RU1796143C - Device for measuring recovery time of oxygen partial pressure in tissue in post-ischemia period - Google Patents

Abstract

Usage: in medicine, for the diagnosis of impaired oxygen dynamics in living tissues. The inventive device for determining the time of restoration of the partial pressure of oxygen in the tissue in the post-ischemic period contains a voltage source 1 connected through a current meter 2 to a polarographic sensor 3, an indicator 4, an analog-to-digital converter 5 connected via a data bus 6 to a digital comparator 7 and two registers 8 and 9, which are also connected through a switch 10 to a digital comparator 7, a logical AND-NOT 11 logic element, a counting trigger 12 and counters 13, a cat output It is connected to indicator 4, a control pulse setter 14, the resolution outputs of which are connected to register recording enable inputs, and a gating output is connected to the first input of an NAND 11 element and a counting pulse generator, the output of which is connected to a counter, an analog-to-digital converter, and a setter control pulses, the output of the current meter 2 is connected to an analog-to-digital converter 5, the output of the counting trigger 12 is connected to the third input of the switch 10, and the output of the digital comparator 7 is connected to the second input of the logic element AND NOT 11. Purpose: Reduce the time of the determination procedure. 1 ill. (L C

Description

The invention relates to medicine and can be used to diagnose impaired oxygen dynamics in living tissues.

Devices are known (polygraphs PPT-1 and PU-1), by which it is possible to obtain polarograms with further determination on their basis of dynamic characteristics of the change in the partial pressure of oxygen in the tissue.

These devices are difficult to maintain, require tuning, the output information is a graph of a polarogram requiring additional mathematical processing to obtain the desired oxygen dynamics and, therefore, additional time spent on the entire determination procedure.

The aim of the invention is to reduce the time of the determination procedure,

This goal is achieved by the fact that in the device for determining the partial pressure of oxygen in the tissue, containing a voltage source connected via a current meter to a polarographic sensor and an indicator, an analog-to-digital converter is added, connected via a data bus to a digital comparator and two registers, which are also connected via a switch to a digital comparator, sequentially connected AND-NOT logic element, counting trigger and counter, the output of which is connected to an indicator, a control pulse regulator, the resolution outputs of which are connected to the register recording enable inputs, and the gating output is connected to the first input of the IN-H element and a counting pulse generator, the input of which is connected to a counter, an analog-to-digital converter, and a pulse pickup control, while the output of the current meter is connected to an analog-to-digital converter, the output of the counting trigger is connected to the third input of the switch, and the output of the digital comparator is connected to the second input of the NAND gate.

The drawing shows a functional diagram of the proposed device.

The device contains a voltage source 1 connected through a current meter 2 to a polarographic sensor 3, an indicator 4, an analog-to-digital converter 5. connected via a data bus 6 to a digital comparator 7 and two registers 8 and 9, which are connected via a switch 10 also connected to the digital comparator 7, the AND-NOT 11 logic element, the counting trigger 12 and the counter 13, the output of which is connected to

indicator 4, the control pulse setter 14, the resolution outputs 15 and 16 of which are connected to the recording enable inputs of registers 8 and 9, and the gating output 17 is connected to the first input of the AND-NOT 11 element, the counter pulse generator 18, the output of which is connected to the counter 13, an analog-to-digital converter 5 and a control pulse setter 14, while the output of the current meter 2 is connected to an analog-to-digital converter 5, the output of the counting trigger 12 is connected to the third input of the switch 10, and the output of the digital comparator 7 is connected to the second input of the logic element This AND NOT 11, in addition, the control pulse adjuster 14 has an input 19 to which the Start signal is applied.

The device operates as follows.

The polarographic sensor 3 is connected to the test object, regional ischemia is created at the object, the partial pressure of oxygen in the tissue begins to drop. A start signal is applied to the input 19 of the control pulse generator 14. After a fixed time interval (1 min) necessary for the end of transient processes in the sensor-object system, a pulse is generated at the output 15 of the control pulse setter 14, which writes the code of the current current value to register 8 (the value of the recorded current is proportional to the partial pressure of oxygen in the tissue of the object at a given time). After a time interval of 1 min, a pulse is generated at the output 16 of the control pulse setter 14, which records the code of the current current value in register 9. Then, the ischemia is held for 10 minutes and removed, the partial pressure of oxygen in the tissue begins to be restored, and the controller 14 of the control pulses generates at the gate output 17 pulses synchronized with the start frequency of the analog-to-digital converter 5, which are fed to the first input of the AND-NOT 11 element. In the initial state, the output counts trigger 12 is a low-level signal, while register 9 is connected to the inputs of the digital comparator 7 through the switch 10. At the moment of the coincidence of the codes at the inputs A and B of the digital comparator 7, a high-level signal appears at its output, while at the clock input of the counting of the trigger 12, a voltage drop is formed which switches the trigger and a high level signal appears at its output. The operation of the counter 13 is allowed, and the switch 10 connects the register 8 to the inputs B of the digital comparator 7. The next time the codes on the inputs A and B of the digital comparator 7 match, which corresponds to the moment the initial value of the partial pressure of oxygen is restored to the fabric, the second switch of the counting trigger 12 occurs and the filling of the counter 13 is stopped. The counting result is displayed on the indicator 4. When the frequency of the counting pulse generator 18 is 1, (period O, 01 min), the counting result is the time restored and partial oxygen pressure in the tissue in the postischemic period, measured in minutes with an accuracy of 0.01 min.

The result obtained does not require additional mathematical processing and can be used to diagnose impaired oxygen dynamics in living tissues.

The proposed device, unlike the prototype, provides the shortest possible time of the entire procedure for determining the desired index. Selected Form

presentation of the final result (the time of restoration of the partial pressure of oxygen in the tissue, measured in minutes) allows you to use it as a measure of the deliverable by the theme or other types

pathology of the studied object.

Claims (1)

SUMMARY OF THE INVENTION A device for determining the time of restoration of the partial pressure of oxygen in tissue in the postischemic period, comprising a voltage source connected via a current meter to a polographic probe, and an indicator, which, in order to shorten the time of the determination procedure, an analog-to-digital converter is introduced into it, connected via a data bus to a digital comparator and two registers, which are also connected through a switch to a digital comparator, connected in series ennye logic element AND-NOT, a counting trigger and a counter, the output of which is connected to the indicator, a control pulse generator, the resolution outputs of which are connected to the register enable inputs, and the gating output to the first input of the AND-NOT element, and the counter pulse generator, the output of which connected to a counter, an analog-to-digital converter and a control pulse generator, while the output of the current meter is connected to an analog-to-digital converter, the output of the counting trigger to the third input of the switch, and the output of the digital comparator to the second input of the logical element AND NOT.