RS61592B1 - Magnezijumlitospermat b visoke čistoće i postupak njegove pripreme - Google Patents

Magnezijumlitospermat b visoke čistoće i postupak njegove pripreme

Info

Publication number
RS61592B1
RS61592B1 RS20210192A RSP20210192A RS61592B1 RS 61592 B1 RS61592 B1 RS 61592B1 RS 20210192 A RS20210192 A RS 20210192A RS P20210192 A RSP20210192 A RS P20210192A RS 61592 B1 RS61592 B1 RS 61592B1
Authority
RS
Serbia
Prior art keywords
preparation
method therefor
purity magnesium
magnesium lithospermate
lithospermate
Prior art date
Application number
RS20210192A
Other languages
English (en)
Inventor
Lijiang Xuan
Yiping Wang
Weibin Song
Chunguang Chen
Dingxiang Li
Xiaoyu Zhou
Yunlong Gu
Liang Hu
Jing Zhao
Wenwei Xu
Shumei Wang
Original Assignee
Shanghai Inst Materia Medica Cas
Shanghai Green Valley Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Inst Materia Medica Cas, Shanghai Green Valley Pharmaceutical Co Ltd filed Critical Shanghai Inst Materia Medica Cas
Publication of RS61592B1 publication Critical patent/RS61592B1/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Furan Compounds (AREA)
RS20210192A 2014-04-01 2015-02-09 Magnezijumlitospermat b visoke čistoće i postupak njegove pripreme RS61592B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201410137310.8A CN104974119B (zh) 2014-04-01 2014-04-01 一种高纯度丹酚酸b镁及其制备方法
EP15772459.2A EP3127905B1 (en) 2014-04-01 2015-02-09 High-purity magnesium lithospermate b and preparation method therefor
PCT/CN2015/072539 WO2015149589A1 (zh) 2014-04-01 2015-02-09 一种高纯度丹酚酸b镁及其制备方法

Publications (1)

Publication Number Publication Date
RS61592B1 true RS61592B1 (sr) 2021-04-29

Family

ID=54239374

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20210192A RS61592B1 (sr) 2014-04-01 2015-02-09 Magnezijumlitospermat b visoke čistoće i postupak njegove pripreme

Country Status (6)

Country Link
US (1) US10259798B2 (sr)
EP (1) EP3127905B1 (sr)
JP (1) JP6839540B2 (sr)
CN (1) CN104974119B (sr)
RS (1) RS61592B1 (sr)
WO (1) WO2015149589A1 (sr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105481809B (zh) * 2015-12-29 2018-01-05 山东大学 一种丹酚酸b的分离纯化方法及丹酚酸b镁盐的制备方法
CN111686103A (zh) * 2019-03-11 2020-09-22 中国科学院上海药物研究所 丹参乙酸镁或含有丹参乙酸镁的药物组合物对于肝脏缺血再灌注的保护作用及应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01268682A (ja) * 1988-04-21 1989-10-26 Minofuaagen Seiyaku Honpo:Goushi 腎機能改善剤及びリソスペルミン酸塩の製造方法
JPH02131423A (ja) * 1988-07-08 1990-05-21 Terumo Corp ５−リポキシゲナーゼ作用阻害剤
US6037369A (en) * 1998-06-25 2000-03-14 Georgetown University School Of Medicine Compounds obtained from salvia species having antiviral Activity
US6149915A (en) * 1999-09-29 2000-11-21 Shiva Biomedical, Llc Treatment of diabetic nephropathy and microalbuminuria
CN100536868C (zh) * 2005-08-12 2009-09-09 上海绿谷制药有限公司 高含量丹参多酚酸盐粉针剂及其制备方法
KR100857687B1 (ko) * 2007-03-28 2008-09-08 연세대학교 산학협력단 단삼으로부터 고농도의 마그네슘 리토스퍼메이트 ｂ를 분리하는 방법 및 마그네슘 리토스퍼메이트 b를 함유하는 단삼 추출물을 생산하는 방법.
WO2010022049A1 (en) * 2008-08-19 2010-02-25 Scinopharm Taiwan, Ltd. The derivatives of 8-epiblechnic acid and their effects on down-regulation of endothelin (eta) receptor mrna
CN102058599B (zh) * 2009-11-17 2014-06-04 中国科学院上海药物研究所 丹参多酚酸盐及其制备方法和用途
CN102204955B (zh) * 2011-05-04 2014-04-23 长沙理工大学 一种同时提取丹参中酮类物质和丹酚酸类物质的方法
CN103417526A (zh) * 2012-05-15 2013-12-04 上海绿谷制药有限公司 丹参多酚酸盐在制备肾保护剂药物中的应用

Also Published As

Publication number Publication date
US10259798B2 (en) 2019-04-16
CN104974119A (zh) 2015-10-14
EP3127905A4 (en) 2018-01-03
WO2015149589A1 (zh) 2015-10-08
EP3127905A1 (en) 2017-02-08
JP6839540B2 (ja) 2021-03-10
CN104974119B (zh) 2018-10-19
JP2017510592A (ja) 2017-04-13
US20170137399A1 (en) 2017-05-18
EP3127905B1 (en) 2021-01-27

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