RS20140351A1 - Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereof - Google Patents
Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereofInfo
- Publication number
- RS20140351A1 RS20140351A1 RS20140351A RSP20140351A RS20140351A1 RS 20140351 A1 RS20140351 A1 RS 20140351A1 RS 20140351 A RS20140351 A RS 20140351A RS P20140351 A RSP20140351 A RS P20140351A RS 20140351 A1 RS20140351 A1 RS 20140351A1
- Authority
- RS
- Serbia
- Prior art keywords
- ibuprofen
- preparation
- emulsion systems
- contain
- active substance
- Prior art date
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Invention herewith described refers to the preparation of the biocompatible micro-emulsion systems having the physicochemical and biopharmaceutical properties of pharmaceutical compositions for topical application with the controlled and/or sustained release of ibuprofen, which is desirable as a prerequisite for maintaining the therapeutic concentration at the site of therapeutic action throughout the complete dosing interval that can be significantly prolonged compared to the conventional medical products. The micro emulsion systems that are the subject of this invention in their structure in addition to Ibuprofen (5%) contain the surfactant (0% - 20%) (the surface-active substance, type Caprylocaproyl macrogolglycerides (EP) or lecithin of vegetable origin), the cosurfactant (0% -55%) (the surface-active substance from the group of alkylphenol ethoxylates (APEO), polysorbates, polyethoxylated derivatives of hydrogenated castor oil and/or poloxamers), the oil phase (ester of C14-C22 monocarboxylic acids and short-chain monohydric alcohols (0%-10%) or vegetable oil (0%-15%)) and an aqueous phase which in addition to purified water (20%-60%) may also contain the viscosity-increasing agent from the group of hydrocolloids (0% -1.5%) and a preservative (0%-0.2%). The invention also provides the methods for the preparation thereof.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RS20140351A RS57803B1 (en) | 2014-06-30 | 2014-06-30 | Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RS20140351A RS57803B1 (en) | 2014-06-30 | 2014-06-30 | Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
RS20140351A1 true RS20140351A1 (en) | 2015-12-31 |
RS57803B1 RS57803B1 (en) | 2018-12-31 |
Family
ID=55071300
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20140351A RS57803B1 (en) | 2014-06-30 | 2014-06-30 | Biocompatible micro emulsion systems with controlled release of ibuprofen, their preparation, and application thereof |
Country Status (1)
Country | Link |
---|---|
RS (1) | RS57803B1 (en) |
-
2014
- 2014-06-30 RS RS20140351A patent/RS57803B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
RS57803B1 (en) | 2018-12-31 |
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