagmal cycles and time intervals. 2. The device according to claim 1, characterized in that the voltage matching device comprises a second OR element, a third key and an adjustable amplifier, the output of which is the input of the matching device, as well as a two-position switch, the changeover contact of which is connected to the second input of the second OR element, and two other contacts are connected respectively to the common wire of the device and the output of the power source, the information input of the third key is the first input of the coordinator, and the first input of the second element OR - by his second entrance. 3. The device according to claim 1; characterized in that the start and stop trigger comprises an inverter, a D-trigger, the direct output of which is the output of the start and stop trigger, and a control button, the changeover contact of which is connected to the synchronization input D- trigger, normally closed contact is connected to the common wire of the device, and normally open is connected to the output of the power source, the unit installation input of the D-trigger is connected to the inverter output, the inverse output is connected to the D-input, and the input is connected to the inverter input and at the same time is trigger input start and stop. FIG. 3.