RU157740U1 - DEVICE FOR DIAGNOSIS AND TREATMENT OF CARDIOVASCULAR DISEASES - Google Patents

Abstract

A device for the diagnosis and complex treatment of cardiovascular diseases, containing a block of electrodes made in the form of an induction coil, a switching unit, a data input unit, a digital-to-analog converter unit, to the input-output of which removable cartridges are connected, in the form of disposable test strips, and also containing a block for generating a therapeutic signal, a block for controlling and storing information, a drug selector and an autonomous power supply, characterized in that the device additionally includes a block of sensors-applicators for measuring ECG signals, a block for switching ECG sensors, a block for an analog-to-digital converter of ECG signals, as well as a block of optical sensors for taking a photoplethysmogram, a block of an analog-to-digital signal converter from optical sensors and an antenna-inductor, while the block of electrodes is connected to a switching block connected to a data input block, a digital-to-analog converter block, a drug selector, a block for forming a medical a signal and a control and information storage unit connected in turn to a switching unit, a data input unit, a therapeutic signal generation unit and through an ECG sensor switching unit connected to an analog-to-digital converter unit connected to an applicator unit for measuring ECG signals, in addition, connected to the block of optical sensors for taking a photoplethysmogram through the block of an analog-to-digital signal converter from optical sensors, while the control and information storage block is connected to the antenna-inductor, which is also connected to the block for forming the treatment

Description

The utility model relates to medical equipment, namely to equipment for cardiovascular surgery and cardiology, and can be used for diagnosis and complex treatment, due to exposure to the patient with low-intensity electromagnetic radiation of cardiovascular diseases, including remotely online.

A device for the treatment of low-intensity electromagnetic radiation of coronary heart disease, including myocardial infarction (patent for PM No. 123671, IPC A61N 1/00, publ. 01/10/2013), containing a block of electrodes, a switching unit, a data input unit, digital-to-analog converter unit, a unit for changing resonant characteristics, a medical selector, a control unit and a computer interface, a power supply unit. When using this device, the parameters of electromagnetic stimulation are determined by the state of the patient. The attending physician carries out programming of the device and downloads the program from the personal computer to the device data input unit through the control unit and a computer interface.

The disadvantage of this device is that its use allows the treatment of only coronary heart disease and only after the patient is diagnosed with the disease based on the results of laboratory and instrumental research methods. In addition, it was not possible to evaluate the treatment and, if necessary, to adjust it.

The technical result of the proposed utility model is to enable both diagnosis and evaluation of the treatment of cardiovascular diseases and, if necessary, its adjustment.

The technical result is achieved by the fact that in a device for the diagnosis and complex treatment of cardiovascular diseases, containing a block of electrodes made in the form of induction coils, a switching unit, a data input unit, a digital-to-analog conversion unit, to the input-output of which removable cartridges are connected, in the form of a one-time test strip, as well as containing a block for generating a medical signal, a control unit and information storage, a medical selector and an autonomous power supply, an additional sensor unit has been introduced ikov-applicators for measuring ECG signals, an ECG sensor switching unit, an analog-to-digital converter of ECG signals, as well as an optical sensor unit for taking photoplethysmograms, an analog-to-digital signal converter from optical sensors and an antenna inductor, while the electrode block is connected to a switching unit connected to a data input unit, a digital-to-analog converter unit, a drug selector, a treatment signal generating unit, and an information management and storage unit connected in turn, with a switching unit, a data input unit, a treatment signal generating unit, and through an ECG sensor switching unit connected to an analog-to-digital converter unit connected to an applicator-sensor unit for measuring ECG signals, furthermore connected to an optical sensor unit for photoplethysmogram recording through the block of an analog-to-digital converter of signals from optical sensors, while the control and information storage unit is connected to the antenna inductor, which is also connected to the unit Nia therapeutic signal and the power supply and has inputs and outputs are made as connectors for memory cards and a USB port. Distinctive features of the proposed device from the prototype are the following: an antenna inductor (8), a block of sensor applicators for ECG measurement (9), an ECG sensor switching unit (10), an analog-to-digital ECG signal converter (11), a block are introduced into the device circuit optical pickups

 photoplethysmograms (12), analog-to-digital converter of the photoplethysmogram signal (13).

The advantage of the proposed device is that by analyzing the physiological parameters of the patient’s body while studying photoplethysmography and electrocardiography, it is possible to diagnose a cardiovascular disease, in addition, in parallel with the treatment with low-intensity electromagnetic fields with an individual algorithm, it is possible to evaluate the treatment, as well as , if necessary, make adjustments to the current treatment regimen. The next advantage of using the device is the ability to remotely monitor and correct the treatment if necessary.

The antenna inductor is an induction coil with a flat arrangement of turns. Since the antenna works in the near field, the patient is exposed mainly to the magnetic component of the electromagnetic field, which allows, if necessary, not to use the electrode block.

An electrocardiographic (ECG) study made it possible to record cardiac abnormalities, the effectiveness of antiarrhythmic therapy, and the diagnosis of myocardial ischemia.

These photoplethysmograms (PPG) made it possible to draw a conclusion about the adaptive capabilities of the body, the level of mobilizing potential, the level of hormonal modulation of regulatory mechanisms, the balance of anabolic and catabolic processes, the optimal or non-optimal mode of functioning of the rhythm control centralization system, stress index, and to assess the state of endothelial function.

In FIG. 1 is a structural diagram of a device for diagnosing and treating cardiovascular diseases, comprising a block of electrodes for signal collection (1), a switching unit (2), a data input unit (3), a digital-to-analog signal converter (4), a unit for generating treatment signal (5), drug selector (6), control and information storage unit (7), inductor antenna (8), sensor applicator unit for measuring ECG signals (9), ECG signal switching unit (10), unit analog to digital converter with ECG (11), optical unit yes tors FIGs remover (12), analog-to-digital converter PPG signal (13), the lithium-ion battery (14).

In FIG. 2 shows the appearance of the device, including a housing (15), an indication device (16), configured to enter data using the touch keyboard, a memory card slot (17), a connector for connecting electrodes (18), analog-digital input-output signal converter from the electrodes, made in the form of a connector for connecting removable cartridges (19), a connector for connecting electrodes with an ECG (20), a connector for connecting PPG electrodes (21), a USB port connector for connecting to a computer (22), a power button off (23).

Modeling of the device is as follows.

A body (15) is made of shockproof plastic. An indication device (16) with a virtual keyboard is arranged on the front surface of the device. On the upper end surface there is a connector for a memory card (17), a connector for connecting electrodes (18), a connector for connecting removable cartridges (19), a connector for connecting sensors with an ECG (20), a connector for connecting sensors with PPG signals (21) . On the lower end side there is a USB connector for connecting to a computer (23), as well as an on-off button (24).

A switching unit (2), a data input unit (3), a digital-to-analog converter unit (4), a unit for generating a treatment signal (5), a medical selector (6), a control and information storage unit (7) are installed in the housing (15) ), antenna inductor (8), switching unit for ECG (10), analog-to-digital signal converter with ECG (11), analog-to-digital signal converter FPG (13), lithium-ion battery (14).

In this case, the switching unit (2) is connected to the electrode unit (1), the data input unit (3), the digital-to-analog converter unit (4), the control and information storage unit (7), the unit for generating the treatment signal (5), and the drug selector (6); a data input unit (3) is connected to a switching unit (2), a digital-to-analog converter (4), a control and information storage unit (7); a digital-to-analog converter unit (4) is connected to a switching unit (2) and to a control and information storage unit (7); a unit for generating a treatment signal (5) is connected to a switching unit (2), a control and information storage unit (7), and an antenna to an inductor (8); a medical selector (6) is connected to a switching unit (2), a control unit and information storage (7); a control and information storage unit (7) is connected to a switching unit (2), a data input unit (3), a digital-to-analog converter unit (4), a treatment signal generating unit (5), a drug selector (6); an antenna inductor (8) is connected to a unit for generating a treatment signal (5) and a control unit and information storage (7); an ECG sensor switching unit (10) is connected to an analog-to-digital signal converter unit with an ECG (11) and to a control and information storage unit (7); the block of the analog-to-digital signal converter with PPG (13) is connected to the control unit and information storage (7).

The device operates as follows.

The proposed device allows both the diagnosis of cardiovascular disease, followed by treatment, due to exposure to the patient with low-intensity electromagnetic radiation, and in parallel with the treatment with low-intensity electromagnetic fields with an individual algorithm, to evaluate the treatment and, if necessary, make adjustments to ongoing treatment regimen. To do this, turn on the device with the on / off button (23). In this case, the device monitors its functioning from the control unit and information storage (7). Upon completion of the self-diagnosis, the display device (16) indicates the device is ready for operation or a message about detected errors, and the device goes into standby mode. In the diagnosis, before treatment and in monitoring the treatment, a study of PPG and ECG is performed. For this, an ECG and PPG sensor block is connected to the apparatus; using the virtual keyboard, information is entered from the control and information storage unit (7) and the corresponding actions are performed: to remove the PPG, the optical sensor (12) is attached to the index finger (it can be on any) of the patient. The recorded signal is transmitted through an analog-to-digital converter of the FPG signal (13) and enters the control and information storage unit (7).

If it is necessary to evaluate endothelial function, 2 optical PPG sensors are used, attached to the index fingers of both hands. Analysis of PPG taken from both fingers before and after an occlusion test allows us to judge the state of endothelial function.

In parallel with this, standard sensors-applicators for ECG measurement (9) are attached in the heart region in an amount of 5-6, the signals from which are sent to the ECG sensor switching unit (10) and through the analog-to-digital signal converter with ECG (11) enters the block management and storage of information (7). At the same time, ECG and PPG recording is turned on.

For screening studies, recording within 5-6 minutes is sufficient. If necessary, this study can be carried out up to 24 hours. After the end of the study, the results are transmitted via a USB port of the computer to the doctor (remote transmission), possibly online. The latter evaluates the results and, if necessary, adjusts the therapy algorithm.

The therapeutic effect algorithm, developed individually for each patient, with the selection of the exposure mode is entered into the information input unit (3) and is set from the control and information storage unit (7). Remote adjustment of the therapy algorithm is possible when connecting the device via a USB port (22) to a remote computer.

Studies have confirmed good results in the treatment of cardiovascular diseases due to exposure to the patient with low-intensity electromagnetic radiation, which is confirmed by numerous works [9-14].

Then the doctor, or the patient himself, on the instructions of the doctor, selects the necessary therapeutic effect, connects the necessary external devices - electrodes made in the form of an induction coil, with the working side adjacent to the patient’s body and glued with Velcro, or without them, and test strips, or use antenna inductor.

The treatment signal generating unit (5) is a radio transmitting device operating at a frequency carrying from 16 to 30 MHz and with amplitude modulation of the carrier. The modulating signal parameters are selected according to the therapy algorithm. Radiation power no more than 5 MW.

In operation with connected electrodes:

since human vibrations (signals) are of an electromagnetic nature, they are registered using the electrode block (1); the control and information storage unit (7) carries out the coordinated connection of the electrode unit (1), as well as the connection of the switching unit (2) and the drug selector (6) to the treatment signal generating unit (5), according to the therapeutic effect algorithm stored in the control device and information storage (7). After special treatment (spatio-temporal, frequency, nonlinear filtering, separation), the vibrations with the help of conductors, contacts and the electrode block (1) return to the patient. The patient’s electromagnetic field immediately responds to these therapeutic signals, and the corrected vibrations are sent back to the device, etc. During therapy, the patient and the device form a closed loop of adaptive regulation, as a result of which the processed oscillations return to the patient again and again. Upon completion of the therapeutic effect, the corresponding information is displayed on the display device (16), and the device goes into standby mode.

In operation with the connection of the antenna-inductor:

The antenna inductor (8) is an induction coil with a flat arrangement of turns. Since the antenna operates in the near field, the effect on the patient is mainly the magnetic component of the electromagnetic field.

The treatment signal generating unit generates an electrical signal with parameters according to the information received from the control and information storage unit, then this signal is fed to the inductor antenna.

Thus, when using this device, the parameters of electromagnetic stimulation are determined by the state of the patient himself, while the effect is maximally individualized, which suggests that this device provides an optimally controlled treatment option.

After a treatment session, the data of the physiological parameters of the patient’s body, with the simultaneous examination of the PPG and ECG are processed, and, if necessary, appropriate changes are made to the therapy algorithm. In addition, there is the possibility of remote online correction of treatment and monitoring of treatment, by connecting the device via the computer’s USB port and via the Internet, the device is connected to the remote computer (with the doctor).

Example. 1. ACUTE CORONARY SYNDROME

An electrocardiographic and photoplethysmographic study is carried out for a patient with acute coronary syndrome, along with a laboratory (general blood test, blood biochemistry, coagulogram, spectrometric characteristics of the blood) and instrumental (echocardiogram) studies. To do this, connect the ECG sensor block and the sensor block to remove the FIG and connect the device to the on / off button. At the same time, the device monitors its functioning from the control unit and information storage (7). Upon completion of the self-diagnosis, the display device (16) indicates the device is ready for operation or a message about detected errors, and the device goes into standby mode. To take the photoplethysmogram, the optical sensor (12) is attached to the index finger (can be any) of the patient. The recorded signal is transmitted through an analog-to-digital converter of the FPG signal (13) and enters the control and information storage unit (7). If it is necessary to evaluate endothelial function, 2 optical PPG sensors are used, attached to the index fingers of both hands. Analysis of PPG taken from both fingers before and after an occlusion test allows us to judge the state of endothelial function.

In parallel, standard sensors-applicators for measuring ECG (9) are attached in the heart region in an amount of 5-6, the signals from which are sent to the switching unit of ECG sensors (10) and through an analog-to-digital signal converter with ECG (11) enter control unit and information storage (7). At the same time, ECG and PPG recording is turned on.

Using the virtual keyboard, information on the results of laboratory (general blood analysis, blood biochemistry, coagulogram, spectrometric characteristics of the blood) and instrumental (echocardiogram) studies of patient N., who had acute myocardial infarction, is entered from the control and information storage unit (7).

Based on the results of the study, the attending physician conducts programming of the device, based on multifactor modeling of the therapy algorithm for acute myocardial infarction. Treatment is aimed at reducing the risk of thrombosis, relieving spasm of coronary vessels, and reducing pain. Programming is performed using the developed software, which allows to individualize the treatment algorithm for a specific patient.

The therapeutic effect algorithm, developed individually, is downloaded by the doctor from the personal computer via the computer’s USB port to the data input unit (3) through the information management and storage device (7). To conduct a therapeutic effect, an applicator sensor block (1) is connected to the device and the device is turned on using the on / off button (23), while the device monitors its operation from the control and information storage device (7) and the status of connected external devices (1 ) Upon completion of the self-diagnosis, the device’s readiness for operation or a message about detected errors is indicated on the display device (16), and the device enters standby mode, then, from the display device (16), the therapeutic effect necessary for the patient is selected to reduce coagulation, taking into account its individual indicators, 2 electrodes (1) are fixed on the patient’s body, which are made in the form of an induction coil, with the working side adjacent to the patient’s body and glued with Velcro, and test-p glosses with the blood of an individual to adjust the algorithm of treatment issued by the program, and then launch a therapeutic impact on execution. During therapy, the information management and storage device (7) coordinatedly connects an external test strip, as well as a drug selector (6) to the treatment signal generating device (5), according to the therapeutic effect algorithm in the range from 1 to 100 Hz stored in the device management and storage of information (7). The choice of the optimal exposure regimen that affects the repair processes in acute myocardial infarction is carried out in accordance with the recommendations for patients after acute myocardial infarction [19, 27, 30, 31].

Upon completion of the therapeutic effect, the corresponding information is displayed on the display device (16), and the device goes into standby mode.

The second treatment option is possible without the use of electrodes, but with the inclusion of an antenna inductor. At home or in the hospital, the device is turned on using the on / off button (23), while the device monitors its operation from the control and information storage device (7). Upon completion of the self-diagnosis, the display device (16) indicates the device is ready for operation or a message about detected errors, and the device enters standby mode. To conduct therapy from the display device (16), using the selected command typed using the virtual keyboard from the control unit and information storage (7), the therapeutic effect necessary for the patient is selected to reduce coagulation, taking into account its individual indicators. At the same time, the apparatus is positioned so that the apparatus body with the antenna-inductor is located on the surface of the body, on the projection of the heart. Since the antenna operates in the near field, the effect on the patient is mainly the magnetic component of the electromagnetic field. During therapy, the control unit and information storage (7) generates an electromagnetic signal with the necessary parameters, and then this signal is fed to the antenna inductor.

When adjusting the therapeutic effect, after a treatment session, a photoplethysmographic and electrocardiographic study is repeated, the indicators of which are sent to the control and information storage unit (7), the data of which are displayed on the display device. The doctor analyzes the results and decides on the need for treatment adjustment. Correction data is also entered into the data block of the control and information storage device (7) using the virtual keyboard.

Example 2. Hypertension. Diagnosis and treatment.

Hypertension is one of the most common diseases of the cardiovascular system. The causes of hypertension can be different. These include dysfunctions of the internal organs: liver, adrenal kidneys, etc. One of the main causes of hypertension is the overstrain of higher nervous activity under the influence of psychoemotional influences [6, 20, 25].

The use of low-intensity electromagnetic fields as part of the complex therapy of hypertension is possible at all stages of the disease, which will contribute to more effective treatment, reduction of side effects of drug therapy, due to lower doses of drugs, and in the initial stage of the disease, there is no need to prescribe drug therapy [ 1, 5, 6, 8, 9, 15, 16, 18, 22, 24].

The feasibility of using low-intensity electromagnetic fields as part of the complex treatment of hypertension is also that in the presence of a not deeply developed endothelial dysfunction, there is the possibility of its correction [21].

Currently, it is generally recognized that successful treatment of hypertension is possible with the help of agents that reduce the activity of the sympathetic nervous system by improving the functions of the higher parts of the brain [1, 3, 4, 20, 22, 24]. So, for example, the inclusion in the complex therapy of low-intensity electromagnetic oscillations of frequencies 5.5, 9.5 Hz, contributes to the antiangiospastic effect. The parasympathetic effect is achieved by using a frequency of 6 Hz. If it is necessary to obtain a diuretic effect, it is possible to connect the frequency spectrum in the range of 8.10, 86 Hz, the hypotensive effect of 3.3-9.5 Hz. For the regulation of diuresis, the balance of potassium, sodium, it is possible to use a frequency of 8.1 Hz. In magnesium deficiency, the use of a frequency of 62.5 Hz [7].

A patient with hypertension, along with laboratory and instrumental studies, conduct electrocardiographic and photoplethysmographic studies. For this, the ECG sensor block (9) and the sensor block for removing the PPG (12) are connected to the device and the device is turned on by the on-off button (23). In this case, the device monitors its functioning from the control unit and information storage (7). Upon completion of the self-diagnosis, the display device (16) indicates the device is ready for operation or a message about detected errors, and the device goes into standby mode. To take the photoplethysmogram, the optical sensor (12) is attached to the index finger (can be any) of the patient. The recorded signal is transmitted through an analog-to-digital converter of the FPG signal (13) and enters the control and information storage unit (7). If it is necessary to evaluate endothelial function, 2 optical PPG sensors are used, attached to the index fingers of both hands. Analysis of PPG taken from both fingers before and after an occlusion test allows us to judge the state of endothelial function.

In parallel with this, standard sensors-applicators for ECG measurement (9) are attached in the heart region in an amount of 5-6, the signals from which are sent to the ECG sensor switching unit (10) and through the analog-to-digital signal converter with ECG (11) enters the block management and storage of information (7). At the same time, ECG and PPG recording is turned on.

Using the virtual keyboard, information on the results of laboratory (general blood analysis, blood biochemistry, coagulogram, spectrometric blood characteristics) and instrumental (echocardiogram) studies of patient A., with hypertension, is entered from the control and information storage unit (7).

Based on the results of the study, the attending physician performs programming of the device based on multifactor modeling of the therapy algorithm for hypertension. The treatment is aimed at correcting psychoemotional overstrain and disturbances in the trophism of the central nervous system, leading to pathologically increased excitability of the hypothalamic structures and the reticular formation of the brain is to include the hypothalamus frequency spectrum (7.5, 15, 100 Hz, pituitary gland (92.5, 99, 91.5, 98 Hz), the limbic system (5, 26.5 Hz), the use of programs in the rhythms of the brain [7]. Our previous experimental studies on the influence of low-intensity electromagnetic fields (b resonance therapy) on the process of normalizing morphofunctional changes in the rat hippocampus during inhalation halothane anesthetic and false operation showed a positive effect on the normalization of the morphofunctional state of neurons in rat hippocampus CA1 / CA3 fields after a false operation under halotan anesthesia [2].

Programming is performed using the developed software, which allows to individualize the treatment algorithm for a specific patient.

The therapeutic effect algorithm, developed individually, is downloaded, as directed by the doctor, from the personal computer via the USB port (22) to the data input unit (3) via the information management and storage device (7). To conduct a therapeutic effect, the applicator sensor block (1) is connected to the device and the device is turned on using the on / off button (23), while the device monitors its operation from the control and information storage device (7) and the status of connected external devices (1) . Upon completion of the self-diagnosis, the device is ready to work or a message about detected errors is indicated on the display device (16), and the device goes into standby mode, then, from the display device (16), the therapeutic effect necessary for the patient is selected, taking into account its individual indicators, on the patient’s body 2 electrodes (1) are fixed, which are made in the form of an induction coil, with the working side adjacent to the patient’s body and glued with Velcro, and the test strip is connected with the patient’s blood for correction ovki individual treatment algorithm issued by the program, and then launch a therapeutic impact on execution. During therapy, the information management and storage device (7) makes a coordinated connection of the external test strip, as well as the drug selector (6) to the treatment signal generating device (5), according to the therapeutic effect algorithm, in the range from 1 to 100 Hz, stored in information management and storage device (7). Upon completion of the therapeutic effect, the corresponding information is displayed on the display device (16), and the device goes into standby mode.

The second treatment option is possible without the use of electrodes, but with the inclusion of an antenna inductor. At home or in the hospital, the device is turned on using the on / off button (23), while the device monitors its operation from the control and information storage device (7). Upon completion of the self-diagnosis, the display device (16) indicates the device is ready for operation or a message about detected errors, and the device enters standby mode. To conduct therapy from the display device (16), using the selected command typed using the virtual keyboard from the control and information storage unit (7), the therapeutic effect necessary for the patient is selected, aimed at correcting the psychoemotional overstrain and disturbance of trophism of the central nervous system, leading to pathologically increased the excitability of hypothalamic structures and the reticular formation of the brain lies in the inclusion in the regime of complex therapy of the frequency spectrum of the hypothalamus (7.5, 15, 100 Hz, the pituitary gland (92.5, 99, 91.5, 98 Hz), the limbic system (5, 26.5 Hz), the use of programs in the rhythms of the brain, correction of endothelial dysfunction, taking into account its individual indicators. The apparatus is thus positioned so that the apparatus body with an antenna The inductor was located on the surface of the body (for example, in a pocket). Since the antenna works in the near zone, the patient is exposed mainly to the magnetic component of the electromagnetic field. During therapy, the control unit and information storage (7) generates an electromagnetic signal with the necessary parameters, and then this signal is fed to the antenna inductor.

When adjusting the therapeutic effect, after a treatment session, a photoplethysmographic and electrocardiographic study is repeated, the indicators of which are sent to the information control and storage unit (7), the data of which are displayed on the display device (16). The doctor analyzes the results and decides on the need for treatment adjustment. Correction data is also entered into the data block of the control and information storage device using the virtual keyboard.

An individual approach to treatment is achieved by the fact that if it is necessary to achieve the effect necessary in a particular case (hypotensive, antihistamine, hypoglycemic, anti-stress, antiarrhythmic, parasympathetic, etc.), frequency spectra with the desired effect are included in the complex of treatment programs.

Example 3. Chronic heart failure

According to the Guideline study [29], the prevalence of chronic heart failure (CHF) in the United States and Western Europe ranges from 1% to 3%. In Russia, mortality rates from heart and vascular diseases are 3.5 times higher than in developed European countries [17]. Endothelial vasomotor dysfunction is an early sign of endothelial cell dysfunction, characterized by a decrease in nitric oxide production. It is believed that the progression of heart failure may be the result of a sharp decrease in the synthesis of nitric oxide (NO) by vascular endothelial cells [28]. Therefore, the possibility of correcting endothelial dysfunction using low-intensity electromagnetic fields in patients with chronic heart failure seems to us an important and promising direction.

We conducted a study to study the effect of low-intensity electromagnetic fields of endogenous origin on endothelial function in patients with chronic heart failure with FC II NYHA. As a result of the study, it was found that in this group of patients the vasomotor function of the endothelium is impaired, indicating a decrease in vasodilating substances (nitric oxide synthesis) by endothelial cells. Under the influence of low-intensity electromagnetic fields of endogenous origin (endogenous bioresonance therapy), an improvement in microcirculation parameters was observed, indicating a vasodilator effect. A decrease in the parameter of neurogenic tone to normal values indicates a possible regulatory effect of this type of treatment [4].

An electrocardiographic and photoplethysmographic study is performed along with a laboratory and instrumental study for a patient with heart failure. For this, the ECG sensor block (9) and the sensor block for removing the PPG (12) are connected to the device and the device is turned on by the on-off button (23). In this case, the device monitors its functioning from the control unit and information storage (7). Upon completion of the self-diagnosis, the display device (16) indicates the device is ready for operation or a message about detected errors, and the device goes into standby mode. To take the photoplethysmogram, the optical sensor (12) is attached to the index finger (can be any) of the patient. The recorded signal is transmitted through an analog-to-digital converter of the FPG signal (13) and enters the control and information storage unit (7). If it is necessary to evaluate endothelial function, 2 optical PPG sensors are used, attached to the index fingers of both hands. Analysis of PPG taken from both fingers before and after an occlusion test allows us to judge the state of endothelial function.

In parallel with this, standard sensors-applicators for ECG measurement (9) are attached in the heart region in an amount of 5-6, the signals from which are sent to the ECG sensor switching unit (10) and through the analog-to-digital signal converter with ECG (11) enters the block management and storage of information (7). At the same time, ECG and PPG recording is turned on.

Using the virtual keyboard, the results of laboratory (general blood analysis, blood biochemistry, coagulogram, spectrometric blood characteristics) and instrumental (echocardiogram) studies of patient B., with chronic heart failure, are entered from the control and information storage unit (7).

Based on the results of the study, the attending physician performs programming of the device based on multifactor modeling of the algorithm for the treatment of chronic heart failure.

The treatment is aimed at correcting psychoemotional overstrain and disturbances in the trophism of the central nervous system, leading to pathologically increased excitability of the hypothalamic structures and the reticular formation of the brain is to include the hypothalamus frequency spectrum (7.5, 15, 100 Hz, pituitary gland (92.5, 99, 91.5, 98 Hz), limbic system (5, 26.5 Hz), the use of programs in the rhythms of the brain, correction of endothelial dysfunction, taking into account its individual indicators.

Programming is performed using the developed software, which allows to individualize the treatment algorithm for a specific patient.

The therapeutic effect algorithm, developed individually, is downloaded by a doctor from a personal computer via a USB port (22) to a data input unit (3) through an information management and storage device (7). To conduct a therapeutic effect, the applicator sensor block (1) is connected to the device and the device is turned on using the on / off button (23), while the device monitors its operation from the control and information storage device (7) and the status of connected external devices (1) . Upon completion of the self-diagnosis, the device is ready to work or a message about detected errors is indicated on the display device (16), and the device goes into standby mode, then, from the display device (16), the therapeutic effect necessary for the patient is selected, taking into account its individual indicators, on the patient’s body 2 electrodes (1) are fixed, which are made in the form of an induction coil, with the working side adjacent to the patient’s body and glued with Velcro, and the test strip is connected with the patient’s blood for correction ovki individual treatment algorithm issued by the program, and then launch a therapeutic impact on execution. During therapy, the information management and storage device (7) makes a coordinated connection of the external test strip, as well as the drug selector (6) to the treatment signal generating device (5), according to the therapeutic effect algorithm, in the range from 1 to 100 Hz, stored in information management and storage device (7). Upon completion of the therapeutic effect, the corresponding information is displayed on the display device (16), and the device goes into standby mode.

The second treatment option is possible without the use of electrodes, but with the inclusion of an antenna inductor. At home or in the hospital, the device is turned on using the on / off button (23), while the device monitors its operation from the control and information storage device (7). Upon completion of the self-diagnosis, the display device (16) indicates the device is ready for operation or a message about detected errors, and the device enters standby mode. To conduct therapy from the display device (16), using the selected command typed using the virtual keyboard from the control and information storage unit (7), the therapeutic effect necessary for the patient is selected, aimed at correcting the psychoemotional overstrain and disturbance of trophism of the central nervous system, leading to pathologically increased the excitability of hypothalamic structures and the reticular formation of the brain lies in the inclusion in the regime of complex therapy of the frequency spectrum of the hypothalamus (7.5, 15, 100 Hz, pituitary gland (92.5, 99, 91.5, 98 Hz), limbic system (5, 26.5 Hz), the use of programs in the rhythms of the brain, correction of endothelial dysfunction, taking into account its individual indicators.

At the same time, the apparatus is positioned so that the apparatus body with the inductor antenna is located on the surface of the body on the projection of the target organ (heart). Since the antenna operates in the near field, the effect on the patient is mainly the magnetic component of the electromagnetic field. During therapy, the control unit and information storage (7) generates an electromagnetic signal with the necessary parameters, and then this signal is fed to the antenna inductor.

When adjusting the therapeutic effect, after a treatment session, a photoplethysmographic and electrocardiographic study is repeated, the indicators of which are sent to the information control and storage unit (7), the data of which are displayed on the display device (16). The doctor analyzes the results and decides on the need for treatment adjustment. Correction data is also entered into the data block of the control and information storage device (7) using the virtual keyboard.

An individual approach to treatment is achieved by the fact that if it is necessary to achieve the effect required in a particular case (hypotensive, antihistamine, hypoglycemic, anti-stress, antiarrhythmic, parasympathetic, etc.), frequency spectra with the desired effect are included in the complex of treatment programs.

In all cases of conducting a therapy session, the data of the physiological parameters of the patient’s body, with the simultaneous study of PPG and ECG are processed, and if necessary, the necessary changes are made to the therapy algorithm. In addition, it is possible to remotely consult online about the correction and control of the treatment, by connecting the device via the computer’s USB port and connecting the device to the remote computer via the Internet.

Bibliography

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Claims (1)

A device for the diagnosis and comprehensive treatment of cardiovascular diseases, containing a block of electrodes made in the form of an induction coil, a switching unit, a data input unit, a digital-to-analog converter unit, to the input-output of which removable cartridges are connected, in the form of disposable test strips, and also containing a medical signal generating unit, a control and information storage unit, a medical selector and an autonomous power supply unit, characterized in that the sensor-app unit is additionally introduced into the device ikators for measuring ECG signals, an ECG sensor switching unit, an analog-to-digital ECG signal converter unit, as well as an optical sensor unit for taking a photoplethysmogram, an analog-to-digital signal converter from optical sensors and an antenna inductor, while the electrode unit is connected to a switching unit connected to a data input unit, a digital-to-analog converter unit, a medical selector, a treatment signal generating unit, and a control and information storage unit connected in its own right with a switching unit, a data input unit, a treatment signal generating unit, and through an ECG sensor switching unit connected to an analog-to-digital converter unit connected to an applicator-sensor unit for measuring ECG signals, in addition, connected to an optical sensor unit for capturing photoplethysmograms through the block of an analog-to-digital signal converter from optical sensors, while the control and information storage unit is connected to the antenna inductor, which is also connected to the forming unit bnogo signal and the power supply and has inputs and outputs are made as connectors for memory cards and a USB port.

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