GR1008234B - Parenteral formulation of triazole antifungal agent and method for preparation thereof - Google Patents
Parenteral formulation of triazole antifungal agent and method for preparation thereofInfo
- Publication number
- GR1008234B GR1008234B GR20130100315A GR20130100315A GR1008234B GR 1008234 B GR1008234 B GR 1008234B GR 20130100315 A GR20130100315 A GR 20130100315A GR 20130100315 A GR20130100315 A GR 20130100315A GR 1008234 B GR1008234 B GR 1008234B
- Authority
- GR
- Greece
- Prior art keywords
- preparation
- antifungal agent
- parenteral formulation
- triazole antifungal
- active ingredient
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Abstract
The present invention relates to pharmaceutical compositions for parenteral administration comprising Voriconazole or pharmaceutical acceptable salt thereof as the active ingredient and a solubilizing agent such as hydroxypropyl beta cyclodextrin in order to achieve increased solubility of the active ingredient. The present invention also provides a method of preparation of such composition.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20130100315A GR1008234B (en) | 2013-05-27 | 2013-05-27 | Parenteral formulation of triazole antifungal agent and method for preparation thereof |
EP14726076.4A EP3003265A1 (en) | 2013-05-27 | 2014-05-13 | Parenteral formulation of triazole antifungal agent and method for preparation thereof |
PCT/EP2014/001285 WO2014191080A1 (en) | 2013-05-27 | 2014-05-13 | Parenteral formulation of triazole antifungal agent and method for preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20130100315A GR1008234B (en) | 2013-05-27 | 2013-05-27 | Parenteral formulation of triazole antifungal agent and method for preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GR1008234B true GR1008234B (en) | 2014-06-24 |
Family
ID=50792404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20130100315A GR1008234B (en) | 2013-05-27 | 2013-05-27 | Parenteral formulation of triazole antifungal agent and method for preparation thereof |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3003265A1 (en) |
GR (1) | GR1008234B (en) |
WO (1) | WO2014191080A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106232577B (en) | 2014-04-25 | 2019-02-22 | 味之素株式会社 | Immunostimulant |
EP3511318A1 (en) | 2015-10-28 | 2019-07-17 | Ajinomoto Co., Inc. | Immunostimulating agent |
CN113975236B (en) * | 2021-12-08 | 2023-03-31 | 海南鑫开源医药科技有限公司 | Voriconazole dry suspension and preparation process thereof |
CN116570558B (en) * | 2023-06-21 | 2023-12-26 | 广州仁恒医药科技股份有限公司 | Voriconazole ophthalmic nanometer slow-release composition and preparation method and application thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2018866A1 (en) * | 2007-07-27 | 2009-01-28 | Sandoz AG | Pharmaceutical compositions containing voriconazole |
EP2467379B1 (en) * | 2009-08-19 | 2016-03-02 | ratiopharm GmbH | Process for the production of coevaporates and complexes comprising voriconazole and cyclodextrin |
EP2720723B1 (en) * | 2011-06-15 | 2018-04-11 | Synthon BV | Stabilized voriconazole composition |
EP2561863A1 (en) * | 2011-08-22 | 2013-02-27 | Farmaprojects, S.A.U. | Pharmaceutical compositions comprising voriconazole |
-
2013
- 2013-05-27 GR GR20130100315A patent/GR1008234B/en active IP Right Grant
-
2014
- 2014-05-13 EP EP14726076.4A patent/EP3003265A1/en not_active Withdrawn
- 2014-05-13 WO PCT/EP2014/001285 patent/WO2014191080A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
EP3003265A1 (en) | 2016-04-13 |
WO2014191080A1 (en) | 2014-12-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PG | Patent granted |
Effective date: 20140718 |