RO95366B1 - Process for preparing 10,11-dihydro-n,n-dimethyl-5h-dibenzo-(a,d)-cycloheptene-5- hydroxy-5-propylamine - Google Patents
Process for preparing 10,11-dihydro-n,n-dimethyl-5h-dibenzo-(a,d)-cycloheptene-5- hydroxy-5-propylamineInfo
- Publication number
- RO95366B1 RO95366B1 RO126010A RO12601086A RO95366B1 RO 95366 B1 RO95366 B1 RO 95366B1 RO 126010 A RO126010 A RO 126010A RO 12601086 A RO12601086 A RO 12601086A RO 95366 B1 RO95366 B1 RO 95366B1
- Authority
- RO
- Romania
- Prior art keywords
- dibenzo
- dihydro
- cycloheptene
- propylamine
- hydroxy
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- BMVWCPGVLSILMU-UHFFFAOYSA-N 5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-one Chemical compound C1CC2=CC=CC=C2C(=O)C2=CC=CC=C21 BMVWCPGVLSILMU-UHFFFAOYSA-N 0.000 abstract 1
- 238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229940001470 psychoactive drug Drugs 0.000 abstract 1
- 239000004089 psychotropic agent Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Inventia se refera la o metoda de preparare a 10,11-dihidro-N,N-dimetil-5H- dibenzo (a,d) ciclohepten-5-hidroxi-5-propilaminei, intermediar în sinteza unor medicamente psihotrope, printr-o reactie Grignard dintre 10,11-dihidro-5H-dibenzo (a,d) ciclohepten 5-onei si 1,3 dimetil-amonoclorpropan, fara izolarea cetonei dupa prepararea ei printr-o reactie Friedel- Crafts, în stare pura, prin distilare la vid înaintat.The invention relates to a method for the preparation of 10,11-dihydro-N, N-dimethyl-5H-dibenzo (a, d) cycloheptene-5-hydroxy-5-propylamine intermediates in the synthesis of psychotropic drugs Grignard of 10,11-dihydro-5H-dibenzo (a, d) cyclohepten-5-one and 1,3-dimethylaminocloropropane without isolation of the ketone after its preparation by a Friedel-Crafts reaction, submitted.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO126010A RO95366B1 (en) | 1986-12-22 | 1986-12-22 | Process for preparing 10,11-dihydro-n,n-dimethyl-5h-dibenzo-(a,d)-cycloheptene-5- hydroxy-5-propylamine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO126010A RO95366B1 (en) | 1986-12-22 | 1986-12-22 | Process for preparing 10,11-dihydro-n,n-dimethyl-5h-dibenzo-(a,d)-cycloheptene-5- hydroxy-5-propylamine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO95366A2 RO95366A2 (en) | 1988-09-15 |
| RO95366B1 true RO95366B1 (en) | 1988-09-16 |
Family
ID=20120202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO126010A RO95366B1 (en) | 1986-12-22 | 1986-12-22 | Process for preparing 10,11-dihydro-n,n-dimethyl-5h-dibenzo-(a,d)-cycloheptene-5- hydroxy-5-propylamine |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO95366B1 (en) |
-
1986
- 1986-12-22 RO RO126010A patent/RO95366B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO95366A2 (en) | 1988-09-15 |
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