RS20140351A1 - Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereof - Google Patents

Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereof

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Publication number
RS20140351A1
RS20140351A1 RS20140351A RSP20140351A RS20140351A1 RS 20140351 A1 RS20140351 A1 RS 20140351A1 RS 20140351 A RS20140351 A RS 20140351A RS P20140351 A RSP20140351 A RS P20140351A RS 20140351 A1 RS20140351 A1 RS 20140351A1
Authority
RS
Serbia
Prior art keywords
ibuprofen
preparation
emulsion systems
contain
active substance
Prior art date
Application number
RS20140351A
Other languages
Serbian (sr)
Inventor
Ljiljana Đekić
Original Assignee
Ljiljana Đekić
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ljiljana Đekić filed Critical Ljiljana Đekić
Priority to RS20140351A priority Critical patent/RS57803B1/en
Publication of RS20140351A1 publication Critical patent/RS20140351A1/en
Publication of RS57803B1 publication Critical patent/RS57803B1/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Invention herewith described refers to the preparation of the biocompatible micro-emulsion systems having the physicochemical and biopharmaceutical properties of pharmaceutical compositions for topical application with the controlled and/or sustained release of ibuprofen, which is desirable as a prerequisite for maintaining the therapeutic concentration at the site of therapeutic action throughout the complete dosing interval that can be significantly prolonged compared to the conventional medical products. The micro emulsion systems that are the subject of this invention in their structure in addition to Ibuprofen (5%) contain the surfactant (0% - 20%) (the surface-active substance, type Caprylocaproyl macrogolglycerides (EP) or lecithin of vegetable origin), the cosurfactant (0% -55%) (the surface-active substance from the group of alkylphenol ethoxylates (APEO), polysorbates, polyethoxylated derivatives of hydrogenated castor oil and/or poloxamers), the oil phase (ester of C14-C22 monocarboxylic acids and short-chain monohydric alcohols (0%-10%) or vegetable oil (0%-15%)) and an aqueous phase which in addition to purified water (20%-60%) may also contain the viscosity-increasing agent from the group of hydrocolloids (0% -1.5%) and a preservative (0%-0.2%). The invention also provides the methods for the preparation thereof.
RS20140351A 2014-06-30 2014-06-30 Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereof RS57803B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RS20140351A RS57803B1 (en) 2014-06-30 2014-06-30 Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RS20140351A RS57803B1 (en) 2014-06-30 2014-06-30 Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereof

Publications (2)

Publication Number Publication Date
RS20140351A1 true RS20140351A1 (en) 2015-12-31
RS57803B1 RS57803B1 (en) 2018-12-31

Family

ID=55071300

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20140351A RS57803B1 (en) 2014-06-30 2014-06-30 Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereof

Country Status (1)

Country Link
RS (1) RS57803B1 (en)

Also Published As

Publication number Publication date
RS57803B1 (en) 2018-12-31

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